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Journal of Inflammation Research

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ISSN: 1178-7031

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Bone-Immune System Crosstalk in Musculoskeletal Health and Disease

Acute inflammation is a fundamental reparative response to injury in musculoskeletal tissues, orchestrating the recruitment of immune cells and the coordinated activity of osteoblasts, osteoclasts, and chondrocytes to remodel and restore damaged bone and cartilage. This intricate process is governed by a sophisticated network of immune signaling pathways and immunometabolic cues, maintaining a delicate homeostatic balance. The emerging field of osteoimmunology is dedicated to deciphering this critical crosstalk. The goal of this Article Collection is to bring to light the pivotal role that bones and the musculoskeletal system play in health and disease.