Breast Cancer: Targets and Therapy

Breast Cancer Biomarkers in Diagnostic and Translational Pathology

Breast cancer diagnostics has undergone a significant transformation with the expanding integration of immunohistochemistry-based biomarker assessment into routine pathology practice. Beyond traditional morphologic classification, contemporary evaluation increasingly incorporates predictive and prognostic markers. In breast pathology, biomarkers such as hormone receptors and HER2 have long served as foundational tools; however, recent developments have broadened this landscape to include more nuanced categories of expression and emerging targets. This Article Collection focuses on investigating immunohistochemical and molecular biomarker testing in breast cancer, with particular emphasis on optimizing reproducibility and standardization in routine practice.