Prommahom A, Balit T, Somkana S, Manprasong S, Panyasuppakun C, Kijkraikul A, Thawornrungroaj P, Thawornrungroaj P, Dharmasaroja P, Gonmanee T, Khemawoot P, Khwanraj K

Journal of Experimental Pharmacology 2025, 17:687-705

Published Date: 1 October 2025

Original Research

Antihypertensive Effects of Diosmetin in Hypertension-Induced Cardiovascular Abnormalities in Rats

Jan-O B, Iampanichakul M, Potue P, Khamseekaew J, Pakdeechote P, Pocasap P, Prachaney P, Poasakate A, Maneesai P

Journal of Experimental Pharmacology 2025, 17:667-685

Published Date: 29 September 2025

Review

Diabetic Peripheral Neuropathy: Pathophysiology and New Insights into the Mechanism of Action of High-Concentration Topical Capsaicin

Armstrong DG, Bley K, Simpson DM, Staats P, Allen S, Carnevale A, Marcondes L

Journal of Experimental Pharmacology 2025, 17:651-665

Published Date: 9 September 2025

Original Research

Psidium guajava Leaves n-Hexane Fraction Antibacterial Activity and the Inhibition of Gene Expression of gtfB and gtfC in the Combination Streptococcus mutans ATCC 25175 and Veillonella parvula ATCC 10790T

Setiawan AS, Subarnas A, Djais AA, Milanda T, Ichwan SJA

Journal of Experimental Pharmacology 2025, 17:639-650

Published Date: 8 September 2025

Original Research

Hypoglycemic and Hypolipidemic Effects of Leonotis mollisima Aqueous Leaf Extract in Type 2 Diabetic Rats

Stephen N, Odoma S, Salihu TS, Joshua AO, Timothy N

Journal of Experimental Pharmacology 2025, 17:625-637

Published Date: 6 September 2025

Original Research

Targeting Intestinal Permeability for Graft-versus-Host Disease Treatment: A Therapeutic Perspective with Defibrotide

Rimondi E, Melloni E, Secchiero P, Braidotti S, Maximova N, Marcuzzi A

Journal of Experimental Pharmacology 2025, 17:613-623

Published Date: 4 September 2025

Review

Exploring the Neuroprotective Potentials of Flavonoid Metabolites in Syzygium aromaticum: A Review with in-silico Insight to Therapeutic Potential

Etukudo EM, Usman IM, Oviosun A, Ojiakor VO, Makena W, Owembabazi E, Aja PM, Mutume Nzanzu Vivalya B, Archibong VB, Anyanwu E

Journal of Experimental Pharmacology 2025, 17:587-611

Published Date: 29 August 2025

Original Research

An Agonist of Zinc-Sensing G-Protein Coupled Receptor 39 Accelerates Skin Wound Healing and Protects Against UVB-Induced Keratinocyte Damage

Chatkul P, Wongsawat M, Satianrapapong W, Arinno A, Lamlertthon P, Wachapatthana U, Sucharitakul T, Wachiradejkul W, Sakulpanich D, Petcharat B, Chancharoen W, Liamsuwan T, Pongkorpsakol P

Journal of Experimental Pharmacology 2025, 17:571-585

Published Date: 13 August 2025

Original Research

Effect of 8-Methyl Nonanoic Acid, a Degradation By-Product of Dihydrocapsaicin, on Energy and Glucose Homeostasis in Diet-Induced Obese Mice

Keawsomnuk P, Den-Udom T, Thongin S, Wiriyakulsit N, Mukthung C, Boonthip C, Pittayakhajonwut P, Ketsawatsomkron P, Wichai U, Muta K

Journal of Experimental Pharmacology 2025, 17:555-570

Published Date: 13 August 2025

Original Research

Toxicities Associated with Systemic Administration of Interleukin-6 in Wistar Albino Rats

Nabisubi P, Mugasa CM, Matovu E, Ssekatawa K, Uwituze V, Ssentamu G, Namayanja M, Kato CD

Journal of Experimental Pharmacology 2025, 17:545-554

Published Date: 8 August 2025

Original Research

Hepatoprotective Effects of Gac (Momordica cochinchinensis) Aril Extract in Acetaminophen-Induced Liver Injury: Modulation of Oxidative Stress, Inflammation, and Glucose Metabolism

