Journal of Inflammation Research

Lysophosphatidylcholine as a Novel Diagnostic Biomarker in Kawasaki Disease: Based on Immunometabolism-Related Signature

Ma X, Zheng Y, Feng C, Zhang M, Wang H, Li X

Journal of Inflammation Research 2025, 18:18343-18355

Published Date: 31 December 2025

Endoscopic Retroperitoneal Debridement Combined with Posterior Percutaneous Pedicle Screw Fixation for Lumbar Infectious Spondylodiscitis: A Retrospective Study and Preliminary Results

Yang Y, Ruan W, Li J, Dang R, An H, Zhao W, Xu L, Tan H

Journal of Inflammation Research 2025, 18:18331-18342

Published Date: 31 December 2025

Case report

Dermatological Inflammation

Dupilumab-Induced Systemic Hypoperfusion in an Elderly Patient: A Case Report

Feng H, Liu Y, Dong X, Zhou L

Journal of Inflammation Research 2025, 18:18323-18329

Published Date: 31 December 2025

The eNAMPT-Integrin α5β1 Axis Mediates Neutrophil-Endothelial Cell Interactions Driving Inflammation in Ulcerative Colitis

Di Y, Ji W, Xiong W, Song W, Chen G, Li D, Qi F

Journal of Inflammation Research 2025, 18:18307-18321

Published Date: 30 December 2025

LncRNA PCED1B-AS1 Inhibits Sepsis-Induced Acute Kidney Injury by Promoting Transformation of Macrophages from M1 to M2 Type via Regulating the miR-361-3p/SOCS1 Axis

Huang P, Li Y, Wang S, Wu Y, Zhang S

Journal of Inflammation Research 2025, 18:18291-18306

Published Date: 30 December 2025

Siji Kangbingdu Mixture Ameliorates LPS-Induced Acute Lung Injury by Downregulating the TNF/IL-17 Signaling Pathways: A Comprehensive Study Using Transcriptomics, Network Pharmacology and Experimental Verification

Wang Y, Zhou H, Wang B, Liu Y, Long K, Zhang H

Journal of Inflammation Research 2025, 18:18267-18290

Published Date: 30 December 2025

Integrative Machine Learning Analysis of Programmed Cell Death Pathways Identifies Novel Diagnostic Biomarkers for Atrial Fibrillation

Peng H, Xia Z, Zhao Y, Xie D

Journal of Inflammation Research 2025, 18:18247-18266

Published Date: 30 December 2025

Multi-Target Therapeutic Effects of YuPingTongQiao (YPTQ) in Allergic Rhinitis: A Traditional Chinese Medicine Restoring Dysregulated TFR Cells and Reinforcing Epithelial Barrier Integrity

Jiang Y, Chen H, Guo Y, Yao Z, Shi J, Shen S, Lai C, Dai L, Cao W, Li J

Journal of Inflammation Research 2025, 18:18229-18245

Published Date: 30 December 2025

Exploring the Potential Value of Lactylation and Macrophage Polarization-Related Genes as Biomarkers for TNF-α Inhibitor Response in Inflammatory Bowel Disease

Han L, Lin G, Lv X, Li S, Huang Z, Li Y, Chen D, Chen X, Lin J, Chen L, Lv X

Journal of Inflammation Research 2025, 18:18205-18228

Published Date: 30 December 2025

Eosinophilic Granulomatosis with Polyangiitis Presenting as Acute Abdomen: A Rare Case Report

Liao Y, Xiong J, Huang W

Journal of Inflammation Research 2025, 18:18193-18204

Published Date: 28 December 2025

Tellimagrandin II Stimulates Inflammasomes by Causing an Accumulation of 3-Aminopropanal, Which Promotes Apoptosis of Endometriotic Cells While Inhibiting Invasion

Fan W, Zhang Y, Zhao R

Journal of Inflammation Research 2025, 18:18181-18192

Published Date: 29 December 2025

Neutrophils Extracellular Traps Impair Lung Endothelial Proliferation in Sepsis via PLK1 Inhibition and Cell Cycle Arrest

Zhu C, Qu M, Wu D, Shi Y, Zeng F, Miao C, Zhou D

Journal of Inflammation Research 2025, 18:18165-18180

Published Date: 27 December 2025

Plasma Bile Acid Profiling Reveals Novel Early Diagnostic Biomarkers for Pediatric Sepsis

Zhang L, Liu J, Chen Y, Lu X, Li K, Li W, Li N, Li F, Wang Y, He D, Sun Z, Guo L, Zhang Q

Journal of Inflammation Research 2025, 18:18151-18163

Published Date: 26 December 2025

Original Research

Gastrointestinal Inflammation

The Potential of High-Density Lipoprotein as a Predictive Biomarker for Infliximab Efficacy in Crohn’s Disease

Tang K, Peng Z, Xu D, Li Y, Liu X, Lian G, Peng Y

Journal of Inflammation Research 2025, 18:18137-18149

Published Date: 26 December 2025

Ferroptosis in Hypertriglyceridemic Acute Pancreatitis: Mechanisms and Therapeutic Implications

Zou K, Liu W, Xia W, Zhao Y

Journal of Inflammation Research 2025, 18:18115-18135

Published Date: 24 December 2025

The Neuroimmune Axis in Atopic Dermatitis: From Pathogenic Mechanisms to Targeted Neuroimmunotherapy

Zhang Z, Chang C, Xiao L, Su H, Lyu Y, Zhao J, Chen J, Gou K, Zhou J, Wang C, Zhu X, Fu S, Lu M, Shi L

Journal of Inflammation Research 2025, 18:18079-18113

Published Date: 25 December 2025

Effects of Hypoglycemic Agents on Pulmonary Diseases: A Comprehensive Narrative Review

Yang Y, Wang K, Chen S

Journal of Inflammation Research 2025, 18:18053-18078

Published Date: 24 December 2025

Combined Pan-Immune-Inflammation Value and Prognostic Nutritional Index as a Prognostic Biomarker for Colorectal Cancer Undergoing Enterectomy

Chen Z, Liang L, Pan C, Ju H, Li J, Yang M, Yang J, Zhao T

Journal of Inflammation Research 2025, 18:18039-18052

Published Date: 24 December 2025

Development of a Nomogram for Predicting Multiple Organ Dysfunction in Acute Pancreatitis

Che Z, Zhao X, Xue W, Wang Z, Hu C, Feng Y, Ru R, Tian Y, Mo S

Journal of Inflammation Research 2025, 18:18025-18037

Published Date: 24 December 2025

The Effects of Da-Chai-Hu Decoction Alleviating Pancreatic Exocrine Dysfunction by Inhibiting Endoplasmic Reticulum Stress of Acinar Cell in Mice with Chronic Pancreatitis

Yan Z, Chen X, Cao X, Fan J, Duan L, Wu N, Xin J, Li X, Xu X, Zhang H

Journal of Inflammation Research 2025, 18:18009-18024

Published Date: 22 December 2025

Immune Response to TB Antigen Stimulation in Type 2 Diabetes Mellitus: Insights from a Cross-Sectional Cytokine Profile Analysis

Soetedjo NNM, Koesoemadinata RC, Rahmadika N, Indrati AR, Mudjanarko SW, Permana H, Alisjahbana B, Parwati I

Journal of Inflammation Research 2025, 18:17997-18008

Published Date: 22 December 2025

Original Research

Gastrointestinal Inflammation

Development of Predictive Models for Long-Term Endoscopic Response to Ustekinumab in Crohn’s Disease Based on Plasma Proteomics

Wu C, Zheng J, Qian X, Peng C, Zhou F, Wang L

Journal of Inflammation Research 2025, 18:17983-17996

Published Date: 22 December 2025

Mechanistic Insights into the Therapeutic Potential of Phytochemicals Against Stress-Induced Gastric Ulcer

Paulraj RS, Sathiyaseelan A, Perumal P, Ramachandran A

Journal of Inflammation Research 2025, 18:17961-17981

Published Date: 22 December 2025

Integrating Extracellular Vesicles Proteomics and Clinical Parameters to Develop a High-Precision Predictive Model for Severe Asthma

Qian Y, Wang F, Gao J, Jiang Z, Gao X, Chen Z

Journal of Inflammation Research 2025, 18:17945-17960

Published Date: 23 December 2025

Review

Dermatological Inflammation

Inflammatory Skin Disease in Latin America: Treatment Challenges and Opportunities

Mazzuoccolo LD, Angles MV, Cappetta ME, Soriano ER

Journal of Inflammation Research 2025, 18:17927-17944

Published Date: 22 December 2025

A Prognostic Nomogram Combining Postoperative SII and PIV Improves Long-Term Survival Prediction in NSCLC

Yu Q, Zheng L, Iqbal M, Xiang J, Tang J

Journal of Inflammation Research 2025, 18:17911-17926

Published Date: 22 December 2025

Topological Radiomics in Predicting Mucosal Healing and Activity Score of Crohn’s Disease Using Multi-Task Deep Learning

Tang K, Wu X, Li J, Yu L, Yang L, Zhang Y, Zhang L, Wang Y, Li K

Journal of Inflammation Research 2025, 18:17895-17910

Published Date: 23 December 2025

Comprehensive Review of Sepsis-Related Skeletal Muscle Atrophy: Mechanisms, Diagnosis and Therapeutic Strategies

Wu Q, Huang Q, Xu Z, Hou C, Wang C

Journal of Inflammation Research 2025, 18:17879-17894

Published Date: 21 December 2025

Review

Neuroinflammation

Targeting the IL-4/IL-4R Axis in Th2 Inflammatory Diseases: A Review of Clinical Efficacy and Safety

Li W

Journal of Inflammation Research 2025, 18:17857-17877

Published Date: 21 December 2025

Comment on the Review: Clarifying Steroid-Associated Glaucoma—from Association to an Actionable Closed-Loop [Response to Letter]

Izquierdo-Escamez R, Belletti M, Tornero C, Olivas-Vergara OM, Peiteado D, Carreño E

Journal of Inflammation Research 2025, 18:17853-17855

Published Date: 21 December 2025

The Efficacy of Combined Lamotrigine and Levetiracetam Therapy in Epileptic Patients and Its Effects on Hippocampal Volume and Neuroinflammatory Response

Li P, Qi A, Ma J, Li A, Sun Z

Journal of Inflammation Research 2025, 18:17843-17851

Published Date: 20 December 2025

Serum Pyroptosis-Related Cytokines as Biomarkers for Diagnostic Assessment and Risk Stratification of Ocular Graft-versus-Host Disease: A Case-Control Study

Lou J, Xu Y, Zhuang X, Zhao Y, Pan H, Chen Y, Zhang X, Lu P

Journal of Inflammation Research 2025, 18:17825-17841

Published Date: 19 December 2025

Multi-Omics Integration Identifies FGF1 as a Diagnostic Biomarker and RAS-MAPK-Driven Pathogenic Factor in Osteoarthritis

Yan Y, Wang C, Zhang M, Jiang X, Cheng W

Journal of Inflammation Research 2025, 18:17803-17824

Published Date: 20 December 2025

Original Research

STK11 Alleviates Pulmonary Inflammation During Acute Lung Injury by Phosphorylating AMPK to Activate Autophagy in A549 Cell Model

Xiao R, Qi Z, Chen T, Wei F

Journal of Inflammation Research 2025, 18:17789-17802

Published Date: 19 December 2025

Original Research

Anti-Inflammatory Combinations Targeting Oncostatin M Gene to Remodel Intestinal Flora and Alleviate Inflammation of Perianal Ulcer in Rats

Wu Y, Ge H, Zhao H, Zou K, Wang P, Wang Y, Zhang Y

Journal of Inflammation Research 2025, 18:17769-17788

Published Date: 17 December 2025

Case Series

Severe Dry Cough Followed by Eosinophilia Without Pulmonary Infiltrates After Dupilumab Treatment in Patients with Severe Asthma: A Series of Five Cases

Chen Y, Xie J

Journal of Inflammation Research 2025, 18:17759-17768

Published Date: 17 December 2025

Development and Validation of an Explainable Machine Learning Model for Gangrenous Cholecystitis Prediction: A Multicenter Retrospective Study

Hu Y, Chen Y, Zhao H

Journal of Inflammation Research 2025, 18:17747-17758

Published Date: 17 December 2025

Age-Specific Cytokine Profiling in Children with Mycoplasma Pneumoniae Infections in Post-COVID-19 Era: A Retrospective Study

Sun Y, Tong L, Lin M, Huang Z, He J, Su L, Ying S, Chen Z

Journal of Inflammation Research 2025, 18:17731-17746

Published Date: 17 December 2025

Original Research

Neuroinflammation

Wnt3a Inhibits Inflammatory Responses and Improves Survival in Immortalised Schwann Cells

Zheng J, Zhang Y, Nan G

Journal of Inflammation Research 2025, 18:17715-17730

Published Date: 18 December 2025

Original Research

Musculoskeletal Inflammation

Downregulated MYL1 Emerges as a Promising Diagnostic Biomarker for Rheumatoid Arthritis

Yang C, Huang Z, Zheng X, Tang H, Qin W, Liang Y, Chen H, Hao W, Yi D, Lu WW, Chen Y

Journal of Inflammation Research 2025, 18:17693-17714

Published Date: 18 December 2025

SULF1’s Role in Endothelial Senescence and Atherosclerosis: Insights from Single-Cell and Bulk Transcriptomics

Jiang MT, Wan SL, Shen XY, Zhang ZB, He ZQ, Hu YX, Liang C

Journal of Inflammation Research 2025, 18:17677-17692

Published Date: 16 December 2025

Therapeutic Effect of Brain Awakening and Mind Opening Acupuncture Combined with Simiao Pill on Mice with Benign Prostatic Hyperplasia

Luo Z, Yang X, Zhang J, Zhang B, Zhao Q, Cui L, Bo H

Journal of Inflammation Research 2025, 18:17663-17675

Published Date: 15 December 2025

Uncovering Circular RNA Signatures in Rheumatoid Arthritis: Novel Biomarkers and Clinical Implications

Yang X, Yang Z, Zhang M, Xu S, Shuai Z

Journal of Inflammation Research 2025, 18:17651-17662

Published Date: 16 December 2025

ITGB7 Remodels Inflammation and Immune Microenvironment and Enhances Checkpoint Inhibitor-Based Immunotherapy in Pancreatic Cancer

Zhu Y, Lei Y, Luo A, Zhang Q, Cai L, Zhang Y, Li X, Wang B, Sun D, Li Y, Sun P, Gong S, Cheng Y

Journal of Inflammation Research 2025, 18:17633-17649

Published Date: 16 December 2025

Mechanisms of Viral Oncogenesis: DNA and RNA Viruses in Human Cancer

Yao N, Huang B

Journal of Inflammation Research 2025, 18:17611-17631

Published Date: 15 December 2025

Identifying Genetic Factors Influencing the Development of Anti-Drug Antibodies in Inflammatory Bowel Disease: A Scoping Review

Culmsee-Holm FB, Buhl E, Kraaer MT, Steenholdt C, Ainsworth MA

Journal of Inflammation Research 2025, 18:17589-17610

Published Date: 17 December 2025

Identification of Novel Biomarkers and Potential Therapeutic Targets for Systemic Sclerosis: An Integrated Analysis of Plasma Proteome-Wide Mendelian Randomization and Transcriptome

Li H, Li Q, Chen X, Mo L, Wang Y, Liu X, Wang X, Qu Z, Wang J, Li Y

Journal of Inflammation Research 2025, 18:17561-17588

Published Date: 17 December 2025

Deciphering the Therapeutic Mechanisms of Banxia Xiexin Decoction Against Ulcerative Colitis: Targeting Pyroptosis and Necroptosis

Lu J, Liang K, Zhang L, Cui B, You L, An R, Hu C, Wang X

Journal of Inflammation Research 2025, 18:17537-17560

Published Date: 16 December 2025

Synthetic 1,3,6-Tri-O-Galloyl-α-D-Glucose Mimics the Hippo Pathway Inhibitor VT107 in Suppressing Concanavalin A-Induced Inflammation in Human Glioblastoma Cells

Konan AS, Zilinski R, Tadrous M, Zgheib A, Gaudreault R, Annabi B

Journal of Inflammation Research 2025, 18:17523-17535

Published Date: 19 December 2025

Serum Levels of TNFAIP3 and NLRP3 as Novel Biomarkers for Major Adverse Cardiovascular Events in Patients with Chronic Heart Failure: A Cohort Study

Mo D, Yang L, Zhang P, Zhang M, Guan J, Wang G, Dai H

Journal of Inflammation Research 2025, 18:17509-17521

Published Date: 16 December 2025

Original Research

Cardiovascular Inflammation

Hematological Inflammatory Gradient Score (HIGS): A Novel Predictor of Early Mortality After Coronary Artery Bypass Grafting

Söylemez N, Karaca Ö, Toprak B, Bora R, Bilgiç A, Yılmaz S

Journal of Inflammation Research 2025, 18:17495-17508

Published Date: 16 December 2025

Time-Weighted Cumulative High-Sensitivity C-Reactive Protein and Risk of Cardiac Conduction Block: Findings from a Prospective Cohort

Zhang M, Shi D, Chen Y, Liao Y, Liu Z, Fu R, Bian Y, Chen S, Zhao H, He H, Zu C, Liu C, Huo H, Wu S, Wu Y

Journal of Inflammation Research 2025, 18:17477-17493

Published Date: 14 December 2025

Mechanism of Chronic Atrophic Gastritis: A 20-Year Bibliometric Analyses

Dai YK, Li DY, Cong LL, Liao Y, Wang XC, Fan JW, Chen WJ, Fan CH, Ma T, Wu YJ

Journal of Inflammation Research 2025, 18:17457-17475

Published Date: 14 December 2025

To Explore the Mechanism of Cuproptosis in Psoriasis Based on Bioinformatics and in vivo Experiments

Ma Y, Sun Y, Yao J, Zhang J, Wang H, Yang S

Journal of Inflammation Research 2025, 18:17433-17456

Published Date: 13 December 2025

Variations in Platelet Count Associated with the Occurrence of Infected Pancreatic Necrosis, Surgical Intervention, and Mortality in Acute Pancreatitis: A Retrospective Cohort Study

Sun W, Zhao B, Wang Z, Mao E, Li Y, Che Z

Journal of Inflammation Research 2025, 18:17421-17432

Published Date: 13 December 2025

Dihydromyricetin Improves Ulcerative Colitis by Suppressing NLRP3 Inflammasome Activation Caused by Dysbiosis of Gut Microbiota

Chen J, Ding S, Yang H, Dai Y, Zhang Z, Zhu T, Cao L, Hu B, Liu H

Journal of Inflammation Research 2025, 18:17401-17420

Published Date: 13 December 2025

Gut Microbiota Characteristics in Acute Pancreatitis Patients and Their Association with SIRS and Organ Failure: An Experimental Study

Wang Q, Zhang K, Ding Z, Si G, Shen F, Yu S

Journal of Inflammation Research 2025, 18:17387-17399

Published Date: 13 December 2025

Review

Dynamic Regulation of Macrophage Polarization in Acute Myocardial Infarction and Its Therapeutic Potential

Xu A, Xu S, Tan X, Sun Q, Song Y, Nong Y, Wang X, Zeng Y, Fan H, Zhou Y

Journal of Inflammation Research 2025, 18:17363-17385

Published Date: 13 December 2025

Original Research

Chinese Medicine Formula HJ11 Alleviates Atherosclerosis by Inactivating the TLR4/MyD88/IκB-α Pathway and Modulating the Heart-Gut Axis Response

Zhang F, Lu F, Shi M, Xu W, Li Z, Cui Y, Zou J, Hu J

Journal of Inflammation Research 2025, 18:17343-17362

Published Date: 11 December 2025

Review

Respiratory Inflammation

Established and Emerging Biological Therapies for the Treatment of Comorbid Asthma and Chronic Obstructive Pulmonary Disease

Cazzola M, Matera MG, Hanania NA, Rogliani P

Journal of Inflammation Research 2025, 18:17319-17341

Published Date: 11 December 2025

Corynebacterium Striatum Infective Endocarditis: A Systematic Review

Hong M, Xiang W, Kong L, Wang X, Fu L, Chen L, Liu F

Journal of Inflammation Research 2025, 18:17309-17318

Published Date: 11 December 2025

Pharmacological Mechanisms of CheReCunJin Formula in Ameliorating Sjögren’s Syndrome: Suppression of IL-17 Signal-Mediated Inflammatory Cascade

Gan Y, Du L, Sun Y, Li F, Chen H, Yan S, Xiao X, Li S, Wu B

Journal of Inflammation Research 2025, 18:17289-17308

Published Date: 10 December 2025

Exploring the Mechanism of CaoHuangGuiXiang Formula in Ameliorating Systemic Candida albicans Infection: A Study Integrating Network Pharmacology and Animal Experiments

Yue H, Liu S, Bai Y, Zhu W, Tian J, Xu X, Liu Q

Journal of Inflammation Research 2025, 18:17271-17287

Published Date: 9 December 2025

Interleukin-27 and Interleukin-2 Cooperatively Regulate CD4⁺ T Cell Subsets and Immune Imbalance in Coronary Artery Disease

Cai Y, Tang H, Tang W, Tang W, Xu W, Wang Y, Ding Y, Yu J, Pan C, Li Z, Peng Y, Zhu R, Yu K, Zeng Q, Zhong Y

Journal of Inflammation Research 2025, 18:17253-17269

Published Date: 10 December 2025

LncRNA NONHSAT248596.1 Promotes Osteoarthritis via miR-146a-5p/CXCR4 Axis by Inducing Chondrocyte Apoptosis and Extracellular Matrix Degradation

Yang X, Yang G, Yang T, Song E, Xiang Y, Shi Z, Yu Y, Wang G, Li Y

Journal of Inflammation Research 2025, 18:17235-17252

Published Date: 10 December 2025

Anti-Inflammatory and Anticancer Potential of Solanum tuberosum L. Bioactive with Proposed Mechanisms in Oral Squamous Cell Carcinoma: A Scoping Review

