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Cancer Management and Research

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ISSN: 1179-1322

Archive: Volume 18, 2026

Advances in Phase III Clinical Trials and Future Challenges of Targeted Therapy in Advanced Ovarian Cancer

Zhang L, Qiao R, Chen M, Yang Z, Gong M, Yu R

Cancer Management and Research 2026, 18:603916

Published Date: 12 May 2026

A Qualitative Study on the Psychological Experience of Lung Cancer Patients During the Perioperative Period

Lei XN, Wang Q, Yan LC, Lu L, Xiao YS, Yang LY, Guo YH

Cancer Management and Research 2026, 18:589437

Published Date: 8 May 2026

Hyperbaric Oxygen Reverses High-Glucose–Induced Stemness and Radioresistance in Non-Small Cell Lung Cancer Cells

Lee JY, Chung CL, Tseng TT, Kuo SH, Liu YP, Wu MT, Tsai HP, Kwan AL

Cancer Management and Research 2026, 18:611017

Published Date: 6 May 2026

Analysis of Causes and Risk Factors for Deaths Among Pediatric Oncology Patients: A 20-Year Observation

Mitura-Lesiuk M, Dubaj M, Drabko K, Zawitkowska J

Cancer Management and Research 2026, 18:604728

Published Date: 5 May 2026

Resection Rates and Predictors of Resectability of Pancreatic Tumors at Mulago Hospital: A Retrospective Cross-Sectional Study

Kikuba G, Kasagga B, Ssempebwa P, Kituuka O, Okeny P

Cancer Management and Research 2026, 18:594797

Published Date: 5 May 2026

Relationship Between Netrin-1 Staining and Neoadjuvant Treatment Response in HER2-Positive Locally Advanced Breast Cancer [Corrigendum]

Gülbağcı B, Çakırsoy Çakar G, Küçükarda A, Çavdar E, Hacıbekiroğlu I

Cancer Management and Research 2026, 18:620903

Published Date: 30 April 2026

Transarterial Chemoembolization Combined with Regorafenib and PD-1 Inhibitor as Second-Line Therapy for Unresectable Hepatocellular Carcinoma

Wang D, Zhang W, Gao X, Kong H, Zhang H, Huang J, Zhang M, Chang X, Zeng Z

Cancer Management and Research 2026, 18:578610

Published Date: 29 April 2026

Multimodal Fusion of 3D CT and Pathological Images for Gastric Cancer Recurrence Prediction

Cao L, Tian M, Li J, Chen Z, Wang X, Zhong S, Wu G, Tang Z, Yu J

Cancer Management and Research 2026, 18:563640

Published Date: 27 April 2026

Facilitators and Barriers to Cervical Cancer Screening Among Women in a Rural District of Northeastern Uganda, a Qualitative Study

Mutyaba I, Akurut H, Nabaasa R, Limo J, Okupa E, Omuke CA, Opito R

Cancer Management and Research 2026, 18:598738

Published Date: 23 April 2026

Perioperative FLOT versus Definitive 50.4 Gy Chemoradiotherapy in Siewert II Esophagogastric Junction Adenocarcinoma: A Multicenter Retrospective Cohort Study

Dinc Sonusen S, Sucuoglu Isleyen Z, Aydin O, Erciyestepe M, Sakin A, Gurdal N, Urun M, Mermit Ercek B, Bilici M, Gurbuz HS, Gunenc S, Akyel R, Celik E, Erturk K, Atci MM

Cancer Management and Research 2026, 18:583473

Published Date: 20 April 2026

Oncolytic Vaccinia Virus-Engineered EVs Convert Tumor-Promoting Macrophages into Anti-Tumor Effectors

Chen L, Ye L, Bao L, Wang J, Tan M

Cancer Management and Research 2026, 18:589766

Published Date: 20 April 2026

Digital Health in Pediatric Oncology and Hematooncology: A Quasi-Systematic Review of Telehealth, mHealth and Precision Medicine

Ziętara KJ, Pawłowski P, Zaj N, Banasik M, Samardakiewicz M

Cancer Management and Research 2026, 18:570990

Published Date: 17 April 2026

Context-Dependent Dual Roles of the Plexin-B Family in Cancer Progression: Mechanisms and Therapeutic Implications

Mao X, Lin W, Zhang X, Yang M, Shen J, Liang H, Song J, Meng L, Long F, Wang T, Li Y

