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Breast Cancer: Targets and Therapy
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Archive: Volume 18, 2026
The Impact of Androgen Receptor Expression on Neoadjuvant Therapy in HER2-Positive Breast Cancer
Tian C, Qiu J, Fan Y, Yu H, Liu S
Breast Cancer: Targets and Therapy 2026, 18:595222
Published Date: 12 May 2026
ADPB Sensitivity in Breast Cancer is Correlated with LAT1 Expression: An in vitro Study of a Novel Theranostic Candidate
Kusumahstuti KP, Holik HA, Bashari MH, Achmad A, Shamsuddin S, Kartamihardja AHS
Breast Cancer: Targets and Therapy 2026, 18:564513
Published Date: 7 May 2026
Immune Checkpoint Blockade and Emerging Combination Platforms in Breast Cancer: A Narrative Review
Abbaspour M, Esmaeil N, Akbari V, Ghoreishi M, Rafiepoor H
Breast Cancer: Targets and Therapy 2026, 18:588323
Published Date: 5 May 2026
Efficacy, Safety, and Prognostic Factors of Dalpiciclib Combined with Endocrine Therapy After Progression on CDK4/6 Inhibitors in Patients with HR+/HER2- Advanced Breast Cancer: A Retrospective Study
Zhou S, Yao R, Zhang M, Jiang M, Liu J, Li M, Ma F, Pan B, Li Q
Breast Cancer: Targets and Therapy 2026, 18:589939
Published Date: 4 May 2026
Hematologic Glyco-Signatures: Emerging Blood-Based Sugar Codes Linked to Hyper-Aggressive Breast Cancer
Obeagu EI
Breast Cancer: Targets and Therapy 2026, 18:603801
Published Date: 1 May 2026
Uncertainty-Aware Machine Learning for Predicting Axillary Lymph Node Metastasis Using Breast MRI
Ünal S, Gürfidan R
Breast Cancer: Targets and Therapy 2026, 18:599211
Published Date: 1 May 2026
Genetic Correlation of miR-423 Polymorphism rs8067576 with Progression and Prognosis of Triple-Negative Breast Cancer
Pan H, Huang Z, Li A, Li M, Li Y, Lin Y, Cai J
Breast Cancer: Targets and Therapy 2026, 18:577378
Published Date: 30 April 2026
Multi-Omics Characterization of ABHD12 Across Pan-Cancer and Validation of Its Role in Promoting Proliferation and Metastasis in Breast Cancer
Zhao J, Gou Y, Wang Y, Li Y, Ma H, Xing Y, Peng H, Guo C
Breast Cancer: Targets and Therapy 2026, 18:554836
Published Date: 29 April 2026
Clinical Relevance of USP44 Expression and DNA Methylation Status in Breast Cancer Cell Lines, Tumor Tissues, and Circulating Tumor DNA
Park KT, Lee NR, Jeong YJ
Breast Cancer: Targets and Therapy 2026, 18:599533
Published Date: 28 April 2026
Novel Insights into the Oncogenic Role and Clinical Significance of ORC6L in Breast Cancer
Jiang X, Wang S, Wei Q, Yang Y, Chen Y, Chen S
Breast Cancer: Targets and Therapy 2026, 18:586715
Published Date: 20 April 2026
From Axillary Lymph Node Dissection to Sentinel Node Biopsy in Breast Cancer: A 23-Year Population-Based Large-Sample Study with Long-Term Survival Outcomes
Mangone L, Marinelli F, Bisceglia I, Braghiroli MB, Neri A, Morabito F, Pinto C, Ragazzi M, Ferrari G, Coiro S, Cenini E
Breast Cancer: Targets and Therapy 2026, 18:573154
Published Date: 17 April 2026
LINC01128 Affects Triple-Negative Breast Cancer Progression Through Targeting miR-32-5p
Xiong M, Yang Q, Cheng L, Yu L, Hu Y
Breast Cancer: Targets and Therapy 2026, 18:596228
Published Date: 16 April 2026
Capecitabine versus Paclitaxel After CDK4/6 Inhibitor Progression in Hormone Receptor–Positive, HER2-Negative Metastatic Breast Cancer: A Real-World Study
Birsin Z, Güren AK, Aliyev V, Guliyev M, Jeral S, Cebeci S, Çerme E, Günaltılı M, Abbasov H, Çiçek E, Atak S, Sarı M, Demirci NS, Alan Ö
Breast Cancer: Targets and Therapy 2026, 18:598598
