Journal of Pain Research

Functional and Structural Characteristics of the Pelvic Floor in Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Huang N, Bao K, Sun W, Yang Z, Shi J, Zha J, Zhang P, Li J, Ma M

Journal of Pain Research 2025, 18:7351-7362

Published Date: 31 December 2025

Moving Beyond One-Size-Fits-All: Charting a Path to Personalized Nonpharmacological and Noninvasive Chronic Pain Management

Xie Q, Goldberg SB, Jacobson N, Rakel D, Quanbeck A

Journal of Pain Research 2025, 18:7335-7349

Published Date: 31 December 2025

Effect of Spinal Cord Stimulation on Skin Temperature in Patients with Neuropathic Pain: An Observational Study

Gehling M, Bertelmann-Barge K, Roth C

Journal of Pain Research 2025, 18:7327-7333

Published Date: 31 December 2025

Long-Term Prognosis of Surgical and Non-Surgical Treatment for Lumbar Spinal Stenosis: A Retrospective Cohort Study

Liu X, Wu Y, Ma P, Xu H, Qiu M, Kang L

Journal of Pain Research 2025, 18:7311-7326

Published Date: 31 December 2025

Modulating Gamma Oscillations in the Anterior Cingulate Cortex with Intermittent Theta Burst Stimulation: Implications for Chronic Non-Specific Low Back Pain

Jiang H, Wang Q, Ye Z, Ding Y

Journal of Pain Research 2025, 18:7299-7309

Published Date: 30 December 2025

Risk Factors and Nomogram-Based Prediction of the Risk of Postherpetic Neuralgia in Patients with Herpes Zoster

Peng B, Min R

Journal of Pain Research 2025, 18:7287-7297

Published Date: 30 December 2025

Association Between Chronic Neck Pain and Increased Risk of Chronic Respiratory Diseases in Middle-Aged and Elderly Chinese Adults: A Cohort Study Based on CHARLS

Yi M, Zhang Z, Li H, Sai J, Li W, Wang Z

Journal of Pain Research 2025, 18:7275-7286

Published Date: 30 December 2025

Pain Relief During Cystoscopic Ureteral Stent Extraction by Transcutaneous Electrical Acupoint Stimulation: A Double-Blinded, Randomized, Controlled Trial

Chen Q, Lian H, Wang J, Chen L, Shi R, Qian M

Journal of Pain Research 2025, 18:7261-7273

Published Date: 30 December 2025

A Study on the Association Between Risk Factors and Psychosocial Factors of Non-Cardiac Chest Pain (NCCP) in Adults Aged 40 and Above Based on 2013-2018 US NHANES Data

Chen Y, Li S, Guo F

Journal of Pain Research 2025, 18:7245-7259

Published Date: 30 December 2025

Network Analysis of Contemporaneous Symptoms and Identification of Core Symptoms in Patients with Lumbar Disc Herniation

Lu H, Shi H, Chen Y, Zhang C, Chen X, Zhang X, Yin X

Journal of Pain Research 2025, 18:7233-7244

Published Date: 30 December 2025

Differential Effects of Cycling Exercise on Pain Types in Patients with Early Parkinson’s Disease: A Subgroup Analysis of a Randomized Pilot Trial

Jun JS, Choi S, Kang N, Park K, Jeon B, Byun K, Kim R

Journal of Pain Research 2025, 18:7225-7232

Published Date: 28 December 2025

Efficacy and Safety of Pulsed Radiofrequency Combined with Platelet-Rich Plasma in the Treatment of Postherpetic Neuralgia: A Systematic Review and Meta-Analysis

Lu Z, Zhao C, Ni H, Yao M

Journal of Pain Research 2025, 18:7213-7224

Published Date: 30 December 2025

Unilateral Percutaneous Curved Kyphoplasty versus Bilateral Percutaneous Kyphoplasty for the Treatment of Single-Level Osteoporotic Vertebral Compression Fractures: A Retrospective Comparative Study

Xie C, Tang H, Liu G, Jin X, Wen SH, Li Y, Chen M, Zhang X

Journal of Pain Research 2025, 18:7199-7212

Published Date: 28 December 2025

Efficacy and Safety Comparison of Ulinastatin versus Flurbiprofen Axetil for Preemptive Analgesia in Reducing Opioid Burden After Total Knee Arthroplasty: A Randomized Controlled Trial [Response to Letter]

Wang D, Li Y

Journal of Pain Research 2025, 18:7195-7197

Published Date: 31 December 2025

Effectiveness of Isokinetic Muscle Strength Training on Knee Osteoarthritis Patients: A Systematic Review with Meta-Analysis

Chang BY, Chen L, Xu HC, Hao JH, Wang HJ

Journal of Pain Research 2025, 18:7179-7193

Published Date: 28 December 2025

Non-Pharmacological and Pharmacological Treatments for Non-Acute Lumbar Disc Herniation: A Protocol for a Multicenter Pragmatic Trial

Kim D, Lee YJ, Yang C, Ahn YJ, Kim S, Lee Y, Cho HW, Han CH, Ha IH

Journal of Pain Research 2025, 18:7167-7178

Published Date: 26 December 2025

Two-Year Outcomes of Lateral Transiliac Sacroiliac Joint Fusion with Porous Threaded Implant

Jung M, Kuhns C

Journal of Pain Research 2025, 18:7159-7165

Published Date: 26 December 2025

Efficacy Comparison of Ultrasound-Guided and Dual-Guided (Ultrasound Plus Nerve Stimulation) Subcostal Quadratus Lumborum Block in Retroperitoneal Laparoscopic Nephrectomy: A Randomized Controlled Trial

Li H, Xu S, Shi R, Shao P, Ma D, Guo R, Jin X, Wang Y

Journal of Pain Research 2025, 18:7149-7158

Published Date: 26 December 2025

The Application of Erector Spinae Plane Block in Chronic Pain Management: From Anatomical Mechanisms to Clinical Innovations

Du S, Xie Q, Liang T, Feng Y

Journal of Pain Research 2025, 18:7139-7148

Published Date: 26 December 2025

The Minimum Clinically Important Difference of the Brief Pain Inventory During the Perioperative Period of Unicompartmental Knee Arthroplasty: A Prospective Observational Study

Tang R, Wan D, Wang Q, Ye J, Tan Y, Yao S, Ma J, Xu C

Journal of Pain Research 2025, 18:7127-7138

Published Date: 25 December 2025

Ginger Moxibustion Activates TRPV1 to Modulate the Locus Coeruleus-Spinal Cord-Uterus Pathway and Alleviates Primary Dysmenorrhea in Rats

Wang X, Yang L, Bi K, Zhou M, Wang D, Zhao Z, Mi S, Li X

Journal of Pain Research 2025, 18:7109-7125

Published Date: 25 December 2025

Carnitine and Other Metabolites in Fibromyalgia a Clinical Perspective on a Mendelian Randomization Study

Hong M, Wang J, Huang X, Xu Q, Xiao Y, Ling K

Journal of Pain Research 2025, 18:7097-7107

Published Date: 25 December 2025

Study Protocol

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Effectiveness of High-Voltage, Long-Duration Pulsed Radiofrequency in the Treatment of Postherpetic Neuralgia in the Elderly: Protocol for a Randomized Clinical Trial

Li W, He L, Lin P, Chen R, Liu R

Journal of Pain Research 2025, 18:7087-7095

Published Date: 24 December 2025

Opioid-Free Anesthesia Alleviates Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy: Study Protocol for a Randomized, Controlled Trial

Li Y, Hao D, Qi X, Song B

Journal of Pain Research 2025, 18:7077-7085

Published Date: 23 December 2025

Intradiscal Biacuplasty Treating Lumbar Degenerative Disc Disease: Long-Term Results of More Than 100 Patients

Yen TH, Huang CH, Chiu YP, Ji HR, Wang YJ, Wu CY, Guo JH, Chuang TY, Chiu CD

Journal of Pain Research 2025, 18:7065-7076

Published Date: 24 December 2025

Digital Cognitive Behavioral Therapy for Insomnia in Cancer Pain Patients: Protocol for a Prospective, Randomized Controlled Trial

Lan X, Hu X, Lan Z, Wang L, He R, Jiang Z

Journal of Pain Research 2025, 18:7053-7063

Published Date: 23 December 2025

Short-Term Efficacy of Vitapex Paste in Single-Visit Root Canal Treatment for Acute Irreversible Pulpitis: A Retrospective Cohort Study

Liu J, Li F, Liang X, Niu J

Journal of Pain Research 2025, 18:7043-7052

Published Date: 23 December 2025

Identification of Pyroptosis-Related Genes in Male Rats with Spared Nerve Injury-Induced Neuropathic Pain

Li W, Hu Z, Lin P, He L, Liu R

Journal of Pain Research 2025, 18:7029-7041

Published Date: 23 December 2025

Compare the Effects of Transversalis Fascia Plane Block versus Intravenous Lidocaine Infusion on the Quality of Early Postoperative Recovery in Patients Undergoing Gynecologic Laparoscopic Surgery

Zhang P, Zhao Y, Mu H, Zhang J, Zhang F, Wang S

Journal of Pain Research 2025, 18:7019-7027

Published Date: 23 December 2025

Comparative Analysis of Paraspinal Muscle Fat Infiltration and Clinical Efficacy Following Single-Level UBD-TLIF versus MIS-TLIF: A Retrospective MRI-Based Study [Corrigendum]

Yan J, Tian M, Wu M, Yuan Z, Fan Y, Wu X, Ni H, Zhao Y, Yu S, He S

Journal of Pain Research 2025, 18:7017-7018

Published Date: 23 December 2025

Commentary on “Working Memory Load-Dependent Cortical Mechanism of Distraction Analgesia in Healthy Individuals: An fNIRS Study” [Letter] [Corrigendum]

Jia T, Li L, Sun J

Journal of Pain Research 2025, 18:7015-7016

Published Date: 22 December 2025

Characteristics of the Pediatric Chronic Pain Service in a Developing Country: A Retrospective Study

Kiatchai T, Mandee S, Panchoowong S, Finley GA

Journal of Pain Research 2025, 18:7005-7014

Published Date: 22 December 2025

Right Hemispheric Neuronal Dysfunction in Cancer Pain: A Resting-State fMRI Exploratory Study

Xu D, Liu Z, Wu Z, Zhang Y, He Y

Journal of Pain Research 2025, 18:6993-7003

Published Date: 22 December 2025

Auricular Plaster Therapy for Preoperative Anxiety in Major Surgery: A Prospective Matched-Cohort Study of Total Knee Arthroplasty and Pancreaticoduodenectomy Patients

Mi Q, Shao Q, Bao F, Zhao X, Zan D, Liu Y, Wang W

Journal of Pain Research 2025, 18:6977-6991

Published Date: 23 December 2025

Acupuncture at Sensitized Acupoints versus Sham Acupuncture for Neck-Type Cervical Spondylosis: Study Protocol for a Randomized Controlled Trial

Li C, Wang J, Shao X, Wu Y, Qu X, Cai J, He L, Yu L, Xu R, Xia Y, Wang R, Zhang L, Qiu Y

Journal of Pain Research 2025, 18:6963-6976

Published Date: 23 December 2025

Investigating Self-Reported Sensory Intolerance and Perceptual Ability Across Sensory Modalities in Fibromyalgia

Shepherd H, Poliakoff E, Brown CA, Brown RJ

Journal of Pain Research 2025, 18:6947-6961

Published Date: 21 December 2025

Effectiveness of Non-Pharmacological Interventions for Pain Management After Laparoscopic Cholecystectomy: A Systematic Review and Network Meta-Analysis

Lei T, Peng Y, Liu Y, Xie Y, Wang J

Journal of Pain Research 2025, 18:6933-6946

Published Date: 20 December 2025

Data Inconsistency, Cost Paradox, and Learning Curve Bias: Critical Concerns Regarding the EUBS Study [Letter]

Li T, Lv L

Journal of Pain Research 2025, 18:6931-6932

Published Date: 20 December 2025

Dynamic Ultrasound Quantification of Acupuncture-Induced Multifidus Recovery in Lumbar Disc Herniation

Zhang J, Xu J, Wu Q, Yi X

Journal of Pain Research 2025, 18:6921-6929

Published Date: 19 December 2025

Targeting Kinesiophobia After Thoracic Surgery with an Integrated Protection Motivation and Exposure Intervention: A Randomized Controlled Trial

Peng J, Luo Y, Feng L, Xiao J, Feng F, Zheng Y, Bao L, Yang S, Wu X

Journal of Pain Research 2025, 18:6911-6920

Published Date: 19 December 2025

Determining the Effective Dose of Oliceridine Compounded with Propofol for Painless Hysteroscopy: A Prospective Modified Dixon Sequential Dose-Finding Study

Yang K, Yuan Q, Huang H, Wang L, You J, Liu Q, Zhou Y, Luo Y, Liu Q

Journal of Pain Research 2025, 18:6903-6910

Published Date: 18 December 2025

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Assessment of the Burden of Chronic Neck and/or Shoulder Pain on Quality of Life Among Saudi Adults: A Cross-Sectional Study

Jareebi MA, Abutaleb YB, Mobarki OA, Serafi RA, Alhajji SIA, Ayob SM, Alshahrani MS, Binakrash SS, Hakami IA, Ryani MA, Bahri AA, Maslamani YA, Masmali AA, Aqeeli AA, Alasmari M

Journal of Pain Research 2025, 18:6885-6901

Published Date: 19 December 2025

The Association of Chronic Pain and Complementary Health Approach Usage: A Comprehensive Analysis Adjusting for Demographics

Agostini K, Acheson AD, Agnello R, Ortiz R, Motyka TM

Journal of Pain Research 2025, 18:6869-6884

Published Date: 19 December 2025

LncRNA-Associated ceRNA Network in the Spinal Cord Reveals the Central Mechanism of Chronic Inflammatory Visceral Pain

Li X, Wang X, Dong X, Li Z, Lu Y, Liu L, Yang G, Hong J, Yang Y, Zhang C, Wu H, Zhang D, Ma X

Journal of Pain Research 2025, 18:6853-6868

Published Date: 17 December 2025

Effect of Contralateral Acupuncture (Geoja Technique) in Musculoskeletal Disorders Stratified by Pulse Strength Differences: A Retrospective Study [Response to Letter]

Lee D, Park S, Kim G, Baek Y, Park YC

Journal of Pain Research 2025, 18:6849-6852

Published Date: 18 December 2025

Analgesic Efficacy and Tolerability of Amitriptyline versus Mianserin in Chronic Low Back Pain: A Randomised, Double-Blind, Controlled Pilot Trial

Wangnamthip S, Eiamtanasate S, Saisavoey N, Sathienluckana T, Suthisiltham L, Panchoowong S, Tipapakoon I, Euasobhon P, Jensen MP, Srirojanakul W

Journal of Pain Research 2025, 18:6829-6847

Published Date: 17 December 2025

Comment on “Efficacy and Safety Comparison of Ulinastatin versus Flurbiprofen Axetil for Preemptive Analgesia in Reducing Opioid Burden After Total Knee Arthroplasty: A Randomized Controlled Trial” [Letter]

Wu M, Ye Y

Journal of Pain Research 2025, 18:6827-6828

Published Date: 16 December 2025

Efficacy and Safety of Acupuncture Combined with Conventional Drug Therapy for the Treatment of Cancer-Induced Bone Pain: A Network Meta-Analysis of Randomized Controlled Trials

Wang X, Shen Q, Hu X, Yu X, Erasmus SR, Gong L, Liu J, Fan W, Liang Y

Journal of Pain Research 2025, 18:6807-6826

Published Date: 17 December 2025

Factors Associated with Depression, Anxiety, and Sleep Disturbance Among Patients with Moderate-to-Severe Chronic Pain: A Multicenter Cross-Sectional Study

Guo SQ, Wang LQ, Tu JF, Yang JW, Shi GX, Yan SY, Li T, Fu Y, Zhou ZY, Ji CC, Hu H, Han LF, Liu M, Xu SF, Li M, Liu LY, Chen F, Liu CZ

Journal of Pain Research 2025, 18:6791-6805

Published Date: 16 December 2025

Effectiveness of Acupotomy Combined with Topical Diclofenac for Knee Osteoarthritis: A Randomized Controlled Trial

Du K, Cheng WZ, Li A, Zhang CY, Yan SY, Han F, Guo R, Chen P, Du WS, Zuo YL, Zuo QH, Li SM

Journal of Pain Research 2025, 18:6779-6790

Published Date: 17 December 2025

The Impact of Patient-Controlled Analgesia Combined with Self-Management Training on Pain Modulation in Diabetic Patients with Chronic Knee Pain

Zhao X, Huang Z, Su Z, Zhou H, Chen L

Journal of Pain Research 2025, 18:6769-6777

Published Date: 16 December 2025

Factors in Surgical Placement and System Design to Reduce Pocket Awareness and Optimize the User Experience of Spinal Cord Stimulators – A Comprehensive Review

Gish B, Al-Asadi Z, Tisler AT, Mata R, Chopra H, Garcia RA, Schatman ME, Tieppo Francio V, AlFarra T, Bracero L, Karcz M, Robinson CL, Shah A, Moreira A, Sciascia AD, Deer T

Journal of Pain Research 2025, 18:6749-6768

Published Date: 14 December 2025

Commentary on “Working Memory Load-Dependent Cortical Mechanism of Distraction Analgesia in Healthy Individuals: An fNIRS Study” [Letter]

Jia T, Li L, Sun J

Journal of Pain Research 2025, 18:6745-6747

Published Date: 12 December 2025

Flow-Induced Analgesia: A Conceptual Review of Biopsychosocial and Neurobiological Mechanisms of Pain Modulation

Gromakovskis V, Gūtmanis MG

Journal of Pain Research 2025, 18:6723-6743

Published Date: 12 December 2025

Original Research

Headache and Facial Pain

Episodic Migraine Pain Curves: Real-Time Smartphone-Based Analysis and Clinical Implications

Gago-Veiga AB, Gonzalez-Martinez A, Quintas S, Vieira A, Gálvez-Goicuría J, Sanz-García A, Ayala JL, Sobrado M, Vivancos J, Pagan J

Journal of Pain Research 2025, 18:6711-6722

Published Date: 11 December 2025

Chloroprocaine ED50 and ED95 for Propofol Injection Pain Prevention: Dixon’s Sequential Method

Lai P, Yang X, Yang X, Xuan Q, Fang Y, He Z, Chen B, Yin G

Journal of Pain Research 2025, 18:6699-6709

Published Date: 10 December 2025

A Primer on Anatomy, Biophysics, Pathology, Imaging and Treatment of the Intervertebral Disc and the Anterior Spinal Column: The Discogenic, Intervertebral, Spinal Column (DISC) ASPN Workgroup

Grider JS, Deer TR, Beall DP, Murphy MZ, Fleming JW, Falowski SM, Mallard CJ, Ramawad HA, Garcia RA, Latif U, Vu CM, Christopher A, Harned ME, Patel RG, Shah AJ, Cowan IM, Jarzombek K, Tate JL, Khatri N, Graca MJ, Karcz MK, Davis TT, Barkoh K, Clerk-Lamalice O, Durkin B, Malinowski MN, Gross DK, Hedman T, Green M, Dorsi MJ, Amirdelfan K, Sayed D

