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Elevate Journal

Cancer Management and Research

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ISSN: 1179-1322

Journal Articles:

CAR-T Cell Therapy for Cancer: Past, Present and Future of a Game-Changing Treatment

Since the 2017 US FDA approval of the use of anti-CD19 CAR-T cell therapy for use against B-cell malignancies, CAR-T therapy has demonstrated significant clinical benefits in treating hematologic malignancies, showing clinical efficacy and durability even in patients who have been refractory to other treatments. Research is underway to develop and evaluate CAR-based therapies for application in solid tumors.