Published Date: 15 April 2026
HER2 Overexpression in Invasive Breast Carcinoma in the Democratic Republic of Congo and its Association with Selected Clinicopathological Characteristics
Ilunga Nday G, Ilunga Banza M, Umpungu AN, Kabamba Nzaji M, Moyambe JNT
Breast Cancer: Targets and Therapy 2026, 18:600288
Published Date: 15 April 2026
Single-Cell Profiling Reveals a Treg-Rich, NK Cell-Depleted Immune Microenvironment in Triple-Negative Breast Cancer with High-Glucocorticoid Receptor Expression
Behar J, Shiang C, Dolcen DN, Bennett LB, DeVilbiss AW, Matossian MD, Chan IS, Nanda R, Conzen SD, Lafin JT
Breast Cancer: Targets and Therapy 2026, 18:569936
Published Date: 14 April 2026
Adjuvant Weekly Paclitaxel and Trastuzumab for HER2-Positive Early-Stage Breast Cancer with Preserved Baseline LVEF: Incidence of Cardiotoxicity and Feasibility of Simplified Cardiac Surveillance
Tsunoda A, Mizuno T, Nakamori S, Ichikawa M, Tono Y, Saito K, Tawara I
Breast Cancer: Targets and Therapy 2026, 18:596107
Published Date: 13 April 2026
Analysis of Factors Related to Lymph Node Metastasis Following Neoadjuvant Chemotherapy for Breast Cancer: Correlation Between Plasma Exosomal Circular RNA and Metastasis
Ma S, Huang Y, Yang Q, Liu X, Zhang Z, Yan B
Breast Cancer: Targets and Therapy 2026, 18:588196
Published Date: 9 April 2026
Bridging Clinical Trials to Real-World Clinical Practice: TCHP Neoadjuvant Therapy Outcomes in HER2-Positive Breast Cancer
Sharaf B, Seif A, Bani Hani H, Alhasan M, Khader R, Al-Yag’oub M, Ghanem A, Bani Ata J, Ajlouni B, Jawarneh Q, Jaffal A, Tamimi F, Jehad S, Al-Abdallat H, Mahafdah O, Abdel-razeq H
Breast Cancer: Targets and Therapy 2026, 18:559555
Published Date: 9 April 2026
Peripheral Blood IL-6 and STAT3 Gene Expression as Biomarkers Associated with Neoadjuvant Chemotherapy Response in Triple-Negative Breast Cancer: A Prospective Cross-Sectional Study
Özdemir K, Muhtaroğlu A, Kamburoğlu MB, Guney Eskiler G, Özman Gökçe Z, Kocer B
Breast Cancer: Targets and Therapy 2026, 18:593138
Published Date: 8 April 2026
IFI44 Orchestrates an IL-10–Driven M2 Macrophage Program in Breast Cancer: An Immune Prognostic Signature
Wu J, Yi W, Liu M, Li Y, Zhou B, Wu Z, Cao W, Shi Q, Cai X, Xiong H
Breast Cancer: Targets and Therapy 2026, 18:579301
Published Date: 8 April 2026
Supportive Intervention for Unmet Needs Among Breast Cancer Patients and Their Spousal Caregivers: A Randomized Controlled Trial
Zhang Q, Wang S, Zhang J, Chu T, Chen X, Ma L, Zhou H, Wu Y, Xu D, Jiang K
Breast Cancer: Targets and Therapy 2026, 18:585827
Published Date: 8 April 2026
Discrimination of Triple-Negative Breast Cancer: A Robust Clinical Baseline versus Multimodal Magnetic Resonance Imaging Integrated Models with Assessment of Generalizability
Liao X, Wu X, Zheng J, Lin G, Lin D
Breast Cancer: Targets and Therapy 2026, 18:594356
Published Date: 2 April 2026
Lipid Metabolism and Breast Cancer Therapy: An Integrative Literature Review
Gong X, Zhang D, Wen Z, Zeng J, Tang Y, Deng J, Bin Y
Breast Cancer: Targets and Therapy 2026, 18:575419
Published Date: 1 April 2026
Prognostic Value of Ki-67 and Progesterone Receptor for Risk Stratification and Outcomes by Adjuvant Chemotherapy in Early Luminal-Type Breast Cancer
Chen HH, Chang SJ, Kan JY, Chen FM, Li CL, Takahashi H, Shih SL, Hou MF, Pan MR, Yang PF, Luo CW
Breast Cancer: Targets and Therapy 2026, 18:597707
Published Date: 1 April 2026
Health Related Quality of Life Among Women with Breast Cancer in Mogadishu, Somalia