Journal of Pain Research 2025, 18:6651-6698

Published Date: 11 December 2025

Real-World Effectiveness and Tolerability of Low Dose Naltrexone to Treat Chronic Pain: A Retrospective Cohort Study of One Pain Physician’s Practice

Aalto H, Paul S, McEwen V

Journal of Pain Research 2025, 18:6637-6649

Published Date: 10 December 2025

Assessment of Safety and Efficacy of Full-Endoscopic Ultrasonic Bone Scalpel for Cervical Spondylotic Radiculopathy

Wang ZF, Hu MZ, Liu ZJ, Bu JH, He B, Zhang Q, Xu L, Gao J, Ma C, Liu GW

Journal of Pain Research 2025, 18:6627-6636

Published Date: 9 December 2025

A Retrospective Follow-Up Study of Satisfaction in Patients Undergoing Unicompartmental Knee Arthroplasty: A 3-Month Postoperative Analysis

Wang M, Cao X, Zhang X, Liu H

Journal of Pain Research 2025, 18:6617-6625

Published Date: 9 December 2025

Effect of Succinylcholine on Postoperative Sore Throat in Hysteroscopic Surgery with Laryngeal Mask Airway (LMA): A Randomized Trial

Deng X, Hao X, Bi Y, Li H, Lin X

Journal of Pain Research 2025, 18:6607-6616

Published Date: 8 December 2025

Circulating MicroRNA Biomarkers for Chronic Pain and Acupuncture Response: An Exploratory High-Dimensional Small-Sample Study

Kang IH, Kim SN

Journal of Pain Research 2025, 18:6591-6605

Published Date: 6 December 2025

No Evidence for a Causal Association Between Depression and Herpes Zoster or Post-Herpetic Neuralgia: A Mendelian Randomization Study

Zhang X, Chen Y, Lin J, Guo W, Zhou H, Yang X, Zhao Q

Journal of Pain Research 2025, 18:6579-6589

Published Date: 6 December 2025

Severe Neck and Low Back Pain Predicts Severe Pain 5 Years Later in Older Men: A Cohort Study

Damm H, Rosengren BE, Jehpsson L, Ohlsson C, Ribom EL, Mellström D, Karlsson MK

Journal of Pain Research 2025, 18:6563-6577

Published Date: 6 December 2025

Development and External Validation of a Nomogram for Predicting Pain Risk Post-Transperineal Prostate Biopsy Using Multi-Parameter Analysis

Xu Y, Li X, Zhang Y, Xue P

Journal of Pain Research 2025, 18:6545-6561

Published Date: 5 December 2025

Causal Relationships Between Neuropathic Pain and Alzheimer’s Disease: A Multi-Omics Mendelian Randomization Study with Exploratory Evidence of a Potential Protective Role of Diabetic Neuropathy

Li X, Zhang C, Liu D, Shang H, Wang K, Lin X, Zheng J

Journal of Pain Research 2025, 18:6527-6544

Published Date: 6 December 2025

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Sex-Specific Association Between Vitamin D Insufficiency and Burning Pain in Herpetic Neuralgia: A Prospective Cohort Study

Zhao W, Li Z, Ju J, Liu J, Peng X, Chu T, Ren J, Tu Y, Gao F

Journal of Pain Research 2025, 18:6515-6525

Published Date: 5 December 2025

Original Research

Opioids and Substance Abuse

Risk of Opioid Use Disorder in Surgical Patients with Medicaid and Associations with Prescription Opioid Dose and Duration

Doan LV, Hung AM, Williams NT, Olfson M, Rudolph KE

Journal of Pain Research 2025, 18:6505-6514

Published Date: 5 December 2025

Gabapentinoids-Induced Rhabdomyolysis/Myopathy: Clinical Characteristics, Management, Outcomes, and Critical Safety Alerts

Liu M, Long M, Zhou X

Journal of Pain Research 2025, 18:6491-6503

Published Date: 4 December 2025

Effects of Transcutaneous Electrical Acupoint Stimulation on Postoperative Acute Visceral, Incisional, and Low Back Pain and Recovery in Patients Undergoing Laparoscopic Hysterectomy: A Randomized Controlled Trial

Zhang Y, Dai Q, Zhang J, Wang J, Zhuang X, Zhang A, Huang L, Du W

Journal of Pain Research 2025, 18:6477-6489

Published Date: 4 December 2025

Radiofrequency Ablation of the Medial Branch Nerves for Posterior Element Pain in Chronic Vertebral Compression Fractures: An Anatomical Review and Retrospective Case Series

Sanghvi CD, Gordon AT, Singh N, Willard FH, Ren Y, Wilson MD, Copenhaver D

Journal of Pain Research 2025, 18:6463-6475

Published Date: 2 December 2025

Effects of Transcutaneous Electrical Acupoint Stimulation on Recovery After Gynecological Laparoscopic Surgery: A Randomized, Single-Blind, Controlled Trial

Zheng J, Zhou H, Diao Y, Song P, Yi Z, Guo X, Li L

Journal of Pain Research 2025, 18:6449-6462

Published Date: 3 December 2025

Comparative Cardiovascular Safety of Duloxetine and Gabapentin in Patients with Hip Osteoarthritis

Moon S, Choo E, Choi YJ, Shin S

Journal of Pain Research 2025, 18:6437-6448

Published Date: 3 December 2025

Shared Genetic Architecture of Obstructive Sleep Apnea and Neck Pain: A Large-Scale Genome-Wide Association Study

Yang F, Zhu D, Yu R, Zhang Z, He J

Journal of Pain Research 2025, 18:6423-6436

Published Date: 1 December 2025

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

The Neural Mechanisms of rTMS and Placebo Effects in Trigeminal Neuralgia: Evidence From fMRI Network Dynamics

Liu Y, Chen H, Chen S, Huang L, Jin Z, Guo X, Jiang X, Wang Y

Journal of Pain Research 2025, 18:6413-6422

Published Date: 2 December 2025

Letter Comments on: Effect of Contralateral Acupuncture (Geoja Technique) in Musculoskeletal Disorders Stratified by Pulse Strength Differences: A Retrospective Study [Letter]

Qiu S, Chen M

Journal of Pain Research 2025, 18:6409-6411

Published Date: 28 November 2025

Therapeutic Exercise Progression in Patients with Nonspecific Low Back Pain: A Systematic Review

Tuninetti A, Barbari V, Storari L, Bisconti M, Piano L, Dunning J, Mourad F, Maselli F

Journal of Pain Research 2025, 18:6397-6407

Published Date: 29 November 2025

Original Research

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Real-World Outcomes of Spinal Cord Stimulation: A Consecutive Institutional Experience with 505 Trials, Trial-to-Implant Ratio, Long-Term Efficacy, and Explantation Risk Factors

Gheith R, Wortmann M, Najjar M, Oliver C, Whitlow B, Raterman B, Shackelford KR

Journal of Pain Research 2025, 18:6381-6395

Published Date: 28 November 2025

Early Outcomes of Unilateral Biportal Endoscopic Decompression for Adjacent Segment Disease After Lumbar Fusion

Pi W, Ye L, Gong B, Liu Y, Liu W, Chen H, Zhao H

Journal of Pain Research 2025, 18:6371-6379

Published Date: 28 November 2025

“Preoperative Central Sensitization in Pilon Fracture Outcomes: Considerations on Grouping, Analgesia, and Data Interpretation” [Response to Letter]

Liang J, Zan Q, Cao S, Wang H, Liu G, Yang W, Zhang S, Li Y, Xu J

Journal of Pain Research 2025, 18:6369-6370

Published Date: 28 November 2025

Mechanotransduction Pathways in Massage Therapy: CB1/Piezo2 Receptor Crosstalk Modulates Myocellular Anti-Inflammatory Responses

Liu Q, He W, Li M, Li Z, Wu C

Journal of Pain Research 2025, 18:6359-6367

Published Date: 27 November 2025

Study Protocol

Acute Pain and Perioperative Care

The Effect of Transcutaneous Electrical Acupuncture Stimulation on Postoperative Pain Control and Mobility in Patients Undergoing Percutaneous Endoscopic Lumbar Discectomy: Study Protocol for a Prospective Randomized Trial

Hu CF, Meng FX, Luo X, Chen BY

Journal of Pain Research 2025, 18:6345-6357

Published Date: 26 November 2025

The American Society of Pain and Neuroscience (ASPN) Guidelines for Advanced Practice Providers in Interventional Spine and Pain Management Practice

Grillo C, Abd-Elsayed A, Yousef TA, Misercola B, Hussaini Z, Rabii M, Comer A, Durkin K, McGinn P, Deer T

Journal of Pain Research 2025, 18:6319-6344

Published Date: 26 November 2025

Preoperative Central Sensitization in Pilon Fracture Outcomes: Considerations on Grouping, Analgesia, and Data Interpretation [Letter]

Gao B

Journal of Pain Research 2025, 18:6317-6318

Published Date: 26 November 2025

Effectiveness of Acupuncture for Neck Pain: Systematic Review and Meta‑analysis with Trial Sequential Analysis

Xie CR, Zhang ZY, Tao QF, Luo XD, Fu QX, Gao L, Wang T, Ouyang X, Yan Q, Sun MS, Wang X, Liang FR, Zheng H, Zhao L

Journal of Pain Research 2025, 18:6297-6316

Published Date: 25 November 2025

Electroacupuncture for the Subacute Stage of Lumbar Disc Herniation: A Randomized Controlled Trial Protocol with EEG

Yu H, Zhang J, Zhang D, Zhao L, Wu S, Zhang L, Yang Y, Li G

Journal of Pain Research 2025, 18:6279-6295

Published Date: 26 November 2025

Acupuncture Modalities Differentially Modulate Pain and Joint Damage in a Rat Model of Knee Osteoarthritis [Response To Letter]

Kamau VN, Yang S, Lee G, Kim JH

Journal of Pain Research 2025, 18:6275-6277

Published Date: 26 November 2025

Original Research

Pre-Clinical/Scientific

Modulatory Effects of “Minor” Cannabinoids in an in vitro Model of Neuronal Hypersensitivity

Anand U, Anand P, Sodergren MH

Journal of Pain Research 2025, 18:6259-6274

Published Date: 24 November 2025

Original Research

Pain Education and Early Career Investigators

Pain Knowledge, Attitudes, and Beliefs Among Final-Year Physiotherapy and Occupational Therapy Students in Jordan: A Cross-Sectional Study

Muhsen A, Madi M, Wshah A, Obaidat SM, Bin Sheeha B, Shallan A, Yabroudi MA, Altubasi I, Altaim TA

Journal of Pain Research 2025, 18:6243-6257

Published Date: 22 November 2025

Comparative Efficacy of Needling and Non-Needling Therapies for Temporomandibular Disorders: A Bayesian Network Meta-Analysis

Ding X, Liao S, Li T, Qu W, Nie M

Journal of Pain Research 2025, 18:6225-6242

Published Date: 22 November 2025

Improving the Relationship Between the Neuromodulation Industry and Academia: Commentary and Strategy

Schatman ME, Adams DA, Wahezi SE

Journal of Pain Research 2025, 18:6221-6224

Published Date: 20 November 2025

Chronic Post-Surgical Pain After Hip and Knee Arthroplasty: An Update on Mechanisms, Risk Factors, and Interventional Treatment Modalities

Banks DW, Park H, Oehlermarx W, Suarez M, Broachwala M, D’Souza RS, Reddy R

Journal of Pain Research 2025, 18:6205-6219

Published Date: 20 November 2025

Efficacy of Dexmedetomidine as an Adjuvant to Ropivacaine for Intercostal Nerve Block in Elderly Patients Undergoing Video-Assisted Thoracoscopic Esophagectomy: A Randomized Double-Blinded Trial [Letter]

Xu J, Xu Y

Journal of Pain Research 2025, 18:6201-6203

Published Date: 20 November 2025

Comment on “Acupuncture Modalities Differentially Modulate Pain and Joint Damage in a Rat Model of Knee Osteoarthritis” [Letter]

Wang M, Ye X

Journal of Pain Research 2025, 18:6197-6200

Published Date: 20 November 2025

AI-Assisted Knee Infrared Imaging Based Acupuncture for Treating Knee Osteoarthritis: A Randomized Controlled Study Protocol

Yang M, Qiu F, Xie X, Tao L, Zheng W, Wu Y, Xu Z, Xue Y, Cao Y

Journal of Pain Research 2025, 18:6181-6195

Published Date: 19 November 2025

Comparative Effectiveness of Pharmacological, Non-Pharmacological, and Combined Strategies for Pain Relief During Colonoscopy: A Bayesian Network Meta-Analysis of Randomized Trials

Huang X, Tian S, Xu L, Chen J, Wang H, Mai T, Shi L, Wang H, Cai M, Fang F

Journal of Pain Research 2025, 18:6165-6179

Published Date: 19 November 2025

Effect of Contralateral Acupuncture (Geoja Technique) in Musculoskeletal Disorders Stratified by Pulse Strength Differences: A Retrospective Study

Park S, Lee D, Kim GW, Cho FY, Kim Y, Kim Y, Kim G, Baek Y, Park YC

Journal of Pain Research 2025, 18:6149-6163

Published Date: 17 November 2025

“The Fact [Is] That There Is No Easy Way”. A Qualitative Study of the Experiences of Aotearoa New Zealand Clinicians with Opioid Tapering for Chronic Non-Cancer Pain

Fu R, Bean D, Te Morenga L, Frei D, Devan H

Journal of Pain Research 2025, 18:6137-6147

Published Date: 18 November 2025

Clinical Efficacy and Safety of Auricular Acupuncture for Migraine: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Zheng S, Liu L, He X

Journal of Pain Research 2025, 18:6125-6135

Published Date: 18 November 2025

Anatomical and Technical Considerations of CT-Guided C1-C2 Lateral Joint Injections: Technique, Pitfalls, and Risks

Mohajer B, Qazi ZN, Carrino JA, Chazen JL, Schatman ME, Yoon ES

Journal of Pain Research 2025, 18:6111-6124

Published Date: 17 November 2025

ARHGAP17 and VEGFB as Biomarkers for Electroacupuncture in Rheumatoid Arthritis: Potential and Unresolved Questions [Letter]

Xu Y, Luo L, Wang Z, Liu X

Journal of Pain Research 2025, 18:6109-6110

Published Date: 15 November 2025

Long-Term Refined Paraspinal Muscle Exercises Combined with ERAS Protocol Enhance Postoperative Recovery Following Lumbar Fusion Surgery

Zhou X, He Z, Qi Y, Zhang X, Li J, Longzhu J, Yang J, Ma Y, Zhou F, Zhang F, Fang T, Zheng F

Journal of Pain Research 2025, 18:6097-6107

Published Date: 15 November 2025

A Commentary on “Efficacy and Potential Mechanisms of Yi-Ping Lin Circum-Knee Acupuncture in the Treatment of Knee Osteoarthritis” [Letter]

Liu H

Journal of Pain Research 2025, 18:6095-6096

Published Date: 14 November 2025

Pain Management Approaches for Robotic-Assisted Thoracic Surgery: A Retrospective Analysis

Semyonov MA, Shmueli M, Smirnov A, Dubilet M, Refaely Y, Ruderman LN, Maron P, Binyamin Y, Brotfain E, Zlotnik A, Frank D

Journal of Pain Research 2025, 18:6085-6093

Published Date: 14 November 2025

Focused Extracorporeal Shock Wave Therapy for Hemiplegic Shoulder Pain: A Randomized Crossover Pilot Study in Stroke Patients

Kim H, Hwang SSS, Baik H, Lim I, Choi S, Jeon H, Shin S, Kim M

Journal of Pain Research 2025, 18:6073-6083

Published Date: 12 November 2025

Patient-Reported Satisfaction with Non-opioid and Opioid Pain Control is Comparable Following Common Orthopedic Procedures: A Prospective Cohort Study

Bever TE, An C, Sarathy A, Callas P, Ziino C, Fujii MH

Journal of Pain Research 2025, 18:6065-6072

Published Date: 13 November 2025

Unexpected Role of TNFα Signaling in the Resolution of Postoperative Pain in Mice

Laumet S, Edwards AM, Inyang KE, Laumet G

Journal of Pain Research 2025, 18:6057-6063

Published Date: 12 November 2025

Evaluating the Content Validity of the Modified Neuropathy Total Symptom Score-6 Self-Administered (mNTSS-6-SA) in a Painful Diabetic Peripheral Neuropathy Population

Gerould H, Mangrum R, Robinson RL, Schantz K, Bryant A, Delbecque L, Behrend B, Price KL, Stauffer VL, Seçinti E

Journal of Pain Research 2025, 18:6045-6055

Published Date: 12 November 2025

A Retrospective Study of Ultrasound-Guided C2 Transverse Process Injection with Myofascial Release for Cervicogenic Headache

Hao L, Guo Y, Song L, Zhang L, Mi J

Journal of Pain Research 2025, 18:6037-6044

Published Date: 11 November 2025

Individual Autonomic Profiles Influence Brain–Heart Connectivity in Tonic Pain

Aulenkamp JL, Nedergaard RB, Niazi IK, Liao D, Kuhlmann L, Rojas F, Rasool K, Phillips AE, Yadav D, De-Madaria E, Hegyi P, Garg P, Olesen SS, Jagannath S, Hagn-Meincke R, Hajnády Z, Brock C, Drewes AM

Journal of Pain Research 2025, 18:6023-6036

Published Date: 11 November 2025

Microglia’s Phenotypic Heterogeneity in Pain Pathogenesis and Electroacupuncture Analgesia: Mechanisms and Therapeutic Potential

Ji D, Lyu Z, Erasmus S, Wu Y, Li X, Chen X, Fang J, Du J, Fang J, Zhou J, Liang Y

Journal of Pain Research 2025, 18:6007-6022

Published Date: 11 November 2025

Different Acupuncture Therapies Combined with Sulfasalazine for the Treatment of Ankylosing Spondylitis: Bayesian Network Meta-Analysis

Han K, Yu M, Chen J, Wang S

Journal of Pain Research 2025, 18:5991-6006

Published Date: 8 November 2025

Consensus Guidelines for the Use of Peripheral Nerve Stimulation in the Treatment of Chronic Pain and Neurological Diseases: A Neuron Project from the American Society of Pain and Neuroscience

Latif U, Moghim R, Valimahomed A, Lam CM, Abd-Elsayed A, Gulati A, Aman MM, Desai MJ, Dickerson DM, Tieppo Francio V, Gilmore C, Gish B, Hah JM, Hunter C, Ilfeld BM, Kalia H, Lester D, Li S, Mata R, Naidu R, Ottestad E, Pritzlaff SG, Schatman ME, Sheth SJ, Slavin KV, Suvar T, Yalamuru B, Staats PS, Sayed D, Deer TR

