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Biologics: Targets and Therapy

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ISSN: 1177-5491

Journal Articles:

- 599 records -

Optimization of Recombinant Human Interferon-Gamma Expression and Purification in E. coli, and Developing an Immunization Protocol for the Production of Optimal Humoral Response

Uwituze V, Mugasa CM, Namayanja M, Nalumenya DP, Ndayisenga J, Ssekatawa K, Kato CD

Biologics: Targets and Therapy 2026, 20:584180

Published Date: 16 April 2026

Enhancement of Gastric Mucosal Defense by Phytomedicine in the Context of H. pylori–Associated Ulcer Disease

Paulraj RS, Perumal P, Ramachandran A, Sathiyaseelan A

Biologics: Targets and Therapy 2026, 20:597797

Published Date: 14 April 2026

Rheumatoid Factor Beyond Rheumatoid Arthritis: A Potential Marker of Cardiometabolic and Hepatic Risk

Egba SI, Orhonigbe IO, Achi NK, Ikechukwu GC, Chukwu CN, Omeoga CH

Biologics: Targets and Therapy 2026, 20:603345

Published Date: 13 April 2026

Safety and Efficacy of Mesenchymal Stem Cell Therapy in Multiple System Atrophy: Systematic Review

Elimam N, Albarari SS, Shaalan Y, Elsheikh SM, Alzamari AA, Elmekkawi N, Mogahed R, Alghuweiri RH

Biologics: Targets and Therapy 2026, 20:593367

Published Date: 31 March 2026

Anifrolumab in Refractory Oral Manifestations in Systemic Lupus Erythematosus: A Case Report and Literature Review

Garmish O, Smiyan S, Komorovsky R, Bilozetskyi I

Biologics: Targets and Therapy 2026, 20:588071

Published Date: 16 March 2026

Research on the Role of Autophagy in Vascular Endothelial Cells in the Healing of Chronic Refractory Wounds

Riling L, Kunyue F, Liyan G, Yaya W, Baoling N, Jiehui L

Biologics: Targets and Therapy 2026, 20:573844

Published Date: 13 January 2026

Mesenchymal Stem Cell Therapy in Osteoarthritis and Rheumatoid Arthritis: A Systematic Review of Exosomal microRNAs

Hejazian SS, Hejazian SM, Mostafavi Montazeri SS, Abediazar S, Zununi Vahed S, Barzegari A

Biologics: Targets and Therapy 2025, 19:747-785

Published Date: 30 December 2025

Mechanism and Applications of CRISPR/Cas-9-Mediated Genome Editing [Corrigendum]

Asmamaw M, Zawdie B

Biologics: Targets and Therapy 2025, 19:745-746

Published Date: 27 December 2025

Efficacy, Safety, and Cost-Effectiveness of the Infliximab Biosimilar GP-1111 in Patients with Inflammatory Bowel Disease Who Underwent a Nonmedical Switch: A Prospective Cohort Study

Pápista M, Resál T, Bacsur P, Kata D, Farkas B, Bálint A, Fábián A, Bor R, Ivány E, Szepes Z, Farkas K, Juhász Z, Buzás N, Molnár T

Biologics: Targets and Therapy 2025, 19:731-743

Published Date: 18 December 2025

Switch from Intravenous to Subcutaneous Formulation of Tocilizumab in Rheumatoid Arthritis: Retrospective Cohort Analysis and Systematic Literature Review

Galoppini G, Garaffoni C, Lotesoriere A, Nogarin F, Bortoluzzi A, Govoni M, Silvagni E

Biologics: Targets and Therapy 2025, 19:713-727

Published Date: 4 December 2025

Tumor-to-Tumor Metastasis: Breast Cancer Metastasizing to EGFR Exon 19-Mutated Lung Adenocarcinoma with Long-Term Disease-Free Survival

Zhang Y, Hao Y, Yang H, Meng X, Yang S, Wang J, Xie J, Lu P, Ji Y

Biologics: Targets and Therapy 2025, 19:707-712

Published Date: 19 November 2025

In Silico Screening of Streptomyces sp. Metabolites Targeting P. falciparum DHODH and DPCK for Antimalarial Discovery