Dirie AM, Ahmed NR, Dirie SA, Hassan SA, Abdi MA, Nour FE, Mohamed SA, Hassan KA, Dhiblawe SO, Fiidow OA, Jimale KA
Breast Cancer: Targets and Therapy 2026, 18:587275
Published Date: 27 March 2026
A Retrospective Analysis of a Serum Multi-Biomarker (CA153, TSGF, and CYFRA 21-1) Logistic Regression Model for Predicting Pathologic Complete Response to Neoadjuvant Chemotherapy in Breast Cancer
He L, Zhang W, Huang L, Lin X, Huang W
Breast Cancer: Targets and Therapy 2026, 18:567301
Published Date: 25 March 2026
Prognostic Significance of the CRP-Albumin-Lymphocyte Index (CALLY) in Triple Negative Breast Cancer Patients: A Real-World Retrospective Study
Liu Y, Zhang F, Guo C, Li Q
Breast Cancer: Targets and Therapy 2026, 18:582022
Published Date: 13 March 2026
Inhibition of MCCC2 Impedes TNBC Progression by Downregulating Leucine Metabolism-Dependent mTOR Signaling
Chi R, Zhang J, Li Z, Xie Y, Zheng Q, Chen J, Liu Y, Gong F
Breast Cancer: Targets and Therapy 2026, 18:579112
Published Date: 10 March 2026
Ovarian Escape in Hormone Receptor-Positive Breast Cancer: Mechanisms, Risk Factors, Clinical Consequences, and Management Strategies
Li Y, Wang W
Breast Cancer: Targets and Therapy 2026, 18:586408
Published Date: 10 March 2026
Development of a Prognostic Stratification Model and Identification of BDH1 as an Oncoprotein in Breast Cancer Based on Subcluster-Specific Markers of B-Cell Subsets
Kang S, Li Z, Lv C, Zhang F
Breast Cancer: Targets and Therapy 2026, 18:580906
Published Date: 10 March 2026
The Correlation Between CD8+ Tumor-Infiltrating Lymphocytes and the Efficacy of Neoadjuvant Therapy in Breast Cancer
Feng G, Zhong M, Xie D, Yuan X, Lu S, Zhu J, Gao S, Yi Z, Lin H, Zheng J, Zhou H, Wang Y
Breast Cancer: Targets and Therapy 2026, 18:533799
Published Date: 10 March 2026
SLAMF8 Promotes M2 Polarization of Macrophages and Enhances Breast Cancer Proliferation
Kong J, Tian R, Li S, Zang H, Cheng Y, Ni G, Liu W, Gong L
Breast Cancer: Targets and Therapy 2026, 18:560682
Published Date: 10 March 2026
Recent Advances and Emerging Directions in Machine Learning-Based Breast Cancer Drug Discovery: A Comprehensive Review
Cheng Y, Kong J, Liu X, Li S
Breast Cancer: Targets and Therapy 2026, 18:586786
Published Date: 9 March 2026
Efficacy and Safety of Neoadjuvant Stereotactic Body Radiotherapy (SBRT) Combined with Chemoimmunotherapy in Locally Advanced Breast Cancer: A Single-Center, Retrospective Pilot Study
Zhai M, Bi J, Ke Z, Hu M, Pi G, Li Y, He H, Li Y, Zheng H, Wu X, Verma V, Shao J, Han G
Breast Cancer: Targets and Therapy 2026, 18:577469
Published Date: 7 March 2026
A Brand-New Drainage Fluid Predictor, ICAM-1 for Implant Loss After the Immediate Reconstruction of Breast
He C, Jiang Y, Zhao R, Liu J, Yang H, Zhang R, Zhao Y
Breast Cancer: Targets and Therapy 2026, 18:585358
Published Date: 5 March 2026
Combined Treatment with Shuyu Pills and Everolimus Suppresses Triple-Negative Breast Cancer Growth via the PI3K/AKT/mTOR Pathway
Zhao J, Luo X, Li H, Cheng Y, Xie S, Lin X
Breast Cancer: Targets and Therapy 2026, 18:580570
Published Date: 4 March 2026
Drivers of Variation in the Rate of Radiotherapy Following Lumpectomy in the Military Health System
Ramos MLF, Zaorsky NG, Luan WP, Calo WA, Chetlen A, Lengerich EJ, Chi G, Segel JE
Breast Cancer: Targets and Therapy 2026, 18:555930
Published Date: 4 March 2026
Can We Adapt Neoadjuvant Rectal (NAR) Score with Systemic Immune-Inflammation Index (SII) and Prognostic Nutritional Index (PNI) as Prognostic Factors in Locally Advanced Breast Cancer?