Journal of Pain Research 2025, 18:5949-5990

Published Date: 7 November 2025

Acupotomy Improves Synovial Hypoxia, Synovitis and Angiogenesis in KOA Rabbits [Retraction]

Guo Y, Xu Y, He M, Chen X, Xing L, Hu T, Zhang Y, Du M, Zhang D, Zhang Q, Li B

Journal of Pain Research 2025, 18:5947-5948

Published Date: 8 November 2025

Murottal and Classical Music Effect on Pain: Clinical Trial

Prihatno MR, Perkasa G, Prihartini H, Suryani S, Cahyono ID

Journal of Pain Research 2025, 18:5941-5946

Published Date: 7 November 2025

Biological Mechanisms and Clinical Challenges of Platelet-Rich Plasma in Chronic Musculoskeletal Pain: From Standardized Preparation to Multi-Omics-Guided Precision Therapy

Zhou H, Huang Q, Chen Y, Wang J, Jiang H

Journal of Pain Research 2025, 18:5931-5939

Published Date: 7 November 2025

Clinical Trial Report

Pediatric Pain

Impact of Ultrasound-Guided Rectus Abdominis Sheath Block on Analgesia and Agitation During the Awakening Period in Children Undergoing Single-Incision Laparoscopic Inguinal Hernia Repair: A Randomized Clinical Trial

Chen A, Hao R, Wang C, Gu C, Xu X

Journal of Pain Research 2025, 18:5919-5929

Published Date: 7 November 2025

Advanced Age as a Consideration in Spinal Cord Stimulation

McCormick RJ, Schatman ME, Brenner GJ

Journal of Pain Research 2025, 18:5911-5918

Published Date: 7 November 2025

Ziconotide as an Opioid Rescue: Economic, Clinical, and Subgroup Considerations [Letter]

Gan H, Zhang Y, Yang C

Journal of Pain Research 2025, 18:5909-5910

Published Date: 7 November 2025

Critical Methodological Concerns: Enhancing Rigor in “Research on the Developmental Trajectory of Movement-Evoked Pain After Knee Arthroplasty” [Letter]

Zhang K, Wang JW, Liu JT

Journal of Pain Research 2025, 18:5907-5908

Published Date: 7 November 2025

Efficacy and Potential Mechanisms of Yi-Ping Lin Circum-Knee Acupuncture in the Treatment of Knee Osteoarthritis

Huang L, Deng X, Jin Y, Li J, Wu X, Xiong Y, Guo S, Yan S, Lu S, Chen D

Journal of Pain Research 2025, 18:5891-5906

Published Date: 7 November 2025

Efficacy and Safety of Splanchnic Nerve Neurolysis via the Transdiscal Approach Using CT/Ultrasound Dual-Guided Posterior Approach in the Management of Upper Abdominal Cancer Pain: A Retrospective Analysis

Ma L, Wang R, Li L

Journal of Pain Research 2025, 18:5881-5890

Published Date: 7 November 2025

Efficacy and Safety Comparison of Ulinastatin Versus Flurbiprofen Axetil for Preemptive Analgesia in Reducing Opioid Burden After Total Knee Arthroplasty: A Randomized Controlled Trial

Wang D, Meng Y, Li Z, Wu J, Han T, Li Y, Li Y

Journal of Pain Research 2025, 18:5867-5880

Published Date: 6 November 2025

Causal Association of Alzheimer’s Disease with Low Back Pain: A Mendelian Randomization Study

Li Y, Zhao S, Chen X, Wang Z, Liang X, Liu Y, Dong Y

Journal of Pain Research 2025, 18:5857-5865

Published Date: 4 November 2025

Original Research

Integrative/Acupuncture

Clinical Outcomes of Integrative Korean Medicine Treatment in Patients with Neck Pain Following Cervical Disc Surgery: A Multi-Center Retrospective Study

Bong SY, Kang KR, Kwon TH, Go MS, Lee CY, Yeom SC, Lee YJ, Kim D, Ha IH

Journal of Pain Research 2025, 18:5843-5856

Published Date: 5 November 2025

Quadratus Lumborum Block for Pain Management After Colorectal Surgery: Systematic Review and Meta-Analysis of Analgesic and Opioid-Sparing Effects

Han C, Wang Y, Tan H

Journal of Pain Research 2025, 18:5827-5841

Published Date: 3 November 2025

The Analgesic Effect of Low-Dose S(+)-Ketamine in Knee Joint Replacement: A Randomized Controlled Trial

Deng SY, Song X, Chen LN, Zhao F, Guo L

Journal of Pain Research 2025, 18:5815-5826

Published Date: 4 November 2025

Restorative Neurostimulation for Patients with Mechanical Chronic Low Back Pain and Impaired Neuromuscular Control of the Lumbar Spine | A New Treatment Paradigm

Gilligan CJ, Chavda AS, Ho JS, Lee DW, Langhorst M, Yih ET, Amann M

Journal of Pain Research 2025, 18:5799-5813

Published Date: 4 November 2025

Comment on “Efficacy and Safety of Acupuncture and Acupuncture-Combined Therapies in the Treatment of Sciatica Caused by Lumbar Disc Herniation: A Network Meta-Analysis” [Letter]

Tang Y, Chen B

Journal of Pain Research 2025, 18:5797-5798

Published Date: 4 November 2025

Evaluation of Tuina Combined with Medicated Oil in Non-Specific Low Back Pain Treatment: A Randomized Clinical Trial

Wang S, Yuan M, Guo G, Nguyen TTT, Zheng Y, Yin Z, Wang Y, Yao F, Wang G, Xu H

Journal of Pain Research 2025, 18:5781-5796

Published Date: 3 November 2025

Druggable Genome-Wide Mendelian Randomization Identifies Distinct Therapeutic Targets for Low Back Pain, Intervertebral Disk Degeneration, and Sciatica

Sun A, Li Z, Du Y, Liu H, Zhan Q, Liu Z

Journal of Pain Research 2025, 18:5769-5780

Published Date: 4 November 2025

Efficacy and Safety of Electroacupuncture for Postherpetic Neuralgia and Biomarker Evaluation: A Study Protocol for a Multicenter, Randomized Trial

Yu Q, Wang X, Wu J, Zhang Q, Ying X, Ou L, Hu H, He K, Wu L, Jin Z, Shentu J, Dai H, Ma R, Hu Q, Han D

Journal of Pain Research 2025, 18:5753-5768

Published Date: 1 November 2025

Fu’s Subcutaneous Needling for Pain: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Gong X, Wu F, Guo Z, Li N, Wang Z, Liu D

Journal of Pain Research 2025, 18:5739-5752

Published Date: 31 October 2025

A Conceptual Model of Patient Experiences of Painful Diabetic Peripheral Neuropathy to Support Clinical Outcomes Assessment

Schantz K, Mangrum R, Robinson RL, Stauffer VL, Markman JD, Gewandter JS, Seçinti E

Journal of Pain Research 2025, 18:5715-5737

Published Date: 1 November 2025

Comparative Effectiveness of Optimized Versus Conventional Perioperative Care in Unilateral Biportal Endoscopy for Lumbar Degenerative Disease: A Single-Center Retrospective Study

Cui M, Tan S, Liu Y, Wang X, Chen M, Tang Y, Ding L

Journal of Pain Research 2025, 18:5701-5714

Published Date: 30 October 2025

Decoding Fibromyalgia: Genetic Insights into Gut and Immune System Interactions

Niu M, Li J, Sarafian V, Maes M

Journal of Pain Research 2025, 18:5685-5699

Published Date: 31 October 2025

A Commentary on Laser Acupuncture for the Pain of Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [Response to Letter]

Zeng DH, Yuan DN, Zhou QQ, Liu YY, Ma WB, Lan L

Journal of Pain Research 2025, 18:5681-5684

Published Date: 31 October 2025

Comparative Analysis of Paraspinal Muscle Fat Infiltration and Clinical Efficacy Following Single-Level UBD-TLIF versus MIS-TLIF: A Retrospective MRI-Based Study

Yan J, Tian M, Wu M, Yuan Z, Fan Y, Wu X, Ni H, Zhao Y, Yu S, He S

Journal of Pain Research 2025, 18:5673-5680

Published Date: 30 October 2025

Expert Opinion

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Optimal Information for Chronic Pain (OICP): Delphi Consensus on Patient Assessment and Interventional Techniques

Frutos V, Delgado D, Cuñat T, Aguilar JL, Recasens-Urbez J, Homs M, Fernandez-Bravo A, Izquierdo RM, Munoz-Ortego J, Sánchez M, Cordero-García C, Abejón D, Cayuela M

Journal of Pain Research 2025, 18:5661-5671

Published Date: 31 October 2025

Association of Health-Related Quality of Life and Pain Medication Perception Among Chronic Low Back Pain Patients at Tertiary Care Hospital: A Cross-Sectional Study

KC R, Shrestha RK, Shrestha S, Shrestha R, Bista D

Journal of Pain Research 2025, 18:5645-5659

Published Date: 30 October 2025

New Findings on Risk Factors for Postherpetic Neuralgia From 2014 to 2024: A Systematic Review and Meta-Analysis

Liang B, Wan Y, Su X, Pan X, Zhang Z, Guo X, Li M

Journal of Pain Research 2025, 18:5631-5643

Published Date: 29 October 2025

The Efficacy of Aromatherapy on Pain and Anxiety During Needle-Related Procedures in Adults: A Systematic Review and Meta-Analysis [Letter]

Wang Z, Ke S, Liu Q

Journal of Pain Research 2025, 18:5627-5629

Published Date: 28 October 2025

Pain Management for Postpartum Pain: A Narrative Review

Zhou L, Li J, Zhou Y, Liang Y, Ma Q, Yang L, Pang Y, Fang Y, Guo Y

Journal of Pain Research 2025, 18:5617-5626

Published Date: 27 October 2025

Working Memory Load-Dependent Cortical Mechanism of Distraction Analgesia in Healthy Individuals: An fNIRS Study

Du R, Lao M, Cheng M, Wang Z, Zheng Z, Tang P, Hu Y, Wu W

Journal of Pain Research 2025, 18:5599-5615

Published Date: 25 October 2025

A Review of Movement and Functional Impairments in Fibromyalgia: Implications for Targeted Treatment

Quodling N, Hoffman N, Carrick FR, Jemni M

Journal of Pain Research 2025, 18:5587-5597

Published Date: 25 October 2025

Efficacy of Acupuncture Assisted Anesthesia in Laparoscopic Cholecystectomy: A Systematic Review and Meta-Analysis

Lv H, Xu J, Bian Z, Lu Y, Li X, Jiang Y, Fang J, Liu Y

Journal of Pain Research 2025, 18:5567-5585

Published Date: 25 October 2025

Chemonucleolysis for Lumbar Disc Herniation: History and Current State of the Technology

Deer TR, Macadaeg KE, Kim KD, Copenhaver DJ, Cheng BC, Patel A, Vaccaro A, Candido KD, Gupta PB, Beall DP

Journal of Pain Research 2025, 18:5555-5565

Published Date: 25 October 2025

Acupuncture Therapy for Extremity Musculoskeletal Pain: A Clinically Focused Evidence Synthesis with Therapeutic Implications

Zhu F, Chen Y, Zhu Y, Bai Z, Yan H

Journal of Pain Research 2025, 18:5541-5554

Published Date: 24 October 2025

Concurrent Validity of the Operationalization of High-Impact Pain Construct in the Health and Retirement Study

Tamargo JA, Cruz-Almeida Y

Journal of Pain Research 2025, 18:5533-5540

Published Date: 22 October 2025

Sufentanil-Dezocine Combination in Patient-Controlled Intravenous Analgesia for Postoperative Pain After Pancreatic Cancer Surgery: A Retrospective Propensity Score-Matched Study

Huang Z, Li J, Xia Y, Li Q, Song X, Xu X, Luo Y

Journal of Pain Research 2025, 18:5523-5531

Published Date: 21 October 2025

Original Research

Pre-Clinical/Scientific

Monosodium Iodoacetate Induces Knee Osteoarthritis in Rats in a Dose- and Time-Dependent Manner

Song M, Han W, Li J, Wu G, Yu H, Yuan Q, Yu J

Journal of Pain Research 2025, 18:5507-5522

Published Date: 17 October 2025

Current Status, Trends, and Forecast Analysis of LBP Disease Burden Attributable to Occupational Ergonomic Factors in China

Yang X, Li R, Shu J, Chen H

Journal of Pain Research 2025, 18:5493-5506

Published Date: 16 October 2025

Depression as an Independent Predictor of Incident Pain: Longitudinal Evidence From CHARLS

Song W, Wang S, Cao Z, Lin J

Journal of Pain Research 2025, 18:5481-5491

Published Date: 17 October 2025

Fire Needle Therapy for Nocturnal Leg Cramps in Older Adults: A Randomized Sham-Controlled Pilot Trial Protocol

Wang X, You W, Li Y, Li B, Tian W, Sun J

Journal of Pain Research 2025, 18:5467-5480

Published Date: 17 October 2025

The Genetic Association Between Prescription Pain Medication Use and the Risk for Fibromyalgia: A Bidirectional and Multivariable Mendelian Randomization Analysis

Zhou G, Cao W, Liang S, Ye Z, Liu Z, Zou W

Journal of Pain Research 2025, 18:5455-5465

Published Date: 16 October 2025

The Clinical Efficacy and Safety of Electroacupuncture (EA) in Perioperative Rehabilitation of Rotator Cuff Repair Surgery: A Protocol for a Single-Centre, Randomized Controlled Trial

Liu K, Chen L, Fang X, Wang Y, Zhao J, Mi Y

Journal of Pain Research 2025, 18:5441-5454

Published Date: 15 October 2025

Psycho-Socio-Behavioural Substrates of Non-Cancer Chronic Pain: A Twin Study in Italian Adults

Fagnani C, Toccaceli V, Tenti M, Medda E, Ferri M, Raffaeli W

Journal of Pain Research 2025, 18:5429-5440

Published Date: 15 October 2025

Latent Profile of Pain Catastrophizing and Its Relationship to Emotional State in Patients with Ureteral Calculi: A Cross-Sectional

Yang JJ, Wang X, Wang XF, Wang LY, Shen LP

Journal of Pain Research 2025, 18:5417-5427

Published Date: 14 October 2025

Clinical Application of Muscle Energy Technique for Knee Function Recovery After Total Knee Arthroplasty

Xu L, Li J, Sheng Q, Wang G

Journal of Pain Research 2025, 18:5409-5416

Published Date: 14 October 2025

Relationship Between Perceived Stress, Resilience, Mental Health, and Pain in Women with Migraines, a Case-Control Study

Arlud S, Tong N, Xie N, Gao S, He N

Journal of Pain Research 2025, 18:5399-5408

Published Date: 13 October 2025

Age and Fibromyalgia as Moderators of the Relationships Between Pain and Loneliness: A Longitudinal Study in Patients with Chronic Pain

Wu CH, Chou WH, Yang HH, Lin T, Long YH, Yang CC, Sun WZ, Lin CP

Journal of Pain Research 2025, 18:5385-5397

Published Date: 13 October 2025

Acupuncture Modalities Differentially Modulate Pain and Joint Damage in a Rat Model of Knee Osteoarthritis

Kamau VN, Yang S, Lee G, Kim JH

Journal of Pain Research 2025, 18:5377-5384

Published Date: 13 October 2025

Long Term Effects of Acupuncture for Primary Dysmenorrhea: A Systematic Review and Meta-Analysis

Shen X, Liu S, Chen H, Wang W, Fang J, Liu Z

Journal of Pain Research 2025, 18:5359-5376

Published Date: 11 October 2025

Clinical Evidence of Acupoint Stimulation for Primary Dysmenorrhea: A Systematic Review and Updated Meta-Analysis [Letter]

Jin H, Xu W, Zhou C

Journal of Pain Research 2025, 18:5357-5358

Published Date: 11 October 2025

Comparison of Opioid Consumption During Target Controlled Infusion (TCI) Guided By Nociception Level Index (NOL) or Standard Care Undergoing Intracranial Tumor Surgery

Demirel ME, Bilgin H, Akesen S

Journal of Pain Research 2025, 18:5347-5355

Published Date: 11 October 2025

A Pharmacovigilance Study from 2004 to 2024 Utilizing the FDA Adverse Event Reporting System (FAERS) Examines Ischemic Adverse Events Linked to Triptan Use in Migraine Therapy

Xu N, Lu X

Journal of Pain Research 2025, 18:5331-5345

Published Date: 11 October 2025

Median Effective Volume of 0.25% Ropivacaine for Bilateral Transversus Thoracis Muscle Plane Block in Patients Undergoing Open Cardiac Surgery

Sun J, Liu C, Gong X, Chen R, Deng S, Zha Y, Ji S, Jin Z, Chen H

Journal of Pain Research 2025, 18:5321-5329

Published Date: 11 October 2025

Impact of Tobacco Exposure on Low Back Pain-Related Disability-Adjusted Life Years in China: Trends From 1990–2021 and Projections for the Next 15 years Using ARIMA Modeling

Song S, Feng S, Lu H, Li B

Journal of Pain Research 2025, 18:5303-5320

Published Date: 8 October 2025

Clinical Efficacy and Plasma Metabolomics Analysis of Acupuncture for Migraine Treatment

Gao L, Chen Y, Xie C, Zhang Z, Yan Q, Fu QX, Sun M, Zhao L

Journal of Pain Research 2025, 18:5283-5301

Published Date: 9 October 2025

Global Epidemiology and Burden of Migraine in Children and Adolescents from 1990 to 2021: Insights from the Global Burden of Disease Study 2021

Sun Q, Xie H, Hao L, Ding J, Hong J, Lin X, Chen Z, Lyu J, Wang N

Journal of Pain Research 2025, 18:5265-5281

Published Date: 8 October 2025

Predictive Factors of Acute Pain After Day Surgery: A Meta-Analysis

Zhang H, Gao X

Journal of Pain Research 2025, 18:5249-5263

Published Date: 8 October 2025

Effect of Intravenous Esketamine on Rebound Pain Following Single-Shot Brachial Plexus Block in Patients Undergoing Shoulder Arthroscopic Surgery: A Prospective, Randomized, Placebo-Controlled Study

Chen J, Pan Z, Zheng J

Journal of Pain Research 2025, 18:5235-5248

Published Date: 7 October 2025

High-Definition Transcranial Direct Current Stimulation Improves Pain Empathy: A Randomized, Double-Blind, and Sham-Controlled Study Based on Event-Related Potentials (ERPs)

Hu Z, Wen Y, Feng B, Wang Y, Lin Y, Shi J, Gong C, Wang Y

Journal of Pain Research 2025, 18:5223-5234

Published Date: 8 October 2025

Lipid Transporter ABCA1 in Diabetic Polyneuropathy: Potential Mediation by Circulating Metabolites

Cao Y, Pan Y, Yan Y, Yao Y, Lu S, Gei L, Jiang W, Zeng W, Chen D

Journal of Pain Research 2025, 18:5203-5222

Published Date: 6 October 2025

The Influence of Preoperative Central Sensitization on the Postoperative Prognosis of Pilon Fractures: A Retrospective Study