Andayasari L, Shidiq A, Sufiawati I

Journal of Inflammation Research 2025, 18:17223-17233

Published Date: 10 December 2025

The Predictive Value of NLR, PLR, LMR, NPAR and D-Dimer on the Efficacy and Prognosis of First-Line Immunotherapy for Extensive-Stage Small Cell Lung Cancer

Shen Y, Wang J, Hua Q, Dong M

Journal of Inflammation Research 2025, 18:17211-17222

Published Date: 10 December 2025

The Pathological Link Between Elevated Markers of Inflammation, Endothelial Activation, and Cardiovascular Diseases in People Living with HIV on Combination Antiretroviral Therapy: A Systematic Review

Mokoena H, Hanser S, Mabhida SE, Choshi J, Sekgala MD, Nkambule BB, Mchiza ZJ, Ndwandwe DE, Kengne AP, Dludla PV

Journal of Inflammation Research 2025, 18:17197-17210

Published Date: 10 December 2025

Prognostic Significance of Preoperative Inflammatory and Liver Fibrosis Markers in Hepatocellular Carcinoma

Cheng J, Pan Y, Li X, Lu M, Zhang Y, Wu J, Ye L, Liu X

Journal of Inflammation Research 2025, 18:17185-17196

Published Date: 9 December 2025

The Role of Mitochondrial Regulation in Macrophage Polarization: Implications for the Pathogenesis of Rheumatoid Arthritis

Li P, Wang G, Peng Z, Zhang L, Yang F, Wei Y, Pan M, Zang H, Zhou M

Journal of Inflammation Research 2025, 18:17163-17183

Published Date: 8 December 2025

Catalpol Alleviates HFpEF via Inhibition of the S100A8-RAGE-NOX4 Inflammatory Axis in Murine Hearts

Cao Y, Li S, Zhang Y, He M, Shen Y

Journal of Inflammation Research 2025, 18:17143-17161

Published Date: 8 December 2025

Mechanistic Study of CD90-Positive Synovial Fibroblasts in the Invasion and Recurrence of Pigmented Villonodular Synovitis

Kong L, Chen H, Zhang H, Zhang X, Chen J, Nie Y, Su Z, Lin L

Journal of Inflammation Research 2025, 18:17129-17142

Published Date: 8 December 2025

MCC950 Alleviates Experimental Autoimmune Neuritis by Inhibiting NLRP3 Inflammasome Activity and Down-Regulating Interleukin-23/Interleukin-17 Axis Expression

Li Y, Li X, Gu T, Wang L, Song M, Yang L, Huang Q, Yang J

Journal of Inflammation Research 2025, 18:17113-17127

Published Date: 6 December 2025

Cuproptosis and Immune Microenvironment Interplay in Temporal Lobe Epilepsy: Identification of Key Molecular Signatures and Therapeutic Targets

Li W, Guo Q, Li X, Huang L, Liu H, Liu S

Journal of Inflammation Research 2025, 18:17089-17112

Published Date: 5 December 2025

Serum Cytokines as Predictive Biomarkers for Disease Severity in Pediatric Adenovirus Pneumonia

Xiao J, Liu L, Zhang L, Wu S, Sheng W, Zhao M

Journal of Inflammation Research 2025, 18:17077-17088

Published Date: 5 December 2025

Comment on the Review: Clarifying Steroid-Associated Glaucoma—From Association to an Actionable Closed-Loop [Letter]

Xu L, Chen X, Liu G

Journal of Inflammation Research 2025, 18:17073-17075

Published Date: 5 December 2025

Original Research

Muscarinic Receptor-Mediated Electroacupuncture Modulation of Reactive Enteric Glial Cells Ameliorates Postoperative Ileus

He J, Huang R, Ouyang J, Zhao G, Zhong M

Journal of Inflammation Research 2025, 18:17057-17072

Published Date: 6 December 2025

Association of NLR and Ferritin in Osteoporotic Fractures Among Chinese Older Patients

Jiao HT, Liu ZH, Zhou P, Yuan S, Lu K, Li C

Journal of Inflammation Research 2025, 18:17045-17056

Published Date: 4 December 2025

Huanglian Jiedu Decoction Alleviates Myocardial Ischemia-Reperfusion Injury via AKT-Mediated Regulation of Endoplasmic Reticulum Stress

Gu M, Xu J, Liao Z, Lin J, Li R, Wu W, Qiu Y

Journal of Inflammation Research 2025, 18:17025-17044

Published Date: 3 December 2025

Integrated Multi-Omic Analysis Reveals Causal Relationships and Causal Mechanisms of Peripheral Lymphocyte-Driven Remodeling in the Intrahepatic Immune Microenvironment of Early-Stage MAFLD

Guo S, Li Z, Han Z, Ge Y, Shi H, Zheng Y, Tan W, Xing C, Li Z, Li Y, Song J

Journal of Inflammation Research 2025, 18:17005-17023

Published Date: 3 December 2025

Association Between the Systemic Immune-Inflammation Index and 24-week Outcomes in Patients with HIV-Associated Cryptococcal Meningitis: Secondary Analysis of a Prospective Multicenter Cohort Study

Zhao T, Wang X, Song Y, Harypursat V, Chen Y

Journal of Inflammation Research 2025, 18:16991-17003

Published Date: 3 December 2025

Predictive Value of Traditional and Novel Composite Inflammatory Indicators for Severe and Refractory Mycoplasma pneumoniae Pneumonia in Children

Fan GZ, Zhu YH, Hu LX, Qu ZH, Liu YB

Journal of Inflammation Research 2025, 18:16981-16990

Published Date: 3 December 2025

Platelet Indices and ApoA1 as Predictive Markers in Neoadjuvant Immunochemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma: A Retrospective Study

Zeng T, Liu YC, Wang XH, Yan J, Li SB, Deng D, Xing S

Journal of Inflammation Research 2025, 18:16967-16980

Published Date: 3 December 2025

Elevated Serum HMGB1 Levels and Their Association with Stroke Risk of Paroxysmal Atrial Fibrillation

Gu L, Zhou J, Jin Q, Xu Z, Li W, Cui J, Zhang H

Journal of Inflammation Research 2025, 18:16957-16965

Published Date: 3 December 2025

Original Research

Single-Cell RNA Sequencing Reveals Microglial Heterogeneity and Functional States After Cerebral Ischemia-Reperfusion Injury

Tang Y, Zhang Q, Qu Y, Yi L, Li F, Qu C, Shi S, Pan BF, Wen S, Sun R, Pan Y

Journal of Inflammation Research 2025, 18:16931-16956

Published Date: 3 December 2025

Original Research

Peripheral Levels of Selected Biomarkers in Patients with Post-Sarcoidosis Chronic Fatigue Syndrome

Małujło-Balcerska E, Bączek K, Górski W, Kumor-Kisielewska A, Gwadera Ł, Białas AJ, Piotrowski WJ

Journal of Inflammation Research 2025, 18:16921-16930

Published Date: 2 December 2025

Integration of Delta-Radiomics Features and Inflammatory Biomarkers for Neoadjuvant Chemo-Immunotherapy Efficacy in Locally Advanced Esophageal Squamous Cell Carcinoma

Xu B, Zhu J, Fan T, Lian J, Ma J, Zhou Y, Lu H

Journal of Inflammation Research 2025, 18:16907-16919

Published Date: 3 December 2025

Preliminary Retrospective Analysis of X-Ray, CT, and MRI Imaging Features of Brucellar Spondylodiscitis Diagnosis

Pu Y, Fu XW, Qi M, Wei JL, Shan QL, Gan W, Cun XH, Li X

Journal of Inflammation Research 2025, 18:16891-16905

Published Date: 3 December 2025

NCF2 as a Novel Diagnostic Biomarker in Ulcerative Colitis: Linking Macrophage Infiltration to Immune Dysregulation via Multi-Omics Analysis

Zhang F, Zhu J, Liu H, Ye J, Li Y, Wang B

Journal of Inflammation Research 2025, 18:16871-16890

Published Date: 3 December 2025

Utility of Machine Learning to Characterize Gut Microbiota Dysbiosis and Its Clinical Implications in Inflammatory Bowel Disease

Lee JY, Kim DH, Choi JW, Shong M, Lee CK

Journal of Inflammation Research 2025, 18:16857-16870

Published Date: 2 December 2025

Immune Mechanisms and Pain in Intervertebral Disc Degeneration

Cheng H, Wang L, Huang C, Yang Z, Wu H, Fang Z

Journal of Inflammation Research 2025, 18:16843-16855

Published Date: 1 December 2025

Multi-Omics Association Analysis of Mitochondrial Genes in Hypertrophic Scars: Application of Mendelian Randomization

Gong T, Wu M, Zheng J, Chen Z

Journal of Inflammation Research 2025, 18:16825-16842

Published Date: 2 December 2025

Original Research

Musculoskeletal Inflammation

Identification of Cystatin 3 as a Potential Diagnostic Biomarker for Osteoporosis Using Machine Learning

Liu H, Feng Y, Lin B, Zhang L, Wu B, Wu J

Journal of Inflammation Research 2025, 18:16805-16823

Published Date: 1 December 2025

TLR4 Induces PANoptosis in Annulus Fibrosus Cells by Activating NLRP12 in Intervertebral Disc Degeneration

Zheng F, Cao L, Fu J, Luo M, Yue W, Ma Y, Chen B, Zhai Y, Liu C

Journal of Inflammation Research 2025, 18:16789-16804

Published Date: 1 December 2025

Association of the Cumulative Inflammatory Index and Long-Term Mortality in Stroke-Associated Pneumonia

Gao J, Wen Y, Xie M, Yuan K, Wang H, Sun S, Ma M, Xu G

Journal of Inflammation Research 2025, 18:16777-16787

Published Date: 2 December 2025

Comments on “Temporal Relationship Between Visceral Fat and Inflammation, and Their Joint Effect on Cardiometabolic Diseases: Evidence from the China Health and Retirement Longitudinal Study (CHARLS)” [Response to Letter]

Lin M, Tan X, Chen Y

Journal of Inflammation Research 2025, 18:16773-16776

Published Date: 1 December 2025

Review

Neuroinflammation

The Ketogenic Diet: An Anti-Inflammatory Treatment for Schizophrenia?

Hung AA, Krycer JR, Sarnyai Z, Palmer CM, Navarro S

Journal of Inflammation Research 2025, 18:16761-16771

Published Date: 1 December 2025

Development and Internal Validation of a Nomogram for Predicting Acute Kidney Injury After Cardiac Valve Surgery Using the Serum Uric Acid-to-Albumin Ratio

Zhao X, Wang J, Bai W, Zhang W, Huang C, Qin Z, Wei K, Han M, Yan L, Gu Y, Shao F

Journal of Inflammation Research 2025, 18:16747-16760

Published Date: 28 November 2025

Aging-Associated CD55⁺ Fibroblasts Promote Chronic Inflammation and ECM Dysregulation in Sarcopenia

Xie X, Zhao J, Wu T, Yang Y, Zong Y, Li L, Gao Y, Jiang L, Cao Y, Shen L

Journal of Inflammation Research 2025, 18:16729-16746

Published Date: 28 November 2025

Targeting PANoptosis in Bacterial-Induced Inflammatory Diseases: Mechanisms and Therapeutic Interventions

Wang T, Lu Y, Zhang X, Yu F

Journal of Inflammation Research 2025, 18:16713-16728

Published Date: 27 November 2025

Differential Mediating Roles of Immune-Inflammatory Cells in ≥HSIL Women: A Focus on HPV and CD4/CD8 or NLR

Tong Y, Gao Y, Wu X, Kang Y, Zheng H, Yu R, Zhong H, Mao X

Journal of Inflammation Research 2025, 18:16699-16712

Published Date: 27 November 2025

Multi-Omics Mendelian Randomization Identifies Therapeutic Targets for Sjögren’s Disease with Clinical and Bayesian Validation

He J, Li K, Guo Z, Zhou X, Tang X

Journal of Inflammation Research 2025, 18:16685-16698

Published Date: 27 November 2025

Neutrophil-to-Lymphocyte Ratio as a Prognostic Marker for Hospital-Acquired Infections in Neurosurgical Patients

Jabłońska R, Ślusarz R, Zając M, Królikowska A, Filipska-Blejder K, Sokal P

Journal of Inflammation Research 2025, 18:16667-16684

Published Date: 27 November 2025

Identification of Mitochondrial Unfolded Protein Response-Related Genes and Diagnostic Biomarkers in Atherosclerosis by Integrative Multidimensional Analysis and Experimental Validation

Wu S, Liu Y, Li Y, Lai J, Wan Q, Wu J, Ma Y

Journal of Inflammation Research 2025, 18:16637-16665

Published Date: 27 November 2025

Chronic Exposure to Cigarette Smoke Induces Pyroptosis in Pulmonary Epithelial Cells via EGR1/USP44/TRAF6 Axis in COPD

Cao C, Zhong Z, Wu B, Zou B, Jia H, Xu J, Xiao G, Xia S

Journal of Inflammation Research 2025, 18:16619-16635

Published Date: 27 November 2025

The YTHDC1-m6A-MEG3 Regulatory Axis in Radiation-Induced Liver Injury: Deciphering Early-Stage Epitranscriptomic Alterations and Molecular Dynamics

Guo CY, Du YF, Yan HCHC, Tian FQ, Xu P

Journal of Inflammation Research 2025, 18:16611-16618

Published Date: 27 November 2025

Advancing Gouty Arthritis Research: The Clinical Value of Complete Blood Cell Count Ratios and Immune-Inflammatory Interactions

Gao L, Liu C, Ye G, Gao Y, Wang H

Journal of Inflammation Research 2025, 18:16597-16610

Published Date: 26 November 2025

The Combined Prognostic Value of the Systemic Immune-Inflammation Index and LDL-C in Patients with AMI Undergoing PPCI

Zhang X, Liu A, Li C, Pan Y, Jiao S, Wang Y, Pu H, Liu Y, Zhu H, Pan D

Journal of Inflammation Research 2025, 18:16579-16596

Published Date: 27 November 2025

Maxing Shigan Decoction Alleviates Lung Heat Syndrome by Inhibiting α4β7-Mediated γδT17 Cell Migration Across the Gut-Lung-Nasal Axis

Zhao J, Wang J, Yan X, Guo S, Wang M

Journal of Inflammation Research 2025, 18:16561-16578

Published Date: 26 November 2025

Mechanisms of Macrophage Polarization Regulated by Oridonin: A Review

Han Y, Zheng Z, Chen M, Xie K

Journal of Inflammation Research 2025, 18:16545-16560

Published Date: 26 November 2025

Chronic Inflammation in Patients with Chronic Coronary Syndrome Who Have Been Taking Lipid-Lowering Drugs as a Residual Risk Factor – a Bidirectional Synergistic Correlation with Epicardial Adipose Tissue

Zhu R, Wang W, Gao Y, Li B, Wang W, Liu J, Wu L, Yang S, Wang X

Journal of Inflammation Research 2025, 18:16531-16544

Published Date: 26 November 2025

Utility of Magnetic Resonance Imaging in Assessing Disease Activity in Axial Spondyloarthritis Regardless of C-Reactive Protein Status

Chen J, Huang Y, Huang H, Rui H, Zheng Q

Journal of Inflammation Research 2025, 18:16519-16529

Published Date: 26 November 2025

Correlation Between Red Blood Cell Distribution Width to Albumin Ratio and Cardiovascular Events in Maintenance Hemodialysis Patients

Guo H, Chen F, Zeng C, Wang Y, Ding M, Zhang N, Wu X, Wang X

Journal of Inflammation Research 2025, 18:16509-16518

Published Date: 26 November 2025

Potential Targets and Mechanisms of Saikosaponin D in Psoriasis: A Bioinformatic and Experimental Study on Oxidative Stress

Ding J, Sun A, Hu H, Li J, Lu S, Song J, He J, Song X, Qian S, Tian Z

Journal of Inflammation Research 2025, 18:16487-16507

Published Date: 26 November 2025

Advances in Necrotizing Fasciitis Animal Models: Current Trends and Future Perspectives

Li J, Huang C, Huang W, Zhou X, Wu Y, Li Y, Yang X

Journal of Inflammation Research 2025, 18:16473-16486

Published Date: 26 November 2025

Syndrome Differentiation and Treatment of Psoriasis by Traditional Chinese Medicines: An Integrating Study of Multi-Omics Analysis and Experimental Validation

Li C, Chen K, Qiao Y, Wu P, Chen C, Zhou L, Yang Y, Zhang J, Liu N, Shen C, Zhang G, Wang D, Gu J

Journal of Inflammation Research 2025, 18:16449-16472

Published Date: 26 November 2025

Novel Perspectives in Hepatic Ischemia-Reperfusion Injury: The cGAS-STING Pathway

Chen R, Yang T, Jiang Z, Long Y, Qian B, Fu W

Journal of Inflammation Research 2025, 18:16427-16448

Published Date: 24 November 2025

Multi-Omics Reveal That Gut Microbial Dysbiosis Drives Lipid Metabolic Disturbances and Inflammation in Gestational Hypertension

Tian S, Liu Y, Yang H, Chen K, Li J, Chen L, Wu T, Zhang L

Journal of Inflammation Research 2025, 18:16411-16425

Published Date: 24 November 2025

Comparison of Radiomics and Deep Learning Using Intestinal Ultrasound Images for Differentiating Inflammatory and Fibrotic Intestinal Strictures in Crohn’s Disease

Zhou R, Shi J, Qin J, Xue X, Zhou W, Zhao X, He X, Ma L, Zhou M, Guo C, Bai X, Zhu Q, Yang H

Journal of Inflammation Research 2025, 18:16399-16410

Published Date: 24 November 2025

Emerging Role and Function of Th9 Cells in Allergic Inflammation

Kaminuma O, Kitamura N, Gotoh M

Journal of Inflammation Research 2025, 18:16385-16397

Published Date: 22 November 2025

MFG-E8 in Kawasaki Disease: Role in Endothelial Injury and Diagnostic Potential

Pei Q, Zhang J, Li M, Yang P, Jing F, Yi Q

Journal of Inflammation Research 2025, 18:16365-16383

Published Date: 21 November 2025

Acupotomy Alleviates Capsular Fibrosis in Frozen Shoulder Rats by Modulating CCL2 to Inhibit Macrophage Recruitment and Suppress the Inflammatory Response

Liang H, Li J, Qiu S, Guo J, Liu J

Journal of Inflammation Research 2025, 18:16347-16364

Published Date: 21 November 2025

Original Research

Onco-inflammation

Prognostic Significance of Systemic Immune-Inflammation Index in Patients with de Novo non‑M3 Acute Myeloid Leukemia

Nan H, Yang P, Wang L, Li W, Liu Y, Huang F, Xu F, Shi M, Bai Y

Journal of Inflammation Research 2025, 18:16331-16346

Published Date: 21 November 2025

Original Research

Dermatological Inflammation

Dysbiosis of the Saliva Microbiota in Patients with Psoriasis: A Case-Control Study

Nielsen AB, Kvist-Hansen A, Todberg T, Zachariae C, Pedersen O, Skov L

Journal of Inflammation Research 2025, 18:16315-16330

Published Date: 20 November 2025

PCK2, a SASP-Associated Gene, Serves as an Independent Prognostic Indicator in Diffuse Large B-Cell Lymphoma

Chen M, Pan Y, Zhang J, Zeng Y

Journal of Inflammation Research 2025, 18:16293-16313

Published Date: 20 November 2025

Single-Cell Transcriptomics Reveals CCL3+ Classical Monocyte Subset Linked to Autoimmune Pathogenesis

Xu H, Yuan K, Chen G, Luo J, Yan A, Huang H, Yu X, Tao Q, Huang G, Xu A

Journal of Inflammation Research 2025, 18:16273-16291

Published Date: 20 November 2025

Potato Peel Extract Reduces MMP-9 Expression During Oral Mucosal Wound Healing in Rats

Sufiawati I, Finita N, Hidayat W, Yuslianti ER

Journal of Inflammation Research 2025, 18:16261-16272

Published Date: 19 November 2025

Characterization of a Long-Acting Anti-Human MASP-2 Antibody for the Treatment of Complement-Related Diseases

Han X, Yang C, Wang Z, Fan K, Liu K, Ye H, Zhang W, Zhang J, Hu X, Lin H, Liao C

Journal of Inflammation Research 2025, 18:16247-16260

Published Date: 19 November 2025

SIRT1 Enhancement is Required for the Induction of Anti-Inflammatory Effect of Micheliolide in Carbon Tetrachloride Induced Liver Fibrosis in Mice

Jin C, Jiang A, Chang J, Hu Y, Wang Y, Zhao R, Shi J, Wu H, Han Z, Liu Z

Journal of Inflammation Research 2025, 18:16231-16245

Published Date: 19 November 2025

Integrative Bulk and Single-Cell Transcriptome Analyses Reveal Mitochondrial Metabolism-Related Biomarkers in IgA Nephropathy with Experimental Validation

Wajid I, Nie X, Liu H, Li D, Ren Y, Wang Q

Journal of Inflammation Research 2025, 18:16209-16230

Published Date: 19 November 2025

Original Research

Respiratory Inflammation

Effects of Eosinophilopoietins and C-C Chemokines on Chemotaxis, Adhesion, and ROS Production of Blood Eosinophil Subtypes in Asthma Patients

Rimkunas A, Januskevicius A, Vasyle E, Kalinauskaite-Zukauske V, Palacionyte J, Miliauskas S, Malakauskas K

Journal of Inflammation Research 2025, 18:16187-16207

Published Date: 19 November 2025

Astragaloside IV Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis via the p53/SLC7A11/GPX4 Axis

Tang Z, Cheng L, Li M, Chen J, Huang C

Journal of Inflammation Research 2025, 18:16169-16186

Published Date: 19 November 2025

Nicotine Attenuates Chondrocyte Inflammation via the α7nAChR-Mediated Inhibition of the HMGB1/TLR4/NF-κB Signaling Pathway

Lin S, Liu T, Song G, Pan H

Journal of Inflammation Research 2025, 18:16157-16168

Published Date: 19 November 2025

Cross-Disease Identification of FBP1 in Atherosclerosis and Calcific Aortic Valve Disease via Integrated Bioinformatics and Validation: Functional Analysis and Therapeutic Target Exploration

