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Drug Design, Development and Therapy

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ISSN: 1177-8881

Journal Articles:

Structure-Based Virtual Screening of New Skp1 Inhibitor Chemotypes Targeting F-Box Binding Interface

Hussain M, Lu Y, Wang GZ, Tariq M, Zhang J, Zhou GB, Liu J

Drug Design, Development and Therapy 2026, 20:578211

Published Date: 30 March 2026

Drug Polymer Nanoparticles: An Advancement in Biomedical Solutions and Targeted Drug Delivery

Rananaware P, Narayan M, Brahmkhatri V

Drug Design, Development and Therapy 2026, 20:562785

Published Date: 23 February 2026

Fragment Based Drug Discovery by Microscale Thermophoresis Targeting Klebsiella pneumoniae and Escherichia coli IspE

Walsh DJ, Willocx D, Hamid R, Hamed MM, Hirsch AKH

Drug Design, Development and Therapy 2025, 19:11345-11353

Published Date: 18 December 2025

Detailed in silico Evaluation of WNV Proteins: Dynamic and Thermodynamic Insights into Doravirine as a Potential Multitarget Agent

Curcio A, Torti C, Quiros-Roldan E, Alcaro S, Artese A

Drug Design, Development and Therapy 2025, 19:11021-11043

Published Date: 12 December 2025

SNAr Reactive Pyrazine Derivatives as p53-Y220C Cleft Binders with Diverse Binding Modes

Klett T, Stahlecker J, Schwer M, Jaag SJ, Masberg B, Knappe C, Lämmerhofer M, Stehle T, Boeckler FM

Drug Design, Development and Therapy 2025, 19:4727-4753

Published Date: 3 June 2025

Rho Kinase Inhibitors in Glaucoma Management: Current Perspectives and Future Directions

Chatzimichail E, Christodoulaki E, Konstas PAG, Tsiropoulos GN, Amaxilati E, Gugleta K, Gatzioufas Z, Panos GD

Drug Design, Development and Therapy 2025, 19:2519-2531

Published Date: 2 April 2025

Screening of Covalent Kinase Inhibitors Yields Hits for Cysteine Protease USP7 / HAUSP

Ernst LN, Jaag SJ, Wydra VR, Masberg B, Knappe C, Gerstenecker S, Serafim RAM, Liang XJ, Seidler NJ, Lämmerhofer M, Gehringer M, Boeckler FM

Drug Design, Development and Therapy 2025, 19:2253-2284

Published Date: 25 March 2025

Bimatoprost Intracameral Implant (Durysta®): A New Era in Glaucoma Management Through Sustained-Release Innovation

Vagiakis I, Papadopoulou EP, Amaxilati E, Tsiropoulos GN, Konstas AG, Panos GD

Drug Design, Development and Therapy 2025, 19:703-714

Published Date: 31 January 2025

Effects of Dexamethasone Intravitreal Implant on Multifocal Electroretinography in Diabetic Macular Oedema

Tranos P, Koukoula S, de Politis PB, Tranou M, Giamouridou O, Stavrakas P, Panos GD

Drug Design, Development and Therapy 2024, 18:5367-5375

Published Date: 25 November 2024

Copolymerized Polymers Based on Cyclodextrins and Cationic Groups Enhance Therapeutic Effect of Rebamipide in the N-Acetylcysteine-Treated Dry Eye Model

Otake H, Kobayashi K, Kadowaki R, Kosaka T, Itahashi M, Tsubaki M, Matsuda M, Iwakiri N, Harata E, Nagai N

Drug Design, Development and Therapy 2024, 18:4345-4358

Published Date: 27 September 2024

Revisiting Niclosamide Formulation Approaches – a Pathway Toward Drug Repositioning

Jug M, Laffleur F, Millotti G

Drug Design, Development and Therapy 2024, 18:4153-4182

Published Date: 17 September 2024

Evaluation of a Covalent Library of Diverse Warheads (CovLib) Binding to JNK3, USP7, or p53