Liang J, Zan Q, Cao S, Wang H, Liu G, Yang W, Zhang S, Li Y, Xu J

Journal of Pain Research 2025, 18:5191-5201

Published Date: 6 October 2025

Virtual Reality Interventions for Spinal Cord Injury-Related Neuropathic Pain: A Comprehensive Scoping Review of Multidimensional Outcomes

Li Q, Du X, Zhao D, Zhang S, Liu M, Ding N, Li Y, Xing Z, Chu X, Chen L

Journal of Pain Research 2025, 18:5175-5190

Published Date: 3 October 2025

Modelling Pain Perception Using Fuzzy Cognitive Maps

Farahani H, Kovač N, Fardi H, Watson PC

Journal of Pain Research 2025, 18:5153-5174

Published Date: 3 October 2025

Bridging Pain and Motoric Cognitive Risk Syndrome: Mediating Effect of Handgrip Strength

Zhao X, Zhu Y, Han L, Zhang L, Chen J, Ding H

Journal of Pain Research 2025, 18:5141-5151

Published Date: 1 October 2025

Validation of the Arabic Version of the Fibromyalgia Survey Questionnaire

Chahine A, El Zouki CJ, Jebreen K, Ali I, Obeid S, El Tannoury BJ, Haroun R, Lahoud JC, Fekih-Romdhane F, Hallit S

Journal of Pain Research 2025, 18:5127-5140

Published Date: 30 September 2025

Effect of Exercise Interventions for Rheumatoid Arthritis: A Systematic Review and Network Meta-Analysis of Randomised Controlled Trials

Zhang Y, He Z, Yin Z, Wang J, Gao W, Jie L

Journal of Pain Research 2025, 18:5109-5126

Published Date: 30 September 2025

Advances in Electroacupuncture for Treatment of Knee Osteoarthritis: Mechanisms, Efficacy, and Future Directions

Wu X, Li S, Wu M

Journal of Pain Research 2025, 18:5083-5108

Published Date: 30 September 2025

Pericapsular Nerve Group Block for Hip Fracture Pain Management: A Narrative Review of Emergency Applications [Corrigendum]

Li YB, Zuo M, Zhu JP, Ma RL, Liao XZ

Journal of Pain Research 2025, 18:5081-5082

Published Date: 29 September 2025

Desflurane Safety Revisited: A Pharmacovigilance Study Detecting Potential Safety Signals from FAERS Data

Wei W, Chen L, Ying X

Journal of Pain Research 2025, 18:5069-5080

Published Date: 26 September 2025

Original Research

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Treatment of Painful One Level Schmorl’s Nodes Using Percutaneous Endoscopic Lumbar Discectomy: A Clinical Evaluation

Ding Z, Wang J, Guan L, Liu Y, Zhang Y, Hai Y

Journal of Pain Research 2025, 18:5057-5068

Published Date: 26 September 2025

Developing Quality Indicators for the Pharmacological Management of Chronic Non-Cancer Pain in Older Adult Inpatients: A RAND/UCLA Delphi Study

Goetschi AN, Schönenberger N, Wernli U, Meyer-Massetti C

Journal of Pain Research 2025, 18:5037-5056

Published Date: 27 September 2025

Immune Cells Mediate the Causal Pathway Linking Multisite Chronic Pain to Asthma: A Mediation Mendelian Randomization Study

Chen JH, Deng NH, Li YC, Zhu XC, Ge P, Wang XD, Jiang P, Wen ZW, Huang GT, Luo QM, Tu YY

Journal of Pain Research 2025, 18:5023-5035

Published Date: 25 September 2025

Low-Dose IL-2 Attenuates Neuropathic Pain via Treg Expansion in Rats

Zhao Y, Shen L, Huang Y

Journal of Pain Research 2025, 18:5011-5022

Published Date: 26 September 2025

Liposomal Bupivacaine for Quadratus Lumborum Block at the Lateral Supra-Arcuate Ligament in the Analgesic Effect After Laparoscopic Nephrectomy: A Single-Centre, Triple-Blind, Randomized Controlled Trial

Gong H, Wang Z, Kou G, Zheng Z, Xu L, Hang B, Peng Y, Sun Q, Jia M

Journal of Pain Research 2025, 18:4999-5009

Published Date: 26 September 2025

Review

Integrative/Acupuncture

Acupuncture in Knee Osteoarthritis: A Narrative Review of Clinical Efficacy and Neuroimmune-Endocrine Mechanisms

Jiao J, Dong B, Han Y, Zheng Q, Lin X

Journal of Pain Research 2025, 18:4989-4998

Published Date: 25 September 2025

Advances in Neuroimaging of Breast Cancer Pain: An Overview

Wei P, Liu Y, Tong J, Zhang Q, Qiu Z, Xu X

Journal of Pain Research 2025, 18:4975-4988

Published Date: 24 September 2025

The Optimal Patient Profile and Appropriate Role of Spinal Cord Stimulation (SCS) for Patients with Persistent Spinal Pain Syndrome-Type 1 (PSPS-T1) Not Suitable for Spine Surgery: A European Modified Delphi Consensus

Schulte TL, Fernández-Marín MR, Gazzeri R, Hamel O, Kallewaard JW, Poply K, Smet I, Vesper J, Van de Kelft E

Journal of Pain Research 2025, 18:4959-4973

Published Date: 25 September 2025

Reductions in Perceived Injustice are Associated with Reductions in Pain Catastrophizing in Individuals with Low Back Pain

Alpdogan NY, Coutu MF, Durand MJ, Carrière JS

Journal of Pain Research 2025, 18:4947-4957

Published Date: 23 September 2025

Effect of Acupotomy Modulation of NLRP3/Caspase-1/GSDMD Pathway on Chondrocyte Pyroptosis in Knee Osteoarthritis

Wang Y, Chen Y, Yang Y, Zhou Y, Yang Y, Zhu J

Journal of Pain Research 2025, 18:4935-4945

Published Date: 23 September 2025

An Analysis of Factors Associated with Chronic Musculoskeletal Pain, Pain Management Preferences, Coping Strategies, and Health-Related Quality of Life Among Older People: A Cross-Cultural Study

Cavlak U, Jurak I, Rusu L, Aytutuldu GK, Telebuh M, Budeanca-Babolea OB, Kısa EP, Bertic Z, Ilie EN, Grozdek Covcic G, Piele D, Begić M, Dragomir MM

Journal of Pain Research 2025, 18:4915-4934

Published Date: 23 September 2025

Association Between Preoperative Psychological Symptoms and Chronic Postsurgical Pain in Older Patients Undergoing off-Pump Coronary Artery Bypass Grafting: Mediation Analysis of Acute Pain

Cui S, Wang S, Di L, Yan L, Huang P, Wang X, Fu Z, Huang L

Journal of Pain Research 2025, 18:4901-4913

Published Date: 22 September 2025

The Short- and Long-Term Efficacy of Non-Invasive Brain Stimulation for Migraine: A Meta-Analysis

Liu M, Yong Y, Zou H, Yang L, Qian J

Journal of Pain Research 2025, 18:4883-4900

Published Date: 19 September 2025

Wrist-Ankle Acupuncture Relieves Postoperative Pain After Milligan-Morgan Hemorrhoidectomy for Mixed Hemorrhoids: A Randomized Controlled Clinical Trial

Xu M, Li W, Wang X, Gao Y, Qi L, Xu L, He Y, Dong C, Zhang J, Zhang H, Wang J

Journal of Pain Research 2025, 18:4875-4882

Published Date: 18 September 2025

A Reaffirmation to Our Call for Reform: Response to Rebuttal Letter Regarding “A Call for Reckoning and Reform in Interventional Pain Medicine and Neuromodulation Research” [Response to Letter]

D'Souza RS, Schatman ME, Hussain N

Journal of Pain Research 2025, 18:4871-4873

Published Date: 19 September 2025

Original Research

Opioids and Substance Abuse

Can Ziconotide Be Used to Replace Opioids? Exploratory Clinical Experience in 5 Patients Treated in the Pain Unit

Canovas Martínez L, Gago Diéguez N, Carrera Sieiro JL, López Díez R, García González C, Ortolá Más E, Almenara S

Journal of Pain Research 2025, 18:4859-4870

Published Date: 17 September 2025

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Changes in Pain Catastrophizing and Related Outcomes Following a Single-Session Empowered Relief Intervention Delivered by Physical Therapists in Workers with Low Back Pain: A Pilot Study

Carrière JS, Coutu MF, Darnall BD, Léonard G, Royer MP, Li MY, Bordeleau M, Durand MJ

Journal of Pain Research 2025, 18:4845-4857

Published Date: 17 September 2025

Original Research

Acute Pain and Perioperative Care

Application of Intraoperative Awake Anesthesia and Three-Dimensional Reconstruction Technique in Percutaneous Microballoon Compression for Trigeminal Neuralgia

Li X, Fan Y, Chen Z, Hui OY, Guo M, Feng G, Zhou J, Ling Y, Lin D

Journal of Pain Research 2025, 18:4833-4843

Published Date: 16 September 2025

Efficacy and Safety of Acupuncture and Acupuncture-Combined Therapies in the Treatment of Sciatica Caused by Lumbar Disc Herniation: A Network Meta-Analysis

Ni D, Tong H, Wei S, Zheng Y, Wu W, Li M, Dong Y

Journal of Pain Research 2025, 18:4809-4832

Published Date: 16 September 2025

Pericapsular Nerve Group Block for Hip Fracture Pain Management: A Narrative Review of Emergency Applications

Li YB, Zuo M, Zhu JP, Ma RL, Liao XZ

Journal of Pain Research 2025, 18:4801-4807

Published Date: 15 September 2025

Single- versus Multiple-Injection Intertransverse Process Block for VATS: A Randomized Trial on Dermatomal Sensory Blockade

Supphapipat K, Samerchua A, Leurcharusmee P, Lapisatepun P, Pipanmekaporn T, Konkarn N, Prapussarakul K, Jinadech T, Wanvoharn M

Journal of Pain Research 2025, 18:4791-4800

Published Date: 15 September 2025

Interpreting the Evidence for Laser Acupuncture in Knee Osteoarthritis Management: A Call for Methodological Rigor and Nuance [Letter]

Zhao FY, Fu QQ, Ho YS

Journal of Pain Research 2025, 18:4787-4790

Published Date: 14 September 2025

Erector Spinae Plane versus Pectoralis Nerve Block for Mastectomy in Cancer Patients: A Retrospective, Multicenter Cohort Study

Yap EN, Wei J, Darling C, Linehan E, Behrends M, Ng KP

Journal of Pain Research 2025, 18:4775-4785

Published Date: 16 September 2025

Efficacy and Safety of Fu’s Subcutaneous Needling in the Treatment of Cervical Spondylosis: A Systematic Review and Meta-Analysis Based on Randomized Controlled Trials

Shen Y, Chen J, Tang S, Xiao B

Journal of Pain Research 2025, 18:4759-4774

Published Date: 12 September 2025

Rebuttal Letter to the Editor: Defending Evidence-Based Practices in Interventional Pain Medicine [Letter]

Kalia H, Suvar T, Chung M, Gulati A

Journal of Pain Research 2025, 18:4755-4757

Published Date: 12 September 2025

Acupuncture at Myofascial Trigger Points Versus Conventional Acupuncture for Knee Osteoarthritis: A Protocol for a Randomized Controlled Trial

Zhang C, Xue H, Xu J, Liu A, Gao K, Zhang L

Journal of Pain Research 2025, 18:4743-4753

Published Date: 11 September 2025

Original Research

Acute Pain and Perioperative Care

Preferential Flow Patterns of Injectate in Epidural and Inadvertent Subdural Anesthesia: Exploring the Hemodynamic Stability of High-Level Epidural, Subdural and Combined Epidural-Subdural Blocks in Relation to ASA Class

Kang SY, Kim HS, Kang H

Journal of Pain Research 2025, 18:4727-4741

Published Date: 10 September 2025

Comprehensive Mechanisms and Non-Invasive Treatment for Complex Regional Pain Syndrome: A Narrative Review

Doan HN, Chang MC

Journal of Pain Research 2025, 18:4699-4726

Published Date: 11 September 2025

Review

Pain Education and Early Career Investigators

Circadian Rhythms and Pain: A Narrative Review on Clock Genes and Circadian-Based Interventions

Huang ZQ, Li XQ, Wang YD, Li JY, Tian YH, Liu YM, Si JQ

Journal of Pain Research 2025, 18:4687-4698

Published Date: 9 September 2025

Tuina Combined with Other Treatment Methods for Scapulohumeral Periarthritis (Frozen Shoulder): Bayesian Network Meta-Analysis

Wang S, Zhang F, Chen J, Fu G

Journal of Pain Research 2025, 18:4673-4686

Published Date: 8 September 2025

Acupuncture Therapy for Sciatica: An Overview of Systematic Reviews and Meta-Analysis

Zhang J, Guo Z, Wang L, Lin R, Xiao B, Liu W, Xu N, Cui S

Journal of Pain Research 2025, 18:4651-4671

Published Date: 7 September 2025

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Comparison of Mobile Health-Based Exercise vs Traditional Exercise for Chronic Neck Pain: A Systematic Review and Meta-Analysis

He X, Zhou H, Jiang YS, Liu DC, Qi F, Wang Z

Journal of Pain Research 2025, 18:4639-4649

Published Date: 7 September 2025

Pain Medicine Needs an Open-Access Data Revolution

Durbhakula S, Schatman ME, Byram BC, Bruehl S

Journal of Pain Research 2025, 18:4635-4637

Published Date: 7 September 2025

Efficacy of Myofascial Trigger Point Dry Needling in Treatment of Primary Dysmenorrhea: A Study Protocol for a Three-Arm Randomized Controlled Trial

Sun Y, Yang L, Zhu L, Zhang S, Cheng W, Lin L, Li W, Li M, Zhao X, Guo J, Hua Z

Journal of Pain Research 2025, 18:4623-4633

Published Date: 5 September 2025

Knowledge, Attitude, and Practice Toward Chronic Pain in Older Adults Among Health Sciences Students: A Cross-Sectional Study

Shi Z, Chen YB

Journal of Pain Research 2025, 18:4611-4622

Published Date: 5 September 2025

Pain, Progress, and Price: A Review of Conservative and Complementary Treatments for Low Back Pain

Putra BH, Sinuraya RK, Suwantika AA

Journal of Pain Research 2025, 18:4599-4610

Published Date: 5 September 2025

Pain Phenotyping Indicators in Older Adults with Chronic Low Back Pain: A Secondary Analysis of a Randomized Controlled Trial

Hamilton KR, Lukkahatai N, Chen W, Wu H, Kawi J, Johnson CM, Christo PJ, Campbell CM

Journal of Pain Research 2025, 18:4589-4598

Published Date: 5 September 2025

A Swiss Cross-Sectional Study on Patients’ Perspectives on Chronic Pain Management, Analgesic Treatment, and Genetic Susceptibility

Bollinger A, Stäuble CK, Urdieux IO, Meyer zu Schwabedissen HE, Allemann SS

Journal of Pain Research 2025, 18:4575-4587

Published Date: 5 September 2025

Exploratory Analysis of Respiratory Variability in Relation to Disease Impact, Affective Symptoms, and Pain Sensitivity in Fibromyalgia

van den Bosch OFC, van Lennep JPA, Alvarez-Jimenez R, van Middendorp H, Evers AWM, Steegers MAH, Schober P, Loer SA

Journal of Pain Research 2025, 18:4565-4574

Published Date: 6 September 2025

Fractional Amplitude of Low-Frequency Fluctuations and Regional Homogeneity Analyses Revealed Altered Local Spontaneous Neural Activities in Ankylosing Spondylitis

Lin C, Xie Y, Liu D, Liu B, Gu J, Wang X, Qin J

Journal of Pain Research 2025, 18:4551-4563

Published Date: 2 September 2025

Low-Dose Ropivacaine-Fentanyl Spinal Anesthesia Combined with Carbetocin for Cesarean Section: A Randomized Double-Blind Non-Inferiority Trial

Li M, Xie G, Chu L, Lu Y, Xu T, Li Y

Journal of Pain Research 2025, 18:4539-4550

Published Date: 2 September 2025

Obstructive Sleep Apnea and Postoperative Hyperalgesia in Bariatric Surgery: A Prospective Observational Cohort Study

Zhong Z, Lu X, Zhang Q, Zhang Y

Journal of Pain Research 2025, 18:4527-4538

Published Date: 2 September 2025

Paravertebral Block versus Erector Spinae Plane Block for Postoperative Analgesia and Recovery: A Systematic Review and Meta-Analysis

Ren D, Wang D, Zhang W, Lei L, He X, Yue H

Journal of Pain Research 2025, 18:4509-4526

Published Date: 2 September 2025

Temporal Summation of Repetitive Mechanical Stimulation in Patients with Painful Temporomandibular Joints and Healthy Controls

Xi X, Jin R, Yu L, Shi J, Wang C, Wang K, Zhang J, Chen Y, Zhou W

Journal of Pain Research 2025, 18:4497-4507

Published Date: 2 September 2025

Identification of Common Genes for Neuropathic Pain and Parkinson’s Disease Based on Bioinformatics Analysis and Their Potential Value in the Diagnosis of Neuropathic Pain

Xue S, Deng S

Journal of Pain Research 2025, 18:4483-4495

Published Date: 1 September 2025

Efficacy and Safety of Magnetic Peripheral Nerve Stimulation for Treatment of Neuropathic Pain; One Year Follow Up of Long-Term Outcomes

Kapural L, Patel J, Rosenberg JC, Li S, Amirdelfan K, Bedder M

Journal of Pain Research 2025, 18:4471-4481

Published Date: 30 August 2025

Longitudinal Changes in Sensory Processing and Clinical Outcomes During Spinal Cord and Dorsal Root Ganglion Stimulation to Treat Chronic Pain: A Pilot Study

Rogers ER, Sankarasubramanian V, Kyi WHT, Mirzakhalili E, Anaya CJ, Loechli J, Harte SE, Patil PG, Chiravuri S, Lempka SF

Journal of Pain Research 2025, 18:4455-4470

Published Date: 29 August 2025

Quality Evaluation of Literature Reports on Clinical Randomized Controlled Trials of Acupuncture Treatment for Stable Angina Pectoris

Cai B, Su Z, Wang H, Li M, Gai X, Wei Y, Li M

Journal of Pain Research 2025, 18:4443-4454

Published Date: 28 August 2025

Safety and Efficacy of Interspinous Fixation Device via Lateral Transverse Approach in Patients with Lumbar Spinal Stenosis: A Single Center, Retrospective, Observational Study

Soto E, Esposito MF

Journal of Pain Research 2025, 18:4431-4441

Published Date: 27 August 2025

The Analgesic Effect of NLRP3 Inflammasome in the Relief of Inflammatory Pain by Electroacupuncture: A Systematic Review and Meta-Analysis of Animal Studies