Xu H, Xu Y, Wang X, Yan Z, Geng T, Wu J, Li Y, Guo M

Journal of Inflammation Research 2025, 18:16135-16156

Published Date: 19 November 2025

Original Research

Predictors of Abdominal Pain Duration in Henoch–Schönlein Purpura and Nomogram Model Development: A Retrospective Study of 220 Cases

Huang H, Chen X, Pan Y, Zhang Y, Yu R, Chen A

Journal of Inflammation Research 2025, 18:16123-16134

Published Date: 19 November 2025

Elevated ITGAV Expression in Seropositive Rheumatoid Arthritis: Diagnostic Potential and Immunopathological Insights

Shan Y, Zhao J, Li Y, Zheng Y, Shi Y, Zhao F, Cheng Y, Song C, Chang C, Hu H, He D

Journal of Inflammation Research 2025, 18:16111-16121

Published Date: 19 November 2025

Mechanistic Insights Into the Modulation of Gut Microbiota and ERK Signaling by Morusin in Juvenile Rats with Post-Infectious Cough

Luo J, Zhang D, Zhang M, Chen Y, Ding Y

Journal of Inflammation Research 2025, 18:16093-16109

Published Date: 19 November 2025

Predicting Risk of Post-Treatment Relapse in Patients with Inflammatory Bowel Disease Based on Intestinal Microbiota

Zhang T, He B, Lan C, Liu J, Zeng Q, Pu W, Zhou L, Zhou Q, Hu D, Chen Y, Peng Y, Li G, Wang Q, Chen L, Du Z, Li S, Tang X, Chen J, Xiao C

Journal of Inflammation Research 2025, 18:16079-16092

Published Date: 19 November 2025

Inflammation Promotes Insulin Resistance: Analysis Based on Inflammation Indices Obtained from the Complete Blood Count

Zhang X, Wei Y, Wang Y, Wang G, Liu J

Journal of Inflammation Research 2025, 18:16065-16077

Published Date: 18 November 2025

Comments on “Temporal Relationship Between Visceral Fat and Inflammation, and Their Joint Effect on Cardiometabolic Diseases: Evidence from the China Health and Retirement Longitudinal Study (CHARLS)” [Letter]

Zhang Z

Journal of Inflammation Research 2025, 18:16063-16064

Published Date: 17 November 2025

Metabolic Reprogramming Intermediates of Glucose Regulate Macrophage Polarization: An Important Direction for Ameliorating Pulmonary Vascular Remodeling

Wang J, Yuan R, Zhang S, Xu Z, Song L

Journal of Inflammation Research 2025, 18:16045-16062

Published Date: 17 November 2025

Anesthesia-Induced Ferroptosis: Bidirectional Regulation and Molecular Mechanisms in Cardio-Cerebral Injury

Chen Y, Ouyang J, Zhao W, Cheng L, Ye X, Hu Y, Si Y, Niu Q, Zhang H, Qiao Q, Zhang J

Journal of Inflammation Research 2025, 18:16023-16043

Published Date: 17 November 2025

Association Between Maternal IBD-Related Antibodies and Early Life Gut Inflammatory Status and Microbiota Composition: Insights from Cord Blood

Kim T, Nicoletti P, Estevinho MM, Tarassishin L, Picker M, Debebe A, Nguyen I, Dutra-Clarke R, Young C, Stone J, Bar-Gil Shitrit A, Agrawal M, Colombel JF, Torres J, Ng SC, Zhang L, McGovern DPB, Peter I

Journal of Inflammation Research 2025, 18:16009-16022

Published Date: 18 November 2025

High-Dose Corticosteroids in Critically Ill COVID-19 Patients: A Retrospective Cohort Study from Suriname

Daenen K, Neus A, Woittiez L, Bansie R, Nierich A, Huijben JA, Endeman H, van Gorp EC, Bihariesingh-Sanchit R

Journal of Inflammation Research 2025, 18:15995-16008

Published Date: 17 November 2025

Diagnostic Value of Long Non-Coding RNA NORAD in Acute Coronary Syndrome: A Diagnostic Biomarker Study

Xin W, Li Q, Deng X, Li R, Wang P

Journal of Inflammation Research 2025, 18:15985-15994

Published Date: 17 November 2025

Efficacy Analysis of a 12-Cytokine Panel for the Diagnosis of Kawasaki Disease and Prediction of Intravenous Immunoglobulin Resistance

Kong W, Gao L, Hu J, Xu Z, Zhang Q, Wang Y, Fu S, Xie C, Gong F

Journal of Inflammation Research 2025, 18:15973-15983

Published Date: 17 November 2025

Utilizing MRI Radiomics and Clinical Features to Predict Severe Acute Pancreatitis in Patients with Metabolic Syndrome

Wang Y, Wan X, Zhang Y, Liu Z, Liu Z, Tang M, Huang X

Journal of Inflammation Research 2025, 18:15959-15971

Published Date: 15 November 2025

Identification of Shared Diagnostic Biomarkers LCN2 and DUOX2 for Inflammatory Bowel Disease and Cholangiocarcinoma Through Integrative Bioinformatics and Machine Learning

Yuan S, Hu Z, Xu Z, Qian J, Wang X

Journal of Inflammation Research 2025, 18:15939-15958

Published Date: 14 November 2025

Time-Dependent Mortality Predictors in Primary Sjögren’s Syndrome: C-Reactive Protein for Early Risk and Age for Late Outcomes

Chen JQ, Zhang Y, Huang ZW, Yang JY, Liao JH, Lei CX, Zhang XY, Yu XB, Wu TH, Liu ZH, Tang BJ, Zhou XY, Deng TT, Luo J, Song WJ, Tao QW

Journal of Inflammation Research 2025, 18:15925-15937

Published Date: 14 November 2025

Sex Differences and Androgen Regulation Shape Mucosal Immune Phenotype, Gut Microbiota, and Microbiota-Derived Lactate in SKG Arthritis Model

Wu X, Jiang L, Cao Y, Wang P, Wang W, Zhang X

Journal of Inflammation Research 2025, 18:15911-15924

Published Date: 14 November 2025

The Intestinal Immune Network for IgA Production is Involved in the Development and Progression of Sepsis: A Multi-Omics Study

Wang YF, Gao S, Gao F, Wu ML, Yang L, Zhang JY, Wang YN, Xu HY

Journal of Inflammation Research 2025, 18:15887-15910

Published Date: 13 November 2025

Abnormal Alterations in EEG Microstates and Functional Networks in Anti-LGI1 Antibody Encephalitis

Wang L, Jiang P, Wang Y, Sun D, Miao A, Wang X

Journal of Inflammation Research 2025, 18:15875-15886

Published Date: 12 November 2025

Pyoderma Gangrenosum and Inflammatory Bowel Disease: Recent Insights into Epidemiology, Pathogenesis, and Therapeutic Approaches

Downey K, Zhang R, Ortega-Loayza AG

Journal of Inflammation Research 2025, 18:15859-15873

Published Date: 12 November 2025

Threshold Effect of the Lymphocyte to HDL-C Ratio on the Risk of Stroke-Associated Pneumonia After Acute Ischemic Stroke: A Retrospective Cohort Study

Li X, Du H, Zhang G, Song Z, Qi M, Wang H

Journal of Inflammation Research 2025, 18:15847-15858

Published Date: 13 November 2025

A Correlational Study on CALLY Index as a Potential Predictive Indicator for Postoperative in-Hospital Mortality in Acute Aortic Dissection Patients

Zhang H, Jiang F, Lin J, Yu X, Peng Y, Chen L, Lin Y

Journal of Inflammation Research 2025, 18:15833-15846

Published Date: 11 November 2025

The Correlation Study of Bone Metabolism and Inflammatory Markers with Major Adverse Cardiovascular Events in Patients with Obstructive Sleep Apnea Syndrome

Guo G, Xiao J, Chen J, Zhu C, Zhang Q, Li F

Journal of Inflammation Research 2025, 18:15817-15831

Published Date: 11 November 2025

Immune Microenvironmental Differences Between Obese and Healthy People in a High-Altitude Hypoxic Environment

Pu X, Wang Y, Lin X, Zhao J, Dai C, Ma Y, Shi P

Journal of Inflammation Research 2025, 18:15801-15815

Published Date: 11 November 2025

A Multicenter Study of Systemic Inflammatory Biomarkers for Prognostic Evaluation in iCCA Patients

Tao Y, Xu B, Tang J, Ji S, Li J

Journal of Inflammation Research 2025, 18:15787-15800

Published Date: 11 November 2025

Case report

Successful Treatment of Severe and Refractory Eosinophilic Pustular Folliculitis with Dupilumab: A Case Report with Two-Year Relapse-Free Follow-Up

Jiang X, Wu X, Chen S, Cheng H

Journal of Inflammation Research 2025, 18:15779-15785

Published Date: 11 November 2025

Stress-Induced Hyperglycemia as an Independent Predictor of Infectious Pancreatic Necrosis in Acute Pancreatitis: A Machine Learning-Driven Prognostic Model

Zhao X, Xu J, Hu C, Xue W, Che Z, Ling R, Chen H, Feng Y, Li X, Mo S, Tian Y

Journal of Inflammation Research 2025, 18:15761-15777

Published Date: 12 November 2025

Relationship Between the Level of CCL13 in Nasal Mucosa Tissue and Postoperative Recurrence in Patients with Chronic Rhinosinusitis

Zhao W, Li H, Jing F, Xiao S, Jia H, Chen H, Zhao W

Journal of Inflammation Research 2025, 18:15749-15760

Published Date: 11 November 2025

Relationship of the Specific Inflammatory Cytokines KLK5, IL-8, and IL-22 with Demodex Density and Risk Factors in Rosacea

Xu J, Zhang Y, Ci C, Lu X, Hu X, Zhao J, Li Y

Journal of Inflammation Research 2025, 18:15737-15748

Published Date: 11 November 2025

Repeated Mesenchymal Stem Cell Delivery Attenuates UHMWPE Wear Particle-Induced Osteolysis by Paracrine-Mediated Macrophage Reprogramming

Ding K, Fan D, Dong A, Ma C, Zeng T, Huang Z, Yang Y, Song K

Journal of Inflammation Research 2025, 18:15717-15735

Published Date: 11 November 2025

Histone Lactylation as an Epigenetic Regulator in Alzheimer’s Disease Pathophysiology: A Narrative Review

Tang J, Zhang Y, Wang Y, Fu Y, Qi J, Xiang A, Zhao R, Tan G, Deng H, Zhou X, Wu L

Journal of Inflammation Research 2025, 18:15701-15716

Published Date: 11 November 2025

Hydroxysafflor Yellow A Reduced Neuroinflammation Induced by Astrocyte-Derived IL-17A by Inhibiting the IL-17RA/ACT1/NF-κB/IL-17A Loop After OGD/R

Song L, Hua J, Liu K, Duan Y, Sun Y, Yu J, Yin J, Ma C, Xiao B, Ma D, Huang J

Journal of Inflammation Research 2025, 18:15687-15699

Published Date: 11 November 2025

Functions of Macrophages, T Cells, and Neutrophils in the Synovial Microenvironment of Osteoarthritis

Wen P, Liu L

Journal of Inflammation Research 2025, 18:15671-15686

Published Date: 11 November 2025

Current Insights and Future Perspectives for the Use of Serological Biomarkers in Polymyalgia Rheumatica

Harkins P, Cowley S, Conway R

Journal of Inflammation Research 2025, 18:15657-15670

Published Date: 10 November 2025

Metabolomic Profiling by UPLC-QTOF/MS Reveals Potential Biomarkers and Metabolic Alterations in Pediatric Septic Shock

Xiao C, Wang C, Wang S, Xu F, Chen Y

Journal of Inflammation Research 2025, 18:15645-15655

Published Date: 11 November 2025

Prognostic Value of Systemic Inflammation Scores in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: A Prospective Cohort Study

Wang X, Wang L, Qi Y, Liu Y, Zhang Y, Song G, Sun Q, Wei C, Liu J, Shi F, Sun L

Journal of Inflammation Research 2025, 18:15627-15643

Published Date: 8 November 2025

The Predictive Value of the Neutrophil Percentage-to-Albumin Ratio for Early Recurrence of Atrial Fibrillation After Radiofrequency Catheter Ablation

Nie L, Nie Q, Liu K, Zhang S, Wang Y, Yu Y, Feng W, Chen Y

Journal of Inflammation Research 2025, 18:15615-15626

Published Date: 8 November 2025

New Bitongling Ameliorates Joint Tissue Damage in Collagen-Induced Arthritis Mice by Suppressing Mapt Expression: A Genome-Wide Sequencing Study

Guo Y, Tian M, Liu Y, Ma J, Li Y, Hou Y, Wang Y

Journal of Inflammation Research 2025, 18:15597-15614

Published Date: 8 November 2025

The Association Between Phenotypic Age and Primary Loss of Response to Biologic Agent in Patients with Crohn’s Disease

Chen X, Liu J, Zhang Y, Wang Y, Chen X, Zhao Q

Journal of Inflammation Research 2025, 18:15587-15595

Published Date: 7 November 2025

Review

Monoamine Oxidase B in Cancers: Implications for Therapeutics and Prognosis

Liu Y, Li D, Xie C, Pan Y, Shi Q

Journal of Inflammation Research 2025, 18:15555-15586

Published Date: 8 November 2025

Prognostic Impact of Metabolic and Inflammatory Risk for Periprocedural MI and Long-Term Events in Three-Vessel Disease Patients

Song J, Liu Y, Zhou Q, Liu L, Yang X, Wang W

Journal of Inflammation Research 2025, 18:15543-15554

Published Date: 5 November 2025

Prognostic Value of C-Reactive Protein, Procalcitonin, and Interferon-Alpha in COVID-19 and Their Association with PANoptosis: A Cohort Study in Guangxi, China

Ning LJ, Liu MQ, Jiang ZS, Wu XQ, Wang XY, Qin XJ, Gan T, Tang SF, Lv GY, Wu Y

Journal of Inflammation Research 2025, 18:15527-15542

Published Date: 6 November 2025

Protective Effect of Xihuang Pill on Immune Checkpoint Inhibitors-Related Myocarditis in a Mouse Model by Regulating the HIF-1 Signaling Pathway

Cao B, Xie H, Xu J, Yu N, Man Z, Zhao W, Li G, Li C, Han L

Journal of Inflammation Research 2025, 18:15511-15525

Published Date: 7 November 2025

Prognostic Significance of C-Reactive Protein to Albumin Ratio in Predicting Long-Term Mortality Among Patients with Acute Heart Failure

Zuo R, Zhang J, Liu Q, Jia N

Journal of Inflammation Research 2025, 18:15501-15510

Published Date: 4 November 2025

Investigating Potential Biomarkers of Ankylosing Spondylitis: A Study on Mitochondrial and Senescence Pathways Using Machine Learning

Yang L, Chang C, Tam W, Liang Y, Chen M, Zhang J, Li K, Li Y, Gong Q

Journal of Inflammation Research 2025, 18:15479-15500

Published Date: 4 November 2025

Original Research

Effects of Advanced Glycation End Products (AGEs) on Human Lung Macrophages: Implications for Pulmonary Inflammation

Palestra F, Memoli G, Cristinziano L, Ferrara AL, Carucci L, La Rocca A, Illiano A, Modestino L, Poto R, Galdiero MR, Varricchi G, Spadaro G, Berni Canani R, Marone G, Mercadante E, Loffredo S

Journal of Inflammation Research 2025, 18:15463-15477

Published Date: 5 November 2025

Retinoic Acid-Loaded Cartilage Organoids Attenuate Chondrocyte Senescence in Osteoarthritis

Xi L, Chen Y, Luo Z, Zhang D

Journal of Inflammation Research 2025, 18:15441-15461

Published Date: 4 November 2025

Original Research

Glycochenodeoxycholic acid induces the release of IL-1beta from L02 cells via the NLRP3/caspase-1/GSDMD pathway to activate LX2 cells

Li J, Han L, Feng S, Lin G, Zou G, Huang T, Ran T, Zhao X

Journal of Inflammation Research 2025, 18:15429-15440

Published Date: 5 November 2025

Original Research

ICAM1-Mediated Endothelial Cells and Macrophage Interactions in Modulating GBM Malignant Transformation

Li J, Liang T, Liang B, Kang X, Wu W, Wang H, Yang H, Wang Y, Ma W

Journal of Inflammation Research 2025, 18:15409-15427

Published Date: 5 November 2025

Prognostic Value of Inflammatory and Nutritional Markers in Advanced Esophageal Squamous Cell Carcinoma Treated with Immunotherapy: A Retrospective Cohort Study

Liu X, Ren S, Li X, Cheng X, Fang Y, Zhang S, Zhao Y, Ma W, Zhang T

Journal of Inflammation Research 2025, 18:15393-15408

Published Date: 4 November 2025

Construction of a Risk Score Model for Predicting Airway Management in Maxillofacial and Neck Region Space Infections Using Inflammatory Markers

Wang X, Shi H, Qian W, Zhou Q, Wang B, Zhang W, Li H, Zheng L

Journal of Inflammation Research 2025, 18:15379-15392

Published Date: 4 November 2025

Network Pharmacology Combined with Animal Experiments Elucidates the Mechanism of Effect of Xin’an Formula in Treating Allergic Rhinitis

Zhang M, Song R

Journal of Inflammation Research 2025, 18:15357-15378

Published Date: 3 November 2025

Age-Stratified Risk Factors for Coronary Thrombosis in Kawasaki Disease Patients with Medium-to-Large Coronary Artery Aneurysms

Huo J, Peng Y, Guo P

Journal of Inflammation Research 2025, 18:15349-15355

Published Date: 4 November 2025

P300-Targeted Acetylome Reveals a Role for HMGB1 Translocation in Central Cardiac Sympathetic Activation Post Myocardial Infarction

Yin J, Liu F, Xia H, Yan S, Wang Y, Li X, Shi Y, Wang Y, Jing Y, Li Y, Hu H

Journal of Inflammation Research 2025, 18:15329-15347

Published Date: 4 November 2025

The Alterations in the Osteoimmune Microenvironment of STZ-Induced Type 2 Diabetic Mice:A Single-Cell RNA Sequencing Analysis

Han K, Yan SG, Liu F, Li L, Zhou D, Li L, Liu N, Dong J

Journal of Inflammation Research 2025, 18:15309-15327

Published Date: 4 November 2025

Original Research

Dermatological Inflammation

Kushe Tincture Ameliorates DNCB-Induced Atopic Dermatitis by Affecting NF-Kb/JAK-STAT3 Pathway: Bioinformatics Analysis and Animal Experiment Verification

Feng H, Zhou Y, Ren X, Zhu X, Duan X, Qu S, Zhu B, Li Y, Qin Y

Journal of Inflammation Research 2025, 18:15293-15308

Published Date: 4 November 2025

Do Inflammatory and Nutritional Markers Predict Prognosis in Metastatic Non-Small Cell Lung Cancer Patients Receiving Nivolumab

Zeynelgil E, Çağlayan D, Çelik S, Ayyıldız Sevim H, Şahinli H, Karakaya S, Eren T

Journal of Inflammation Research 2025, 18:15283-15292

Published Date: 4 November 2025

Comment on “Association Between Triglyceride-Glucose Index and Malignant Risk in Thyroid Nodules: A Cross-Sectional Analysis” [Letter]

Hu Z, Dong H, Fei Y

Journal of Inflammation Research 2025, 18:15281-15282

Published Date: 4 November 2025

Tumor-Associated Macrophages in Lung Cancer: Origins, Functional Heterogeneity, and Therapeutic Implications

Tao Y, Xiao J, Li Y, Zou A

Journal of Inflammation Research 2025, 18:15257-15280

Published Date: 31 October 2025

Immune Landscape in Kidney Transplantation

Niu D, Chen R, Pang X

Journal of Inflammation Research 2025, 18:15237-15256

Published Date: 30 October 2025

The Role of Mitochondrial Dysfunction and Inflammatory Response in the Pathogenesis of Sepsis-Induced Myocardial Injury: A Mechanistic Study

Liu AB, Wang S, Shen Y, Ma L, Zhang JF

Journal of Inflammation Research 2025, 18:15207-15235

Published Date: 30 October 2025

Role of Monocyte/Macrophage-Associated Gene Ccl9 in Acute Myocardial Infarction Analysis: Based on Bulk and Single Cell RNA Sequencing Data

Yang Q, Luo Z, Cheng X, Wang T, Hu P

Journal of Inflammation Research 2025, 18:15187-15206

Published Date: 31 October 2025

Integration of Network Pharmacology, Molecular Docking, and Experimental Validation to Identify the Effect of EGCG on Alleviating Chondrocyte Inflammatory Damage by Targeting ER Stress-STAT3 Crosstalk

Zhao MJ, Yin JL, Luo JH, Ge YS, Huang CM, Meng TT, Wang XZ, Huang XH, Chen LL, Zhai YQ, Wu XB, Ding DF

Journal of Inflammation Research 2025, 18:15165-15185

Published Date: 30 October 2025

Serum IL-1β as a Novel Predictor of No-Reflow in STEMI Patients Undergoing Primary PCI

Wang S, Wang H, Huang Y, Zhu J, Cheng Q, Gao C

Journal of Inflammation Research 2025, 18:15153-15164

Published Date: 31 October 2025

Banxia-Xiexin Decoction Ameliorates Colitis-Associated Colorectal Cancer by Modulating Inflammatory Responses and the Complement and Coagulation Cascade Pathway

Chen Q, Wang M, Shi W, Liu Y, Wang L, Zhao Y, Qiu Z, Qiu Y, Dong X

Journal of Inflammation Research 2025, 18:15135-15151

Published Date: 30 October 2025

SCAP/SREBP2-Mediated Cholesterol Biosynthetic Pathway Suppresses Particulate Matter-Induced Macrophage Activation and Airway Inflammation

Chen WS, Lou JF, Li JY, Wu YP, Gao SW, Zheng K, Huang JQ, Li M, Zhu C, Zhang SY, Chen ZH, Wu YF, Li W

Journal of Inflammation Research 2025, 18:15117-15133

Published Date: 29 October 2025

Original Research

Bioinformatics and Experimental Validation of FLVCR1 and SOX4 in Regulating Mitochondria-Macrophage Crosstalk in Disc Degeneration