Cancer Management and Research 2026, 18:593922

Published Date: 13 April 2026

Burden of Care: Stress, Anxiety, Depression, and Quality of Life in Cancer Caregivers in Kuwait: A Cross-Sectional Study

Alhamad H, Alenezi A, Shabakoh H, Alshammari A, Alnaser MZ

Cancer Management and Research 2026, 18:582023

Published Date: 2 April 2026

Apolipoprotein E (APOE) Promotes Cell Proliferation and Invasion in Glioma via the PI3K/AKT Signaling Pathway

Xia M, Chen K, Chen W, Ren Z, Li X

Cancer Management and Research 2026, 18:594906

Published Date: 1 April 2026

Development and Validation of a Traditional Chinese Medicine Constitution-Based Risk Score for Advanced Colorectal Neoplasia in Asymptomatic Chinese Adults

Huang C, Hou Y, Liu QH, Kang Q, Fan YJ, Zhu LQ, Sun L, Men RC, Li XY, Gu YL, Ni Q, Wang H, He Y

Cancer Management and Research 2026, 18:568884

Published Date: 31 March 2026

Improving Non-Invasive Prediction of Thyroid Nodule Malignancy: A Machine Learning-Based Clinical Approach

Reiner M, Drobińska H, Miciak M, Kisiel M, Biernat S, Kaliszewski K

Cancer Management and Research 2026, 18:571308

Published Date: 28 March 2026

Integrating Ultrasound and Clinicopathologic Characteristics to Predict the Invasive Papillary Thyroid Carcinoma Among Indeterminate Thyroid Nodules

Yao M, Zhang Z, Hua Z, Chen Y, Zhao S, Sun Y, Shen J, Zhang X

Cancer Management and Research 2026, 18:577043

Published Date: 28 March 2026

Correlates of the Stage of Esophageal Cancer at Diagnosis Among Patients: A Mixed-Methods Cross-Sectional Study

Nagujja F, Tamwesigire IK, Natuhwera G

Cancer Management and Research 2026, 18:519394

Published Date: 25 March 2026

Incidence and Risk Factors of Chemotherapy-Induced Hepatotoxicity: A Cross-Sectional Study

Joel S, Bukke SPN, Mamilla Mugaiahgari BK, Kyomya J, Idrine KK, Godwin N, Muasya PK, Abdi AA, Makuza KR, Tumwebaza JM, Narapureddy BR, Goruntla N, Mwandah DC, Shogar AE, Abdalla SA, Isiiko J, Yadesa TM

Cancer Management and Research 2026, 18:589840

Published Date: 25 March 2026

Establishment of Predictive Models for Second Hepatoma Recurrence

Su M, Zhong W, Chen Z, Zhang G

Cancer Management and Research 2026, 18:566522

Published Date: 24 March 2026

Addressing the Neglected Burden of Cancer Cachexia: A Quasi-Experimental Study at Uganda Cancer Institute

Dave D, Angucia BS, Komukama C, Kahwa A, Srikant S, Pakileto A, Anecho E, Niyonzima N

Cancer Management and Research 2026, 18:576718

Published Date: 24 March 2026

Effectiveness of Neck Lymph Node Dissection for Breast Cancer Patients with Isolated Supraclavicular Nodal Recurrence

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Isozaki H, Yamamoto Y, Murakami S, Matsumoto S, Takama T, Isozaki Y

Cancer Management and Research 2026, 18:573339

Published Date: 19 March 2026

Circulating Tumor Cell PD-L1 and Peripheral Blood CD8+ T-Cell PD-1 as Dual Liquid Biopsy Biomarkers for Immunotherapy Outcomes in Advanced Non–Small Cell Lung Cancer: A Retrospective Study

Guan S, Huangfu J, Zhu X, Ge Y, Ding Y, Chen T, Zhang Y, Yang T, Liu H, Zhang L, Chen X, Zhou J

Cancer Management and Research 2026, 18:580857

Published Date: 18 March 2026

Evaluation of DNA Methylation in TAC1, SOX17, and RASSF1A for the Early Diagnosis of Lung Cancer