Lonan P, Ariyabukalakorn V, Yoysungnoen B, Singsai K, Praphasawat R, Sangkham S, Jantarach N, Riyamongkhol P, Somparn N, Munkong N

Journal of Experimental Pharmacology 2025, 17:527-543

Published Date: 5 August 2025

Original Research

Evaluation of Antibacterial Activity of Combined Ethanolic Extracts from Callistemon citrinus Leaves and Mangifera indica Bark Against Streptococcus pneumoniae

Rubayiza P, Mukisa R

Journal of Experimental Pharmacology 2025, 17:519-526

Published Date: 4 August 2025

Original Research

Exploring the Potential of HIV Integrase Inhibitors as Therapeutic Agents Against HSV and HCMV: A Molecular Docking Study

Rao AM, SM F, Somashekara D, Gayam PKR, Rahangdale RR, Patil SS, Hariharapura RC

Journal of Experimental Pharmacology 2025, 17:507-518

Published Date: 23 July 2025

Original Research

Synthesis and Biological Evaluation of Acridone Derivatives for Antimicrobial and Antifungal Applications

Al-Shami AS, Alkadsi J

Journal of Experimental Pharmacology 2025, 17:497-506

Published Date: 22 July 2025

Original Research

Protective Effects of Tamarillo (Solanum betaceum) Extract Against Apoptosis in Lead Acetate-Induced Mice Testicular Damage

I’tishom R, Agustinus A, Khaerunnisa S, Abutari CA, Undaryati YM, Rezano A, Margiana R, Putra WMI

Journal of Experimental Pharmacology 2025, 17:485-496

Published Date: 22 July 2025

Original Research

The Potential Effect of Dapagliflozin and Liraglutide in Attenuating Cardio-Renal Injuries in Diabetic Rats

Albanna AA, Ibrahim DA, Shamsher AM, Al-Shawia MA, Halboup A

Journal of Experimental Pharmacology 2025, 17:467-484

Published Date: 7 July 2025

Original Research

Comparison of Essential Oil Extraction Techniques and Their Therapeutic Applications in Dentistry: Focus on Candida albicans Inhibition

Cuenca-León K, Sarmiento-Ordóñez JM, Pacheco-Quito EM, Benavides-Túlcan SM, Castro NA, Zarzuelo-Castañeda A

Journal of Experimental Pharmacology 2025, 17:455-466

Published Date: 3 July 2025

Review

Peperomia Pellucida (L.) Kunth: A Decade of Ethnopharmacological, Phytochemical, and Pharmacological Insights (2014–2025)

Teodhora, Hendriani R, Sumiwi SA, Levita J

Journal of Experimental Pharmacology 2025, 17:417-454

Published Date: 3 July 2025

Original Research

Assessment of the Impact of Bidens pilosa on Behavioral, Oxidative Stress and Cerebellar Cortical Histoarchitectural Alterations During Bisphenol A Exposure in Mice

Jama IA, Usman IM, Oviosun A, Eze ED, Adeniyi IA, Etukudo EM, Kwizera E, Owembabazi E, Anyanwu E

Journal of Experimental Pharmacology 2025, 17:403-416

Published Date: 27 June 2025

Review

Targeting Molecular Pathways in Breast Cancer Using Plant-Derived Bioactive Compounds: A Comprehensive Review

Al Khalily IA, Megantara S, Aulifa DL

Journal of Experimental Pharmacology 2025, 17:375-401

Published Date: 22 June 2025

Original Research

Gingerols and Shogaols of Zingiber officinale var. sunti Valeton as Potential Allosteric Agonists of Human GABAA Receptor by in silico Pharmacology Approach

Kuswandani F, Wilar G, Wahyuni IS, Megantara S, Pitaloka DAE, Levita J, Jiranusornkul S

Journal of Experimental Pharmacology 2025, 17:359-374

Published Date: 17 June 2025

Original Research

Etlingera Elatior Inflorescence Extract Mitigates Acute Gastric Ulcers by Suppressing the Expression of Inducible Nitric Oxide Synthase in Ethanol-Induced Wistar Rats

Prayoga DK, Aulifa DL, Budiman A, Levita J, Jiranusornkul S

Journal of Experimental Pharmacology 2025, 17:343-357

Published Date: 17 June 2025

Original Research

Zingerone Attenuates Cadmium-Induced Neuroinflammation, Oxidative Stress and Cognitive Deficit on the Prefrontal Cortex of Adult Wistar Rats