Su R, Wang Z, Zhang G, Tao Y, Zhu H, Chen H, Li J, Sun Z

Journal of Pain Research 2025, 18:4413-4430

Published Date: 27 August 2025

Oxymatrine Alleviates Central Post-Stroke Pain in Rats by Reducing the Inflammatory Response

Li HL, Tan XP, Wang XD, Guo RT, Wang JL

Journal of Pain Research 2025, 18:4401-4412

Published Date: 27 August 2025

Acupuncture for Rapid Pain Relief and Restoration of Motor Function in Acute Lateral Ankle Sprains: A Randomized Controlled Trial Protocol Based on Infrared Thermography

Wen W, Jin Y, Deng Y, Zhao S, Tang X, Li W, Song L, Lv Z, Guo T, Liang F

Journal of Pain Research 2025, 18:4387-4399

Published Date: 27 August 2025

A Pluripotent Progression of the Gate Control System Theory of Pain – Modeling Ascending & Descending Pain Pathways as a Lotka-Volterra Coupled Control & Feedback Loop

Fink W, Raffa RB

Journal of Pain Research 2025, 18:4373-4385

Published Date: 26 August 2025

Whole-Workflow Robotic-Assisted Percutaneous Endoscopic Lumbar Discectomy via a Two-Step Access Method: Technical Report and Preliminary Results

Zheng W, Wu J, Xia W, Zuo R, Chang X, Yin H, Li C, Zhang C

Journal of Pain Research 2025, 18:4361-4371

Published Date: 25 August 2025

Esketamine as an Epidural Adjuvant for Postoperative Analgesia in Gynecological Malignancy Surgery: A Randomized Trial

Luo H, Yang Y, He Z, Pan C, Wu X, Cao S, Zhang J

Journal of Pain Research 2025, 18:4349-4359

Published Date: 23 August 2025

Real-World Effectiveness of a Novel AI-Software Dependent Neuromodulation (ASDN) with Remote Monitoring Capability Field Stimulation Device for Chronic Pain: A 24-Month Analysis of Over 2000 Patients

Green M, Cabble A, Bailey M, Kappell ML, Billet B, Kim CW, Singh JR, Suthar M, Kalia H, Kappell S, Chakravarthy K

Journal of Pain Research 2025, 18:4337-4348

Published Date: 23 August 2025

Clinical Evidence of Acupoint Stimulation for Primary Dysmenorrhea: A Systematic Review and Updated Meta-Analysis

Wang Y, Liu L, Wu X, Wu Y, Qin R, Wang M, Zhou B, Sun J, Song Y, Zhang M, Li M, Yu L

Journal of Pain Research 2025, 18:4307-4336

Published Date: 24 August 2025

Different Acupuncture Treatments for Myofascial Pain Syndrome in Neck or Shoulder: A Network Meta-Analysis Based on Randomized Controlled Trials

Wang T, Gu Y, Li Y, Chen J, Zeng L

Journal of Pain Research 2025, 18:4289-4305

Published Date: 24 August 2025

Neuraxial Homeostasis – Optimizing Neuraxial Labor Analgesia

Guo J, Cheng Y, Yi M

Journal of Pain Research 2025, 18:4285-4288

Published Date: 22 August 2025

Neuralgia Inducing Cavitational Osteonecrosis of the Jaw: Scientific Controversy or pseudoscience?

Keith DA

Journal of Pain Research 2025, 18:4275-4284

Published Date: 24 August 2025

The Role of Lifestyle Behaviors in Shaping the Relationship Between Chronic Pain and Epigenetic Age Acceleration: Evidence From NHANES 1998 to 2002

Ke Y, Wu C, Cheng Z, Liang M

Journal of Pain Research 2025, 18:4263-4273

Published Date: 22 August 2025

A Systematic Review on Health Economic Evaluations of Telerehabilitation for Chronic Spinal Pain

Cai M, Ku X, Xu L, Liu F

Journal of Pain Research 2025, 18:4251-4262

Published Date: 21 August 2025

Efficacy and Safety of the Bushen Quhan Zhiwang Decoction to Achieve Clinical Deep Remission in Rheumatoid Arthritis: Protocol for a Double-Blind, Randomized, Placebo-Controlled Trial

Liu L, Wang J, Chen Y, Fang Y, Wang Z, Liu X, Hong L, Tao Q, Xu Y

Journal of Pain Research 2025, 18:4237-4249

Published Date: 21 August 2025

Guidelines From the American Society of Pain and Neuroscience for Using Artificial Intelligence in Interventional Spine and Nerve Treatment

Massey C, Latif U, Deer TR, Kalia H, Guirguis M, Bicket MC, Khatri N, Tolba R, Chakravarthy K, Budwany R, Lee DW, Patel AA, Moreira AM, Jimenez DA, Patel RG, Cowan I, Christiansen S, Wilson D, Chapman KB, Vu C, Manzi S, Nashi S, Waheed M, Shah A, Nasseri M, Buchanan P, Azeem N, Petersen EA, Schatman ME, Abd-Elsayed A, Sayed D, Diwan S

Journal of Pain Research 2025, 18:4211-4235

Published Date: 20 August 2025

Thoracic Epidural Block versus Conscious Sedation with Intercostal Nerve Block for Thermal Ablation of Lung Tumors: A Comparative Study

Lin CY, Chung TJ, Lai WW, Tseng YL, Yen YT, Liu YS, Chang CC, Hsiao HT

Journal of Pain Research 2025, 18:4201-4210

Published Date: 20 August 2025

Social Connection and Chronic Pain: A Cohort Study to Explore the Association of Social Isolation and Loneliness with Chronic Pain Among Older Adults in China

Han X, Qiao Y, Tan J, Luo Z, Nicholas S, Maitland E, Han L, Xu Z, Wang J

Journal of Pain Research 2025, 18:4187-4199

Published Date: 20 August 2025

Platelet-Rich Plasma-Induced Analgesia in Peripheral Nerve Repair: Mechanisms, Cautions, and Clinical Promise [Response to Letter]

Kuffler DP, Reyes O, Sosa IJ, Micheo WF, Santiago-Figueroa JM, Foy CA

Journal of Pain Research 2025, 18:4185-4186

Published Date: 21 August 2025

Postoperative Rehabilitation for Pain and Functional Recovery Following Anterior Cervical Discectomy and Fusion: A Narrative Review

Yang S, Yi YG, Kim Y, Jang DS, Chang MC

Journal of Pain Research 2025, 18:4173-4183

Published Date: 20 August 2025

Effects of Tissue-Bone Homeostasis Manipulation at Different Time Points on Pain and Brain Mechanisms in Patients with Knee Osteoarthritis Based on Circadian Rhythm: Study Protocol for a Randomized Controlled Trial

Ma H, Ding Y, Yang K, Zhang Z, Xu H, Feng W, Jiang L

Journal of Pain Research 2025, 18:4161-4172

Published Date: 19 August 2025

Factors Influencing Chronic Pain After Hysterectomy for Uterine Fibroids: Development and Validation of a Nomogram Prediction Model

Liang H, Luo Y, Chen X, Hou T

Journal of Pain Research 2025, 18:4151-4160

Published Date: 18 August 2025

Context-Dependent Roles of Four Classes of Bioactive Lipids in Neuroglia-Mediated Regulation of Neuroinflammation

Sun S, Hu S, Wang Y, Sun M, Zhao L

Journal of Pain Research 2025, 18:4139-4149

Published Date: 18 August 2025

Acupotomy for Military Training-Induced Lumbar Radiculopathy with Sciatica: Protocol of a Randomized Controlled Trial

Hong K, Gao J, Hu L, Long X, Wu X, Wen B

Journal of Pain Research 2025, 18:4123-4138

Published Date: 16 August 2025

A Study of the Safety of Low Temperature Plasma Radiofrequency Ablation on Rat Sciatic Nerve

Zhang K, Xu Y, Yin T, Ji F, Xu H

Journal of Pain Research 2025, 18:4109-4121

Published Date: 14 August 2025

Platelet-Rich Plasma-Induced Analgesia in Peripheral Nerve Repair: Mechanisms, Cautions, and Clinical Promise [Letter]

Shi Z, Shan L, Yang C

Journal of Pain Research 2025, 18:4107-4108

Published Date: 14 August 2025

Effectiveness of Electromagnetic Field Therapy in Mechanical Low Back Pain: A Randomized Controlled Trial [Letter]

Mishra B, Aggarwal A, Srivastava A

Journal of Pain Research 2025, 18:4105-4106

Published Date: 14 August 2025

Borneol’s Pre-Clinical Analgesic Efficacy: Mediated by Receptor and Immune Mechanisms

Zhou Y, Mei X, Wang C

Journal of Pain Research 2025, 18:4085-4104

Published Date: 13 August 2025

Programmed Intermittent Bolus versus Continuous Infusion for Regional Analgesia Following Thoracoscopic Surgery: A Systematic Review and Meta-Analysis

Ren D, Liu Z, Gao Y, Xie N, Lu Y, Ge L

Journal of Pain Research 2025, 18:4073-4083

Published Date: 13 August 2025

The Efficacy of Aromatherapy on Pain and Anxiety During Needle-Related Procedures in Adults: A Systematic Review and Meta-Analysis

Sun C, Fei C, Lin R, Qiu X, Wang W, Jiang X, Sun F, Wang Y, Tang L

Journal of Pain Research 2025, 18:4053-4072

Published Date: 13 August 2025

Exploring Pain Clinical Specialists’ Perspectives on Opioid Optimization for Chronic Non-Malignant Pain in England

Alenezi A, Paudyal V, Yahyouche A

Journal of Pain Research 2025, 18:4037-4051

Published Date: 13 August 2025

Ultrasonic Bone Scalpel vs Turbine Drill in Mandibular Third Molar Extraction: Impact on Postoperative Pain and Inflammation

Wang G, Wang H, Xu J, Zhang X

Journal of Pain Research 2025, 18:4029-4036

Published Date: 12 August 2025

Efficacy of Dexmedetomidine as an Adjuvant to Ropivacaine for Intercostal Nerve Block in Elderly Patients Undergoing Video-Assisted Thoracoscopic Esophagectomy: A randomized Double-Blinded Trial

Li F, Gao P, Zhang X

Journal of Pain Research 2025, 18:4019-4027

Published Date: 12 August 2025

Corticospinal Excitability in Bilateral M1 Hand Areas: Association with Neuropathic Pain After Spinal Cord Injury

Liu X, Dai C, Gao M, Lin X, Xi X, Wu X, Cheng G, Han T, Li Q, Lu Y, Sun X, Yuan H

Journal of Pain Research 2025, 18:4003-4018

Published Date: 11 August 2025

Postmarketing Research for Opioid Abuse-Deterrent Formulations: A Narrative Review

Webster L, Gudin J, Green JL, Argoff CE

Journal of Pain Research 2025, 18:3987-4001

Published Date: 9 August 2025

Negative Correlation Between Fractional Anisotropy on Diffusion Tensor Imaging and Neck Disability Index in Cervical Spondylotic Radiculopathy After Percutaneous Cervical Nucleoplasty: A Cross-Sectional Study

Fan N, Li T, Lu X, Ma X, Yang L, Du P, Zang L, Yuan S

Journal of Pain Research 2025, 18:3977-3986

Published Date: 8 August 2025

Original Research

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Clinical Predictors of Pain Relief with 60-Day Peripheral Nerve Stimulation: A Multicenter Observational Study

Odonkor CA, Oghenesume O, Hirani S, Bohacek S, Gutierrez DE, Sekhar R, McCormick ZL, Poree L, Abd-Elsayed A

Journal of Pain Research 2025, 18:3963-3976

Published Date: 8 August 2025

Comparative Effectiveness of Different Frequencies of Spinal Cord Stimulation for the Treatment of Patients with Failed Back Surgery Syndrome: Systematic Review and Network Meta-Analysis

Qin YY, Zhang CP, Tang SS, Wu JP, Zhu LX, Li YH, Xu F

Journal of Pain Research 2025, 18:3943-3961

Published Date: 9 August 2025

Dorsal Root Ganglion Pulsed Radiofrequency with Scar Radiofrequency Ablation Combined for Chronic Postoperative Abdominal Pain: A Retrospective Study

Gu R, Huang Y, Li Y, Zhu T, Ma C, Tao G

Journal of Pain Research 2025, 18:3933-3942

Published Date: 7 August 2025

Efficacy of Cognitive Behavioral Therapy for Kinesiophobia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Zhu S, Xu Y, Wang L, Chen J, Luo A

Journal of Pain Research 2025, 18:3919-3932

Published Date: 6 August 2025

Activation of TLR4/CCL2 in Intact Neurons Drives Radicular Injury-Induced Global Nerve Trunk Hypersensitivity in Radiculopathy Preclinical Models

Tong SH, Zhou J, Ye F, Ding P, Mei JL, Liao P, Lu YF, Zong Y, Gao CA, Zhang SY, Gao JJ, Liu DL, Huang YG

Journal of Pain Research 2025, 18:3903-3918

Published Date: 4 August 2025

Original Research

Surgical Approaches to Pain

Ultrasonic Bone Scalpel in Anterior Cervical Discectomy and Fusion Enhances Outcomes and Foraminal Decompression in Cervical Radiculopathy: A Retrospective Cohort Study

Peng Z, Xiong Y, Jia Y, Li J, Liu Z, Wang G

Journal of Pain Research 2025, 18:3891-3902

Published Date: 4 August 2025

Early Musculoskeletal Pain Management in the General Practitioner’s Office & E-Referral: A Multidisciplinary Expert Opinion

Gervasoni F, Farì G, Franco M, Liguori S, Maschietto L, Michieli R, Raimondo E, Scaturro D, Ventriglia G, Magni A

Journal of Pain Research 2025, 18:3879-3889

Published Date: 12 August 2025

GPER Enhances Chronic Burn Pain via PKC-Mediated Mu-Opioid Receptor Phosphorylation in the Rostral Ventromedial Medulla

Zhu X, Zhang Y, Zhang Q, Zhang Z

Journal of Pain Research 2025, 18:3859-3878

Published Date: 2 August 2025

Single-Injection Adductor Canal Block Enhances Early Mobilization with Comparable Analgesia to Continuous Infusion in Unicompartmental Knee Arthroplasty: A Retrospective Cohort Study

Lan F, Chong Y, Liu F, Wang T

Journal of Pain Research 2025, 18:3851-3858

Published Date: 1 August 2025

Pericapsular Nerve Group Block in Combination with Lateral Femoral Cutaneous Nerve and Sacral Plexus Blocks for Hip Fracture: A Case Series

Liu X, Li L, Liu J, Dong Y

Journal of Pain Research 2025, 18:3843-3850

Published Date: 1 August 2025

Laser Acupuncture for the Pain of Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Zeng DH, Yuan DN, Zhou QQ, Liu YY, Ma WB, Lan L

Journal of Pain Research 2025, 18:3833-3841

Published Date: 1 August 2025

Large-Channel Interlaminar Endoscopic Discectomy for Highly Migrated Lumbar Disc Herniation: Effectiveness and Safety

Zheng S, Zhao Q, Hu Z, Li H, Wang B, Zhu Z, Qiu Y, Sun X

Journal of Pain Research 2025, 18:3821-3832

Published Date: 1 August 2025

Response to Letter

Integrative/Acupuncture

Analysis of Acupoint Selection and Combinations in Acupuncture Treatment of Trigeminal Neuralgia: A Protocol for Data Mining [Response to Letter]

He Y, Tang J, Xu Y

Journal of Pain Research 2025, 18:3819-3820

Published Date: 31 July 2025

Causal Effects of Inflammatory Arthritis Subtypes on Fibromyalgia: A Comprehensive Mendelian Randomization Study

Wang F, Jiang D, Zhang Z, Hu Z, Liang Y

Journal of Pain Research 2025, 18:3805-3817

Published Date: 31 July 2025

Immediate Analgesic Efficacy of Acupuncture in Acute Postoperative Pain Following Internal Fixation of Intertrochanteric Femoral Fractures: Protocol for a Randomized Controlled Trial

Wang H, Wang T, Tang X, Tang X, Li C, Deng Y, Li Q, Liang F, Liao J, Guo T

Journal of Pain Research 2025, 18:3793-3803

Published Date: 31 July 2025

Associations Between Lifetime Histories of Iron Deficiency, Anxiety, Depression and Multiple Pain Conditions: An Observational Study Using a Large-Scale National Database

Champion D, Bui M, Aouad P, Teng A, Walters AS, Karroum EG, Tan AC, Yang Z, Joyce E, Jaaniste T

Journal of Pain Research 2025, 18:3781-3792

Published Date: 30 July 2025

Effect of Acupuncture on Functional Connectivity of the Limbic Network in Patients with Knee Osteoarthritis: A Resting State Functional Magnetic Resonance Imaging Study

Wu N, Lou XS, Chang YN, Li JY, Zhang ZH, Hu JH, Fan Y, Feng XD, Yin S

Journal of Pain Research 2025, 18:3765-3780

Published Date: 31 July 2025

Reviewing the Advances in Remote Therapeutic and Physiological Monitoring and Applicability for Chronic Pain Management

Ra OH, Sou BS, Streid J, Davis D, Solano Romero JP, King Jr R, Lurie JM, Vu K, Oh DJ, Robinson CL, Yong RJ, Lee KW, Issa M

Journal of Pain Research 2025, 18:3757-3764

Published Date: 30 July 2025

Core Outcome Sets for Pain Disorders: A Systematic Review of Research and Reporting Quality

Cui Y, Li B, Jiang S, Li Y, Wang S

Journal of Pain Research 2025, 18:3745-3756

Published Date: 28 July 2025

Letter

Integrative/Acupuncture

Analysis of Acupoint Selection and Combinations in Acupuncture Treatment of Trigeminal Neuralgia: A Protocol for Data Mining [Letter]

Jiang Y, Xia Q, Liu Q

Journal of Pain Research 2025, 18:3743-3744

Published Date: 25 July 2025

Addressing Pain in Oral Mucositis: Narrative Review of Current Practices and Emerging Treatments

Villa JF, Strang A, Owolabi A, Ramirez MF

Journal of Pain Research 2025, 18:3723-3741

Published Date: 23 July 2025

Does Thunder-Fire Moxibustion Really Augment Therapeutic Efficacy in Knee Osteoarthritis? Methodological Critique of A Recent Pairwise Meta-Analysis [Letter]

Zhao FY, Fu QQ, Ho YS

Journal of Pain Research 2025, 18:3717-3722

Published Date: 23 July 2025

Minimal Clinically Important Difference in Patients with Acute Neck Pain Undergoing Conservative Treatment with Korean Medicine

Kim JS, Kim E, Shin S, Ha IH, Lee YJ

Journal of Pain Research 2025, 18:3709-3716

Published Date: 23 July 2025

Pragmatic Randomized Controlled Trial of Pharmacopuncture Therapy for Cervical Disc Herniation: A Pilot Study

Lee SW, Ahn YJ, Kim S, Lee Y, Cho HW, Hong Y, Nam D, Park YC, Kim EJ, Lee YJ, Ha IH