Wang H, Zhang T, Li L, Lin F, Yuan X, Wang J, Xu J, Xu H, Zhou F, Luo W, Chen Z

Cancer Management and Research 2026, 18:573663

Published Date: 17 March 2026

Deficient Mismatch Repair Subtypes in Vietnamese Colorectal Cancer: Clinicopathologic Associations, Predictive Modeling, and IHC-PCR Concordance

Trinh HD, Pham QT, Phong NH, Huong Ly TT, Ho QC, Vu HA, Kha VV, Ngo QD

Cancer Management and Research 2026, 18:587649

Published Date: 17 March 2026

Preoperative Prognostic Nutritional Index Predicts Postoperative Outcomes in Colorectal Cancer: A Propensity Score-Matched Cohort Study

Kor CT, Tsai TJ, Chuang T, Chang JS, Chen WH, Chen CW, Wu YH, Liu YS, Huang XY, Chang YY

Cancer Management and Research 2026, 18:558639

Published Date: 17 March 2026

Correlation Analysis Between Circulating Tumor DNA and Prognosis in Patients with Hepatocellular Carcinoma

Ma X, Yuan W, Liu S, Ren Q, Lin Z

Cancer Management and Research 2026, 18:573159

Published Date: 13 March 2026

Inhibition of CDK1 Promotes Immunogenic Cell Death in Neuroblastoma

Li Y, Lan T, Liang R, Liu L

Cancer Management and Research 2026, 18:569214

Published Date: 10 March 2026

High Efficacy of Chemoimmunotherapy in Advanced ALK-Rearranged Lung Squamous Cell Carcinoma: A Case Report

Niu Y, Ding B, Shi J, Yang Y, Zhao J, Wang D

Cancer Management and Research 2026, 18:591554

Published Date: 7 March 2026

Impact of Surgical Wait Time on Survival After Radical Cystectomy for Muscle-Invasive Bladder Cancer: A Retrospective Cohort Study

Wang Q, Pei CS, Cao JY, Peng H, Niu W, Chang PA, Yao W, Zhang GH, Zhou J, Li SS, Wu JC, Wang H, Ju WB, Wang QC

Cancer Management and Research 2026, 18:583762

Published Date: 5 March 2026

Development and Internal Validation of a Nomogram for Predicting Recurrence in Endometrial Cancer Based on Pathological and Histological Indicators

Miao M, Huang B, Jiang Y, Hua Y, Guo F, Liu Q, Ding L, Zhou H

Cancer Management and Research 2026, 18:600578

Published Date: 4 March 2026

Impact of Ethnic Differences and HER2 Protein Expression on the Age at Breast Cancer Diagnosis: A Mixed Methods Study

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Karutjaiva MS, Aboua YG, Omoruyi BE, Shafodino F, Chambuso R, Mwapagha LM, Okudoh VI

Cancer Management and Research 2026, 18:529863

Published Date: 4 March 2026

Ginseng-Derived Exosomes Attenuate Immune Evasion in NSCLC via PD-L1 Modulation [Corrigendum]

Zhu LJ, Chen XQ, Lin QY, Feng JN, Yuan SF

Cancer Management and Research 2026, 18:590886

Published Date: 2 March 2026

Dual Role of AITD in TgAb-Positive PTC: Delayed Antibody Clearance with Enhanced RAIT Response

Ge H, Chen S, Song L, Lin Z, Li Y, Chen W

Cancer Management and Research 2026, 18:573414

Published Date: 24 February 2026

Identifying of Ubiquitin-Fold Modifier 1 as a Potential Prognostic Biomarker for Unresectable Pancreatic Cancer by Proteomics Analysis

Wang J, Xu K, Xu L, Geng J, Liu C, Gu X, Li X

Cancer Management and Research 2026, 18:573143

Published Date: 24 February 2026

Hypertriglyceridemia During Anticancer Therapy in Pediatric Patients with Acute Lymphoblastic Leukemia – A Nationwide Experience

Zawitkowska J, Latoch E, Karska K, Drabko K, Lejman M, Paczóska KE, Ociepa T, Malecka A, Sęga-Pondel D, Kalwak K, Konończuk K, Kołodrubiec J, Trelińska J, Demidowicz E, Andrzejewska M, Derwich K, Zakrzewska Z, Skoczeń S, Mizia-Malarz A, Karolczyk G, Bal W, Chaber R, Tyszka P, Badowska W, Janiszewska M, Kowalczyk J, Młynarski W, Szczepański T, Styczyński J, Irga-Jaworska N, Muszyńska-Rosłan K