Zhou J, Zheng Y, Zheng X, Chen CY, Ding SC, Wang R

Journal of Inflammation Research 2025, 18:15101-15116

Published Date: 30 October 2025

Protective Effects of Irisin Against LPS-Induced Intestinal Injury and Its Influence on Gut Microbiota in Septic Mice

Yang L, Liu M, Hu B, Yong K, Zhou J, Chen Y

Journal of Inflammation Research 2025, 18:15081-15100

Published Date: 29 October 2025

Role of Pyroptosis in the Pathogenesis of Osteoarthritis: An Updated Review

Yang F, Li D, Long W, Li E, Wei B

Journal of Inflammation Research 2025, 18:15065-15079

Published Date: 29 October 2025

Emerging Allergens: How Proallergenic Activity Disrupts Epithelial Barriers [Response to Letter]

Sztandera-Tymoczek M, Wdowiak-Wróbel S, Świderska U, Palusińska-Szysz M, Szuster-Ciesielska A

Journal of Inflammation Research 2025, 18:15063-15064

Published Date: 29 October 2025

Baseline Expanded Disability Status Scale Score and CD8+ T Cell Levels as Risk Factors for Disability Progression in Multiple Sclerosis

Liu PJ, Yuan P, Liu SP

Journal of Inflammation Research 2025, 18:15049-15061

Published Date: 29 October 2025

METTL3/IGF2BP2-Mediated m6A RNA Methylation Drives Alveolar Macrophage-Dependent Neutrophil Recruitment in Cigarette Smoke-Induced COPD

Lin A, Wang J, Wang L, Zhang Y

Journal of Inflammation Research 2025, 18:15033-15047

Published Date: 29 October 2025

Succinate’s Dual Roles in Inflammatory Bowel Disease: A Narrative Review of Microbiota-Metabolism-Immune Crosstalk and Therapeutic Implications

Zhao M, Zhou C, Wang D, Wu Q, Feng B

Journal of Inflammation Research 2025, 18:15017-15032

Published Date: 28 October 2025

Interpretable Machine Learning Model for Early Mortality Prediction in Septic Patients Using Routine Post-Diagnosis Clinical Data: A Multicenter Study

Sun W, Zhang L, Mou D, Zhao B, Che Z, Li Y, Wang S

Journal of Inflammation Research 2025, 18:15003-15015

Published Date: 28 October 2025

The Dual Role of Nitric Oxide in Allergic Rhinitis: From the NO/cGMP Signaling Pathway to Possible New Therapeutic Targets for Organelle Damage

Wang W, Wang L, Lin H

Journal of Inflammation Research 2025, 18:14989-15001

Published Date: 27 October 2025

Identification of SIN3A as a Promising Epigenetic Target Against Allergic Rhinitis

Li H, Wang R, Yu B, Zeng J, Xiao Z

Journal of Inflammation Research 2025, 18:14971-14987

Published Date: 27 October 2025

Review

Dermatological Inflammation

Mechanisms Underlying Lichen Planus in Association with Biologic Therapy

Podolsky AS, Lipner SR

Journal of Inflammation Research 2025, 18:14961-14970

Published Date: 27 October 2025

Platelet Hyperactivation Plays a Critical Role in Exacerbating Skin Lesions in Rats with Psoriasis and Blood Stasis Syndrome

Yue H, Mo H, Su H, Zeng Z, Liu F, Lei C, Sun Y, Wang T, Pi X, Li L, Wu J, Han L

Journal of Inflammation Research 2025, 18:14941-14959

Published Date: 27 October 2025

Lactate Dehydrogenase-to-Albumin Ratio as a Predictor of In-Hospital Mortality in Predicted Severe Acute Pancreatitis: Evidence from an 18-Year Cohort Study

Zou Y, Kuang M, Xiong S, Xu X, Li X, Ding L, He C, Li N, Ke H, Huang X, Lei Y, Xiong H, He W, Xia L, Lu N, Wan J, Zhu Y

Journal of Inflammation Research 2025, 18:14927-14939

Published Date: 27 October 2025

Temporal Relationship Between Visceral Fat and Inflammation, and Their Joint Effect on Cardiometabolic Diseases: Evidence from the China Health and Retirement Longitudinal Study (CHARLS)

Lin M, Zhou Y, Wu R, Li S, Ni X, Xiao J, Han S, Tang H, Huang J, Wen J, Jiang L, Tan X, Chen Y

Journal of Inflammation Research 2025, 18:14913-14926

Published Date: 27 October 2025

Lactylation-Related Gene CALM1 Promotes Aortic Dissection via Immune Microenvironment Remodeling: Insights from Bioinformatics and Clinical Evidence

Yu Z, Pan Y, Qian X, Zhang X, Zhu Z, Xue Q, Xiao W

Journal of Inflammation Research 2025, 18:14891-14911

Published Date: 27 October 2025

Interleukin-31 in Respiratory Type 2 Inflammatory Diseases: Mechanistic Insights and Therapeutic Potential

Yao S, Zhao Y, Li Z, Lou H, Zhang L

Journal of Inflammation Research 2025, 18:14881-14890

Published Date: 27 October 2025

Relationship Between Inflammation-Nutrition Composite Indices and Ovarian Endometrioma: A Retrospective Observational Study

Zhang Y, Zeng NM, Fan JY, Qiu JP, Jiang FD, Wang Y

Journal of Inflammation Research 2025, 18:14871-14880

Published Date: 27 October 2025

Investigating the Role of Salidroside in Alleviating Acute Pancreatitis by Inhibiting the RIPK1/RIPK3/MLKL Pathway-Mediated Necroptosis in Pancreatic Acinar Cells in Rats

Lin Y, Ma X, Zhang L, Gu H, Fu X, Li P

Journal of Inflammation Research 2025, 18:14857-14869

Published Date: 27 October 2025

OPG and TNFR1 as Potential Biomarkers of Inflammation in Older Adults with Acute COVID-19 and Indicators of Frailty in Post-COVID-19: A Pilot Study

Ramon-Luing LA, Flores-Gonzalez J, Cataneo-Piña DJ, Falfán-Valencia R, Pérez-Rubio G, Buendia-Roldan I, Selman M, Chavez-Galan L

Journal of Inflammation Research 2025, 18:14841-14855

Published Date: 25 October 2025

The Value of Dynamic of Alkaline Phosphatase and Neutrophil-to-Lymphocyte Ratio in Predicting the Efficacy of Neoadjuvant Immunochemotherapy in Patients with Non-Small Cell Lung Cancer

Gong L, Yan Q, Liang D, Li L, Yang J, Wong W, Zhang S, Dai S, Zhai W, Wang J

Journal of Inflammation Research 2025, 18:14827-14839

Published Date: 25 October 2025

Changes in Plasma Growth Differentiation Factor-15 After Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients: A Prospective Study [Corrigendum]

Salman A, Shaaban HED, Salman M, M Seif El Nasr S, Soliman A, Salem A, Tag El-Din M, Mikhail HMS, El Domiaty H, Abd Allah N, GabAllah GMK, Youssef A

Journal of Inflammation Research 2025, 18:14825-14826

Published Date: 25 October 2025

Identification and Validation of Lipid Metabolism-Related Biomarkers GPD1 and CEBPD in Metabolic Dysfunction-Associated Steatohepatitis

Zhou J, Xiao C, Huang B, Chen F

Journal of Inflammation Research 2025, 18:14805-14823

Published Date: 25 October 2025

The Relationship Between IL-6 and IL-10 Expression Levels and the Prognosis in B-Cell Non-Hodgkin Lymphoma Patients Treated with R-CHOP

Dong Q, Lin W, Yu S, Qin Y, Jia C, Wang N, Xiu W, Shan W, Dong M, Liu D

Journal of Inflammation Research 2025, 18:14791-14804

Published Date: 25 October 2025

Novel Inflammatory Markers and Their Association with the Severity of Hypertriglyceridemia-Associated Acute Pancreatitis

Zhong L, Ding J, Chen M, Cai X, Chen L, Du X, Rao Y, Zhang D

Journal of Inflammation Research 2025, 18:14771-14790

Published Date: 24 October 2025

TIMP4 as a Potential Complementary Biomarker and Therapeutic Target in Membranous Nephropathy: A Multi-Omics Investigation with Clinical Validation

Chen Q, Wang G, Zhao R, Hu Q, Li J, Wang Y, Ran J, Huang Q, Yu G, Luo Y, Liao X

Journal of Inflammation Research 2025, 18:14755-14769

Published Date: 25 October 2025

Macrophage-Derived Exosomal BMPR2 Mediates Alveolar Epithelial Repair and Cellular Crosstalk in Acute Lung Injury

Yun X, Li F, Chen Z, Meng J, Zhang L, Yuan J

Journal of Inflammation Research 2025, 18:14737-14753

Published Date: 25 October 2025

Ferroptosis-Related Gene CRYAB in Asthma: Bioinformatics Identification and Experimental Validation

Lei J, Guo Y, Gao F, Zhu H, Ma J, Zhao L

Journal of Inflammation Research 2025, 18:14721-14735

Published Date: 26 October 2025

Hemoglobin-Albumin-Lymphocyte-Platelet Score as an Integrative Biomarker for Prognosis and Sarcopenia in Colorectal Cancer

Xie H, Wei L, Tang S, Gan J

Journal of Inflammation Research 2025, 18:14709-14720

Published Date: 24 October 2025

Altered Iron Regulation and the Role of Ferritin Heavy Chain in Dermatomyositis Patients

Li Q, Cheng X, Zhou M, Ji N, Zhu S, Jiang J, Fang Q, Liu M

Journal of Inflammation Research 2025, 18:14697-14707

Published Date: 24 October 2025

The Function of the TGFβ Signaling Pathway in Connective Tissue Diseases: From Biology to Clinical Application

Yuan S, Zhu W, Wang Y, Yu L

Journal of Inflammation Research 2025, 18:14679-14696

Published Date: 24 October 2025

MALAT1’s m6A Modification by METTL3 Promotes Pyroptosis and Inflammation in Sepsis-Induced Acute Kidney Injury in Mice

Guo P, Deng G, Li L, Wei H, Gong Y, Tan Y, Ma Y

Journal of Inflammation Research 2025, 18:14663-14678

Published Date: 24 October 2025

Ineffective Recanalization and Complications in Patients with Acute Ischemic Stroke Receiving Endovascular Treatment: Predictive Value of the c-Reactive Protein-Albumin-Lymphocyte (CALLY) Index

Zhu L, Jie S, Wu S, Chen Q, Zhang X, Yang W, Wu Y

Journal of Inflammation Research 2025, 18:14649-14661

Published Date: 22 October 2025

Exploring Immunological Determinants and Constructing a Predictive Model for Diagnosis of Gout: Insights Into Immune Biomarkers

Zeng H, Zheng L, Wu D, Yu X, Zhang G, Du J

Journal of Inflammation Research 2025, 18:14629-14647

Published Date: 23 October 2025

Atorvastatin Alleviates Sepsis-Induced Cardiomyopathy by Targeting the METTL3/IGF2BP1/CXCL2 Pathway

Zhang L, Yin Y, Zheng L, Wang Y, Zhao J, Mu F, Jin F, Gong R, Wang J

Journal of Inflammation Research 2025, 18:14609-14628

Published Date: 21 October 2025

Potential Targets and Bioactive Constituents of Daying Decoction in Schizophrenia with Neuroinflammation: A Preliminary Exploratory Integrative Study

Guo L, Zhang B, Liu M, Qin Y, Lu H, Wang Z, Yuan Y, Zheng Q, Zhao G, Qiao Y, Ma R, Lu B, Li Y

Journal of Inflammation Research 2025, 18:14589-14608

Published Date: 22 October 2025

Yin-Hua Li-Shi Decoction Alleviated Atopic Dermatitis Through Regulating Th Cells Balance and Restoring Epithelial Barrier

Wu J, Tai Z, Zhu C, Li L, Liu J, Ma T, Yin B, Zhou H, Zhu Q, Chen Z

Journal of Inflammation Research 2025, 18:14569-14587

Published Date: 21 October 2025

Biomarker Quantification of Gut Dysbiosis-Derived Inflammation: A Review

Lin L, George J, Liu G

Journal of Inflammation Research 2025, 18:14551-14567

Published Date: 21 October 2025

Original Research

TP-P1-Loaded Thermosensitive Hydrogel Attenuates Rheumatoid Arthritis in a Mouse Model via TLR4/NF-κB Pathway

Wang F, Hu Z, Yang J, Li C, Zhang W, Wang C, Yu S, Li J, Zhao W, Chen B, Zhu X

Journal of Inflammation Research 2025, 18:14535-14549

Published Date: 21 October 2025

Review

Multiple Roles of Palmitic Acid in Cardiovascular Diseases

Jiang H, Na C, Zhu Y, Bi Y, Yang R, Yang R, Yang H, Niu M, Huang X, Yang J

Journal of Inflammation Research 2025, 18:14515-14533

Published Date: 21 October 2025

Prognostic Values of the Systemic Immune Inflammation Index and Ferritin Level Combined with Pathological Indicators for the Patients with Colon Cancer After Radical Resection

Wu Y, Wang W, Ye B, Zhu L

Journal of Inflammation Research 2025, 18:14503-14513

Published Date: 21 October 2025

Analysis of the Efficacy and Safety of Secukinumab Combined with Surgical Treatment for Hidradenitis Suppurativa: A Real-World Retrospective Study in China

Liu X, Yuan C, Kang Y, Zhang J, Li Y, Wang R, Ding C, Zhang J, Xing W

Journal of Inflammation Research 2025, 18:14493-14502

Published Date: 22 October 2025

Advances in the Understanding of Mitochondrial Inflammatory Regulation in the Pathogenesis of Alzheimer’s Disease

Zhang RZ, Li L, Ma C, Dou TT, Wei YT, Yan XK

Journal of Inflammation Research 2025, 18:14475-14491

Published Date: 23 October 2025

Serum miR-27a Reduction and FOXO3 Elevation in Elderly Patients with Severe Pneumonia Complicated with ARDS: Association with Disease Severity and Prognosis

Zhao P, Wang Z, Shi M, Zhou Y, Zhang Z, Fang X, Qu G

Journal of Inflammation Research 2025, 18:14465-14474

Published Date: 21 October 2025

Case report

Dermatological Inflammation

Dupilumab-Induced Generalized Lichen Planus: A Case Report

Feng HS, Zhang C, Guo Y, Jia YN, Zhai Y, Zheng XR, Zhang T, Zhu BC, Zhang WT, Hua GD

Journal of Inflammation Research 2025, 18:14457-14463

Published Date: 17 October 2025

Safe Use of Corticosteroids in Non-Infectious Uveitis

Belletti M, Izquierdo-Escamez R, Tornero C, Olivas-Vergara O, Peiteado D, Carreño E

Journal of Inflammation Research 2025, 18:14441-14455

Published Date: 17 October 2025

Emerging Allergens: How Proallergenic Activity Disrupts Epithelial Barriers [Letter]

Wei Y, Xie Z

Journal of Inflammation Research 2025, 18:14439-14440

Published Date: 17 October 2025

Original Research

Perampanel Regulates Neuroinflammation and Ferroptosis via Activating FSP1 Following Brain Ischemia

Lv JM, Pan YJ, Wang X, Zhang MM, Li W, Liu J, Wang T

Journal of Inflammation Research 2025, 18:14423-14437

Published Date: 17 October 2025

Crosstalk Between Keratinocytes and T Cells in Ulcerative Oral Mucosal Diseases: Mechanisms of Epithelial Dysfunction and Therapeutic Perspectives

Hao Y, Yuan Y, Yu Y, Liu C, Wang Z, Li Y, Chen Q

Journal of Inflammation Research 2025, 18:14405-14421

Published Date: 16 October 2025

Multi-Niche Microbial Profiling in Papillary Thyroid Carcinoma and Thyroid Nodules: Linking Oral, Gut, and Tissue Microbiota

Chang W, Kang L, Lan T, Zhou C, Pang B, Jiang X, Zhao Z

Journal of Inflammation Research 2025, 18:14391-14404

Published Date: 17 October 2025

N-Acetylcysteine as a Potential Immunomodulator in Tuberculosis: Evidence of IL-2 Elevation in a Pilot Study

Yudhawati R, Husodo S, Aini FN

Journal of Inflammation Research 2025, 18:14381-14390

Published Date: 16 October 2025

Isoorientin Modulates Gut Microbes and Their Metabolites to Alleviate Caco-2 Cell Monolayer Inflammation by Reducing Intestinal Permeability via P-Gp/eCBs

Wang Z, Jiang Y, Duan B, Zhang H, Li A, Yang J, Lv M, Yang J

Journal of Inflammation Research 2025, 18:14365-14379

Published Date: 16 October 2025

Construction of a Nomogram Model Based on the Pan-Immune-Inflammation Value for Prediction of Adverse Clinical Outcomes in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Weng S, Huang Y, Wu X, Chen Q

Journal of Inflammation Research 2025, 18:14353-14364

Published Date: 17 October 2025

Study on the Impact of Perioperative Application of Mindfulness - Based Motivational Care Combinations on Post - Operative Recovery and Negative Emotions of Endometriosis Patients

You Y, Luo Y, Li P

Journal of Inflammation Research 2025, 18:14343-14352

Published Date: 15 October 2025

Chronic Sleep Fragmentation Differentially Affects Alzheimer’s Disease Pathology in Male and Female APPSAA Knock-in Mice

Hawkins MR, Whitlock HR, Johnson CE, Macheda T, Cox MF, Lapid MG, Roberts KN, Hash HM, Drinkard EG, Sunderam S, O’Hara BF, Murphy MP, Duncan MJ, Bachstetter AD

Journal of Inflammation Research 2025, 18:14325-14341

Published Date: 16 October 2025

A Novel NPR48-Based Model for Early Prediction of Severe Acute Pancreatitis: Development and Multicenter Validation in Comparison with Traditional Clinical Scores

Gu K, Ye L

Journal of Inflammation Research 2025, 18:14307-14324

Published Date: 15 October 2025

Parishin Protects Against Sepsis-Induced Intestinal Injury by Modulating the ACSL4/p-Smad3/PGC-1α Pathway: An Integrated Approach of Bioinformatics and Experimental Validation

Bao D, Shao S, Wang Y, Chen X, Ren Y, Zhou C, Mao Q

Journal of Inflammation Research 2025, 18:14283-14305

Published Date: 15 October 2025

Pyroptosis-Related Genes as Prognostic Biomarkers and Immune Infiltration Features in Sepsis-Induced ARDS: A Single-Cell and Bulk RNA-Sequencing Analysis

Zhang P, Xu CL, Xu L, Wu JJ, Wang L

Journal of Inflammation Research 2025, 18:14261-14282

Published Date: 15 October 2025

Early Immune-Inflammatory Profiling and Prognostic Biomarkers in Patients with Acute Diquat Poisoning: A Multicenter Study with Exploratory Bioinformatics Analysis

Wang P, Lin LY, Song CY, Fang JJ, Zhang BW, Li WS, Yu HJ, Fu YP, Lu YQ

Journal of Inflammation Research 2025, 18:14245-14260

Published Date: 15 October 2025

Original Research

The Prognostic Value of Complete Blood Count-Derived Inflammatory Indicators for All-Cause Mortality in Type 2 Diabetes Mellitus: A Retrospective Cohort Study

Li B, Xu Y, Zhu H, He Q, Yin Q, Wu M, Zhang J, Cao YJ

Journal of Inflammation Research 2025, 18:14231-14244

Published Date: 15 October 2025

Comparison of Blood Inflammation Scores and Their Prognostic Value in Elderly Unresectable Esophageal Squamous Cell Carcinoma Patients Treated with Radiotherapy/Chemoradiotherapy

Zhang Y, Wang J, Cui D, Kong L, Wang P, Fu Z, Lin L, Tang C, Liang J

Journal of Inflammation Research 2025, 18:14217-14230

Published Date: 14 October 2025

Triglyceride-Glucose Index and Neutrophil-to-Lymphocyte Ratio: A Metabolic-Inflammatory Signature for Mortality Prediction in a Multicenter Retrospective Cohort of 1249 Dialysis Patients with Coronary Artery Disease

Li Y, Li P, Tang Q, Jiao T, Gao Y, An S, Jiang H, Cheng H, Yang Z, Zhou J, Sun Y, Yang Y, Zheng J

Journal of Inflammation Research 2025, 18:14203-14215

Published Date: 15 October 2025

Role of Autophagy Induced by Pmel17 in the Pathogenesis of Vitiligo

Sun L, Sun J, Feng Y, Zhu L, Li H, Xu C, Guo C

Journal of Inflammation Research 2025, 18:14185-14201

Published Date: 11 October 2025

A Case of Isolated Extramedullary Plasmacytoma of the Sternoclavicular joint: A Rare Case Report

Yan Y, Ouyang M, Han Y

Journal of Inflammation Research 2025, 18:14175-14184

Published Date: 11 October 2025

Revisiting Janus Kinase Inhibitors in Hospitalized COVID-19: Evidence for Baricitinib’s Superiority and the Absence of a Class Effect

Gu L, Lin J, Yue J, Liu Z, Huang JA

Journal of Inflammation Research 2025, 18:14171-14173

Published Date: 11 October 2025

Risk Factor Analysis for Recurrence of Subacute Necrotizing Lymphadenitis in Children

Wu Y, Wen Y, Long Y, Chen Y, Ding Y

Journal of Inflammation Research 2025, 18:14161-14170

Published Date: 10 October 2025

Combined Biomarker Panel of Presepsin, HE4, and Oxygenation Index for Sepsis Diagnosis and Prognosis in Intensive Care Unit Patients

Luo J, An S, Liao X, Wu J, Li L

Journal of Inflammation Research 2025, 18:14147-14159

Published Date: 10 October 2025

Emerging Insights into the Role of Macrophages in Multiple Sclerosis: Pathogenesis and Potential Therapeutic Strategies