Journal of Pain Research 2025, 18:3689-3707

Published Date: 23 July 2025

Causal Relationship Between Migraine and Postpartum Depression: A Two-Sample Bidirectional Mendelian Randomization Study

Zhou XJ, Chen R, Niu YM

Journal of Pain Research 2025, 18:3675-3687

Published Date: 22 July 2025

Review

Integrative/Acupuncture

Efficacy of Different Acupuncture Therapies for Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Network Meta-Analysis

Qin P, Cao X, Ni H, Yang L, Tong Y, Dang M, Xu J

Journal of Pain Research 2025, 18:3653-3673

Published Date: 17 July 2025

Knee Pain Expansion in Early Osteoarthritis: Findings from Iwaki Cohort Study

Tomita R, Sasaki E, Sato E, Sakamoto Y, Kimura Y, Tsushima T, Tsuda E, Ishida M, Ishibashi Y

Journal of Pain Research 2025, 18:3643-3652

Published Date: 16 July 2025

Clinical Effectiveness of Perineural Liposomal Bupivacaine is Not Superior to Bupivacaine Hydrochloride for the Prevention of Postoperative Pain in Orthopedic Surgery: A Systematic Review and Meta-Analysis with Trial Sequential Analysis

Wan M, Liang X, Meng J, Wu H, Xi C

Journal of Pain Research 2025, 18:3627-3642

Published Date: 16 July 2025

Analyzing Pain Patterns in Stroke Survivors in Outpatient Clinics: A Retrospective, Cross-Sectional, Observational Study

Dishman D, Gonzalez C, Thomas TS, Indupuru HK, Kim S, Green C, Sharrief A, Savitz SI

Journal of Pain Research 2025, 18:3609-3626

Published Date: 16 July 2025

Effects of Electroacupuncture and Mecobalamin for Utidelon-Induced Peripheral Neuropathy in Breast Cancer Patients: A Randomized Controlled Clinical Trial

Lu C, Shen Q, Deng D, Zhang Y, Wang P, Shao X, Deng Y, Bao W, Chen W, Li G

Journal of Pain Research 2025, 18:3593-3608

Published Date: 16 July 2025

Electroacupuncture and Parecoxib Reduce Inflammatory Injury in a Primary Dysmenorrhea Rat Model: Investigating the Role of the COX-2/NF-κB/NLRP3 Pathway

Xue X, Wang S, Li J, Yuan H, Pan S, Liu X, Yue Z, Liu Y

Journal of Pain Research 2025, 18:3573-3592

Published Date: 15 July 2025

Multisite Chronic Pain and the Risk of Breast Cancer and Its Subtypes: A Mendelian Randomization Study [Letter]

Meng R

Journal of Pain Research 2025, 18:3571-3572

Published Date: 14 July 2025

A Call for Reckoning and Reform in Interventional Pain Medicine and Neuromodulation Research

D’Souza RS, Schatman ME, Hussain N

Journal of Pain Research 2025, 18:3565-3569

Published Date: 13 July 2025

The Efficacy of CT-Guided Pulsed Radiofrequency of the Dorsal Root Ganglion Combined with Methylene Blue Sympathetic Injection on Herpes-Zoster Neuralgia: A Retrospective Study

Chen J, Deng J, Wang R, Ma L

Journal of Pain Research 2025, 18:3551-3564

Published Date: 11 July 2025

Comparison of the Effects of 20 W and 40 W Electrocautery Power on Postoperative Pain Following Internal Thoracic Artery Harvesting in Coronary Bypass Surgery

Ersoy GG

Journal of Pain Research 2025, 18:3543-3550

Published Date: 12 July 2025

Exploration of the Application Rules and Clinical Significance of Acupoints in Acupuncture Treatment of Migraine Based on Data Mining [Response to Letter]

He Y, Wu Y, Li X

Journal of Pain Research 2025, 18:3541-3542

Published Date: 10 July 2025

Minimally Invasive Lumbar Decompression (MILD) in Patients with Lumbar Spinal Stenosis: A Systematic Review of Randomized and Prospective Trials

Orhurhu V, Brancolini S, Zheng D, Snyder S, Jevotovsky DS, Chopra H, Sahni S, Li N, D’Souza RS, Evankovich M, Lynch B, Farrell ME, Alter BJ, Emerick T

Journal of Pain Research 2025, 18:3527-3540

Published Date: 11 July 2025

Pocket Fills for Intrathecal Pump Delivery Systems: A Narrative Review

Banks DW, Jevotovsky DS, Oehlermarx W, Broachwala M, Gulati A, Chakravarthy K

Journal of Pain Research 2025, 18:3519-3526

Published Date: 10 July 2025

Analysis and 15-Year Projections of the Global Burden of Tension-Type Headache by Sex from 1990 to 2021: A Systematic Review of GBD 2021 Data

Xu H, Qin X, Zhao G, Feng Z, You S

Journal of Pain Research 2025, 18:3505-3517

Published Date: 10 July 2025

Association Between Opioid Use and Emergency Department Visits for Spine-Related Disorders

Okeke C, Okoye G, Thornton JD

Journal of Pain Research 2025, 18:3493-3504

Published Date: 10 July 2025

Efficacy and Safety of Bushen Jiedu Tongluo Decoction in Active Rheumatoid Arthritis: Study Protocol for a Multi-Center, Randomized, Double-Blind, Controlled Trial

He Y, Shen J, Wu H, Chen L, Zhou Q, Wang Q, Guo Y, Wu F, Pan X

Journal of Pain Research 2025, 18:3477-3491

Published Date: 10 July 2025

Exploring Causality Between Bone Mineral Density and Cervical Spondylosis: Bidirectional and Multivariable Mendelian Randomization Study

Mao W, Wu L

Journal of Pain Research 2025, 18:3463-3476

Published Date: 9 July 2025

Chronic Abdominal Discomfort Syndrome (CADS): A Narrative Review of Treatment Strategies

Gupta M, Patil AS, Staats P, Schatman ME, Kalia H, Sayed D, Soin A, Baranidharan G, Kapural L, Chitneni A, Verrills P, Diwan S, Abd-Elsayed AA, Deer TR

Journal of Pain Research 2025, 18:3451-3462

Published Date: 8 July 2025

Variability in Pain Traits Among Young Individuals with High and Low Pain Sensitivity

Zhi Y, Mao Z, Zhang M, Kong Y

Journal of Pain Research 2025, 18:3439-3450

Published Date: 8 July 2025

A Bidirectional Mendelian Randomization Study of Causal Relationships Between Migraine and White-Matter Structural Connectivity

Tong D, Zhang X, Xiao Z, Taothong S, Teeravarunyou P, Wu W, Wu S, Chen N, Tao S, Zhou J, Song Q, Liang F, Li Z

Journal of Pain Research 2025, 18:3429-3438

Published Date: 9 July 2025

A Novel Presurgical Risk Prediction Model for Chronic Post-Surgical Pain in Adults Undergoing Surgical Procedures: Development and Internal Validation of the P4-Prevoque Questionnaire [PERISCOPE Trial]

Wildemeersch D, Wauters E, Roelant E, Verhaegen I, De Clerck GR, Dankerlui R, Saldien V, Hans GH

Journal of Pain Research 2025, 18:3415-3428

Published Date: 5 July 2025

Identifying Diagnostic Biomarkers for Electroacupuncture Treatment of Rheumatoid Arthritis Using Bioinformatic Analysis and Machine Learning Algorithms

Sun Y, Dong G, Gao H, Yao Y, Yang H

Journal of Pain Research 2025, 18:3403-3414

Published Date: 5 July 2025

The Causal Effects Between Circulating Inflammatory Proteins and Osteoarthritis: A Mendelian Randomization and Transcriptomic Analysis

Lin S, Wu C, Pan Y

Journal of Pain Research 2025, 18:3383-3402

Published Date: 4 July 2025

Analysis of Acupoint Selection and Combinations in Acupuncture Treatment of Trigeminal Neuralgia: A Protocol for Data Mining

He Y, Li L, Zhou M, Xu Y, Tang J, Wu Y, Liu M, Xing B, Li X, Wang X

Journal of Pain Research 2025, 18:3373-3381

Published Date: 3 July 2025

A Commentary on Efficacy of Acupuncture and Pharmacotherapy for Migraine Prophylaxis: A Systematic Review and Meta-Analysis [Letter]

Fu L, Li Z, Ma R

Journal of Pain Research 2025, 18:3371-3372

Published Date: 3 July 2025

Combined Functional and Structural Imaging of White Matter Reveals Brain Connectivity Alterations in Fibromyalgia Patients

Gao Z, Xie X, Liu F, Xu T, Zhang N, Zhang X, Li Y, Kong Y, Lv D, Wu T

Journal of Pain Research 2025, 18:3361-3370

Published Date: 3 July 2025

Exploration of the Application Rules and Clinical Significance of Acupoints in Acupuncture Treatment of Migraine Based on Data Mining [Letter]

Shen Z, Zhou C, Lin X

Journal of Pain Research 2025, 18:3359-3360

Published Date: 3 July 2025

Intravenous Streptozotocin Induces Variants in Painful Diabetic Peripheral Neuropathy in Female Mice

Hagenimana MA, Green AR, Tierney JA, Lenert ME, Burton MD

Journal of Pain Research 2025, 18:3345-3357

Published Date: 2 July 2025

Expert Opinion

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

A Proposed Diagnostic and Treatment Algorithm for the Management of Lumbar Discogenic Pain

Lorio MP, Beall DP, Myers TJ, Naidu RK, McRoberts WP, Davis TT, Gage EG, Calodney AK, Verrills P, De Palma MJ, Amirdelfan K, Block JE

Journal of Pain Research 2025, 18:3331-3343

Published Date: 1 July 2025

Efficacy and Safety of Kilohertz Frequency Alternating Current with Non-Invasive Electrodes for Treatment of Neuropathic Pain After Spinal Cord Injury: A Randomized, Single-Blind, Sham-Controlled Study

Shuai N, Zhu Y, Xiao Y, Yu B

Journal of Pain Research 2025, 18:3321-3330

Published Date: 1 July 2025

A Call to Action: Elevating Critical Appraisal Training in Pain Medicine

Hao D, Davis D, Schatman ME

Journal of Pain Research 2025, 18:3317-3320

Published Date: 30 June 2025

Editorial Commitment to Trust and Integrity in Science: Implications for Pain and Anesthesiology Research

Palermo TM, Bouhassira D, Davis KD, Hemmings Jnr HC, Hurley RW, Katz J, Pandit J, Price T, Schatman ME, Schwarz SKW, Turk D, Van de Velde M, Wiles M, Yaksh T, Yarnitsky D

Journal of Pain Research 2025, 18:3309-3316

Published Date: 1 July 2025

Efficacy and Central Mechanism of Acupuncture Treatment for Subacute Nonspecific Low Back Pain: A Clinical Neuroimaging Protocol

Ren J, Gao Z, Chang BY, Cui MJ, Wang HJ

Journal of Pain Research 2025, 18:3299-3308

Published Date: 30 June 2025

Electroacupuncture Prevent and Treat Perioperative Cognitive Impairment in Elderly Patients Undergoing Hip Surgery: A Protocol for a Randomized Controlled Trial

Fang Q, Xie J, Zheng S, Hou Y, Wu M, Chen Y, Yang Y, Wang G, Li J

Journal of Pain Research 2025, 18:3289-3297

Published Date: 28 June 2025

The Applications and Prescriptions of Motion Style Acupuncture Treatment for Musculoskeletal Pain: A Scoping Review of Clinical Controlled Trials

Chen Y, Zhu F, Zhu Y, Duan Y, Bai Z

Journal of Pain Research 2025, 18:3275-3287

Published Date: 28 June 2025

Clinical Efficacy of Acupuncture in the Treatment of Uterine Contraction Pain Post-Cesarean Section: Protocol of a Randomized Controlled Trial

Deng Y, Li Z, Zhang T, Tang X, Luo Y, Li Q, Zhang S, Liu Z, Tang D, Ai Z, Guo T, Liang F

Journal of Pain Research 2025, 18:3263-3274

Published Date: 28 June 2025

Epigenetics and Herbs: Potential Therapeutic Strategies for Osteoarthritis of the Knee

Zheng Y, Wang J, Wang L, Zheng Y, Qi W

Journal of Pain Research 2025, 18:3217-3261

Published Date: 26 June 2025

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Clinically Reducing/Eliminating Chronic Neuropathic Pain by Bridging Peripheral Nerve Gaps with an Autograft within a PRP-Filled Collagen Tube

Kuffler DP, Reyes O, Sosa IJ, Micheo WF, Santiago-Figueroa JM, Foy CA

Journal of Pain Research 2025, 18:3207-3216

Published Date: 27 June 2025

Evaluating Triptan Safety in Pediatric Migraine Management: A Comprehensive Pharmacovigilance Analysis

Chen J, Huang S, Chen Y, Luo C, Li Y

Journal of Pain Research 2025, 18:3185-3205

Published Date: 27 June 2025

Global, Regional and National Burden of Low Back Pain in Adolescents Aged 10–19 years, 1990–2021: A Systematic Analysis of the Global Burden of Disease Study 2021

Wang S, Zhang S, Li M, Chen S, Chen Y, Song Y, Zhang X

Journal of Pain Research 2025, 18:3171-3183

Published Date: 26 June 2025

Assessing the Causal Effect of Pulse Pressure on Migraine Risk: A Mendelian Randomization Study

Xu H, Qin X, Feng Z, You S

Journal of Pain Research 2025, 18:3159-3170

Published Date: 25 June 2025

Hypervigilance to Pain May Predict the Transition from Subacute to Chronic Back Pain: A Longitudinal Observational Study

Zhang W, Löffler M, Usai K, Mišić M, Nees F, Flor H

Journal of Pain Research 2025, 18:3141-3158

Published Date: 25 June 2025

Expert Opinion

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Consensus Guidelines from the American Society of Pain and Neuroscience for the Use of 60-Day Peripheral Nerve Stimulation Therapy. A NEURON Living Guideline Project

Gill B, Tidwell C, Hagedorn JM, Moreira AM, Lawandy M, Boyett B, Schappell J, Latif U, Pritzlaff S, Skaribas I, Kalia H, Sheth S, Schnur M, Li S, Lester D, Ellico T, Naidu R, Russo D, Massey C, Ottestad E, Vorenkamp K, Vucetic H, Pingree MJ, Abejón D, Desai MJ, Dickerson D, Gulati A, Sayed D, Deer TR

Journal of Pain Research 2025, 18:3117-3139

Published Date: 24 June 2025

The Causal Correlation Between Gastroesophageal Reflux Disease and Chronic Widespread Pain: A Bidirectional Mendelian Randomization Study

Chen M, Tu H, Zhou J, Zhang Y, Wen S, Xiao Y, He L

Journal of Pain Research 2025, 18:3107-3115

Published Date: 24 June 2025

Evaluating Physician Knowledge of Data Privacy and Cybersecurity Risks in Neuromodulation: An Online Cross-Sectional Survey

Martin E, Petersen E, Shah JR

Journal of Pain Research 2025, 18:3101-3106

Published Date: 24 June 2025

Effectiveness of Combination of Thunder Fire Moxibustion with Other Forms of Traditional Chinese Medicine for Osteoarthritis Knee: A Meta-Analysis

Wei W, Qin Y, Lin J

Journal of Pain Research 2025, 18:3087-3099

Published Date: 21 June 2025

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

The Mediating Role of Depression in the Relationship Between Perceived Injustice and Pain Intensity Among Fibromyalgia Patients

Raev S, Aloush V, Gilam G, Elkana O

Journal of Pain Research 2025, 18:3077-3085

Published Date: 19 June 2025

CT Angiographic Evaluation of Superior Gluteal Artery Branches in Lateral Sacroiliac Joint Fusion: A Pilot Study to Inform Preoperative Surgical Planning and Anatomic Parameters

Mallard CJ, Harned ME, Grider JS

Journal of Pain Research 2025, 18:3069-3075

Published Date: 19 June 2025

Exploration of the Application Rules and Clinical Significance of Acupoints in Acupuncture Treatment of Migraine Based on Data Mining

He Y, Wang X, Liu M, Li L, Han T, Wu Y, Li X

Journal of Pain Research 2025, 18:3049-3067

Published Date: 18 June 2025

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Efficacy and Temporal Dynamics of Genicular Nerve Block in Primary and Secondary Knee Osteoarthritis for Pain and Function: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Li Z, Bai Y, Liu C, Gu Y

Journal of Pain Research 2025, 18:3037-3048

Published Date: 17 June 2025

Acupotomy for Musculoskeletal Pain: Exploring Therapeutic Potential and Future Directions

Hu J, Tong H, Zhang J, Jiang L

Journal of Pain Research 2025, 18:3027-3036

Published Date: 17 June 2025

Transcutaneous Electrical Acupoint Stimulation (TEAS) Facilitates Postoperative Recovery in Day Lung Cancer Surgery: A Randomized Controlled Trial

Wu S, Lou J, Zou H, Wang W, Zhang Y, Xu Y, Hou X, Wu J

Journal of Pain Research 2025, 18:3017-3026

Published Date: 17 June 2025

Mid-Term Functional Recovery After ACDF and ACCF in the Treatment of Adjacent Two-Level Cervical Spondylosis: A Comparative Study

Wang X, Huang D, Han J, Luo J, Wang Y

Journal of Pain Research 2025, 18:3009-3016

Published Date: 17 June 2025

Differences in the Effectiveness of Different Physical Therapy Modalities in the Treatment of Delayed-Onset Muscle Soreness: A Systematic Review and Bayesian Network Meta-Analysis

Chen J, Hu Q, Hu J, Liu S, Yin L

Journal of Pain Research 2025, 18:2993-3008

Published Date: 15 June 2025

Effective Dosage of Ciprofol for the Induction of General Anesthesia Across Diverse Age Groups in Adults: A Single-Center, Prospective, Non-Randomized Sequential Trial

Deng L, Zhang C, Tan M, Zeng W, Luo G, Li P

Journal of Pain Research 2025, 18:2983-2992

Published Date: 14 June 2025

Original Research

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Ultrasound-Guided the Prevertebral Fascia Incise and the C5 Root Hydrodissection for the Treatment of Neurogenic Thoracic Outlet Syndrome: an Application Study

Liao Z, Zhou Y, Cao W

Journal of Pain Research 2025, 18:2973-2982

Published Date: 14 June 2025

Patient Perceptions on Opioid Therapy for Acute Pain Management in the Emergency Department and Post-Surgical Settings: A Qualitative Study

Lucey E, Dean E, Chapman BP, Perugini R, Chai P, Goldfine CE, Carreiro S

Journal of Pain Research 2025, 18:2961-2972

Published Date: 14 June 2025

Effect of Locoregional Vs General Anesthesia on Incidence of Delayed Neurocognitive Recovery in Patients Undergoing Hip Fracture Surgery: A Randomized Controlled Trial