Hamami SMA, Riswana FR, Fitri LE, Widodo N, Zakaria MNZ, Aththar AF, Khairi ER, Abdullah A, Prasetya DY, Fai M

Biologics: Targets and Therapy 2025, 19:681-705

Published Date: 15 November 2025

Beyond Monotherapy: Exploring the Efficacy and Safety of Dual Biologic Strategies in Rheumatic Diseases

Hassan F, Jeries H, Daood R, Naffaa ME

Biologics: Targets and Therapy 2025, 19:665-680

Published Date: 8 November 2025

Efficacy of Belimumab on Different Joint and Skin Manifestations of Systemic Lupus Erythematosus: Real-Life Data from a New Multicentric, Nationwide Italian Cohort (BeRLiSS-JS 2.0)

Bracalenti M, Zen M, Bianchi B, Bortoluzzi A, Brussino L, Castrignanò P, Cauli A, Cavagna L, Chessa E, Chiara E, De Angelis R, De Marchi G, Di Carlo M, Emmi G, Galvagni I, Gasparotto M, Gatto M, Gerli R, Govoni M, Lo Gullo A, Nano A, Negrini S, Noviello S, Orsolini G, Pazzola G, Piga M, Quartuccio L, Rossini M, Salvarani C, Silvagni E, Silvestri E, Tamussin M, Tizian M, Tomietto P, Urban ML, Vacca A, Doria A, Iaccarino L

Biologics: Targets and Therapy 2025, 19:651-663

Published Date: 30 October 2025

Antibody-Based Therapeutics for Hypercholesterolemia

Tomlinson B, Chan P

Biologics: Targets and Therapy 2025, 19:631-649

Published Date: 27 October 2025

The Dual Role of the TRAIL-DR5 Signaling Axis in Cardiovascular Disease: From Molecular Mechanisms to Targeted Therapies

Cao R, Qi W, Huang X, Zheng Y, Zheng R, Ma Y, Zhang H

Biologics: Targets and Therapy 2025, 19:613-629

Published Date: 25 October 2025

Irisin Research Landscape (2012–2024): A Bibliometric and Visual Analysis of Evolving Hotspots and Future Trends

Gao L, Sun W, Shi H, Zhu W, Wang H, Wang J

Biologics: Targets and Therapy 2025, 19:595-611

Published Date: 22 October 2025

The Potential of Telitacicept in Treating Lupus erythematosus panniculitis: A Case Report

Xie X, Tang S, Huang M

Biologics: Targets and Therapy 2025, 19:585-593

Published Date: 7 October 2025

Dual Blocking of IL17A and IL36R for the Treatment of Refractory Hidradenitis Suppurativa: A Case Report

Yu Y, Li J, Liu H, Sun Y, Zhang F

Biologics: Targets and Therapy 2025, 19:581-584

Published Date: 3 October 2025

Migrasomes: A New Role in Disease Diagnosis and Treatment

Zhang X, Wang S, Jiang Y, Zhu W, Yang Y, Huo L, Zhang Y, Zhou Y, Yang Z, Wang X

Biologics: Targets and Therapy 2025, 19:561-579

Published Date: 2 October 2025

siRNAs, tRNAs, and rRNAs in Osteoarthritis: Biological Functions and Therapeutic Opportunities

Wang M, Dai Y, Ge X, Zheng L, Zhai M, Li W, Liu G, Cheng X, Wei J, Yang X, Liu L, Liu H, Sun J, Li B, Yuan F

Biologics: Targets and Therapy 2025, 19:539-560

Published Date: 3 September 2025

Enhancing Early Detection of Pancreatic Cancer in Genetically Predisposed Individuals: Integrating Advanced Imaging Modalities with Emerging Biomarkers and Liquid Biopsy

Abdel-Razeq R, Mansour A, Barbar M, Abu Shanap M, Sharaf B, Tamimi F, Mansour R, Muhanna A, Al-Othman Y, Hammad H, Shakhatreh M, Mahafdah S, Bani Hani H, Abdel-Razeq H

Biologics: Targets and Therapy 2025, 19:511-523

Published Date: 30 August 2025

Therapeutic Potential of Compounds with High Affinity to BAG2 in Inhibiting Keloid Disease

Wang Y, Yuan Z, Zhou R, Lu L, Wang X, Yang J

Biologics: Targets and Therapy 2025, 19:497-510

Published Date: 24 August 2025

What’s New and What’s Next in Fecal Microbiota Transplantation?