Klett T, Schwer M, Ernst LN, Engelhardt MU, Jaag SJ, Masberg B, Knappe C, Lämmerhofer M, Gehringer M, Boeckler FM

Drug Design, Development and Therapy 2024, 18:2653-2679

Published Date: 1 July 2024

Development and Characterization of a Novel Carbon-11 Labeled Positron Emission Tomography Radiotracer for Neuroimaging of Sirtuin 1 with Benzoxazine-Based Compounds

Wang Y, Liu Y, Wang Y, Bai P, Hallisey MR, Varela BL, Siewko A, Wang C, Xu Y

Drug Design, Development and Therapy 2024, 18:819-827

Published Date: 15 March 2024

A Window for Enhanced Oral Delivery of Therapeutics via Lipid Nanoparticles

Amekyeh H, Sabra R, Billa N

Drug Design, Development and Therapy 2024, 18:613-630

Published Date: 29 February 2024

Ranibizumab Biosimilars in Treating Retinal Disorders: A Cost-Effective Revolution?

Chatzimichail E, Pfau K, Gatzioufas Z, Panos GD

Drug Design, Development and Therapy 2024, 18:365-374

Published Date: 8 February 2024

The Role of Rho Kinase Inhibitors in Corneal Diseases

Futterknecht S, Chatzimichail E, Gugleta K, Panos GD, Gatzioufas Z

Drug Design, Development and Therapy 2024, 18:97-108

Published Date: 19 January 2024

Faricimab: Transforming the Future of Macular Diseases Treatment - A Comprehensive Review of Clinical Studies

Panos GD, Lakshmanan A, Dadoukis P, Ripa M, Motta L, Amoaku WM

Drug Design, Development and Therapy 2023, 17:2861-2873

Published Date: 18 September 2023

Intravitreal Fluocinolone Acetonide Implant (ILUVIEN®) for the Treatment of Retinal Conditions. A Review of Clinical Studies

Mushtaq Y, Mushtaq MM, Gatzioufas Z, Ripa M, Motta L, Panos GD

Drug Design, Development and Therapy 2023, 17:961-975

Published Date: 30 March 2023

Brolucizumab for the Treatment of Degenerative Macular Conditions: A Review of Clinical Studies

Karasavvidou EM, Tranos P, Panos GD

Drug Design, Development and Therapy 2022, 16:2659-2680

Published Date: 9 August 2022

Care pathways and treatment patterns for patients with heart failure in China: results from a cross-sectional survey

Jackson JDS, Cotton SE, Bruce Wirta S, Proenca CC, Zhang M, Lahoz R, Balas B, Calado FJ

Drug Design, Development and Therapy 2018, 12:2311-2321

Published Date: 26 July 2018

Burden of heart failure on caregivers in China: results from a cross-sectional survey

Jackson JDS, Cotton SE, Bruce Wirta S, Proenca CC, Zhang M, Lahoz R, Calado FJ

Drug Design, Development and Therapy 2018, 12:1669-1678

Published Date: 8 June 2018

Burden of heart failure on patients from China: results from a cross-sectional survey

Jackson JDS, Cotton SE, Bruce Wirta S, Proenca CC, Zhang M, Lahoz R, Calado FJ

Drug Design, Development and Therapy 2018, 12:1659-1668

Published Date: 8 June 2018

Ten years of clinical experience with biosimilar human growth hormone: a review of safety data

Borrás Pérez MV, Kriström B, Romer T, Walczak M, Höbel N, Zabransky M

Drug Design, Development and Therapy 2017, 11:1497-1503

Published Date: 16 May 2017

Ten years' clinical experience with biosimilar human growth hormone: a review of efficacy data

López-Siguero JP, Pfäffle R, Chanson P, Szalecki M, Höbel N, Zabransky M

Drug Design, Development and Therapy 2017, 11:1489-1495

Published Date: 16 May 2017

Ten years of biosimilars in Europe: development and evolution of the regulatory pathways

Schiestl M, Zabransky M, Sörgel F

Drug Design, Development and Therapy 2017, 11:1509-1515

Published Date: 16 May 2017