Xie S, Zhao X, Zhao Z, Gui M, Cao X, Shen X, Luo J, Chen X, Xia Y, Yu B

Journal of Pain Research 2025, 18:2947-2960

Published Date: 12 June 2025

A Multi-Site, Randomized, Parallel-Group, Controlled Trial of Virtually-Delivered Sahaj Samadhi Meditation for the Management of Moderate Depressive Symptoms in Chronic Pain

Cheng DK, Simpson R, Moineddin R, Katz J, Mulsant BH, Vasudev A, Greiver M, Hosseiny F, Inzitari M, Newman RI, Rivlin L, Foat KD, Furlan AD, Flannery JF, Telner D, Bosma R, Naimer M, Chung C, Pinto AD, Nelson MLA, Upshur R, Sud A

Journal of Pain Research 2025, 18:2925-2946

Published Date: 13 June 2025

Fu’s Subcutaneous Needling Combined with Kinematic Acupuncture versus Electroacupuncture in the Treatment of Cervical Spondylotic Radiculopathy: A Randomized Controlled Trial [Letter]

Pan X, Liu Q

Journal of Pain Research 2025, 18:2923-2924

Published Date: 12 June 2025

Clinical Efficacy of Electroacupuncture in the Treatment of Chronic Neck Pain: A Randomized Clinical Trial

Li W, Liu X, Lin J, Huang J, Li S, Xu N, Fu W, Liu J

Journal of Pain Research 2025, 18:2909-2922

Published Date: 11 June 2025

Original Research

Opioids and Substance Abuse

Exploring Racial Disparities in Chronic Pain Management

Vargas AJ, Tobey-Moore L, Curran GM, Elkhateb R, Sexton KW, Bailey BJ, Nagel C, Goree JH

Journal of Pain Research 2025, 18:2901-2908

Published Date: 9 June 2025

Acupuncture as an Adjunctive Therapy to Etoricoxib for Patients with Acute Gouty Arthritis: Protocol for a Multicenter Randomized Controlled Trial

Wang YR, Liu CZ, Cong Y, Xi YW, Xu YY, Li B, Zhou Y, Tu JF, Fu YM, Chen W, Wang LQ, Shi GX

Journal of Pain Research 2025, 18:2889-2900

Published Date: 9 June 2025

Posterior Percutaneous Endoscopic Cervical Discectomy for Single-Segment Cervical Spondylotic Radiculopathy: A Retrospective Study with Minimum 3-Year Follow-Up

Wang X, Li T, Li Y, Long Y

Journal of Pain Research 2025, 18:2879-2888

Published Date: 9 June 2025

Mechanistic Study on the Therapeutic Effects of Juanbi Lijieqing Formula in a Rat Model of Gouty Arthritis with Hyperuricemia

Lu Y, Lu C, Jian G, Xiong H, Shu Y

Journal of Pain Research 2025, 18:2865-2877

Published Date: 9 June 2025

Altered Brain Functional Connectivity and Neurometabolite Correlations in Orofacial Chronic Pain with Central Sensitization

Terumitsu M, Takado Y, Fukuda KI, Kato E, Tanaka S, Tha KK

Journal of Pain Research 2025, 18:2849-2863

Published Date: 9 June 2025

Machine Learning Analysis to Identify Predictive Factors of Caudal Epidural Pulse Radiofrequency in the Treatment of Coccygodynia

Sir E, Aydogan S, Batur Sir GD, Celenlioglu AE

Journal of Pain Research 2025, 18:2839-2848

Published Date: 7 June 2025

A Cost Effectiveness Analysis of Spinal Cord Stimulation versus Conventional Medical Management for the Treatment of Low Back Pain Using Data from DISTINCT RCT and Medical Claims from a U.S. Commercial Payer Database

Deer T, Heros R, Scarfo K, Gilligan C, Jameson J, Pilitsis JG, Desai MJ, Panchalingam T, Goates S, Benison AM, Okaro U, Falowski S

Journal of Pain Research 2025, 18:2823-2838

Published Date: 7 June 2025

Effect of Telemedicine-Supported Structured Exercise Program in Patients with Chronic Low Back Pain: Study Protocol for a Randomized Controlled Trial

Feng Y, Jia C, Liu H, Bao T, Wang C, Wang Z, Huang J, Jiang Y, Wang X, Zhang R, Zhang Y, Zhang S, Zhu S, He C

Journal of Pain Research 2025, 18:2809-2822

Published Date: 7 June 2025

Commentary

Pharmacology

Suzetrigine Approval Breaks a 25-Year Silence: A New Era in Non-Opioid Acute Pain Management

Sibomana O, Okereke M, Hakayuwa CM

Journal of Pain Research 2025, 18:2805-2808

Published Date: 6 June 2025

Comprehensive Review on Personalized Pain Assessment and Multimodal Interventions for Postoperative Recovery Optimization

Xu J, Liu X, Zhao J, Zhao J, Li H, Ye H, Ai S

Journal of Pain Research 2025, 18:2791-2804

Published Date: 5 June 2025

Spinal Cord Stimulation Alleviates Sensitization of Neuropathic Pain by Upregulating G Protein-Coupled Receptors to Inhibit Overexpression of Cav2.2 and Its Downstream Excitatory Neurotransmitters

Liu SL, Zhang HE, Kang JY, Ji HY, Cai ZH, Qi SH, Liu SS, Zhou HC

Journal of Pain Research 2025, 18:2775-2790

Published Date: 5 June 2025

Postoperative Pain Management Strategies Following Peroral Endoscopic Myotomy (POEM): A Review

Lu J, Ji W, Sang C, Wang Z, Bo L

Journal of Pain Research 2025, 18:2761-2773

Published Date: 31 May 2025

A Real-World Study of Cetylated Fatty Acids Food Supplement Administration in Italian Adults for Sub-Acute or Chronic Musculoskeletal Pain

Lanzisera R, Gervasoni F, Rossato MS, Tarantino G, Lo Mauro A, Geri E

Journal of Pain Research 2025, 18:2751-2760

Published Date: 30 May 2025

Characterizing the Optimal Diversity Training Programs for Physicians: A Survey sponsored by Pacific Spine and Pain Society

Gendreau JL, Bauman MMJ, Brown NJ, Alfonzo Horowitz M, Chakravarti S, Mehkri Y, Grovey B, Lee E, Lee G, Cornidez E, Bhandal HS, Pope JE

Journal of Pain Research 2025, 18:2739-2750

Published Date: 27 May 2025

Exploring the Interaction Mechanisms of Antibody-Mediated Immune Responses with Gout and Rheumatoid Arthritis Through a Bidirectional Two-Sample Mendelian Randomization Study

Zhou H, Liu Q, Lv D, Zheng Y, Xing Z

Journal of Pain Research 2025, 18:2707-2738

Published Date: 27 May 2025

Examining the Effects of Interventional Pain Management Staff Controlled Substance Agreement Education for Patients with Chronic Non-Cancer Intrathecal Drug Delivery Device Opioid Therapy: A Retrospective Review

Hoffmann C, McDonald T, Gladis B, Schatman ME, Pittelkow TP

Journal of Pain Research 2025, 18:2699-2706

Published Date: 26 May 2025

Clinical Efficacy of Single- vs Dual-Level Transversus Abdominis Plane Block for Lower Segment Cesarean Section: A Prospective, Randomized, Controlled Study

Cao WN, Qiu B, Li Y, Hu CL, Liu HC, Yuan KM, Wang FY

Journal of Pain Research 2025, 18:2689-2698

Published Date: 26 May 2025

Effect of Pericapsular Nerve Group Block with Wound Infiltration vs Modified Supra-Inguinal Fascia Iliaca Block on Postoperative Analgesia in Adult Patients Undergoing Total Hip Arthroplasty – A Randomized Clinical Trial

Huang Y, Peng S, Wang J, Liu L, Dong CS

Journal of Pain Research 2025, 18:2679-2688

Published Date: 24 May 2025

Effects of Transcutaneous Electrical Acustimulation on Patients with Fibromyalgia Syndrome: Study Protocol of a Randomized, Double-Blind, Sham-Controlled Trial

Li Y, Fan B, Wang X, Hu N, Zhou X, Zhang Y, Mao P, Li Y

Journal of Pain Research 2025, 18:2663-2677

Published Date: 24 May 2025

“Do Doctors and Patients Have Different Understandings of Pain?” – A Pilot Study of Different Perspectives and Understandings of Pain in Clinical Pain Research

Gormsen LK

Journal of Pain Research 2025, 18:2651-2662

Published Date: 24 May 2025

Indolepropionic Acid Attenuates CFA-Induced Inflammatory Pain in Mice

Ao RF, Yong HR, Hu YT, Huang YS, Gao JW, Tu C, Zhuang JS, Zhong ZM

Journal of Pain Research 2025, 18:2643-2650

Published Date: 23 May 2025

Clinical Trial Report

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Effectiveness of Jingjin Therapy for Non-Specific Chronic Neck Pain with Extension Dysfunction: A Randomised Controlled Trial

Gong Z, Gao Y, Liu W, Li W, Wu X, Li J

Journal of Pain Research 2025, 18:2631-2642

Published Date: 23 May 2025

NMRAL1 as a Causal Factor in Postherpetic Neuralgia: A Proteome-Wide Mendelian Randomization Study

Ye H, Wang Y, Shi Y, Wu Y, Xu Q, Huang S

Journal of Pain Research 2025, 18:2623-2629

Published Date: 23 May 2025

Trajectory of Self-Reported Pain and Association with Quality of Life in Patients with Perianal Abscesses After Surgery

Gao Y, Zhang L, Qian Q, Zhang H, Yao Y

Journal of Pain Research 2025, 18:2615-2622

Published Date: 23 May 2025

Five Critical Queries on Network Meta-Analysis: “Effective Yet Insignificant” Manipulative Therapy for Myofascial Pain Syndrome? [Response to Letter]

Chen J, Hu Q, Yin L, Zeng L, Liu S

Journal of Pain Research 2025, 18:2613-2614

Published Date: 23 May 2025

Navigating Pregnancy Testing in Chronic Pain Management for Women of Reproductive Age

Tamura S, Vardhan S, Breidenbach K, Shaparin N, Vydyanathan A, Gritsenko K

Journal of Pain Research 2025, 18:2605-2612

Published Date: 21 May 2025

The CXCL12/CXCR4 Axis: An Emerging Therapeutic Target for Chronic Pain

Chen Z, Xia Y, Liu B, Fang J, Hu Q

Journal of Pain Research 2025, 18:2583-2603

Published Date: 21 May 2025

Needs and Wishes Towards Sex- and Gender-Sensitive Chronic Pain Management: A Qualitative Study with German General Practitioners

Piotrowski A, Schmidt A, Seuken N, Goldberg L, Kufeld N, Kersting C, Bencheva V, Thürmann P, Mortsiefer A

Journal of Pain Research 2025, 18:2567-2581

Published Date: 20 May 2025

Predictors for Postoperative Nerve Recovery in Severe Carpal Tunnel Syndrome

Luo Z, Ma T, Tian S, Yu K, Tian D

Journal of Pain Research 2025, 18:2559-2565

Published Date: 19 May 2025

Risk of Acute Pain in Obese Patients Undergoing Atrial Fibrillation Ablation

Dong P, Wang H, Yan F, Zhang Z

Journal of Pain Research 2025, 18:2549-2557

Published Date: 20 May 2025

Effectiveness of Repetitive Peripheral Magnetic Stimulation (rPMS) in Relieving Post-Needling Soreness in Patient with Upper Trapezius Myofascial Pain Syndrome: A Double-Blind, Randomized Clinical Trial

Vearasilp A, Sukareechai C

Journal of Pain Research 2025, 18:2541-2548

Published Date: 20 May 2025

Review

Integrative/Acupuncture

Efficacy of Acupuncture and Pharmacotherapy for Migraine Prophylaxis: A Systematic Review and Meta-Analysis

Liu AR, Zhu Q, Li J, Cao Y, Pei T, Shi L

Journal of Pain Research 2025, 18:2521-2540

Published Date: 17 May 2025

Comparison of Surgical Anesthesia Onset Between Dural-Puncture Epidural and Standard Epidural Techniques for Emergency Cesarean Section: Protocol for a Randomized Controlled Trial

Zhou S, Cao X, Zhou Y, Xu Z

Journal of Pain Research 2025, 18:2509-2519

Published Date: 16 May 2025

Transforming Chronic Pain Management: Integrating Neuromodulation with Advanced Technologies to Tackle Cognitive Dysfunction – A Narrative Review

Green M, Hayley A, Gunnersen JM, Nazemian V, Cabble A, Thompson S, Chakravarthy K

Journal of Pain Research 2025, 18:2497-2507

Published Date: 16 May 2025

Analgesic and Hemodynamic Effects of Dexmedetomidine–Ketamine vs Fentanyl–Ketamine in Healthy Volunteers: A Randomized Trial

Green M, Hayley AC, Downey LA, Keane M, Kenneally ME, Chakravarthy K, Shehabi Y

Journal of Pain Research 2025, 18:2483-2496

Published Date: 16 May 2025

Absorbable Antibacterial Envelope Reduces Surgical Site Infections for Intrathecal Pain Pump Implants: A Retrospective Analysis

Robinson CL, Chiang MC, Patel AS, Chan KS, Ori A, Yong RJ, Ang SP

Journal of Pain Research 2025, 18:2479-2482

Published Date: 15 May 2025

The Clinical Effect of Electroacupuncture Combined with Surround Needling in the Treatment of Acute Lateral Ankle Sprain Based on Musculoskeletal Ultrasound Imaging Technology: A Protocol for a Single-Centre, Randomized, Controlled Trial

Chen L, Hu Q, Gao H, Tang D

Journal of Pain Research 2025, 18:2467-2478

Published Date: 15 May 2025

Balanced Opioid-Free Anesthesia on Chronic Postsurgical Pain After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial Protocol

Huo WW, Qian J, Zhao HX, Dou W, Chen SM, Ji FH, Peng K

Journal of Pain Research 2025, 18:2459-2466

Published Date: 15 May 2025

Outcomes Of Intraarticular Corticosteroid Injections into the Cervical Facet Joint Based on Single-Photon Emission Computed Tomography Imaging

Yang S, Chang MC

Journal of Pain Research 2025, 18:2453-2458

Published Date: 14 May 2025

Clinical Trial Report

Acute Pain and Perioperative Care

Effects of Intrathecal Sufentanil at Different Doses on Postoperative Pain Relief and Opioid Consumption in Elderly Patients Undergoing Lower Limb Orthopedic Surgery: A Randomized Controlled Trial

Li Y, Gu Y, Liu W, Liu X, Wang F, Tian B, Zhou W, Ye Q

Journal of Pain Research 2025, 18:2439-2451

Published Date: 15 May 2025

Comparison of Costotransverse Foramen Block with Thoracic Paravertebral Block and Erector Spinae Plane Block for Patients Undergoing Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Non-Inferiority Trial

Li J, Shao P, Wen H, Ma D, Yang L, He J, Jiang J

Journal of Pain Research 2025, 18:2427-2438

Published Date: 13 May 2025

Healthcare Workers’ Pain Management-Correlated Barriers and Self-Efficacy at Teaching Hospitals in the City of Ismailia

Elmansy FM, Elbqry MG, Al-Ahdal SA, Ashmieg FSO, Elgazzar SE, Nasir PO, Abdullahi NM

Journal of Pain Research 2025, 18:2417-2425

Published Date: 13 May 2025

Effect of Low Thoracic Paravertebral Block via the Arcuate Ligament Under Direct Visualization on the Quality of Postoperative Recovery After Laparoscopic Donor Nephrectomy for Living-Donor Kidney Transplantation: Study Protocol for a Prospective, Blinded, Randomized Controlled Clinical Trial

Cui L, Zhu Y, Liu S, Zhang L, Zhu Q, Wang Y, Ma D

Journal of Pain Research 2025, 18:2409-2416

Published Date: 13 May 2025

Five Critical Queries on Network Meta-Analysis: “Effective Yet Insignificant” Manipulative Therapy for Myofascial Pain Syndrome? [Letter]

Chen Z, Li S, Yang R, Liu R

Journal of Pain Research 2025, 18:2407-2408

Published Date: 12 May 2025

Evaluation of the Therapeutic Efficacy of Entrapment Neuropathy Unties (ENU) Pharmacopuncture in Neuropathic Pain Caused by Sciatic Nerve Ligation in Mice

Kweon B, Kim DU, Park K, Lee S, Youn Y, Park HJ, Shim HS, Yoo J, Lee YK, Bae GS, Choi Y

Journal of Pain Research 2025, 18:2393-2405

Published Date: 12 May 2025

Mechanistic and Clinical Evaluation of Lever-Positioning Manipulation in Lumbar Disc Herniation: A Study Protocol for a Randomized Controlled Trial Using Rs-fMRI

Xie Y, Du H, Liang A, Yao J, Qu J, Zeng X

Journal of Pain Research 2025, 18:2379-2392

Published Date: 12 May 2025

Quality or Quantity? The Quiet Influence of Industry-Sponsored Centers of Excellence

Pritzlaff SG, Flower V, Salmasi V, Sheth SJ, Schatman ME

Journal of Pain Research 2025, 18:2375-2377

Published Date: 9 May 2025

A Commentary on Acupoints for Headache with Blood Stasis Syndrome: A Literature Study Based on Data Mining Technology [Letter]

Zheng Y, He Y, Xu Y

Journal of Pain Research 2025, 18:2373-2374

Published Date: 9 May 2025

Serious Adverse Drug Reactions to Long-Term Oral Liquid Morphine in Patients with Chronic Pain: A Cross-Sectional Survey in Palliative Care

Duncan B, Natuhwera G, Nassuuna D, Katusabe R, Kasozi H, Acuda W

Journal of Pain Research 2025, 18:2361-2371

Published Date: 8 May 2025

The Need for Urgent Action and Reform: Is the Veterans Administration’s Pain Care Under Fire?