Oviosun A, Oviosun EC, Nto NJ, Memudu AE, Anyanwu EG

Journal of Experimental Pharmacology 2025, 17:323-341

Published Date: 13 June 2025

Original Research

Morin Mitigates Methamphetamine-Induced Neurotoxicity: Effects on Motor and Cognitive Function

Anyanwu GE, Umeano AV, Ojiakor VO, Katchy AU, Anyanwu CN, Fakorede S

Journal of Experimental Pharmacology 2025, 17:307-321

Published Date: 11 June 2025

Original Research

Anti-Tyrosinase and Radical Scavenging Activities of Selected Cassipourea Plants and Isolated 7-Methoxygeranin A: Traditional Use as Skin Lighteners

Mpofana N, Paulse M, Yalo M, Dlova NC, Hussein A, Lanrewaju AA, Lukman HY, Aribisala JO, Rautenbach F, Marnewick JL, Sabiu S

Journal of Experimental Pharmacology 2025, 17:287-306

Published Date: 31 May 2025

Original Research

Biocompatibility and Effectiveness of Amphotericin B-Loaded Metal-Organic Structures (AmB-ZIF-8) as Dermal Drug Transporters in Experimental Cutaneous Leishmaniasis

Carreño H, Osorio J, Mejía-Ospino E, Escobar P

Journal of Experimental Pharmacology 2025, 17:269-286

Published Date: 30 May 2025

Review

Small Interfering RNA (siRNA) in Dyslipidemia: A Systematic Review on Safety and Efficacy of siRNA

Alla SSM, Shah DJ, Meyur S, Agarwal P, Alla D, Moraboina SL, Ghadvaje GV, Bayeh RG, Malireddi A, Shajan T, Vineetha B, Sai Prudhvi T, Biziyaremye P

Journal of Experimental Pharmacology 2025, 17:249-267

Published Date: 28 May 2025

Original Research

Aaptamine Alters Vimentin Expression and Migration Capability of Triple-Negative Breast Cancer Cells

Khairani AF, Shalannandia WA, Bashari MH, Atik N

Journal of Experimental Pharmacology 2025, 17:239-247

Published Date: 22 May 2025

Original Research

Antidiabetic Effect of Hydro-Ethanolic Leaf Extract of Sclerocarya Birrea (A. Rich.) Hochst in Wistar Rats

Coulidiaty AGV, Youl ENH, Yaméogo TM, Oladoja FA, Odejobi TA, Ouedraogo R, Awodele O

Journal of Experimental Pharmacology 2025, 17:223-237

Published Date: 17 May 2025

Original Research

The Effects of the Ethanol Extract of Allium Ascalonicum L. in High-Fat-High-Fructose-Induced Insulin Resistance Swiss-Webster Male Mice

Elkanawati RY, Sumiwi SA, Levita J

Journal of Experimental Pharmacology 2025, 17:207-221

Published Date: 16 May 2025

Original Research

Prevention of Hepatalin-Dependent Insulin Resistance Induced by a High Sucrose Diet Using a Synergistic Combination of S-Adenosyl Methionine, Vitamin E and Vitamin C (SAMEC) in Virgin and Pregnant Sprague Dawley Rats

Lovat NEJ, Chowdhury K, Legare DJ, Lautt WW

Journal of Experimental Pharmacology 2025, 17:193-205

Published Date: 15 May 2025

Original Research

Influence of the Solvent and the Harvesting Site on the Content of Phenolic Compounds and the in Vitro Antidiabetic Potential of Leafy Stems and Roots of Phyllanthus amarus Schum. and Thonn.