Cancer Management and Research 2026, 18:572651

Published Date: 21 February 2026

A Multiphase CT-Based Radiomics-Clinical Model to Identify Inadequate Future Liver Remnant Hypertrophy After Portal Vein Embolization Before Major Hepatectomy

Zhou R, Liu D, Huang J, Liu F, Zhou W, Zou M, Wu X, Liu H, Jia N

Cancer Management and Research 2026, 18:573304

Published Date: 17 February 2026

CAR-T Cell Therapy in Glioblastoma: Overcoming Immunological Barriers and Advancing Clinical Translation

Pourmasoumi P, Pourmasoumi A, Zamani F, Amini A, Shokri S

Cancer Management and Research 2026, 18:580320

Published Date: 17 February 2026

Clinicopathological and Genomic Analysis of SMARCA4-Deficient Non-Small Cell Lung Cancer: A Retrospective Cohort Study

Chen D, Zhang H, Wang D, Ye W, Zhao H, Zhang C, Wu S, Shi Q

Cancer Management and Research 2026, 18:565394

Published Date: 17 February 2026

A Pharmacogenomic Basis for Tolerance of 5-Fluorouracil Following Early, Severe Toxicity from Capecitabine in a CDA Ultrarapid Metabolizer Colon Cancer Patient: A Case Report

Mazhindu TA, Chikwambi Z, Matsikidze E, Grimes KV, Borok MZ, Ndlovu N, Masimirembwa C

Cancer Management and Research 2026, 18:571794

Published Date: 14 February 2026

Relationship Between Netrin-1 Staining and Neoadjuvant Treatment Response in HER2-Positive Locally Advanced Breast Cancer

Gülbağcı B, Çakırsoy Çakar G, Küçükarda A, Çavdar E, Hacıbekiroğlu I

Cancer Management and Research 2026, 18:551516

Published Date: 11 February 2026

Circulating Tumor DNA in Cholangiocarcinoma: A Precision Oncology Roadmap

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Wei H, Wang J, Wu Q, Qin M

Cancer Management and Research 2026, 18:574678

Published Date: 6 February 2026

Clinicopathological Features and Prognostic Differences Between Primary and Relapsed or Refractory Extramedullary Multiple Myeloma

Hu X, Yang M, Qi Y, Dai X, Zhou J, Li Y, Zhao H, Li X, Jin M

Cancer Management and Research 2026, 18:552024

Published Date: 5 February 2026

Haploidentical Allogeneic Cell Transplantation in Relapsed/Refractory Multiple Myeloma

Frimmel J, Morgner A, Brogsitter C, Trautmann-Grill K, Kunadt D, Teipel R, Röllig C, Hänel M, Schetelig J, Stölzel F, Bornhäuser M

Cancer Management and Research 2026, 18:564588

Published Date: 4 February 2026

Non-Invasive Techniques for Early Detection of Oral Squamous Cell Carcinoma: A Narrative Review

Yang J, Yuan Z, Mei S, Liu H, Xiang Q, Song E

Cancer Management and Research 2026, 18:569352

Published Date: 4 February 2026

Adaptation of MALDI-TOF MS Technique for Tracking Changes in the Urinary Microbiome During and After Radiotherapy for Prostate Cancer

Złoch M, Sibińska E, Monedeiro F, Miśta W, Arendowski A, Fijałkowski P, Pietrowska M, Mrochem-Kwarciak J, Jędrzejewska A, Telka E, Karoń K, Rabsztyn M, Pomastowski P, Gabryś D

Cancer Management and Research 2026, 18:573379

Published Date: 4 February 2026

Elaeagnus Angustifolia: Unveiling Anti-Cancer Potential from Ancient Remedies to Modern Therapeutics

Zakaria ZZ, Ahen YMA, Ahmed NH, Sokary S, Abu-hijleh H, Bawadi H, Al-Asmakh M

Cancer Management and Research 2026, 18:521703

Published Date: 27 January 2026

Research Progress on Copper Metabolism, Cuprotosis, and Their Regulatory Mechanism in Tumor Diagnosis and Treatment