Yang J, Fu Z, Zou Q, Li Z, Xing Y

Journal of Inflammation Research 2025, 18:14131-14146

Published Date: 10 October 2025

Original Research

The Pomegranate Peel Polyphenols Protects Acne Vulgaris by Regulating Inflammation Through Notch/NF-κB Signal Pathway

Wang Y, Zhu M, Wu S, Zhao D, Bai Q, Liu Y

Journal of Inflammation Research 2025, 18:14113-14129

Published Date: 10 October 2025

NLRP3 Inflammasome in Gynecologic Inflammatory Diseases: Mechanisms, Pathophysiology, and Therapeutic Strategies

Wang T, Zheng R, Qu Y, Shu P, Ai W, Zhao J, Liu L

Journal of Inflammation Research 2025, 18:14097-14112

Published Date: 10 October 2025

ZnO NPs Attenuate LPS-Induced Inflammation in RAW264.7 Macrophages by Inhibiting NF-κB and JAK1-STAT1/STAT3 Pathways and Reducing ROS

Tang H, Zhang L, Deng C, Li Y, Ren G, Sun Z, Chang L, Xu M, Xiao D, Zhang H

Journal of Inflammation Research 2025, 18:14075-14096

Published Date: 9 October 2025

Gut Microbiota and Metabolite Changes Induced by Tacrolimus: Implications for Skin Transplant Immunology in Mice

Wang J, Zhang X, Cui C, Li M, Xie Z, Yang L, Ding D, Li X, Zhao M

Journal of Inflammation Research 2025, 18:14059-14073

Published Date: 9 October 2025

Maresin 1 Alleviates Seizure Symptoms by Modulating the Crosstalk Between Inflammation and Ferroptosis

Liu Y, Xu S, Luo Y, Xiao X, Jiang X, Xiao W, Xie R, Deng X, Li Z, Cao Y, Chang Y, Wu D, Xu H, Zhao W

Journal of Inflammation Research 2025, 18:14039-14057

Published Date: 9 October 2025

Genetic Association and Drug Target Exploration Between Inflammation-Related Proteins and the Risk of Primary Ovarian Insufficiency

Wang C, Lin XH, Yang XJ

Journal of Inflammation Research 2025, 18:14023-14037

Published Date: 9 October 2025

Glyuranolide-Dependent Inhibition of NF-κB/Akt Pathways by Sini Decoction Enhances Caspase-3-Mediated Apoptosis in Colorectal Cancer

Shi L, Zhang L, Xu J, Guo B

Journal of Inflammation Research 2025, 18:14011-14021

Published Date: 8 October 2025

Prognostic Impact of Advanced Lung Cancer Inflammation Index (ALI) on Immunotherapy Outcomes in Recurrent or Metastatic Nasopharyngeal Carcinoma: A Multicenter Post Hoc Analysis

Xu S, Liu Z, Song G, Pei Y, He M, Ge J, Qing Y, Wei Y, Shao M

Journal of Inflammation Research 2025, 18:13999-14009

Published Date: 8 October 2025

Association of Preoperative Leukocyte-to-Albumin Ratio with Short- and Long-Term Outcomes After Valvular Heart Surgery: A Retrospective Cohort Study

Lin Y, Liao X, Li S, Yan X, Chen L, Lin Y

Journal of Inflammation Research 2025, 18:13985-13997

Published Date: 8 October 2025

Original Research

Apigenin Suppresses NLRP3 Inflammasome Activation and Pyroptosis and Promotes Functional Recovery by Promoting Mitophagy in Experimental Spinal Cord Injured Rats

Wu Z, Fang Y, Dong Y, Qin Y, Liu A, Han T, Song P, Shen C

Journal of Inflammation Research 2025, 18:13965-13984

Published Date: 8 October 2025

Paeoniflorin Attenuates Cognitive Dysfunction and Neuroinflammation by Autophagy in Mice with SLE Induced by Imiquimod

Ma T, Wang Q, Zhang L, Chen X, Fan Z, Wang Y, Zhang X, Huang Y, Lu X, Song P, Xie C, Xi J, Li B, Wang Y

Journal of Inflammation Research 2025, 18:13945-13964

Published Date: 7 October 2025

A Conceptual Review of Gut, Skin, and Oral Microbiota in Autoimmune Bullous Diseases: From Dysbiosis to Therapeutic Potential

Xu H, Li S, Liu S, Zuo YG

Journal of Inflammation Research 2025, 18:13925-13943

Published Date: 7 October 2025

Semaphorin 6D Alleviates Osteoarthritis by Inhibiting NLRP3 Inflammasome Activation and Endoplasmic Reticulum Stress

Zhang W, Li C, Yao J, Xu Z, Huang Y, Lu Y, Lin X, Guo Z, Zhou X

Journal of Inflammation Research 2025, 18:13909-13924

Published Date: 7 October 2025

Comment On: “Effectiveness of Combining Thoracic Paravertebral Nerve Block and Serratus Anterior Plane Block in Non-Intubated Spontaneous-Ventilation Video-Assisted Thoracoscopic Surgery: A Retrospective Case-Control Study” [Letter]

M Sethuraman R, Arulmozhi S, Babu A

Journal of Inflammation Research 2025, 18:13907-13908

Published Date: 8 October 2025

Original Research

Bowel Urgency in Ulcerative Colitis is Independently Associated with Histologic Inflammation and Stool Form Despite Endoscopic Remission

Wei ZH, Chen TD, Chou JW, Lin SH, Huang TY, Chang CW, Chiu CT, Chen CM, Kuo T, Su MY, Pan YB, Le PH

Journal of Inflammation Research 2025, 18:13897-13906

Published Date: 8 October 2025

Identification of Key Biomarkers and Immune Microenvironment Features in Ulcerative Colitis: An Integrated Analysis Using WGCNA and Multiple Machine Learning Algorithms

Qi Y, Wang Y, Zhang S, Pan X, Li W, Cheng M, Ma W, Li J, Pei Y, Liu Y, Yu Y

Journal of Inflammation Research 2025, 18:13879-13896

Published Date: 7 October 2025

Downregulation of Gbp2 Attenuates LPS-Induced Inflammation in BV2 Microglia Cells Through Inhibition of STAT1

Bao Y, Ni H, Wang K, Ma L, Gu J, Zhang X, Gao H, He G

Journal of Inflammation Research 2025, 18:13869-13877

Published Date: 6 October 2025

Significance of Residual Inflammatory Risk and Persistent Inflammation in Patients with Myocardial Infarction with Nonobstructive Coronary Arteries

Gao S, Huang S, Liu X, Yu M, Li W

Journal of Inflammation Research 2025, 18:13855-13868

Published Date: 6 October 2025

Original Research

Six Interferon-Stimulated Genes as Biomarkers of M1 Macrophage Polarization in Psoriasis

Wu S, Mao Y, Hu L, Ji H, Liu X, Ma G, Chen C, Xiao C, Xu D, Yang W

Journal of Inflammation Research 2025, 18:13835-13853

Published Date: 9 October 2025

Impact of Diabetes on Clinical Characteristics and Prognosis in Sepsis: A Retrospective Study

Han WW, Fang JJ

Journal of Inflammation Research 2025, 18:13823-13834

Published Date: 6 October 2025

Identifying Immuno-Fibrotic Roles of Lactylation-Related T Cell Hub Genes in Renal Ischemia–Reperfusion Injury: A Multi-Omics Study and Experimental Validation

Qiu X, Wang H, Zhang Y, Li Z, Wu J, Sun Z, Wang W

Journal of Inflammation Research 2025, 18:13799-13821

Published Date: 6 October 2025

Clinical Features, Treatment Effectiveness and Long-Term Outcomes in Children with Moderate-to-Severe Generalized Pustular Psoriasis: A Retrospective Cohort Study

Cao Z, Peng B, Li Z, Li R, Fan R, Mi B, Li B, Song X, Shi J, Geng S

Journal of Inflammation Research 2025, 18:13787-13798

Published Date: 4 October 2025

Kimura Disease: Retrospective Analysis of 53 Cases and Three Mepolizumab-Responsive Cases

Zhu W, Zhang L, Zhang J, Wang W, Xiang Y, He D, Shi J, Liang Y, Shi Y, Ning X, Jin M, Ye L

Journal of Inflammation Research 2025, 18:13773-13785

Published Date: 4 October 2025

Prediction of Antibiotic Efficacy in Cerebral Hemorrhage-Associated Pneumonia Using Inflammatory Hematological Indices: A Retrospective Study

Wang X, Yang X, Yao Y, Hu H, Zhao Y, Zhu Z

Journal of Inflammation Research 2025, 18:13763-13772

Published Date: 4 October 2025

Mechanistic Exploration of Shenling Baizhu Powder in Treating Irinotecan-Associated Diarrhea: A Study Based on Network Pharmacology and Experimental Validation

Liu M, Xiong Y, Yuan J, Jin Q, Zhang JC, Shi RJ, Cheng ZQ

Journal of Inflammation Research 2025, 18:13745-13761

Published Date: 3 October 2025

Age-Stratified Immune-Inflammatory Profiles and Prognostic Implications of Old Patients in the ICU: A Prospective Study

Lian H, Wang G, Zhang Q, Zhao H, Wang X

Journal of Inflammation Research 2025, 18:13727-13743

Published Date: 3 October 2025

Comprehensive Analysis and Experimental Validation of Immune-Related Biomarkers and Immune Microenvironment in Diabetic Nephropathy

Zhou W, Zeng Z, Li X, Yang M

Journal of Inflammation Research 2025, 18:13711-13726

Published Date: 3 October 2025

Identification of Mitophagy-Related Genes and Analysis of Immune Infiltration in Atherosclerosis

Zhang J, Wang X, Chen X, Liu M

Journal of Inflammation Research 2025, 18:13689-13710

Published Date: 3 October 2025

Development of a Prediction Model for Combined Assessment of SII, Albumin, and Fibrinogen to Evaluate Frailty Risk in Patients with Inflammatory Bowel Disease

Li M, You J, Li X, Wang J

Journal of Inflammation Research 2025, 18:13677-13688

Published Date: 13 November 2025

Review

Dermatological Inflammation

The Role of Fibroblasts in Atopic Dermatitis: Establishing Proinflammatory Microenvironments and Mediating Cellular Crosstalk

Yao WH, Sun C, Su Z, Wang P, Zeng YP

Journal of Inflammation Research 2025, 18:13665-13676

Published Date: 11 November 2025

A Nomogram for Early Prediction of Infected Pancreatic Necrosis Based on Contrast-Enhanced CT Radiomics and Inflammatory Indicators

Yao Q, Duan Y, Jin C, Li X, Wei S, Shi Y, Zhang Y, Zhang J, Liu C

Journal of Inflammation Research 2025, 18:13651-13663

Published Date: 3 October 2025

Identification of Biomarkers for Sepsis-Induced Acute Lung Injury Through Bioinformatics and Machine Learning Approaches, with Experimental Validation

Luo Y, Xu J, He N, Cao W

Journal of Inflammation Research 2025, 18:13635-13650

Published Date: 4 October 2025

Isolated Central Nervous System FHL3 in an Asian Pediatric Patient: A Case Report and Literature Review

Zhang Z, Duan H, Zhang C, He F, Yin F, Yang L, Peng J

Journal of Inflammation Research 2025, 18:13625-13633

Published Date: 2 October 2025

Prognostic Value of SIRI in Sepsis: A Retrospective Study and Machine Learning-Based Model Development

Zhu Y, Wang Z, Li S, Xiao X, Liu Y, He J, Huang F, Wang J

Journal of Inflammation Research 2025, 18:13609-13623

Published Date: 1 October 2025

Low-Intensity Pulsed Ultrasound Promotes a Treg-Like Phenotype and Suppresses a Th17-Like Phenotype in CD4+ T Cells via YAP/TAZ Activation in vitro

Yang R, Zhang X, Zhang Y, Man Y, Yang X

Journal of Inflammation Research 2025, 18:13593-13608

Published Date: 2 October 2025

Sirp-α Antibody Inhibits Renal Cell Carcinoma Progression via Akt1/Akt2 Modulation in Tumor-Associated Macrophages

Hao J, Liu N, Huang X, Zhou H, Li H, Zhang Y, Yu B, Bi Z, Song X, Li S, Chen K, Li N, Zhu C, Wang J

Journal of Inflammation Research 2025, 18:13575-13592

Published Date: 1 October 2025

The Ubiquitin-Proteasome System: A Key Regulatory Hub in Myocarditis Leading to Dilated Cardiomyopathy

Yin X, Wang D, Lyu J, Ding J, Pan Z, Wang K, Guo X

Journal of Inflammation Research 2025, 18:13555-13574

Published Date: 1 October 2025

Mechanistic Insights into Qin Bi Yin for Psoriasis Treatment Using Network Pharmacology, Experimental Validation, and Molecular Docking

Zhang S, Du Y, Zhang H, Duan X, Li L

Journal of Inflammation Research 2025, 18:13535-13554

Published Date: 1 October 2025

Original Research

The EZH2 Inhibitor GSK126 Alleviates Thromboinflammation in Deep Vein Thrombosis by Suppressing TLR4 Signaling via H3K27me3 Modulation

Zhou R, Luo J, Zheng H

Journal of Inflammation Research 2025, 18:13519-13534

Published Date: 2 October 2025

Bromodomain and Extraterminal Protein Inhibition: A Novel Therapeutic Strategy in Arthritis

Sheng W, Zhao J, Yu F, Wang D, Zeng H, Liu P

Journal of Inflammation Research 2025, 18:13503-13517

Published Date: 30 September 2025

MRPL35 Attenuates Neonatal Parenteral Nutrition-Associated Cholestasis by Modulating the ROS/JNK/NF-κB Pathway

Sun X, Shen L, Zheng R, Tao M, Chen S

Journal of Inflammation Research 2025, 18:13489-13502

Published Date: 30 September 2025

The Role of Butyric Acid and Microorganisms in Chronic Inflammatory Diseases and Microbiome-Based Therapeutics

Liu Z, Jiang Y, Fan Q, Li S, Wang Y

Journal of Inflammation Research 2025, 18:13465-13487

Published Date: 29 September 2025

The Association Between Markers of Lipid Homeostasis, Inflammation, and Atherosclerosis Index in Patients with Type 2 Diabetes and Coronary Heart Disease Stratified by Glycemic Control: A Cross-Sectional Study

Yang P, Dai T, Liu B, Yin J, Li X, Zai W, Zhuang H

Journal of Inflammation Research 2025, 18:13453-13463

Published Date: 30 September 2025

Dual Effects of Sodium Houttuyfonate Against Acute Rhinosinusitis: Antibacterial Action and Epithelial Barrier Repair Through the p38 MAPK/ERK Pathway

Fang Y, Zhou H, Li W, Bai L, Sun X, He K, Xue S, Wu Y

Journal of Inflammation Research 2025, 18:13433-13452

Published Date: 29 September 2025

Purinergic Receptors in Dendritic Cells

Wang M, Zhao X, Hou S, Wu Z, Yin HY

Journal of Inflammation Research 2025, 18:13423-13432

Published Date: 30 September 2025

Decreasing Procalcitonin and Its Ratio to Albumin Predict Mortality in Patients with Abdominal Sepsis

Li Q, Lyu ZC, Zhang LL, Li YR, Chen JY, Yuan YW

Journal of Inflammation Research 2025, 18:13413-13422

Published Date: 26 September 2025

Original Research

Establishment and Validation of a Novel Nutritional-Immune-Inflammatory Score Model for Predicting Survival Prognosis in Hepatocellular Carcinoma Patients Treated with PD-1 Inhibitors

Liu K, Lv Y, Fu S, Mao Y, Xu Y, Huang S, Wu J

Journal of Inflammation Research 2025, 18:13397-13412

Published Date: 27 September 2025

Integrated Single-Cell Analysis Reveals the Heterogeneity of Tumor-Associated Macrophages and Their Implications for Immunotherapy in Colorectal Cancer

Xu G, Fang B, Tang X, Wei Q, Li J

Journal of Inflammation Research 2025, 18:13381-13396

Published Date: 26 September 2025

Proteomic Profiling of Serum-Derived Exosomes in Oral Lichen Planus: FN1-C3-ECM Crosstalk as a Potential Novel Therapeutic Target

Wang XY, Deng YF, Xue SJ, Guan WQ

Journal of Inflammation Research 2025, 18:13359-13379

Published Date: 26 September 2025

Relationship Between Lymphocyte-Associated Inflammatory Markers and Post-Stroke Cognitive Impairment

Hu QY, Liu J, Cui CH, Guo MF, Shi YT, Zhang XM, Jia BF, Li XY, Sun SJ

Journal of Inflammation Research 2025, 18:13347-13358

Published Date: 25 September 2025

Integrating Pre- and Postoperative Systemic Inflammatory Markers for Acute Kidney Injury Prediction Following Radical Cystectomy: A Multi-Center Retrospective Study

Liu Z, Fan P, Lu Y, Cao M, Yao W, Chen D, Ji F

Journal of Inflammation Research 2025, 18:13335-13345

Published Date: 25 September 2025

The Value of Combined Detection of Systemic Inflammation Response Index and Prognostic Nutritional Index in Predicting Short-Term Prognosis of Myasthenia Gravis

Chen T, Chen H, Wen Y, Huang Y, Lin Z, Liang Q, Huang W

Journal of Inflammation Research 2025, 18:13319-13333

Published Date: 26 September 2025

Prolonged Acute Kidney Injury and Symmetrical Peripheral Gangrene: A Rare Case Report of Acute Promyelocytic Leukemia

Kong YK, Shu H, Zhang WJ, Wu CY

Journal of Inflammation Research 2025, 18:13313-13318

Published Date: 25 September 2025

Review

Crosstalk Between Cell Death and the cGAS-STING Pathway in Sepsis-Associated Acute Lung Injury

Li X, Wang M, Li Y, Huang Y, Zhang X

Journal of Inflammation Research 2025, 18:13291-13312

Published Date: 26 September 2025

Histopathological Characteristics of Nasal Tissues From Paediatric Patients with Chronic Rhinosinusitis and Nasal Polyps Requiring Revision Surgery

Hsieh SF, Wu PW, Chiu CH, Huang YL, Huang CC

Journal of Inflammation Research 2025, 18:13279-13289

Published Date: 26 September 2025

A Focus on the Mechanisms of Alteration in Host Lymphocyte Level Following Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) Infection

Chen Y, Miller H, Benlagha K, Byazrova MG, Filatov AV, Zhang Z, Liu L, Ding Y, Yang L, Gong Q, Liu C

Journal of Inflammation Research 2025, 18:13265-13277

Published Date: 24 September 2025

Original Research

Association Between High-Sensitivity C-Reactive Protein and Longitudinal Changes in Arteriosclerosis Over Time: The Kailuan Prospective Cohort Study

Li W, Liang P, Han Z, Liu X, An S, Wang X, Gao Y, Chen S, Wu S

Journal of Inflammation Research 2025, 18:13255-13264

Published Date: 24 September 2025

Validate the Treatment of Crohn’s Disease with Chaihu Guizhi Decoction Through Network Pharmacology, Molecular Dynamics Simulation, and in vivo Experiments

Zhou W, Wu Y, Yang J, Saini YK, Fu R, Chen B, Cao G, Zhang J

Journal of Inflammation Research 2025, 18:13235-13254

Published Date: 24 September 2025

Identifying Chemokine System-Related Phenotype to Predict Immune Feature in Pan-Cancer and Prognostic Signature for Lung Adenocarcinoma

Zhao T, Wu X, Guo S, Nie J, Fang S, Wang L, Li X, Nie T, Yao K, Du X, Wang Y, Yuan Y, Ni J

Journal of Inflammation Research 2025, 18:13213-13234

Published Date: 22 September 2025

Review

Microbiome–Gut–Brain Axis: Implications for the Links Between Inflammatory Bowel Disease and Neuropsychiatric Disorders

Tian CM, Yang MF, Kong C, Luo D, Yue NN, Zhao HL, Zhang Y, Lu JP, Liang YJ, Song Y, Wei DR, Yao J, Wang LS, Li DF

Journal of Inflammation Research 2025, 18:13183-13212

Published Date: 23 September 2025

Diagnostic Value and Regulatory Mechanism of miR-322-5p in Coronary Heart Disease

Wang M, Wang J, Xie Y

Journal of Inflammation Research 2025, 18:13173-13182

Published Date: 20 September 2025

The m6A Modification in T Helper Cells Regulates the Pathogenesis of Autoimmune Diseases

Jiang Q, Wang X, Wu Y, Cui D

Journal of Inflammation Research 2025, 18:13159-13172

Published Date: 19 September 2025

Review

The Emerging Roles and Therapeutic Potential of Unconventional T Cells in Sepsis

Gu S, Zhang P, Zhang C, Tang T, Chang T, Dong L, Gao W, Tang Z

Journal of Inflammation Research 2025, 18:13139-13157

Published Date: 20 September 2025

Review

Tocilizumab for Non-Infectious Uveitis: A Systematic Review

Cao H, Bian K, Ma C, Zhang N, Ma X

Journal of Inflammation Research 2025, 18:13117-13138

Published Date: 20 September 2025

Influenza A (H1N1) and COVID-19 Pneumonias: An Evaluation in the Light of New Hematologic Indices

Yeşildağ M, Kocabas R

Journal of Inflammation Research 2025, 18:13103-13116

Published Date: 19 September 2025

Druggable Targets for Pelvic Inflammatory Disease: Mendelian Randomization and Experimental Validation

Dang C, Wu Q, Pan J, Yu X, Liu J, Liu P, Wang Y

Journal of Inflammation Research 2025, 18:13089-13101

Published Date: 19 September 2025

Machine Learning and Mendelian Randomization Identify Six Cell Death-Related Genes Driving Ulcerative Colitis Progression and Treatment Response

Dai L, Zhou W, Li A, Xu X, Yuan B, Zhang Z

Journal of Inflammation Research 2025, 18:13073-13088

Published Date: 19 September 2025

Endothelial Injury-Induced Shedding of Thrombomodulin as a Biomarker for Predicting Adverse Prognosis in Sepsis

Meng X, Chen X, Liu J, Yuan X, Guo D

Journal of Inflammation Research 2025, 18:13055-13072

Published Date: 20 September 2025

lncRNA RNA AC114812 Regulates the Inflammatory Response of Periodontal Ligament Cells via the miR-181a-5p-SPP1 Axis