Zanté AA, Zoungo D, Sanou Y, Kabré P, Ouédraogo RJ, Belemnaba L, Ouattara L, Ouoba P, Ouédraogo GA

Journal of Experimental Pharmacology 2025, 17:181-192

Published Date: 5 May 2025

Original Research

Andrographolide Reduces Cytokine Release and Cyclooxygenase-2 Expression by Inhibiting the JNK and NF-κB Pathways in Glioblastoma Cells Exposed to Cadmium

Kasemsuk T, Vivithanaporn P, Woonfak P, Khemawoot P

Journal of Experimental Pharmacology 2025, 17:169-179

Published Date: 31 March 2025

Original Research

Aaptamine Inhibits Lipid Accumulation and Pparg and Slc2a4 Expression While Maintaining the Methylation of the Pparg Promoter During 3T3-L1 Adipocyte Differentiation

Ariyanto EF, Wijaya I, Pradian ZA, Bhaskara APM, Lastialno MP, Rahman PHA, Bashari MH, Oktavia N, Putra MIP, Pratiwi YS, Heryaman H, Dhianawaty D

Journal of Experimental Pharmacology 2025, 17:159-168

Published Date: 20 March 2025

Original Research

Inhibition of Mitochondrial Dynamics by Mitochondrial Division Inhibitor-1 Suppresses Cell Migration and Metastatic Markers in Colorectal Cancer HCT116 Cells

Mehmood T, Nasir Q, Younis I, Muanprasat C

Journal of Experimental Pharmacology 2025, 17:143-157

Published Date: 18 March 2025

Original Research

Phytochemical Analysis, Computational Study, and in vitro Assay of Etlingera elatior Inflorescence Extract Towards Inducible Nitric Oxide Synthase

Prayoga DK, Pitaloka DAE, Aulifa DL, Budiman A, Levita J, Jiranusornkul S, Nguyen BP

Journal of Experimental Pharmacology 2025, 17:123-141

Published Date: 8 March 2025

Original Research

Antiproliferative Activity and Apoptotic Mechanisms of β-Sitosterol and Its Derivatives as Anti-Breast Cancer Agents: In Silico and In Vitro

Mutakin M, Pangestu L, Hidayat NN, Abdullah FF, Hadisaputri YE

Journal of Experimental Pharmacology 2025, 17:107-121

Published Date: 17 February 2025

Original Research

Hepatoprotective Effects of Cilnidipine in Cholestatic Liver Disease: Role of FXR and NRF2 Signalling

Mohammed TA, Zalzala MH

Journal of Experimental Pharmacology 2025, 17:93-105

Published Date: 17 February 2025

Review

Anti-Inflammatory Activities of Some Plants of Genus Alpinia: Insights from In Vitro, In Vivo, and Human Studies

Yuliawati KM, Febriyanti RM, Sumiwi SA, Levita J

Journal of Experimental Pharmacology 2025, 17:51-91

Published Date: 24 January 2025

Original Research

Two Novel Compounds Isolated from the Marine Fungal Symbiont of Aspergillus unguis Induce Apoptosis and Cell Cycle Arrest in Breast Cancer Cells: In vitro Study

Bashari MH, Agung MUK, Ariyanto EF, Al Muqarrabun LMR, Salsabila S, Chahyadi A, Rosandy AR, Afifah E, Afni M, Atmaja HE, Putri T, Utami F, Subhan B, Syafrizayanti, Andriani Y, Elfahmi

Journal of Experimental Pharmacology 2025, 17:37-50

Published Date: 22 January 2025

Original Research

Oyster Mushroom (Pleurotus ostreatus) Ethanolic Extract Inhibits Pparg Expression While Maintaining the Methylation of the Pparg Promoter During 3T3-L1 Adipocyte Differentiation

Ariyanto EF, Farahana AK, Sudirman GSJ, Widiarsih E, Qomarilla N, Rahayu NS, Wikayani TP, Heryaman H, Wira DW, Triatin RD, Bashari MH, Pamela Y, Pratiwi YS, Ghozali M

Journal of Experimental Pharmacology 2025, 17:27-36

Published Date: 16 January 2025

Original Research

The Suppression of Signal Transducer and Activator of Transcription-3 in A549 human Lung Carcinoma Cells Induced by Marine Sponge Callyspongia aerizusa

Hadisaputri YE, Nurhaniefah AA, Mutakin M, Hendriani R, Rezano A, Sopyan I, Yusnaini Y, Asikin Y, Abdulah R

Journal of Experimental Pharmacology 2025, 17:15-25

Published Date: 11 January 2025

Review

Efficacy of Probiotic Supplements and Topical Applications in the Treatment of Acne: A Scoping Review of Current Results

Sutema IAMP, Latarissa IR, Widowati IGAR, Sartika CR, Ciptasari NWE, Lestari K

Journal of Experimental Pharmacology 2025, 17:1-14

Published Date: 9 January 2025