Yüksel C, Doğan M, Çulcu S, Doğan L
Breast Cancer: Targets and Therapy 2026, 18:578298
Published Date: 20 February 2026
Novel Microbiome-Driven Approaches to Counteract Chemotherapy-Induced Mucositis in Breast Cancer Patients
Obeagu EI
Breast Cancer: Targets and Therapy 2026, 18:590718
Published Date: 19 February 2026
The Role of Actin-Binding Proteins in Breast Cancer Progression
Alfarafisa NM, Herriyanto RI, Alhaq KF, Fauzi MB, Khairani AF
Breast Cancer: Targets and Therapy 2026, 18:566309
Published Date: 19 February 2026
Clonal Dynamics and Molecular Heterogeneity of Metaplastic Breast Cancer: Focus on TP53 and PIK3CA Truncal Mutations
Ye R, Dai X, Yang Z, Zhang D, Hu Z, Liao Y, Yang Z
Breast Cancer: Targets and Therapy 2026, 18:558033
Published Date: 17 February 2026
Visceral and Subcutaneous Fat Deposits Exhibit Distinct Roles in the Initiation and Progression of Breast Cancer
Zhang Y, Li Q, Zhao L, Pang Y, Li L, Niu WW, Xing Y, Liu Y, Zhang FQ, Fan YC, Bao YY, Li CW, Yu K
Breast Cancer: Targets and Therapy 2026, 18:565061
Published Date: 16 February 2026
Identification of Potential Therapeutic Targets for Xihuang Pill in Breast Cancer: A Mendelian Randomization and Experimental Study
Tang Y, Yang Z, Ye Z, Su H, Zhu R, Meng X, Zheng Q
Breast Cancer: Targets and Therapy 2026, 18:572244
Published Date: 6 February 2026
Systemic Immune Remodeling in Breast Cancer: Selective Enrichment of TNFR2+ Circulating Lymphocytes in Breast Cancer
Absalan F, Azizi R, Hakimi H, Shariat M, Talei A, Sedghy F, Mehdipour F, Ghaderi A
Breast Cancer: Targets and Therapy 2026, 18:563472
Published Date: 5 February 2026
Identification and Validation of a Novel Theranostic Target in Triple Negative Breast Cancer with Transcriptomics and Protein Analyses
Lee H, Kim G, Kim M, Kim JL, Jung KH, Lee KH
Breast Cancer: Targets and Therapy 2026, 18:568001
Published Date: 4 February 2026
Challenging and Successful Therapy Decision-Making for AML Post Cytotoxic Therapy and Concomitant Active Breast Cancer – A Case Report and Experience-Driven Strategy
Wichtowski M, Adamska M, Łojko-Dankowska A, Gil L
Breast Cancer: Targets and Therapy 2026, 18:536327
Published Date: 30 January 2026
Keratin as a Potential Prognostic Biomarker for Breast Cancer Progression: An Evidence-Synthesizing Narrative Review
Khairani AF, Alhaq KF, Herriyanto RI, Fauzi MB, Alfarafisa NM
Breast Cancer: Targets and Therapy 2026, 18:578887
Published Date: 24 January 2026
Receptor Discordance and Molecular Subtype Changes in Visceral Metastases of Breast Cancer
Tian Z, Chen X, Li H, Li C, Qiu W, Wang X, Song X, Hou B, Liu Z, Yu J, Yu Z
Breast Cancer: Targets and Therapy 2026, 18:565375
Published Date: 23 January 2026
Clinical Value of Cardiac Troponin I in Assessing Anthracycline-Induced Cardiotoxicity in Postoperative Breast Cancer Patients
Li H, Li X, Tang S
Breast Cancer: Targets and Therapy 2026, 18:580515
Published Date: 23 January 2026