Tong T, Zhao F, Tao R, Liu C, Liu B

Journal of Inflammation Research 2025, 18:13039-13053

Published Date: 19 September 2025

Programmed Cell Death in Diabetic Kidney Disease: Mechanisms and Therapeutic Targeting

Tang S, Sun Y, Sun W, Kang X, Zhao X, Jiang L, Gao Q, An X, Ji H, Lian F

Journal of Inflammation Research 2025, 18:13001-13037

Published Date: 19 September 2025

Elevated Serum Podoplanin Levels Correlate with Disease Severity and Inflammation in Ulcerative Colitis: A Cross-Sectional Study

Huang X, Tang C

Journal of Inflammation Research 2025, 18:12989-13000

Published Date: 18 September 2025

Clinical Value of Lymphocyte Count in Risk Prediction of Papillary Thyroid Carcinoma: A Case-Control Study in a Chinese Population

Qiu XP, Xie RY, Chen Y, Tu M, Wang T

Journal of Inflammation Research 2025, 18:12971-12988

Published Date: 19 September 2025

Downregulation of IL-20RA in Cerebrospinal Fluid Associated with the Risk of Moyamoya Disease: A Molecular Signatures Analysis with an Inflammation Proteomics Landscape

Xia C, Liu B, Hu Y, Cheng H, Ye L

Journal of Inflammation Research 2025, 18:12961-12970

Published Date: 18 September 2025

TNF/NF-κB Signaling Pathway is Involved in Mechanisms of Tongluo Decoction on Rat Models with Sequelae of Pelvic Inflammatory Disease

Liu B, Yang F, Pu X, Yu J, Wang Q

Journal of Inflammation Research 2025, 18:12949-12960

Published Date: 17 September 2025

Volatile Oil From Acorus Gramineus Rhizoma Synergizes with Crebanine to Alleviate Oxidative Stress and Endoplasmic Reticulum Stress in Myocardial Ischemia-Reperfusion Injury by Suppressing GRP78-PERK/ATF6-CHOP and MAPK-NF-κB-TNF-α Signaling Pathways

Zha L, Cui L, Mei J, Pu J, Hao J, Fan X, Wang H, Fang H, Ma Y

Journal of Inflammation Research 2025, 18:12929-12948

Published Date: 17 September 2025

Identification of Core SASP-Related Genes TGFBI and ANXA6 for Diagnosing Ulcerative Colitis-Related Colorectal Cancer Through Machine Learning

Zhang J, Wang P, Yuan S, Zhang Y

Journal of Inflammation Research 2025, 18:12909-12928

Published Date: 18 September 2025

Huiyang Shengji Unguent Promotes Lymphangiogenesis and Wound Healing in Diabetic Chronic Wounds: Combined Insights from Proteomics and in vivo and in vitro Analyses

Yu F, Lin L, Tang X, He X, Xu X

Journal of Inflammation Research 2025, 18:12883-12908

Published Date: 16 September 2025

The Associations of Neutrophil-to-Lymphocyte Ratio, Monocyte-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Systemic Immune-Inflammatory Index with the Severity and Prognosis of Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy

Han A, Xie Y, Sun W, Zhou X, Zhang S, Xie Y, Yang N, Xie N

Journal of Inflammation Research 2025, 18:12869-12882

Published Date: 16 September 2025

Predicting Postoperative Pneumonia in ESCC After Neoadjuvant Chemo-Immunotherapy: Combined Use of ARISCAT Score and Inflammatory Biomarkers

Ding J, Zhao J, Qin T, Liu C, Yang Y, Xu D, Chen Y, Xu Z

Journal of Inflammation Research 2025, 18:12855-12868

Published Date: 16 September 2025

Comparison of Stepwise Lung Recruitment with Conventional Technique on Lung Function During One-Lung Ventilation in Infants Undergoing Segmental Lung Resection

Qi JL, Wang Y, Lu HB, Zhou R, He QJ, Jia YP

Journal of Inflammation Research 2025, 18:12847-12854

Published Date: 16 September 2025

The Crucial Roles of Platelets as Immune Mediators in Sepsis

Yang X, Song J, Ma H, Hua N, Bai Y, Ju Y, Shen JW, Zheng W, Jiang S

Journal of Inflammation Research 2025, 18:12825-12845

Published Date: 16 September 2025

Severe Community-Acquired Pneumonia with Disseminated Infection Caused by Highly Virulent Pseudomonas aeruginosa: Successful Treatment of a Case

Teng P, Peng J, Zhang X, Wang Y, Jiang C, Wang S, Wang M, Han X, Liu X

Journal of Inflammation Research 2025, 18:12817-12824

Published Date: 17 September 2025

Fatty Acid Transporter CD36 Promotes Ox-LDL-Induced Senescence of Vascular Endothelial Cells in Preeclampsia

Xiao Y, Tao M, Yu Y, Bai R, Zhuang Y, Huang Q, He J, Lin Z, Gao M, Li J, Wang Y, Xu Y, Shen X, Huang Z, Yao Y, Chen Z, Chen Q, Wang Z

Journal of Inflammation Research 2025, 18:12801-12816

Published Date: 16 September 2025

Investigation of Antioxidant Enzymes (GST, GSH, R-GSSG) in Erythrocytes of COVID-19 Patients: A One-Month Observation

Cecerska-Heryć E, Serwin N, Pius-Sadowska E, Głowacka K, Polikowska A, Goszka M, Birger R, Budkowska M, Machaliński B, Dołęgowska B

Journal of Inflammation Research 2025, 18:12783-12800

Published Date: 16 September 2025

Study on the Effects of Tranexamic Acid on Perioperative Inflammation, Long-Term Functional Recovery, and Satisfaction in Total Knee Arthroplasty: A Follow-up Study

Lin S, Zhang X, Xia X, Xu G, Pan H

Journal of Inflammation Research 2025, 18:12769-12781

Published Date: 15 September 2025

Single-Cell RNA Sequencing Reveals Cellular Heterogeneity and Microenvironmental Remodeling in Human Ureteral Scar Stricture Tissue

Ding X, Li G, Yang Y, Song Z, Shen X, Hou B, Zhang M, Sang S, Dai J, Zhang J, Hao Z, Chen Y, Liang C

Journal of Inflammation Research 2025, 18:12749-12768

Published Date: 15 September 2025

The Predictive Value of ADC Values, Degree of Edema and the Systemic Immune-Inflammation Index for Early Postoperative Recurrence in High-Grade Gliomas

Wang M, Wang S, Li Q, Jiang X

Journal of Inflammation Research 2025, 18:12739-12748

Published Date: 15 September 2025

Association of Systemic Inflammatory Biomarkers (NLR, MLR, PLR, SII, SIRI) with Preeclampsia-Related Kidney Injury: A Retrospective Observational Study

Gao LN, Yan D, Liu XH, Chen D, Guo H, Liu J

Journal of Inflammation Research 2025, 18:12725-12738

Published Date: 15 September 2025

Correlation Between Immune-Inflammatory Biomarkers During Pregnancy and Postpartum and Adverse Outcomes of Preeclampsia: A Longitudinal Retrospective Analysis

Guo X, Tao W, Zhao Q, Qu C, Li X, Sun X, Xu Z

Journal of Inflammation Research 2025, 18:12713-12723

Published Date: 15 September 2025

Glasgow Prognostic Score Serves as a Prognostic Factor of Clinical Outcome in Patients with Newly Diagnosed Multiple Myeloma

Li S, Zhang L, Liu S, Liang Z, Wang W, Wang Y, Liang Y

Journal of Inflammation Research 2025, 18:12699-12711

Published Date: 13 September 2025

Swainsonine Protects Human Thyrocytes from Fas-Induced Apoptosis: In vitro Study on Nthy-Ori 3-1 Cell Line

Trzos S, Opydo M, Bochenek M, Link-Lenczowski P, Pocheć E

Journal of Inflammation Research 2025, 18:12677-12697

Published Date: 14 September 2025

The Bidirectional Role of Obesity and Aging in the Pathogenesis of Osteoarthritis: Molecular Mechanisms, Epigenetic Insights, and Therapeutic Implications

Lin C, Yang J, Su H, Zhang X, Wang B

Journal of Inflammation Research 2025, 18:12637-12676

Published Date: 12 September 2025

Wheat-Grain Moxibustion Ameliorates Ulcerative Colitis: Suppressing Intestinal Inflammation, Modulating Gut Microbiota, and Restoring Mucosal Barrier Integrity

Zhu T, Sun SY, Yang SX, Ji YF, Wan HY, Ji LX

Journal of Inflammation Research 2025, 18:12619-12636

Published Date: 12 September 2025

The Effects and Mechanisms of Patchouli Alcohol on Experimental Periodontitis Rats Based on the OPG/RANK/RANKL/P38 MAPK Signaling Pathway

Zhang S, Duan F, He T, Sun C, Zhen M, Liang E, Liu X, Dai Y, Zhan R, Hu N, Xia Y, Liu S

Journal of Inflammation Research 2025, 18:12599-12617

Published Date: 13 September 2025

Exploring Inflammatory-Related Factors Associated with Postoperative Length of Hospital Stay in Elderly Patients Undergoing Gastrointestinal Tumor Surgery Using Machine Learning

Liu J, Hu Y, Zhan X, Wang H, Li C

Journal of Inflammation Research 2025, 18:12589-12597

Published Date: 12 September 2025

Viral Triggers Exposed: A Systematic Review of Virus-Induced Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis

Fetriani U, Zakiawati D

Journal of Inflammation Research 2025, 18:12575-12588

Published Date: 12 September 2025

Review

Gut–Spinal Cord Axis in Spinal Cord Injury: Bidirectional Inflammatory Mechanisms and Microbiota-Targeted Therapeutic Strategies

Dong J, Xie T, Shi C, Feng G, Zhang H, Xu Z, Dong L

Journal of Inflammation Research 2025, 18:12549-12573

Published Date: 12 September 2025

Upadacitinib Attenuates Lipopolysaccharide- and Cecal Ligation and Puncture-Induced Inflammatory Responses by Inhibiting NF-κB and Its Downstream Cytokines

Yao Q, Yang X, Yan H, Wang Y, Ma Y, Xu N

Journal of Inflammation Research 2025, 18:12533-12548

Published Date: 10 September 2025

The Lipid-Oxidative Stress Axis: Novel Therapeutic Targets for Podocytopathy

Liu Y, Zou M, Wang Y

Journal of Inflammation Research 2025, 18:12505-12532

Published Date: 11 September 2025

Original Research

SCIN: A Key Driver in Chronic Atrophic Gastritis-Gastric Cancer Cascade with Implications for Immunity and Prognosis

Wu K, Ye Y, Pei B, Song B, Li T, Yang Q, Jin Y, Li X

Journal of Inflammation Research 2025, 18:12485-12503

Published Date: 10 September 2025

Urolithin-C Suppresses Inflammation by Blocking NF-κB Signaling Pathway in LPS-Induced RAW 264.7 Macrophages

Manjappa VK, Venkatappa MM, Urs D, Basavarajaiah SM, Venkataramaiah S, Mahendranathsingh SBS, Mohan S, Pushpavathi HR, Krishnappa DK, Sannaningaiah D

Journal of Inflammation Research 2025, 18:12463-12483

Published Date: 9 September 2025

Quercetin-Loaded Nanoparticles: A Promising Therapeutic Strategy for Inflammatory Bowel Disease

Wang W, Li M, Liu Y, Weigmann B

Journal of Inflammation Research 2025, 18:12447-12461

Published Date: 10 September 2025

Targeting Eosinophils in Asthmatic Inflammation: Benefits and Drawbacks

Broide D

Journal of Inflammation Research 2025, 18:12421-12445

Published Date: 9 September 2025

Angiotensin-(1-7) Inhibits Angiogenesis and Alleviates Joint Damage in CIA Mice via the Hippo–YAP Pathway

Zhang S, Sheng M, Yu D, Qian K, Zhang Y, Huang W, Ren F, Tang L

Journal of Inflammation Research 2025, 18:12401-12419

Published Date: 10 September 2025

Identification of Novel Biomarkers Associated with Corticosteroid Resistance in Asthma by Bioinformatics Analysis and Experimental Validation

Xuan L, Ren L, Zhang W, An Z

Journal of Inflammation Research 2025, 18:12379-12400

Published Date: 9 September 2025

SMP30 Attenuates Lens Epithelial Cells Pyroptosis of Cataract via the Downregulation of p-STAT3

Liang Y, Gan Q, Zhong X, Lan T, Yang Y, Lin L, Tang C, Liang H

Journal of Inflammation Research 2025, 18:12361-12377

Published Date: 8 September 2025

Programmed Cell Death of Chondrocytes, Synovial Cells, Osteoclasts, and Subchondral Bone Cells in Osteoarthritis

Huang J, Wu L, Zhao Y, Zhao H

Journal of Inflammation Research 2025, 18:12323-12360

Published Date: 8 September 2025

The Impact of the Trajectory of the Monocyte-to-High-Density Lipoprotein Cholesterol Ratio on the Incidence of Metabolic Dysfunction-Associated Fatty Liver Disease: Random Forest Anaylsis, Trajectory Anaylsis, and Mendelian Randomization Study

Zhang W, Ji S, Chen R, Chen N, Zhao X, Han D, Dong R, Hu Z

Journal of Inflammation Research 2025, 18:12311-12322

Published Date: 8 September 2025

Downregulation of IFIT3 Relieves the Inflammatory Response in Ulcerative Colitis via Selectively Regulating Macrophage M1 Polarization and the STAT1/2 Signaling Pathway

Du M, Tao Y, Yang K, Liu J, Yang X

Journal of Inflammation Research 2025, 18:12295-12309

Published Date: 6 September 2025

Regulatory Mechanism and Drug Therapy of NLRP3 Inflammasome in Recurrent Pregnancy Loss: Research Status and Prospect

Cui Y, Yang Y, Li Y, Zhang Y, Niu D, Feng X

Journal of Inflammation Research 2025, 18:12279-12294

Published Date: 6 September 2025

Development of Diagnostic and Predictive Models for COPD Based on Anoikis Resistance

Hu W, Sun J, Wang M, Wang Y, Mu C, Yu X, Yuan P, Han W, Li Y, Li Q

Journal of Inflammation Research 2025, 18:12263-12278

Published Date: 6 September 2025

Xianglian Anchang Decoction Mitigates Ulcerative Colitis via Inhibition of TLR-4-Mediated Pyroptosis

Zhang S, Wang Y, Ren X, Chen H, Gao T, Liu Y, Lu L, Ma J, Bai H, Wang Y

Journal of Inflammation Research 2025, 18:12245-12261

Published Date: 4 September 2025

The Role of Inflammatory Biomarkers (IL-1, IL-6, TNF-α, and Alpha-Amylase) in Saliva on Post-Odontectomy Swelling: A Rapid Review

Saim FI, Sjamsudin E, Najmi N

Journal of Inflammation Research 2025, 18:12227-12243

Published Date: 4 September 2025

SETD7 Dual Role in Disease and Opportunities for Therapeutic Intervention: Current Perspectives

Baboni F, Tembo KM, Zhou X, Li Q, Dai C, Zhao Y, Batoko S, Lan P, Chen Z

Journal of Inflammation Research 2025, 18:12191-12225

Published Date: 4 September 2025

Review

Therapeutic Potential of Acupuncture in Knee Osteoarthritis: Clinical Efficacy and Mechanistic Insights

Yao K, Shamim MF, Xia J, Liu TT, Guo Y, Lin X

Journal of Inflammation Research 2025, 18:12169-12190

Published Date: 5 September 2025

Exploring the Intervention Mechanism of Effective-Component Combination of Bufei Yishen Formula III for Airway Epithelial Barrier Injury: A miRNA-mRNA Regulatory Network Analysis

Liu C, Yue C, Xing X, Huang L, Wei Y, Zhao P, Li J, Guan Q

Journal of Inflammation Research 2025, 18:12145-12167

Published Date: 4 September 2025

Integrated Single-Cell and Transcriptome Analysis with Experimental Validation Reveals PANoptosis-Related Gene Signatures in the Immune Microenvironment of Autoimmune Thyroiditis

Zhao Z, Liu Z, Wang Q, Gao H, Song N, Yang X

Journal of Inflammation Research 2025, 18:12123-12143

Published Date: 3 September 2025

Combination of Polydatin and Hawthorn Leave Flavonoids Ameliorate Atherosclerotic Plaque Vulnerability in ApoE−/− Mice by Regulating Ferroptosis via the Nrf2/HO-1/GPX4 Axis

Chen J, Zhang X, Sun C, Wang Z, Li X, Hu L, Yuan Y, Wu M, Liu L

Journal of Inflammation Research 2025, 18:12105-12121

Published Date: 2 September 2025

CpG ODN Combined with Gold Nanorods Enhances Immune Activation and Its Potential Mechanism

Zhang S, Wang C, Jiang J, Li L, Luo J, Zhu J, Chen R

Journal of Inflammation Research 2025, 18:12089-12103

Published Date: 3 September 2025

Investigation into the Therapeutic Efficacy and Inflammatory Modulatory Effects of the Combined Use of 0.01% Atropine Eye Drops and Orthokeratology Lenses in the Management of Myopia Among Adolescent Patients

Wang H, Piao J, Yoo G, Li D, Liu J, In-chul J

Journal of Inflammation Research 2025, 18:12077-12087

Published Date: 2 September 2025

Identification of Potential Targets for EGFR-Regulated Nucleus Pulposus Degeneration Using Single-Cell RNA Sequencing and Machine Learning

Peng X, Wang Y, Chen Y, Hu Y, Wu F, Zhang L, Xu W, Wei Y

Journal of Inflammation Research 2025, 18:12059-12075

Published Date: 2 September 2025

IRF6 Enhances IFN-β Expression and Inhibits Viral Replication to Reduce the Severity of Herpetic Stromal Keratitis

Liu Z, Xia L

Journal of Inflammation Research 2025, 18:12045-12058

Published Date: 2 September 2025

The Pathophysiological Role of Mitochondrial Oxidative Stress in Rheumatic Diseases

Ma Z, Xu Q, Xu X

Journal of Inflammation Research 2025, 18:12021-12044

Published Date: 1 September 2025

The Dual Role of Myokines in Fatigue Associated with Inflammatory Joint Diseases

Chmielewski G, Kuna J, Jaśkiewicz Ł, Knapik M, Mikiewicz M, Majewski MS, Krajewska-Włodarczyk M

Journal of Inflammation Research 2025, 18:11999-12020

Published Date: 1 September 2025

Qijie Xiaopi Decoction Attenuates Gastric Mucosal Injury in PLGC Rats by Inducing Autophagy and Apoptosis Through PI3K/AKT/mTOR Pathway Inhibition

Shan Y, Ma Y, Chen H, Zhao S, Shi M, Bai M, Hu J

Journal of Inflammation Research 2025, 18:11979-11998

Published Date: 31 August 2025

Exploring the Correlation Between the Serum Homocysteine to Apolipoprotein A1 Ratio and the Severity of Coronary Artery Disease Based on Multicenter Data: A Novel Risk Assessment Parameter

Zhang J, Wu Z, Liu N, Liu L, Xu Q, Ma X, Huang Z, Li Z, Ding W, Chen S, Fang C

Journal of Inflammation Research 2025, 18:11963-11978

Published Date: 31 August 2025

Association Between Systemic Inflammation Response Index and Large Hemispheric Infarction: Development of a Predictive Diagnostic Model - A Retrospective Study

Jiao YX, Mu SZ, Kang B

Journal of Inflammation Research 2025, 18:11951-11962

Published Date: 30 August 2025

Electroacupuncture Regulates Oxidative Stress-Mediated NLRP3/ASC/Caspase-1 Pathway to Inhibit Microglial Activation: Alleviating Neuroinflammation and Depression in IBD

Li Z, Cao S, Yang J, Chen L, Jia L, Lu P, Liu J, Liu M, Liu Q

Journal of Inflammation Research 2025, 18:11935-11950

Published Date: 29 August 2025

Assessment of the Anti-Inflammatory Efficacy and Symptom Resolution Time of Kangfuxin Liquid Combined with Metronidazole in Recurrent Oral Ulcers

Shen L, Chen X, Zhang T

Journal of Inflammation Research 2025, 18:11925-11934

Published Date: 29 August 2025

Comprehensive Analysis of lncRNA/circRNAs-miRNA-mRNA Networks of Oral Lichen Planus

Zhang M, Miao L, Chen H, Sun H, Yang Q

Journal of Inflammation Research 2025, 18:11911-11924

Published Date: 29 August 2025

Exploration Progress on Inflammatory Responses and Immune Regulatory Mechanisms in Diabetic Retinopathy

Cheng S, Chen Z, Peng F, Deng P, Wang M, Liu S, Du Y, Zuo G

Journal of Inflammation Research 2025, 18:11895-11909

Published Date: 28 August 2025

A Retrospective Observational Analysis of Factors Determining the Formation of Pressure Ulcers in ICU Patients Treated for COVID-19

Woźniak A, Janc J, Leśnik P, Słabisz N, Uchmanowicz I

Journal of Inflammation Research 2025, 18:11883-11894

Published Date: 29 August 2025

Prognostic Enhancement in Gastric Cancer Through the Integration of Inflammatory Indices into the pTNM-Inflammation Staging System (pTNM-I)

Liu Z, Liu H, Zhang Y, Yang Y, Gao H

Journal of Inflammation Research 2025, 18:11869-11882

Published Date: 29 August 2025

PI3 as a Common Hub Gene Linking Atopic Dermatitis and Ulcerative Colitis Through Immune Cell Recruitment Mechanisms

Jian D, Chen J, Yuan J, Namrata K, Su D, Bai B

Journal of Inflammation Research 2025, 18:11853-11868

Published Date: 27 August 2025

Joint and Temporal Relationships of Systemic Inflammation and Atherogenic Dyslipidemia with Risk of Cardiometabolic Disease: A Longitudinal Cohort Study