Wang R, Wang F, Xu Y, Sun W, Jiang P, Guo Y, Yu QQ

Cancer Management and Research 2026, 18:546059

Published Date: 22 January 2026

Saikosaponin D Induced Apoptosis and Anti-Tumor Effect Enhancing Chemotherapy Sensitivity of Gemcitabine in Patient-Derived Cholangiocarcinoma Organoids

Han B, Xing G, Du K, Li Y, Liu M, Zheng J, Wang S, Li C, Zhang S, Zhang C, Liu X, Shao Z, Wu W

Cancer Management and Research 2026, 18:564565

Published Date: 22 January 2026

Prognostic Impact of Cetuximab-Related Hypomagnesemia and Hypokalemia in RAS/RAF Wild-Type Colorectal Cancer: A Multicenter Study

Güzel HG, Kıvrak Salim D, Ulukal Karancı E, Acun M, Çatlı MM, Mordağ Çiçek C, Karaman Y, Kaya BE, Terzi A, Köseoğlu Ç, Kahraman EG, Gököz Doğu G, Şahin AB, Karakurt Eryılmaz M, Atağ E, Akay S, Öztürk B

Cancer Management and Research 2026, 18:570548

Published Date: 21 January 2026

Biological Mechanisms of Microwave Ablation in Thyroid Tumors and Its Induced Immunomodulatory Effects

Wang Z, Dai Q, Yan S, Sun X, Wang G, He Z, He Y, Wang Z, Wang L, Liu C, Liu T, Gao R, Zhao P, Wang K

Cancer Management and Research 2026, 18:575901

Published Date: 17 January 2026

Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Nasopharyngeal Carcinoma in Non-Endemic Regions: A Single-Arm Phase 2 Clinical Trial

Zhou L, Tao Z, Zhou Y, Yang L, Zhang Y, He J, Sun B, Wang R, Yang J, Gao J

Cancer Management and Research 2026, 18:559229

Published Date: 15 January 2026

Complementary and Alternative Therapy Use Among Cancer Patients in Qassim: Patterns, Predictors, and Patient Perspectives

Alshamsan B, Alharbi LA, Alshudukhi RI, Alaql FA, Alsweed R, Alodhaybi N

Cancer Management and Research 2026, 18:569861

Published Date: 14 January 2026

Taxanes Versus Pemetrexed After Osimertinib Resistance in EGFR-Mutated NSCLC: A Retrospective Cohort with Two-Model In Vitro Validation

Yang N, Wan N, Guo Y, Xiong L, Chen X, Du D, Xie B, Zhou J

Cancer Management and Research 2026, 18:564913

Published Date: 13 January 2026

Advancing Precision Medicine in Non-Small Cell Lung Cancer Diagnostics in a Southeast Asian Country

Poh ME, Thiagarajan M, Tho LM, Ho GF, Mohammad N, Tan WC, How SH

Cancer Management and Research 2026, 18:570997

Published Date: 13 January 2026

Molecular Actions of Cyclophosphamide (CPA) in the Ovaries of Rats with Mammary Neoplasia

Nynca A, Swigonska S, Molcan T, Petroff BK, Ciereszko RE

Cancer Management and Research 2026, 18:557751

Published Date: 9 January 2026

Parameters That May Predict NAC Effectiveness in Hormone-Positive Breast Cancer According to CPS Score

Buyukbayram ME, Hannarici Z, Turhan A, Çağlar AA, Çoban Eşdur P, Bilici M, Tekin SB, Dinar Ayman C

Cancer Management and Research 2026, 18:569515

Published Date: 8 January 2026

Vitamin D Receptor in Cancer: Biological Functions, Mechanistic Insights, and Clinical Relevance

Liang M, Yin S, Dai Y, Xu F, Chang B, Volarević S, Li X, Wu D, Li Z, Wang T

Cancer Management and Research 2026, 18:571200

Published Date: 8 January 2026

Perioperative Body Image Trajectories in Amputation Patients with Malignant Bone Tumors: A Latent Transition Analysis

Li R, Wang Y, Mu D, Song H, Li YF, Zhao H

Cancer Management and Research 2026, 18:573128

Published Date: 7 January 2026

Primary Mucosal Routes of Opioid Administration for Treating Terminal Cancer Pain: Rectal, Buccal, and Intranasal Delivery

Huang XY, Qi Q, Zhang CS, Huang K, Liu X, Deng XJ, Chen L

Cancer Management and Research 2026, 18:564282

Published Date: 6 January 2026