Baydoun H, Hussain N, Wu KO, Kelly CR, Fischer M

Biologics: Targets and Therapy 2025, 19:481-496

Published Date: 21 August 2025

Update on Biologic Therapy in Juvenile Idiopathic Arthritis: A Five-year Narrative Review

Civino A, Diomeda F, Burrone M, Natoli V, Ravelli A

Biologics: Targets and Therapy 2025, 19:425-441

Published Date: 23 July 2025

Brodalumab for Moderate-to-Severe Psoriasis: A Comprehensive Review of Efficacy, Safety, and Clinical Positioning

Babaei N, Gill M, Cervantes M, Kim D, Yang S, Wu JJ

Biologics: Targets and Therapy 2025, 19:415-422

Published Date: 15 July 2025

Effects of Dulaglutide in Doxorubicin Induced Renal Toxicity in Rats

Hama Said HJ, Ahmed ZA

Biologics: Targets and Therapy 2025, 19:399-412

Published Date: 3 July 2025

IRAK4 Targeting: A Breakthrough Approach to Combat Hidradenitis Suppurativa

Zhang H, Liu Z, Qin B, Cheng D, Chen P, Bi X

Biologics: Targets and Therapy 2025, 19:387-397

Published Date: 30 June 2025

Marstacimab for the Treatment of Hemophilia A or B

Mahlangu J

Biologics: Targets and Therapy 2025, 19:379-386

Published Date: 24 June 2025

Positioning Guselkumab in The Treatment Algorithm of Patients with Crohn’s Disease

D’Amico F, Bencardino S, Magro F, Dignass A, Gutiérrez Casbas A, Verstockt B, Hart A, Armuzzi A, Peyrin-Biroulet L, Danese S

Biologics: Targets and Therapy 2025, 19:351-363

Published Date: 31 May 2025

From Conventional to Advanced Therapies: A National Health Registry Report (2016-2022) on DMARDs in Rheumatoid Arthritis Treatment in Turkey

Ata N, Satış H, Küçükşahin O, Karabulut E, Ayan G, Erden A, Bilgin E, Armağan B, Tecer D, Babaoğlu H, Sarı A, Kılıç L, Ülgü MM, Ayvalı MO, Birinci Ş, Kalyoncu U

Biologics: Targets and Therapy 2025, 19:331-339

Published Date: 26 May 2025

Generalized Pustular Psoriasis with Cushing’s Syndrome: A Case of Effective Spesolimab Treatment

Peng G, Zhang Y, Zhang S, Li Y, Luo L, Luo J, Nie X, Zhang H, Liao C

Biologics: Targets and Therapy 2025, 19:321-329

Published Date: 10 May 2025

Boswellia carteri Birdw. Resin Extract Induces Phase-I Cytochrome P-450 Enzyme Gene Expressions in Human Hepatocarcinoma (Hep G2) Cells: In vitro and in silico Studies

Alghamdi SS, Albahlal HN, Alajmi RS, Alsharidah A, Almogren A, Suliman R, Alehaideb ZI

Biologics: Targets and Therapy 2025, 19:289-320

Published Date: 5 May 2025

Adalimumab Biosimilars Demonstrate Long-Term Durability and Cost-Effectiveness in Paediatric Inflammatory Bowel Disease: A Real-World Two-Centre European Cohort Study

Ancona S, Armstrong K, Longo C, Rabone R, Merrick V, Henderson P, Gandullia P, Wilson DC, Arrigo S, Russell RK

Biologics: Targets and Therapy 2025, 19:265-279

Published Date: 29 April 2025

Epigenetic Regulation of Sorbitol Dehydrogenase in Diabetic Retinopathy Patients: DNA Methylation, Histone Acetylation and microRNA-320

Amin R, Permana H, Kartasasmita AS, Hilmanto D, Hidayat R

Biologics: Targets and Therapy 2025, 19:251-264

Published Date: 28 April 2025

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