Development and Preliminary Validation of a Wearable Tumor Treating Fields Device for Breast Cancer Therapy
Lan Y, Zheng Y, Zhu Y, Xie X, Mou H, Jin W, Pan Y, Chen W, Zhang S, Chen G, Wang M
Breast Cancer: Targets and Therapy 2026, 18:568389
Published Date: 22 January 2026
Deep Learning Radiomics of Multiparametric MRI for Individualized Prediction of Axillary Lymph Node Response After Neoadjuvant Chemotherapy in Breast Cancer
Li S, Li R, Xu M, Liao J, Cao Z, Gong B, Yan F, Wang M, Tan H
Breast Cancer: Targets and Therapy 2026, 18:568337
Published Date: 21 January 2026
Identification of circRNA/lncRNA-miRNA-Transcription Factor-mRNA Networks to Identify Potential Biomarkers in Response to Neoadjuvant Therapy for Breast Cancer
Li D, Zhang Z, Chen Y, Zhao X, He K, Zhang R
Breast Cancer: Targets and Therapy 2026, 18:538948
Published Date: 17 January 2026
Endocrine Therapy versus Chemotherapy After CDK4/6 Inhibitor Progression in HR+/HER2- Metastatic Breast Cancer: A Multicenter Real-World Study from Turkey
Cangür C, Bülbül B, Yeğen IT, Ucun B, Eren Oö, Başaran H, Erdoğan AP, Şahin Hafızoğlu E, Gökmen E, Özkan O, Araz M, Oruç A, Yilmaz C, Gül G, Yildirim S
Breast Cancer: Targets and Therapy 2026, 18:571246
Published Date: 14 January 2026
Recent Advances in Antibody-Drug Conjugates and Immunotherapy Combinations for Treatment of Triple-Negative Breast Cancer
Chen H, Lu W, Zhou Y, Guo X, Wu S, Chen Y
Breast Cancer: Targets and Therapy 2026, 18:571054
Published Date: 14 January 2026
MLN51 (Metastatic Lymph Node Gene 51)/CASC3 (Cancer Susceptibility Candidate Gene 3), A Putative Tumour Suppressor in Breast Cancer, the Clinical and Therapeutic Connections
Cong B, Martin TA, Cao X, Ruge FS, Li AX, Mansel RE, Wang Y, Jiang WG
Breast Cancer: Targets and Therapy 2026, 18:565199
Published Date: 14 January 2026
Radiological and Histopathological Predictors of Survival in Neuroendocrine Differentiated Breast Cancer: A Comparative Analysis with NS-IDC
Çetin Tunçez H, Adibelli ZH, Havvat N, Kocatepe Çavdar D, Altın L, Bozer A
Breast Cancer: Targets and Therapy 2026, 18:569083
Published Date: 12 January 2026
Assessing Thrombotic Risk in Patients with HR+/HER2- Breast Cancer Receiving CDK4/6 Inhibitors: Insights from Real-World Data from the Middle East
Alsuhebany N, Alanazi A, Alzahrani MY, Alyousef S, Aldawish BS, Aljardan S, Abu Alnasr R, Althumali IM, AlDoughaim M, Alfehaid L, Refae S, Abdelhafiez Jnr NA, Bakhribah H, Alqahtani T
Breast Cancer: Targets and Therapy 2026, 18:554024
Published Date: 10 January 2026
The Novel ROCK Inhibitor Fasudil Derivative Fasudil-D-6h Prevents Tumour Progression by Regulating the Adherens Junction Signalling Pathway in Triple-Negative Breast Cancer
Liang J, Tang M, Wang L
Breast Cancer: Targets and Therapy 2026, 18:547003
Published Date: 8 January 2026
Emerging Targeted and Multimodal Therapeutic Strategies in Breast Cancer: A Comprehensive Review
Wu W, He Y, Zhang C
Breast Cancer: Targets and Therapy 2026, 18:575936
Published Date: 7 January 2026