Wang C, Zheng M, Yun C, Feng Z, Li Y, Chen S, Wu S, Xue H

Journal of Inflammation Research 2025, 18:11841-11852

Published Date: 27 August 2025

Macrophage Metabolic Reprogramming in Inflammatory Bowel Diseases: From Pathogenesis to Therapy

Zhang YF, Shi TT, Lin YL, Zhu YT, Lin S, Fang TY

Journal of Inflammation Research 2025, 18:11821-11839

Published Date: 27 August 2025

Original Research

CKS2 Mediates Hepatocellular Carcinoma Recurrence After Hepatic Ischemia-Reperfusion Injury Related to M2 Macrophages

Xia S, Qin X, Pan C, Fan D, Yang D

Journal of Inflammation Research 2025, 18:11801-11819

Published Date: 27 August 2025

Modified Neutrophil Platelet Scores (MNPs): A Novel Prognostic Marker in Colorectal Cancer

Tang Y, Zhao F, Zong B, Zhang H

Journal of Inflammation Research 2025, 18:11783-11799

Published Date: 27 August 2025

Review

The Role of Gut Microbiota in the Modulation of Pulmonary Immune Response to Viral Infection Through the Gut-Lung Axis

Chen N, Li L, Han Y, Chen Z

Journal of Inflammation Research 2025, 18:11755-11781

Published Date: 26 August 2025

Original Research

Network Pharmacology, Experimental Validation Explored Kakkalide to Ameliorate Endothelial Cell Dysfunction and Inflammatory Response

Li J, Yang S, Pan J, Qin Y, Ye H, Liao S, Shao Z, Rong G, Xia Z, Sun J, Shao Y

Journal of Inflammation Research 2025, 18:11737-11753

Published Date: 28 August 2025

Association of TIMP-2 Expression with Postoperative Prognosis in Hepatocellular Carcinoma Patients and Development of a Predictive Model

Liao SN, Li T, Liu ZH, Luo DC, Long XW, Liao XL, Liu JL

Journal of Inflammation Research 2025, 18:11703-11736

Published Date: 26 August 2025

Dysregulated Immune Responses in Sepsis: Insights From Treg-Related Gene Expression

Zhu G, Liao Y, Liu S, Liu P, Yang K, Tan M, Yi L, Zhang D, Xia H

Journal of Inflammation Research 2025, 18:11689-11702

Published Date: 27 August 2025

A Comprehensive Review of Food-Derived Compounds Targeting Pyroptosis for Colitis Therapy: From Effects to Mechanisms

Zhao JW, Li LY, Ye FW, Zhao WY

Journal of Inflammation Research 2025, 18:11667-11688

Published Date: 27 August 2025

From Brain to Lung: Emerging Insights into Mesenchymal Stem Cell-Derived Extracellular Vesicle-Associated Cargos in Ischemia-Reperfusion Injury

Zhang Y, Shi X, Li S, Yan S, Mei L, Zou Y, Yan C

Journal of Inflammation Research 2025, 18:11645-11666

Published Date: 25 August 2025

MiR-491-5p Targets B4GalT5 to Alleviate Airway Inflammation and Remodeling in Asthma by Regulating Pulmonary Oxidative Stress

Gao F, Zhu H, Lei J, Guo Y, Zhao L

Journal of Inflammation Research 2025, 18:11627-11644

Published Date: 25 August 2025

TM9SF1 as a Novel Prognostic Biomarker for Sepsis Severity and Mortality: A Longitudinal Study

Wang K, Zhang L, Zhou F, Zhao Z, Liu M, Huang M, Liu Y, Qiu G, Shen X, Xiao H, Cao F, Chen H, Xiao J

Journal of Inflammation Research 2025, 18:11611-11626

Published Date: 25 August 2025

Modified Naples Prognostic Score for Postoperative Prognostic Stratification in Patients with Oral Squamous Cell Carcinoma

Ran J, Liu Y, Yi X, Zhang F

Journal of Inflammation Research 2025, 18:11593-11610

Published Date: 24 August 2025

NRF2 Deficiency in Bladder Epithelial Cells Owing to Ubiquitination by N6-Methyladenosine-Modified TRIM21 Induces Oxidative Stress and Inflammation to Aggravate IC/BPS

Fan Z, Ge Q, Ni B, Zhang J, Du T, Xu H, Duan Z, Zhang S, Wang C, Xue J, Ling F, Chen Z, Shen B, Wei Z

Journal of Inflammation Research 2025, 18:11577-11592

Published Date: 24 August 2025

Exploring Salvia miltiorrhiza’s Therapeutic Effects on Adenomyosis by Inhibiting TNF-α/HIF-1α/IL-17-Driven Inflammatory Cascade: Mechanistic Insights from Target Prediction and Experimental Validation

Yang Q, Hong J, Zheng X, Liu X, Lin H, Chen L, Zhong F, Zhang Q, Jiang J, Sun P

Journal of Inflammation Research 2025, 18:11551-11575

Published Date: 22 August 2025

A Comprehensive Clinical Evaluation of Rilonacept in the Treatment of Recurrent Pericarditis: A Systematic Review

Yu Y, Chen J, Zhao Z, Qian M, Zhang Y, Ma C

Journal of Inflammation Research 2025, 18:11539-11549

Published Date: 22 August 2025

Anti-PS IgG Immune Complexes Impair Macrophage Phagocytosis in SLE via LOX-Dependent Oxidative Stress

Guan H, Huang L, Liu Y, Zhu E, Chen L, Li W, Wu H, Zhang X, Qin R, Zheng J, Mo Y, Zhong M, Xu B, Dai X, Wei Q, Chen Y, Wang Q, Zheng Z, Ma K, Tang C

Journal of Inflammation Research 2025, 18:11521-11538

Published Date: 22 August 2025

Association Between Neutrophil Percentage to-Albumin Ratio, Neutrophil to-Lymphocyte Ratio, Platelet-to Lymphocyte Ratio and in-Hospital Mortality in Elder Patients with Bloodstream Infections

Yu Z, Liu C, Gong M, Zhang P, Pei C, Liu X, Han X, Zhu P, Xu G, Du Y

Journal of Inflammation Research 2025, 18:11509-11520

Published Date: 22 August 2025

Time-Course Renal and Pulmonary Injury Analysis and Bioinformatics Screening of Core Pathogenic Genes and Immune Cell Infiltration Patterns in a Sepsis

Apizi A, Li J, Kamilijiang P, Yang CB, Wang ZK, Chai RF, Yu ZX

Journal of Inflammation Research 2025, 18:11493-11508

Published Date: 22 August 2025

Jianpi Lishi Jiedu Decoction (JLJD) Inhibit Th17 Cell Differentiation via the Jak/Stat3/RORγt Pathway in Colorectal Adenomas

Si M, Wang Y, Wu H, Huang Y, Ma M, Su K, Qiao D, Tao W, Liu W

Journal of Inflammation Research 2025, 18:11479-11492

Published Date: 21 August 2025

Age-Stratified Efficacy of Upadacitinib in Refractory Pediatric Crohn’s Disease and Geriatric Ulcerative Colitis: An Asian Cohort Study

Wu H, Lu Y, Su Y, Su T, Zhang M, Zhi M, Yao J

Journal of Inflammation Research 2025, 18:11463-11477

Published Date: 21 August 2025

Berberine Inhibits Acne-Related Lipid Secretion and Inflammation by Regulating the hsa-miR-3150a-3p/TP53 Pathway

Li T, Yang X, Wang X, Xu S

Journal of Inflammation Research 2025, 18:11451-11461

Published Date: 21 August 2025

Pharmacological Insights and Therapeutic Applications of Leonurus in Neurological Disorders

Wang Y, Wu X, Wu R, Sun X, Kang Y, Yu Y

Journal of Inflammation Research 2025, 18:11437-11450

Published Date: 21 August 2025

Identification and Experimental Validation of Oxidative Stress-Related Biomarkers in Ulcerative Colitis Using Machine Learning

Duan S, Yi Q, Qiu M, Zhu Z, Zhang Z, Gao Y, Zhang D

Journal of Inflammation Research 2025, 18:11415-11435

Published Date: 20 August 2025

Nsun2 Knockdown Alleviates Asthma Progression by Inhibiting Hnrnpk Expression Through Decreased 5-Methylcytosine

Wu F, Zhao J

Journal of Inflammation Research 2025, 18:11401-11413

Published Date: 21 August 2025

Reduced Platelet Aggregation and Plasma Cytokine Levels Mitigate Progressive Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Harm T, Rohlfing AK, Henes JK, Manzat N, Droppa M, Bongers MN, Heikenwaelder M, Müller KAL, Gawaz MP, Rath D

Journal of Inflammation Research 2025, 18:11385-11400

Published Date: 20 August 2025

Positive Association Between the Ratio of Neutrophil to High-Density Lipoprotein Cholesterol and Diabetes Incidence: A Retrospective Cohort Study

Chen Z, Li Y, Zhu X

Journal of Inflammation Research 2025, 18:11373-11384

Published Date: 20 August 2025

Identification of Neutrophil Extracellular Trap-Related Biomarkers in Diabetic Foot Ulcers Based on Bioinformatics

Liu K, Lei L, Yang XL, Zhang XH

Journal of Inflammation Research 2025, 18:11355-11372

Published Date: 18 August 2025

Machine Learning-Based Identification and Experimental Validation of Hub Ferroptosis-Related Cuproptosis Genes in Lupus Nephritis

Zhang S, Hu W, Zhang Y, Huang C, He Z, Xu J, Lin S, Yang B, Chen X

Journal of Inflammation Research 2025, 18:11335-11353

Published Date: 18 August 2025

Blockade of the Notch Pathway by Inhibition of Fucosylation Ameliorates Chondrocyte Inflammation and Extracellular Matrix Degradation

Zhang Y, Liu M, Wang X, Li N, Chang X, Xu J, Tian F, Wen X, Liu C, Li Y

Journal of Inflammation Research 2025, 18:11317-11334

Published Date: 18 August 2025

Comprehensive Analysis of Selenium Metabolism and Selenoproteins-Associated Gene Signatures in Ulcerative Colitis

Gao C, Wang J, Dai S, Wang D, Wang J

Journal of Inflammation Research 2025, 18:11299-11316

Published Date: 18 August 2025

Association Between Triglyceride-Glucose Index and Malignant Risk in Thyroid Nodules: A Cross-Sectional Analysis

Qiu X, Chen Y, Lin R, Zhang Z

Journal of Inflammation Research 2025, 18:11285-11297

Published Date: 19 August 2025

Original Research

Low-Frequency (1 Hz) Repetitive Trans-Spinal Magnetic Stimulation Attenuates NLRP3-Driven Neuroinflammation and Enhances Motor Recovery in Spinal Cord-Injured Mice

Song H, Yang Y, Huang L, Li Y, Sun B, Yu Z, Zhang M, Yang D

Journal of Inflammation Research 2025, 18:11263-11284

Published Date: 18 August 2025

Investigating the Underlying Mechanisms of Ma-Xing-Shi-Gan-Tang on Asthma via Metabolomics and Network Pharmacology

Yu Y, Wu S, Sun T, Zhou Z, Xu L, Peng D, Fu X

Journal of Inflammation Research 2025, 18:11245-11262

Published Date: 18 August 2025

Apoptosis-Related Non-Coding RNAs in Cardiac Fibrosis and Heart Failure: Implications for Pathogenesis and Therapy

Wu H, Xia L, Liu C

Journal of Inflammation Research 2025, 18:11217-11244

Published Date: 18 August 2025

Multi-Omics Profiling of the 42-Day Infant Gut as a Pilot Predictor of Atopic Dermatitis at One Year: A Birth Cohort Study in China

Zhao M, Li X, Li Y, Ma L, Liu Y, Wang S, Tian J, Liang Y, Shen C, Ma X, Yu D, Ma L

Journal of Inflammation Research 2025, 18:11205-11216

Published Date: 19 August 2025

Pathophysiological Insights Into the Role of Osteoclasts in Osteoarthritis: Mechanisms, Therapeutic Targets, and Future Directions

Chen S, Long Y, Guo Z, Di J, Xu J, Xiang C

Journal of Inflammation Research 2025, 18:11191-11204

Published Date: 17 August 2025

Perspectives

Through a Translational Lens: How Does Inflammation Contribute to the Pathogenesis of Asthma and Allergy?

Koziol-White CJ, Panettieri Jr RA

Journal of Inflammation Research 2025, 18:11189-11190

Published Date: 15 August 2025

Systemic Immune-Inflammatory Index and Systemic Inflammatory Response Index in the Assessment of Multiple Organ Dysfunction Syndrome Caused by Wasp Stings

Zhang X, Liang P, Tong C, Tao W, Zhang L, Zhao J, Fang Z, Zhao Z

Journal of Inflammation Research 2025, 18:11177-11187

Published Date: 15 August 2025

Transcriptome Combined with Mendelian Randomization to Identify and Validate Biomarkers Associated with Parthanatos in Sepsis

Zhao H, Li B, Jing X, Fan J, Zhao X, Li J, Wu S, Liang J, Zhang S

Journal of Inflammation Research 2025, 18:11155-11176

Published Date: 15 August 2025

Immune Signatures Distinguish Pure and Mixed Sepsis in Critical COVID-19: A Retrospective Cohort Study

Xiong L, Tang H, Xie Q, Fang H, Jing D, Chen L

Journal of Inflammation Research 2025, 18:11139-11153

Published Date: 14 August 2025

Effectiveness of Combining Thoracic Paravertebral Nerve Block and Serratus Anterior Plane Block in Non-Intubated Spontaneous-Ventilation Video-Assisted Thoracoscopic Surgery: A Retrospective Case-Control Study

Shi Z, Shao G, Zhang X, Shi Y, Rong G, Xu D, Zhu H, Yin D

Journal of Inflammation Research 2025, 18:11125-11137

Published Date: 14 August 2025

Rhoifolin Attenuates DSS-Induced Colitis in Mice by Modulating Gut Microbiota and Restoring Th17/Treg Balance

Xu H, Wang ZH, Zhong SL, Chen T, Liu SZ, Zhang SL, Xie XX, Liu T, Yang W

Journal of Inflammation Research 2025, 18:11109-11124

Published Date: 15 August 2025

ALDH2 Ameliorates Acute Gouty Arthritis Through Inhibiting NLRP3 Inflammasome and Pyroptosis by Nrf2/ROS Pathway

Tong S, Li X, Wang F, Cheng Q, Zhang P, Chen M, Xie Y, Lu X, Wu H

Journal of Inflammation Research 2025, 18:11095-11108

Published Date: 14 August 2025

Risk Prediction of Severe Complications Caused by Hymenoptera Insect Stings: Development and Validation of a Nomogram Mode

Guan J, Zhao Z, Wang Z, Huang M, Wang J, Liu Z, Ren Y, Lu Z, Hu S, Duan X

Journal of Inflammation Research 2025, 18:11083-11093

Published Date: 14 August 2025

Fecal Calprotectin Combined with Blood Inflammatory Biomarkers Enhances Diagnostic Evaluation and Supports Mucosal Healing Assessment in Pediatric Crohn’s Disease

Li P, Xu Y, Zhou Y, Sun R, Gu Z, Meng J

Journal of Inflammation Research 2025, 18:11073-11081

Published Date: 14 August 2025

Single-Cell RNA Sequencing Reveals Pericytes Acquire a Fibrotic Phenotype and Promote Mesenteric Adipose Tissue Fibrosis in Crohn’s Disease

Zhang D, Yu A, He M, Zhou Q, Sun S, Bai L, Xie F

Journal of Inflammation Research 2025, 18:11055-11071

Published Date: 14 August 2025

Bone Marrow Mesenchymal Stem Cells Can Prevent Pancreatic Fibrosis in Mice with Chronic Pancreatitis by Inhibiting the Activation of Pancreatic Stellate Cells

Jin T, Cheng H, Li M, Wei X, Wang X, Li X, Sun G, Zhang D, Hao J, Liu X

Journal of Inflammation Research 2025, 18:11041-11053

Published Date: 14 August 2025

Exploring the Role of Peroxisome-Related Processes and Key Marker Genes in Sepsis: Insights Into Immune Dynamics and Therapeutic Potential

Ye R, Du J, Luo Y

Journal of Inflammation Research 2025, 18:11029-11040

Published Date: 14 August 2025

Prognostic Nutritional Index is A Useful Predictive Marker for Morbidity and Mortality in Surgery for Perforated Peptic Ulcer

Jia G, Li K

Journal of Inflammation Research 2025, 18:11021-11028

Published Date: 14 August 2025

Oligoclonal Bands as Predictors of Disease Severity and Prognosis in Anti-NMDAR Encephalitis

Chen H, Chen T, Zhang S, Huang Y, Que X, Liang Q, Huang W

Journal of Inflammation Research 2025, 18:11009-11020

Published Date: 13 August 2025

Digital PCR-Based Assessment of Piwi-RNA PIR35982 as a Supporting Biomarker in Rheumatoid Arthritis

Cieśla M, Darmochwał-Kolarz D, Kubis H, Kolarz B

Journal of Inflammation Research 2025, 18:10995-11007

Published Date: 13 August 2025

Mechanism of Lipi Jiangzhuo Decoction in Improving Metabolic Dysfunction-Associated Steatohepatitis Through the PERK/PINK1/GPx4 Pathway

Pan L, Liu J, Pang G, Liu G, Tian Y

Journal of Inflammation Research 2025, 18:10969-10994

Published Date: 13 August 2025

Role of Interleukin-6 in Rheumatoid Arthritis-Associated Interstitial Lung Disease: Focus on the JAK/STAT Pathway and Macrophage Polarization

Yu Z, Liu J, Chen L, Xie J

Journal of Inflammation Research 2025, 18:10953-10967

Published Date: 13 August 2025

Downregulated RSAD2 Attenuates the Apoptosis of LPS-Stimulated RAW264.7 via NF-κB Signaling Pathway

Qi Z, Lu K, Huang M, Wang H, Liao R, Tang R

Journal of Inflammation Research 2025, 18:10939-10952

Published Date: 12 August 2025

Mechanistic Perspectives on Radiation-Induced Skin Injury and the Protective Effects of Berberine

Huang B, Chen G, Yan T, Ou X, Yang L, He T, Geng F, Zhou Z, Lyu G, Zhang S, Yu D

Journal of Inflammation Research 2025, 18:10919-10937

Published Date: 12 August 2025

Bioinformatics Analysis and Identification of Ferroptosis-Related Gene TIMP1 as a Potential Biomarker of Asthma

Guo Y, Zhu H, Lei J, Gao F, Ma J, Zhao L

Journal of Inflammation Research 2025, 18:10905-10917

Published Date: 12 August 2025

Unveiling the Therapeutic Potential of Jiawei Jianpi Huoyu Formula in Ulcerative Colitis: A Multi-Strategies and Experimental Study Integrating Network Pharmacology, Machine Learning, and Mendelian Randomization

Lu X, Sun Y, Gong M, Sun Z, Fan X, Huang N, Dai L, Xu E

Journal of Inflammation Research 2025, 18:10885-10903

Published Date: 12 August 2025

A Machine Learning Model Integrating Preoperative Blood-Based Indices for Early and Noninvasive Detection of Endometrial Cancer

Wang J, Wu H, Wang F, Wang Y, Gu J

Journal of Inflammation Research 2025, 18:10873-10884

Published Date: 12 August 2025

Comprehensive Analysis of Ferroptosis Markers in Lupus Nephritis Based on Bioinformatics Analysis and Experimental Validation

Zhang S, Hu W, Huang C, Lin X, Chen X

Journal of Inflammation Research 2025, 18:10855-10871

Published Date: 12 August 2025

Mediating Role of Lipid Accumulation Products (LAP) in the Association of WBC with MASLD: SWH 2021-2023

Zhou J, Cheng Z, Sun L, Chen Z

Journal of Inflammation Research 2025, 18:10845-10854

Published Date: 11 August 2025

Neutrophil-to-Albumin Ratio Predicts Stroke-Associated Pneumonia in Patients with Intracerebral Hemorrhage

Wan J, Liu Y, Yuan X, Fan S, Xiao Y, Fang F, Zhang Y

Journal of Inflammation Research 2025, 18:10835-10843

Published Date: 11 August 2025

Recent Advances in Host Immune Mechanisms Against Listeria monocytogenes Infection

Shang L, Xiang W, Lun M, Qu S, Yin Y, Xu Y, Zhou Y, Zhu P, Song Y

Journal of Inflammation Research 2025, 18:10821-10833

Published Date: 11 August 2025

The Partial Mediating Role of Arterial Stiffness in the Association Between Systemic Inflammation and Declining Renal Function in Type 2 Diabetes Mellitus: A Cross-Sectional Study

Guo Y, Zhao L, Zhu L, Wang L, Dong X

Journal of Inflammation Research 2025, 18:10807-10819

Published Date: 11 August 2025

Role of ILC2s as Potential Effector Cells of IL25-Mediated Type 2 Inflammation in Chronic Rhinosinusitis with Nasal Polyps in China

Yu Q, Song R, Ba Y, Geng J, Liu X, Liang T, Wang S, Zhao Y

Journal of Inflammation Research 2025, 18:10795-10805

Published Date: 10 August 2025

Advances in cGAS-STING Signaling in Fibrosis Diseases: Therapeutic Target in Pathological Scars

Zhao W, Angspatt A, Kitkumthorn N, Meevassana J

Journal of Inflammation Research 2025, 18:10777-10793

Published Date: 9 August 2025

A Chimeric Peptide Derived from a Bacterial Effector Protein Attenuates TLR-2/4-Mediated Production of Pro-Inflammatory Cytokines and Enhances the Cellular Availability of Gentamicin

Nandi BR, Patra B, Radhakrishnan GK

Journal of Inflammation Research 2025, 18:10751-10775

Published Date: 9 August 2025

Mechanisms of Cancer Cell Lymphatic Endothelialization in Tumor Lymphangiogenesis and Metastasis: A Comprehensive Review

Wang J, Hu Z, Qian X, Xin W, Cai W, Tang J

Journal of Inflammation Research 2025, 18:10741-10750

Published Date: 9 August 2025

Host Circulating Immunometabolism-Associated Biomarkers for Early Diagnosis of Active Tuberculosis: Multi-Omics Screening with Experimental Validation

