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Drug Design, Development and Therapy
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Journal Articles:
- Modern Computational Approaches for Drug Design and Discovery (3)
- Advances in p53 Drug Discovery (4)
- Nanotechnology in Drug Delivery for Neurodegenerative Diseases (2)
- New Trends in Formulations for Oral Inhalation (1)
- Exploring Fragment-Based Approaches in Drug Discovery (2)
- Advances in design and development of ophthalmic drugs (9)
- Using Innovative Drug Delivery Systems to Improve the Efficacy and Applicability of Poorly Water-soluble Drugs (4)
- Beyond Brain Boundaries: Overcoming the Blood-Brain Barrier to Reach the Central Nervous System (1)
- A cross-sectional survey on heart failure from China: disease burden and management (3)
- Ten Years of Biosimilars in Europe (4)
Advances in design and development of ophthalmic drugs
Ophthalmic diseases, including glaucoma, age-related macular degeneration, diabetic retinopathy, and dry eye disease, are a significant public health concern, affecting millions of people worldwide. Despite the increasing availability of some effective treatments, there is still an unmet need for safe and even more effective drugs that can treat these conditions. This Article Collection brings together leading researchers and clinicians in the field to present their latest research on the design and development of ophthalmic drugs.
The Role of Rho Kinase Inhibitors in Corneal Diseases
Futterknecht S, Chatzimichail E, Gugleta K, Panos GD, Gatzioufas Z
Drug Design, Development and Therapy 2024, 18:97-108
Published Date: 19 January 2024
Ranibizumab Biosimilars in Treating Retinal Disorders: A Cost-Effective Revolution?
Chatzimichail E, Pfau K, Gatzioufas Z, Panos GD
Drug Design, Development and Therapy 2024, 18:365-374
Published Date: 8 February 2024
Bimatoprost Intracameral Implant (Durysta®): A New Era in Glaucoma Management Through Sustained-Release Innovation
Vagiakis I, Papadopoulou EP, Amaxilati E, Tsiropoulos GN, Konstas AG, Panos GD
Drug Design, Development and Therapy 2025, 19:703-714
Published Date: 31 January 2025
Intravitreal Fluocinolone Acetonide Implant (ILUVIEN®) for the Treatment of Retinal Conditions. A Review of Clinical Studies
Mushtaq Y, Mushtaq MM, Gatzioufas Z, Ripa M, Motta L, Panos GD
Drug Design, Development and Therapy 2023, 17:961-975
Published Date: 30 March 2023
Rho Kinase Inhibitors in Glaucoma Management: Current Perspectives and Future Directions
Chatzimichail E, Christodoulaki E, Konstas PAG, Tsiropoulos GN, Amaxilati E, Gugleta K, Gatzioufas Z, Panos GD
Drug Design, Development and Therapy 2025, 19:2519-2531
Published Date: 2 April 2025
Brolucizumab for the Treatment of Degenerative Macular Conditions: A Review of Clinical Studies
Karasavvidou EM, Tranos P, Panos GD
Drug Design, Development and Therapy 2022, 16:2659-2680
Published Date: 9 August 2022
Faricimab: Transforming the Future of Macular Diseases Treatment - A Comprehensive Review of Clinical Studies
Panos GD, Lakshmanan A, Dadoukis P, Ripa M, Motta L, Amoaku WM
Drug Design, Development and Therapy 2023, 17:2861-2873
Published Date: 18 September 2023
Copolymerized Polymers Based on Cyclodextrins and Cationic Groups Enhance Therapeutic Effect of Rebamipide in the N-Acetylcysteine-Treated Dry Eye Model
Otake H, Kobayashi K, Kadowaki R, Kosaka T, Itahashi M, Tsubaki M, Matsuda M, Iwakiri N, Harata E, Nagai N
Drug Design, Development and Therapy 2024, 18:4345-4358
Published Date: 27 September 2024
Effects of Dexamethasone Intravitreal Implant on Multifocal Electroretinography in Diabetic Macular Oedema
Tranos P, Koukoula S, de Politis PB, Tranou M, Giamouridou O, Stavrakas P, Panos GD
Drug Design, Development and Therapy 2024, 18:5367-5375
Published Date: 25 November 2024