Back to Journals » Cancer Management and Research » Targeting Cancer Stem Cells to Overcome Therapy Resistance: Mechanisms, Biomarkers, and Clinical Translation
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Cancer Management and Research
ISSN: 1179-1322
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Journal Articles:
- Self Screening for Cancer: Promises and Pitfalls (1)
- Immune Effector Cells for Cancer Therapy – CAR-T and beyond (1)
- Defining Genetic Contributors to Cancer Risk (1)
- The Cancer Treatment Revolution and the Threat to Equitable Global Medicines Access (2)
- Establishing New Standards in Neuroendocrine Tumors: Raising the Bar to Set New Benchmarks (1)
Targeting Cancer Stem Cells to Overcome Therapy Resistance: Mechanisms, Biomarkers, and Clinical Translation
Cancer stem cells (CSCs) are a therapy-resistant subpopulation that drives tumor initiation, progression, metastasis, and recurrence. Their capacity for self-renewal, plasticity, and adaptation underpins resistance to chemotherapy, radiotherapy, and immunotherapy, making them a central obstacle to long-term therapeutic success. Eradicating CSCs is thus recognized as a critical goal in improving long-term patient survival.