Yang Z, Dong Y, Shang Y, Li H, Ren W, Li S, Pang Y

Journal of Inflammation Research 2025, 18:10723-10740

Published Date: 9 August 2025

Multi-Omics Analysis Identifies Immune Regulatory Networks in Sepsis-Associated Liver Injury: Experimental Validation and Clinical Relevance

Hong Y, Chen Q, Xie H, Ma M, Gan S, Zhang Y, Xu Z

Journal of Inflammation Research 2025, 18:10711-10722

Published Date: 9 August 2025

Knockdown of Long Noncoding RNA IPCRL1 Mitigates Myocardial Ischemia/Reperfusion Injury via miR-185-3p/JIP3 Axis and JNK Pathway

Chen J, Zhang Y, Zhang Z, Yu Z, Zhang H, Zhao Q

Journal of Inflammation Research 2025, 18:10695-10709

Published Date: 8 August 2025

Development and Validation of a CTE-Based Radiomics Nomogram for Predicting Clinical Adverse Outcomes in Patients with Stricturing Crohn’s Disease

Zhang B, Gao Y, Tong L, Hu J, Wu X

Journal of Inflammation Research 2025, 18:10681-10694

Published Date: 8 August 2025

IL-4 and IL-13 in Cardiovascular Disease: From Immune Modulation to Therapeutic Possibilities – A Narrative Review

Kılıç AT, Bora R, Toprak B

Journal of Inflammation Research 2025, 18:10669-10679

Published Date: 8 August 2025

Plasma Exosomal miR-17-5p Regulates Macrophage Polarization by Targeting Bcl11b in Sepsis-Induced Lung Injury

Xian Y, Sun Y, Wang L, Lin L, Wu Z, Zhang K, Chen R

Journal of Inflammation Research 2025, 18:10651-10668

Published Date: 8 August 2025

HALP Score as a Prognostic Biomarker in Tricuspid Valve Surgery: Association with in-Hospital and Long-Term Mortality

Demir Y, Yamak BA, Sevinç S, Karakurt H, Tükenmez Karakurt S, Kadiroğulları E, Aydın S, Kızıltunç E, Babur Güler G, Candemir M

Journal of Inflammation Research 2025, 18:10637-10649

Published Date: 8 August 2025

Medical Hemorrhoid Gel Ameliorates Croton Oil-Induced Hemorrhoids by Suppressing the NLRP3 Inflammasome Activation via NF-κB Signaling Pathway

Ai Z, Yuan D, Li Y, Cai J, Zhou D, Liu W

Journal of Inflammation Research 2025, 18:10619-10636

Published Date: 7 August 2025

Blood Cell Count-Based Inflammatory Markers Exhibit Superior Association with Diabetic Peripheral Neuropathy Compared to Protein-Based Markers

Ko FS, Wu TH, Su GY, Lin YH, Juan CC, Hwu CM

Journal of Inflammation Research 2025, 18:10609-10617

Published Date: 7 August 2025

Unveiling the Temporal Dynamics and Molecular Regulation Profiles of Neutrophil Extracellular Traps Following Spinal Cord Injury

Li J, Chang C, Li Y, Cui S, Bai J, Zhang C, Wang X, Li K, Jian F

Journal of Inflammation Research 2025, 18:10585-10608

Published Date: 6 August 2025

Refractory Gout and Metabolic Syndrome in a Chinese Cohort: A Propensity Score Matching and Nonlinear Relationship Analysis

Li J, Zhang J, Lu H, Li S, Zhang L, Tan N, Shang S, Li R, Ka Y, Wang S, Liu W

Journal of Inflammation Research 2025, 18:10573-10584

Published Date: 7 August 2025

Nomogram Incorporating Inflammatory Index, Pathology, and Molecular Classification for Predicting Recurrence in Patients with Stage I-III Endometrial Cancer: A Multi-Institutional Study

Xiao Y, Zheng Y, Tu Y, Tian C, Yu J, Lin H, Wen T, Jiang P, Wang Y

Journal of Inflammation Research 2025, 18:10559-10572

Published Date: 6 August 2025

Routine Laboratory Markers-Based Machine Learning Model for Predicting Severe Kawasaki Disease in Pediatric Patients

Wu M, Chen J, Gao Y, Chen H, Li W

Journal of Inflammation Research 2025, 18:10545-10558

Published Date: 4 August 2025

Original Research

Aggregation of Stress Granules Induced by Hypoxia and Lipopolysaccharide via PKR-p-eIF2α Pathway and 4EBP1 Pathway Inhibits the Inflammatory Response in Peri-Implantitis

Li S, Ma C, Fan C, Liu Y, Li J, Yin B, Zhong L, Bai N, Li Z

Journal of Inflammation Research 2025, 18:10533-10544

Published Date: 4 August 2025

Thyroid Hormone Pathways in Respiratory Diseases: Mechanism and Therapeutic Potential

Małujło-Balcerska E, Gałecka M, Pietras T

Journal of Inflammation Research 2025, 18:10519-10531

Published Date: 4 August 2025

Yuyang Decoction Regulates Macrophage Polarization and Repairs the Intestinal Mucosal Barrier via the TLRs/Tollip Signaling Pathway

Lian J, Jin G, Li J, Zhang W, Chang Y, Li W, Zhi H, Tian J, Liang C, Su J

Journal of Inflammation Research 2025, 18:10499-10518

Published Date: 4 August 2025

Glymphatic System Dysfunction in Thyroid Eye Disease Associated with Disease Activity and Duration

Zhang H, Jiang M, Liu Y, Lee XN, Fang Z, Li J, Li Y, Sun J, Tao X, Song X, Zhou H, Fan X

Journal of Inflammation Research 2025, 18:10489-10498

Published Date: 4 August 2025

Effect of Sodium Butyrate and Sishen Pill Combination on Diarrhea with Kidney-Yang Deficiency Syndrome Was Associated with Intestinal Mucosal Microbiota and Immune Barrier

Di J, Guo M, Peng M, Fang L, Shen J, Xiao N, Tan Z

Journal of Inflammation Research 2025, 18:10467-10487

Published Date: 4 August 2025

Original Research

In vitro Study of Fungus-Like Organisms Peronospora ficariae and Wilsoniana bliti as Potential Inhalant Allergens

Sztandera-Tymoczek M, Wdowiak-Wróbel S, Świderska U, Palusińska-Szysz M, Szuster-Ciesielska A

Journal of Inflammation Research 2025, 18:10445-10466

Published Date: 4 August 2025

Qingwen Hufei Granules Attenuate Lipopolysaccharide-Induced Acute Lung Injury by Suppressing NLRP3 Inflammasome-Dependent Pyroptosis

Long K, Yang Y, Wang Y, Wang B, Zhou H, Liu Y, Li Y, Yang S, Cao L, Huang T, Liu Y, Zhang H

Journal of Inflammation Research 2025, 18:10425-10443

Published Date: 4 August 2025

Chinese Massage (Tuina) Attenuates Knee Osteoarthritis by Modulating Autophagy-Related Cytokines: A Multidisciplinary Methodological Investigation

Wang Z, Zhao C, Li M, Zhang L, Diao J, Wu Y, Yang T, Shi M, Lei Y, Wang Y, Li M, Bian Y, Zhou Y, Xu H

Journal of Inflammation Research 2025, 18:10403-10423

Published Date: 2 August 2025

Long Non-Coding RNA lncTAF15:1-1 Promotes CCL5 Secretion and Cell Migration of Monocyte-Derived Dendritic Cells via PI3K/AKT/mTOR Pathway in Systemic Lupus Erythematosus

Xiang M, Sun Z, Ge Y, Zhang Z, Zheng C, Gao Z, Wang J, Xu J, Liang J, Wang Y

Journal of Inflammation Research 2025, 18:10389-10402

Published Date: 3 August 2025

Original Research

A Prospective Study on the Association of Mediterranean Diet Adherence and Physical Activity with Inflammatory Bowel Disease in Children

Lin Y, Li J, Shi Q, Zhang K, Yang J

Journal of Inflammation Research 2025, 18:10375-10387

Published Date: 2 August 2025

Focus on Cell Apoptosis, Pyroptosis and Ferroptosis to Explore Strategic Breakthrough for GDM

Li J, Fan L, Nan Y, Wang M, Yang S

Journal of Inflammation Research 2025, 18:10355-10373

Published Date: 2 August 2025

VOPP1 as a Novel Susceptibility Gene in Rheumatoid Arthritis: Insights Into Its Mechanisms From Mendelian Randomization and Experimental Validation

Wu W, Cai H, Nan Y, Tang J, Wang Y

Journal of Inflammation Research 2025, 18:10341-10354

Published Date: 2 August 2025

From Gut to Lung: The Role of Bile Acids in Rheumatoid Arthritis-Associated Interstitial Lung Disease (RA-ILD)

Shi YJ, Lin S, Shi YC, Xie J

Journal of Inflammation Research 2025, 18:10331-10340

Published Date: 2 August 2025

M-CSF Protects Against Ulcerative Colitis via Aconitate: Mendelian Randomization and Experimental Evidence

Zhang Y, Huang L, Yue N, Mai Z, Kong C, Tian C, Wei DR, Yao J, Wang L, Li D

Journal of Inflammation Research 2025, 18:10313-10329

Published Date: 31 July 2025

Systemic Immune-Inflammation Index and Systemic Inflammation Response Index Predict the Response to Radioiodine Therapy for Differentiated Thyroid Cancer [Corrigendum]

Wang Y, Chang J, Hu B, Yang S

Journal of Inflammation Research 2025, 18:10311-10312

Published Date: 31 July 2025

Association of Recreational Physical Activity with Gut Microbiota Diversity and Composition, and Symptom Burden in Crohn’s Disease: A Cross-Sectional Study

Sun S, Chen Y, Zheng M, Zhou M, Weng C, Fan Y, Lv B

Journal of Inflammation Research 2025, 18:10295-10310

Published Date: 31 July 2025

The Different Immune Response Between Onset and Remission of AQP4 Antibody-Positive Optic Neuritis Based on RNA Sequencing of Whole Blood

Shi R, Luo Y, Chen Y, Chen X, Li S, Chen Z, Wang K, Zou W

Journal of Inflammation Research 2025, 18:10283-10293

Published Date: 30 July 2025

The Persistent Threat of Chronic Inflammation on the Mortality Among Cervical Cancer Survivors: A Mendelian Randomization and Machine Learning Analysis Using UK Biobank and Chinese Cohort Data

Wang J, Chen Z, Guan M, Ma Z, Peng L, Chen J, Fiori PL, Carru C, Capobianco G, Coradduzza D, Zhou L

Journal of Inflammation Research 2025, 18:10267-10282

Published Date: 30 July 2025

Machine Learning Strategies for Preoperative PJI Diagnosis: Integrative Analysis of Serum and Synovial Fluid Markers

Chen B, Yang Y, Zhou H, Li F, Shen Y, Cheng Q, Huang W, Qin L

Journal of Inflammation Research 2025, 18:10253-10265

Published Date: 31 July 2025

Role and Therapeutic Potential of miR-301b-3p in Regulating the PI3K-AKT Pathway via PIK3CB in Eosinophilic Chronic Rhinosinusitis

Shu F, Wang Y, Jiang Y, Li L, Mu Z, Shi L, Gong X, Zhang B, Zhang F, Mao D

Journal of Inflammation Research 2025, 18:10235-10251

Published Date: 30 July 2025

Combined Analysis of Transcriptome and Mendelian Randomization Reveals AKT1 and PPARG as Biomarkers Related to Glucose Metabolism in Sepsis

Ma J, Li W, Ma Q, Ding L, Wang Z, Wang R, Huang Y, Ma G, Gao J

Journal of Inflammation Research 2025, 18:10213-10234

Published Date: 30 July 2025

Exploring the Potential of Coix Seeds to Mitigate High Humidity-Induced Gut Inflammation via Microbiota and Metabolite Modulation

Zhao P, Xiao C, Xuan M, Yan S, Yu X, Li W, Han L, Wang H, Zhao J, Zhang S, Zhong X

Journal of Inflammation Research 2025, 18:10193-10211

Published Date: 30 July 2025

The Clinical Value of Systemic Immune Inflammatory Index in Predicting the Prognosis of Patients with Bloodstream Infection

Ou S, Lu H, Qu R, Cui X, Xiong Z, Fan F, Yu X, Hasi C

Journal of Inflammation Research 2025, 18:10181-10192

Published Date: 30 July 2025

Review

The Role of Uridine in Health and Disease

Song C, Liu ZJ, Xu B, Zou R, Hu W

Journal of Inflammation Research 2025, 18:10163-10179

Published Date: 29 July 2025

Total Glucosides of Paeony (TGP) Inhibits Macrophages Infiltration and NLRP3-Mediated Inflammatory Response in Acute Gouty Arthritis Mice

Liu J, Liu G, Chu T, Wu Y, Yan X, Pang L, Fang W

Journal of Inflammation Research 2025, 18:10147-10161

Published Date: 29 July 2025

Interleukin Family-Based Signature Relates to Cancer-Associated Fibroblasts Spatial Distribution and Immune Therapy Response in Pancreatic Carcinoma

Cheng Y, Xiao S, Li X, Wang B, Lei Y, Sun P, Ma L, Zhu Y

Journal of Inflammation Research 2025, 18:10129-10146

Published Date: 29 July 2025

Increased CD163+ Macrophage Activation and High Expression of CD163 Promote Granulosa Cell Apoptosis in Polycystic Ovary Syndrome

Ye J, Wang S, Wang Z, Jiang Y, Jia J, Yang Y, Huo L, Liu X, Zhou Y, Yang Z, Mao J, Ma Y, Wang X

Journal of Inflammation Research 2025, 18:10111-10127

Published Date: 29 July 2025

Prognostic Value of Peripheral Blood nCD64 Index, mHLA-DR, and CD14+monocyte Percentage in Different Infection Status in COVID-19 Patients

Zhu M, Cheng J, He L, Li C, Shi B, Jin M, Yu J, Huang J

Journal of Inflammation Research 2025, 18:10099-10110

Published Date: 29 July 2025

An Integrated Machine Learning Framework for Developing and Validating a Diagnostic Model of Hub Genes Related to Lipid Metabolism in Chronic Rhinosinusitis

Xiong P, Liu L, Pi J, Wang J, Lu T, Ke X, Jiang Y, Shen Y, Yang Y

Journal of Inflammation Research 2025, 18:10081-10098

Published Date: 30 July 2025

Astragaloside IV Attenuates Chronic Prostatitis by Activating Keap1/Nrf2/HO-1 Pathway: Suppressing Ferroptosis and Enhancing Antioxidant Defense

Shi J, Xuan Y, Zhang Q, Chen J, Zhu W, Zhang H, Duan Y

Journal of Inflammation Research 2025, 18:10061-10079

Published Date: 29 July 2025

Correlation Between Peripheral Blood Immune Cell Distribution and Disease Severity and Prognosis in Multiple Sclerosis Patients

Liu PJ, Yuan P, Liu SP

Journal of Inflammation Research 2025, 18:10051-10059

Published Date: 28 July 2025

Multi-Omics Analysis Combined with Machine Learning Identified FABP4 in Smooth Muscle Cells as a Pathogenic Factor in Atherosclerosis

Wang Y, Shang T, Cai R, Wang C

Journal of Inflammation Research 2025, 18:10029-10049

Published Date: 26 July 2025

Predictive Significance of the Monocyte-to-High-Density Lipoprotein Cholesterol Ratio in Post-Percutaneous Coronary Intervention Contrast-Induced Nephropathy Among Patients with Coronary Artery Disease

Lin A, Peng Y, Shao J, Chen L, Lin Y

Journal of Inflammation Research 2025, 18:10015-10028

Published Date: 26 July 2025

A Pan-Cancer Analysis of Natriuretic Peptide Receptor 3 (NPR3) with Clinical Cohort and in vitro Validation

Liu Y, Liu J, Li Y, Zhao Z, Lyu D, Dong K, Wei M, Huang R, Lu B, Pan X

Journal of Inflammation Research 2025, 18:9989-10013

Published Date: 26 July 2025

Disulfidptosis-Related Genes as Novel Biomarkers and Therapeutic Targets in Dilated Cardiomyopathy

Bo X, Fan J, Xu S, Zeng Y, Xu A, Wang X, Wang H, Kang P, Fu Y, Fan H, Tan X, Zhou Y

Journal of Inflammation Research 2025, 18:9967-9988

Published Date: 25 July 2025

PM2.5 Induces Cell-Specific Transcriptomic Alterations in the Lungs of Juvenile Mice

Gui B, Li Y, Li K, Wang J, Fan W, Li L, Wu Q, Chen H

Journal of Inflammation Research 2025, 18:9951-9966

Published Date: 25 July 2025

Association of Neutrophil Percentage-to-Albumin Ratio with All-Cause and Cardiovascular Mortality in Maintenance Hemodialysis Patients: A Retrospective Study

Jiang H, Yuan M, Li L, Zhou S, Huang L, Su L, Bai Y

Journal of Inflammation Research 2025, 18:9935-9949

Published Date: 26 July 2025

Altered Nasal Microbiota-Metabolome Interactions in Allergic Rhinitis: Implications for Inflammatory Dysregulation

Ma Q, Wang N, Zheng X, Liu J, Che Y, Wang J

Journal of Inflammation Research 2025, 18:9919-9934

Published Date: 26 July 2025

The Relationship Between Advanced Lung Cancer Inflammation Index and Adverse Clinical Outcomes in Patients with Myocardial Infarction with No-Obstructive Coronary Arteries

Zhao HW, Wang CF

Journal of Inflammation Research 2025, 18:9907-9917

Published Date: 26 July 2025

Sepsis with Cancer is Marked by a Dysregulated Myeloid Cell Compartment: A Pilot Study [Corrigendum]

Qi W, Han J, Cao Y, Yu H, Hao J, Yin N, Zang X, Zhao L, Chen W, Chen C, Zeng H, Liu J, Li A

Journal of Inflammation Research 2025, 18:9905-9906

Published Date: 25 July 2025

A Nomogram Based on Immune Inflammation Indicators for Rotaviral Diarrhea in Children Under 5 years Old: A Single-Center Retrospective Cohort Study

Chen J, Chen X, Huang X, Liu J, Yu Q

Journal of Inflammation Research 2025, 18:9891-9903

Published Date: 25 July 2025

Deciphering Cuproptosis in Sepsis: Mechanisms, Consequences, and Therapeutic Opportunities

Tan R, Wen K, Zhao T, Guo H, Han X, Wang J, Ge C, Du Q

Journal of Inflammation Research 2025, 18:9879-9890

Published Date: 25 July 2025

Exploring the Importance of ZBP1 in Sepsis: A Mini Review on It’s Mechanisms and Progress

Liu J, Feng J, Hu J, Chen J, Li FX, Lin N

Journal of Inflammation Research 2025, 18:9871-9878

Published Date: 25 July 2025

Targeting the NLRP3-ROS Axis: Disrupting the Oxidative-Inflammatory Vicious Cycle in Intracerebral Hemorrhage

Cao L, Pi W, Zhang Y, Zheng C, Yong VW, Xue M

Journal of Inflammation Research 2025, 18:9849-9870

Published Date: 24 July 2025

Impact of Echinococcus granulosus Cyst Fluid on the Phenotypic Dynamics and Degranulation of RBL-2H3 Mast Cells

Yue Z, Zhou JR, Wang CS, Pu XL, Parehati G, Cao LW, Bayina B, Ye JR

Journal of Inflammation Research 2025, 18:9837-9848

Published Date: 24 July 2025

Protective Effect of Hordenine on Concanavalin A-Induced Hepatic Injury

Liu Y, Wang Y, Jiang M, Zhang Q, Yang M, Sun F, Xu Z, Liu T, Yao J

Journal of Inflammation Research 2025, 18:9823-9835

Published Date: 23 July 2025

Review

Atherosclerosis and Inflammation: Are the Rules of the Game Changing with Biological Therapies?

Bora R, Kılıç AT, Toprak B

Journal of Inflammation Research 2025, 18:9811-9822

Published Date: 24 July 2025

Effects of Emodin on Lung Inflammation and Intestinal Microbes in Chronic Obstructive Pulmonary Disease

Xue J, Zhou Q

Journal of Inflammation Research 2025, 18:9795-9809

Published Date: 23 July 2025

Identifying and Diagnosing Lytic Cell Death Genes in Atherosclerosis Using Machine Learning and Bioinformatics

Zhang G, Ma R, Jin H, Zhang Q, Li W, Ding Y

Journal of Inflammation Research 2025, 18:9767-9793

Published Date: 23 July 2025

Effect and Safety of Finerenone in Patients with IgA Nephropathy

Guo Y, Zhang X, Zhao S, Wang Y, Wang L, Li Q, Yu L, Tang L

Journal of Inflammation Research 2025, 18:9755-9765

Published Date: 23 July 2025

The Improvement of Intestinal Mucosal Epithelial Barrier Integrity by 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]pyridazinone in Rat Experimental Colitis

Szandruk-Bender M, Wiatrak B, Merwid-Ląd A, Dzimira S, Szeląg A, Magdalan JM, Szczukowski Ł, Świątek P, Duda-Madej A, Gębarowski T, Nowak B

Journal of Inflammation Research 2025, 18:9735-9753

Published Date: 22 July 2025

Potential Metabolic Markers in the Tongue Coating of Chronic Gastritis Patients for Distinguishing Between Cold Dampness Pattern and Damp Heat Pattern in Traditional Chinese Medicine Diagnosis

Yuan S, Zhang R, Zhu Z, Zhou X, Zhang H, Li X, Hao Y

Journal of Inflammation Research 2025, 18:9717-9734

Published Date: 23 July 2025

ISLR as a Cuproptosis-Related Predictor and Therapeutic Target in Heart Failure: A Multi-Omics and Bioinformatics Approach

Huang K, Ding S, Xu X, Wang C, Han L

Journal of Inflammation Research 2025, 18:9699-9716

Published Date: 22 July 2025

Role of Ferroptosis in Alveolar Epithelial Cells in Acute Respiratory Distress Syndrome

Sun B, Wang L, Zhang T

Journal of Inflammation Research 2025, 18:9679-9698