Chakravarthy K, Schatman ME

Journal of Pain Research 2025, 18:2359-2360

Published Date: 8 May 2025

Multisite Chronic Pain and the Risk of Breast Cancer and Its Subtypes: A Mendelian Randomization Study

Li W, Liu J, Wang T, Hou Y, Bao J, Song Y, Liu L, Ge S, Shang Y, Wang R, Zhang M, Xu M

Journal of Pain Research 2025, 18:2343-2357

Published Date: 7 May 2025

Analyzing Trends in the Pain Fellowship Match – A Survey of Program Directors

Jueng J, Pritzlaff SG, Mehta N, Gulati A, Schatman ME, Wahezi SE, Day M, Durbhakula S, Pak DJ

Journal of Pain Research 2025, 18:2335-2341

Published Date: 7 May 2025

A Systematic Review and Meta-Analysis of Randomized Controlled Trials for Electroacupuncture Treatment of Migraine

Song S, Chen H

Journal of Pain Research 2025, 18:2321-2333

Published Date: 6 May 2025

A Randomized, Sham-Controlled Trial on the Efficacy and Safety of Electroacupuncture for Lumbar Disc Herniation with Radiculopathy: Rationale and Study Protocol

Yang Y, Liu L, Yuan L, Liu X, Ding H, Zhou X, Cao Q

Journal of Pain Research 2025, 18:2307-2319

Published Date: 5 May 2025

Review

Acute Pain and Perioperative Care

Postoperative Sore Throat After Tracheal Intubation: An Updated Narrative Review and Call for Action

Chen Z, Zuo Z, Zhang L, Gong M, Ye Y, Jin Y, Zhao X

Journal of Pain Research 2025, 18:2285-2306

Published Date: 6 May 2025

Inflammation Factors Mediate Association of Muscle Mass and Migraine: NHANES 1999–2004 and Mendelian Randomization

Jia C, Li H, Yang S, Liu Y, Liu L, Ma A, Zhang L

Journal of Pain Research 2025, 18:2269-2283

Published Date: 2 May 2025

Perspective Articles as Catalysts for Innovation: Addressing Critiques on Traditional Chinese Rehabilitation Exercise for Myofascial Pain [Response to Letter]

Liu X, Zhang J

Journal of Pain Research 2025, 18:2265-2267

Published Date: 29 April 2025

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

High Prevalence of Small-Fiber Neuropathy in Patients with Tarlov Cysts: Toward a More Comprehensive Clinical Understanding

Hulens M, Zajonc P, Bruyninckx F, Rasschaert R, De Mulder P, Bervoets C, Dankaerts W

Journal of Pain Research 2025, 18:2241-2263

Published Date: 30 April 2025

Risk Stratification for Postoperative Opioid Induced Respiratory Depression: A Retrospective Case-Control Analysis of Existing Validated Tools

Hutcheson S, Pehrson A, Gassert RB, Guffey E, Shanahan PC, Sisk L, Patton S, Solla CA

Journal of Pain Research 2025, 18:2233-2240

Published Date: 28 April 2025

Comparative Evaluation of Efficacy and Complications Between Biportal Endoscopic Lumbar Interbody Fusion and Minimally Invasive Transforaminal Lumbar Interbody Fusion for Lumbar Degenerative Diseases: A Systematic Review and Meta-Analysis

Hu Q, Xiao K, Nan JN, Jhang SW, Chen CM, Lin GX

Journal of Pain Research 2025, 18:2215-2231

Published Date: 26 April 2025

Radiofrequency for Chronic Knee Pain: A Literature Review

Shang C, Sun N, Lv Z, Yin D, Feng C

Journal of Pain Research 2025, 18:2203-2213

Published Date: 26 April 2025

Causal Relationship Between Psychosocial Factors and Neck Pain: A Two-Sample Mendelian Randomization Study

Liang H, Wu Q, Yang S, Zhang S, Miao J, Jin H, Wang X

Journal of Pain Research 2025, 18:2191-2201

Published Date: 25 April 2025

Analysis of Electroacupuncture Parameters for Irritable Bowel Syndrome: A Data Mining Approach

Tang Y, Tang X, Wen Q

Journal of Pain Research 2025, 18:2175-2189

Published Date: 23 April 2025

“Zhibian (BL54) to Shuidao (ST28)” Acupuncture Manipulation Combined with Analgesics in Postoperative Pain Management for Patients with Mixed Hemorrhoids: A Randomized Controlled Trial Protocol

Wang T, Gao JQ, Chang M, Ma MC, Wang YT, Guo TN, Zhang YL, Gao Z, Wang HJ, Cao YX

Journal of Pain Research 2025, 18:2163-2174

Published Date: 24 April 2025

Device Evaluation, Treatment, and Explantation Recommendations (DETER): Review and Best Practices for Managing Neuromodulation Device Infections

Pritzlaff SG, Goree JH, Dare RK, D’Souza RS, Lee DW, Dudas AA, Kalia H, Orhurhu V, Singh N, Hagedorn JM, Mousavi A, James W, Leong MS, Meacham KW, Gulati A, Sheth SJ, Pena I, Shah JR, Murphy MZ, Nashi SE, Nasseri M, Khoury AM, Dorsi MJ, Falowski SM, Petersen EA, Tomycz ND, Wahezi S, Chakravarthy KV, Pope JE, Schatman ME, Amirdelfan K, Sayed D, Deer TR

Journal of Pain Research 2025, 18:2147-2161

Published Date: 23 April 2025

Opioid-Free versus Opioid-Sparing Anesthesia for Postoperative Pain and Early Recovery After Laparoscopic Cholecystectomy: A Randomized Controlled Trial

Xiong M, Liu Y, Liang Y, Wang H, Zhang L, Zhang Z, Fang M

Journal of Pain Research 2025, 18:2137-2146

Published Date: 23 April 2025

Research on the Developmental Trajectory of Movement-Evoked Pain and Its Potential Predictors in Patients After Knee Arthroplasty

Ai S, Zhao S, Yan L, Hu H, Niu P, Zhu Y, Zheng M

Journal of Pain Research 2025, 18:2127-2136

Published Date: 21 April 2025

Articaine Needle - Free Anesthesia Vs Conventional Anesthesia in Root Canal Treatment of Irreversible Pulpitis in Permanent Teeth: A Prospective Study on Anesthetic Efficacy and Effects on Pain

Qian S, Meng Z, Zhang H, Li K, Zhang F, Zhang S, Liu J, Zhou Z

Journal of Pain Research 2025, 18:2115-2125

Published Date: 21 April 2025

Evaluation of Clinical Symptoms of Unilateral S1 Nerve Injury Caused by Disc Herniation the via High Resolution MRI and DTI

Zhang C, Hao W, Guo X, Zhang Y, Fu H, Zhang J

Journal of Pain Research 2025, 18:2105-2114

Published Date: 18 April 2025

Migraine Headache and Its Related Disability Factors Among University Students in Jordan: A Cross-Sectional Study

Almomani MA, Almomani BA, Al-Sawalha NA, Alqudah AA

Journal of Pain Research 2025, 18:2093-2104

Published Date: 16 April 2025

Exploring the Multifactorial Predictors of Pain in Chronic Musculoskeletal Pain: A Regression-Based Study

González-de-la-Flor A, Bravo-Aguilar M, Almazán-Polo J, García-Pérez-de-Sevilla G, Martínez-Lozano P, Romero-Morales C

Journal of Pain Research 2025, 18:2081-2091

Published Date: 16 April 2025

Percutaneous Endoscopic Backhand Holding (EBH) Technique for Extraforaminal Lumbar Disc Herniations: A Modified Operative Technique

Kong M, Gao C, Hao M, Ma X, Zhao J, Luan J, Lin Y, Jin C, Li Q

Journal of Pain Research 2025, 18:2069-2080

Published Date: 16 April 2025

Exploration of Key Brain Regions Involved in Acupuncture and Moxibustion Analgesia: An Imaging-Based Study

He L, Zhou R, Hou S, Huang D, Zhao X, Wang M, Huang M, Yin T, Yin H, Yu S

Journal of Pain Research 2025, 18:2051-2067

Published Date: 15 April 2025

Editorial

Pharmacology

Suzetrigine: Is This What We Have Been Waiting for or Just the Beginning?

Robinson CL, Schatman ME, Hasoon J, Chung M, Emerick T, Lo Bianco G, Ashina S, Yong RJ

Journal of Pain Research 2025, 18:2047-2049

Published Date: 15 April 2025

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Manual Therapy for Cervical Radiculopathy: Effects on Neck Disability and Pain – A Systematic Review and Network Meta-Analysis

Xu X, Ling Y

Journal of Pain Research 2025, 18:2035-2045

Published Date: 14 April 2025

Investigation of the Impact of a Low-Carbohydrate Diet on The Chronic Pain Experience Among Adults with an Acquired Limb Loss: A Pilot Study

Wiggins AM, Benlolo PM, Suresh SV, Goldfeiz NM, Carr CJ, Sorge RE

Journal of Pain Research 2025, 18:2025-2034

Published Date: 13 April 2025

Acupotomy Ameliorates KOA Related Chondrocyte Premature Senescence Through YAP/FOXD1 Pathway

Ma Y, Hu T, Liu N, Guo C, Xing L, Ma W, Cui Y, Chen X

Journal of Pain Research 2025, 18:2011-2023

Published Date: 12 April 2025

Suicidal Ideation and Self-Injury in Trigeminal Neuralgia

Fishbein NS, Bakhshaie J, Greenberg J

Journal of Pain Research 2025, 18:2003-2010

Published Date: 12 April 2025

The Relationship Between Psychosocial Factors and Response to Epidural Steroid Injection for Chronic Lumbosacral Radicular Pain: A Prospective Pilot Study

Stensland M, Sanford E, Houle TT, McGeary C, Cobos BA, Lugosi S, Lehman L, Nabity PS, Covell C, Fitzgerald E, Mojallal M, Reed DE, Pangarkar S, Eapen BC, Nanda U, McCormick ZL, McGeary D

Journal of Pain Research 2025, 18:1991-2002

Published Date: 11 April 2025

Disease Burden of Neck Pain in China from 1990 to 2021 and Its Prediction for 2042: The Global Burden of Disease Study 2021

Wei J, Yang K, Xue J, Luo M, Peng W, Yin X, Sun W, Gao C, Teng G, Yin H, Feng M, Li L, Sun K, Zhang W

Journal of Pain Research 2025, 18:1975-1990

Published Date: 11 April 2025

Shallow Acupuncture for Chronic Neck Pain: A Multicenter Randomized Controlled Trial Protocol with fMRI and DTI

Lin J, Gu Z, Zhou P, Huang W, Ou A, Zhao Q, Xu Z

Journal of Pain Research 2025, 18:1963-1973

Published Date: 11 April 2025

Explicit Motor Imaging Abilities Are Similar in Complex Regional Pain Syndrome, Chronic Limb Pain and Healthy Individuals: A Cross-Sectional Study

Cohen-aknine G, Mottet D, Homs AF, Mura T, Jedryka F, Dupeyron AF

Journal of Pain Research 2025, 18:1949-1961

Published Date: 11 April 2025

Postulate of the Existence of a ‘Nocistat’: Rationale and Implications for Novel Analgesics

Raffa RB, Fink W, Tripathi AD

Journal of Pain Research 2025, 18:1945-1947

Published Date: 10 April 2025

Comparison of Closed Irrigation and Drainage vs Repeated Wound Dressing Changes for Iliac Crest Bone Donor Site Infection in Spine Surgery

Li X, Xiao Q, Zeng JH

Journal of Pain Research 2025, 18:1935-1943

Published Date: 9 April 2025

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Manipulative Treatment of Myofascial Pain Syndrome: A Network Meta-Analysis Based on Randomized Controlled Trials

Chen J, Yin L, Hu Q, Liu S, Zeng L

Journal of Pain Research 2025, 18:1923-1933

Published Date: 10 April 2025

LASSO Logistic Regression for Predicting Postoperative Severe Pain After Hepatic Hemangioma Ablation

Gao R, Xu F, Song Y, Ke S, Kong J, Wang S, Sun W, Gao J

Journal of Pain Research 2025, 18:1909-1921

Published Date: 9 April 2025

Durability of Supplemental Nucleus Pulposus Allograft in Patients with Lumbar Discogenic Pain

Costandi S, Beall DP, Davis TT, Amirdelfan K, Naidu RK, DePalma MJ, Yoon ES, Fleming JW, Block JE, Mekhail N

Journal of Pain Research 2025, 18:1901-1908

Published Date: 9 April 2025

Efficacy of Ultrasound-Guided Iliohypogastric and Ilioinguinal Nerve Block for Anesthesia in Pediatric Inguinal Surgery

Li P, Tang W

Journal of Pain Research 2025, 18:1891-1899

Published Date: 8 April 2025

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Treatment Modalities for Aromatase Inhibitor-Associated Musculoskeletal Syndrome (AIMSS): A Scoping Review of Prospective Treatment Studies

Bobo JA, Lubrano B, Rosario-Concepcion R, Cuartas-Abril A, Advani P, Chumsri S, Bruce BK

Journal of Pain Research 2025, 18:1853-1889

Published Date: 7 April 2025

Traditional Chinese Rehabilitation Exercise (TCRE) for Myofascial Pain—A Superficial Synthesis with Missed Opportunities [Letter]

Zhou Z, Liu Q

Journal of Pain Research 2025, 18:1851-1852

Published Date: 5 April 2025

Clinical Trial Report

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Impact of Propranolol and Psychologically Informed Intervention on Pain Sensitivity: Secondary Analysis from the Biopsychosocial Influence on Shoulder Pain Preclinical Randomized Trial

Bishop MD, Simon CB, Huo Y, Wallace MR, Borsa PA, Fillingim RB, Staud R, Wu SS, George SZ

Journal of Pain Research 2025, 18:1837-1850

Published Date: 5 April 2025

The Degeneration of Paraspinal Muscles and Its Correlation with the Postoperative Clinical Outcomes Following Minimally Invasive Transforaminal Lumbar Interbody Fusion (MIS-TLIF)

Hu W, Zhang K, Shi X, Yang G, Li A, Gao Y

Journal of Pain Research 2025, 18:1827-1836

Published Date: 5 April 2025

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Herpes Zoster in Pregnancy: Clinical Outcomes and Treatment Patterns from a Multicenter Retrospective Cohort

Xu H, Qin X, Feng Z, You S

Journal of Pain Research 2025, 18:1817-1826

Published Date: 4 April 2025

Real-World Pharmacovigilance Analysis of Adverse Events Associated with Liposomal Bupivacaine and Bupivacaine

Chen DX, Chen XM, Chen SM, Wang YD

Journal of Pain Research 2025, 18:1805-1816

Published Date: 3 April 2025

Association Between Educational Attainment and Chronic Pain: A Mediation Mendelian Randomization Study

Wang H, Liu M, Li H, Xu S

Journal of Pain Research 2025, 18:1793-1804

Published Date: 3 April 2025

Five-Step Knee Adjustment Manipulation Based on the ‘Muscle and Bone Balance’ Principle for Treating Knee Osteoarthritis: Study Protocol for a Randomized Controlled Trial

Da W, Liu S, Qian Q, Zhu B, Chen L, Xue F, Sun P, Xue C, Xue Y, Yang J, Du W, Ding C, Shi Q, Li X

Journal of Pain Research 2025, 18:1775-1791

Published Date: 2 April 2025

Ultrasound-Guided Sural Nerve and Tibial Nerve Block Provides Comparable Analgesia to Popliteal Sciatic Nerve Block Following Calcaneal Surgery: A Single Center Randomized Controlled Double-Blind Study

Yao J, Cai J, Lu Q, Huang X

Journal of Pain Research 2025, 18:1765-1773

Published Date: 1 April 2025

Original Research

Pain in Older Adults

The Placebo Hypoalgesic Response Is Reduced in Healthy Older Adults Showing a Decline in Executive Functioning

Rischer KM, Dierolf AM, Anton F, Montoya P, González-Roldán AM, van der Meulen M

Journal of Pain Research 2025, 18:1747-1763

Published Date: 1 April 2025

Latent Profile Analysis of Pain Catastrophizing in Post-Operative Lung Cancer Patients

Wu X, Xu T, Cai P, Shen S, Ji M, Liu Q, Wang X, Zhang M, Wang S, Gu D

Journal of Pain Research 2025, 18:1735-1745

Published Date: 1 April 2025

Genetic Evidence for Causal Effects of Immune Cell Subtypes on Postherpetic Neuralgia

Chen T, Tang S, Chen R, Ding W, Chen Y, Jian Z, Wu M, Jia M, Zhang X

Journal of Pain Research 2025, 18:1721-1734

Published Date: 31 March 2025

Efficacy of Percutaneous Spinal Endoscopic YESS Technique in Adjacent Segmental Disease Without Severe Instability After Lumbar Fusion Surgery: A Case Series

Zou H, Huang L, Zhao L, Li P, Xiao Q, Rong X

Journal of Pain Research 2025, 18:1711-1720

Published Date: 30 March 2025

Hippocampal Subfields Related to Cognitive Decline and Peripheral TIM-3 Levels in Elderly with Knee Osteoarthritis

Zhao B, Lian X, Zeng P, Wang Y, Cai G, Chen R, Liu J, Chen L

Journal of Pain Research 2025, 18:1697-1709

Published Date: 30 March 2025

Review

Opioids and Substance Abuse

Enhanced Recovery After Surgery (ERAS) Protocols in Orthopaedic Surgery: Opioids or Not Opioids?

Grossi P

Journal of Pain Research 2025, 18:1683-1695

Published Date: 28 March 2025

Efficacy of Acupuncture in Treating Nape Back Myofascial Pain Syndrome: a Comprehensive Systematic Review and Meta-Analysis

Zhang P, Zhang Y, Guo M

Journal of Pain Research 2025, 18:1667-1681

Published Date: 29 March 2025

Spectral Analysis of Bioelectrical Activity in Experimentally Provoked Referred Pain – Motor Alterations Related to the Network of Trigger Points

Konieczny M, Matuska J, Domaszewski P, Pakosz P, Herrero P, Santafe MM, Wotzka D, Zmarzły D, Skorupska E

Journal of Pain Research 2025, 18:1657-1666

Published Date: 26 March 2025

Effectiveness and Safety of Platelet-Rich Plasma Combined with Pulsed Radiofrequency to Treat Patients with Infraorbital Neuralgia: A Propensity Score-Matched Analysis of a Multi-Center, Prospective Cohort Protocol

Liu L, Yang D, Duan B, Luo F

Journal of Pain Research 2025, 18:1643-1656

Published Date: 26 March 2025

Impact of Socioeconomic Status on the Risk of Intervertebral Disc Degeneration and Low Back Pain in the European Population and the Mediating Role of Obesity-Related Traits: Evidence from a Mendelian Randomization Study

Long Z, Qin Q

Journal of Pain Research 2025, 18:1627-1641

Published Date: 26 March 2025

Subserratus Anterior Plane Block vs Thoracic Paravertebral Block for Postoperative Analgesia in Laparoscopic Radical Nephrectomy: Protocol for a Randomized Controlled, Double-Blind, Non-Inferiority Clinical Trial

Lin J, Wu H, Wen Z, Li Y, Jiang C, Lin B, Gu Y

Journal of Pain Research 2025, 18:1615-1625

Published Date: 25 March 2025

Risk Factors for Postoperative Pain in Pterygium Surgery Patients

Yang G, Li Q, Tian M, Liu M, Zhang T, Guo W, Li Q

Journal of Pain Research 2025, 18:1607-1614

Published Date: 25 March 2025

Comparative Analysis of Muscle Elasticity and Pathological Characteristics Between Affected and Unaffected Sides in Postherpetic Neuralgia Patients: Protocol for a Pilot Cohort Trail

Ji H, Ma J, Cui X, Huang Y

Journal of Pain Research 2025, 18:1597-1605

Published Date: 25 March 2025

Impact of Carotid Interventions on Headache Relief in Patients with Carotid Stenosis: a Retrospective Analysis of Carotid Endarterectomy Versus Stenting

Arslanturk O, Gur AK, Ada F, Keskin E

Journal of Pain Research 2025, 18:1587-1596

Published Date: 24 March 2025

Genetically Supported Causality Between Immune Cells Traits and Low Back Pain: A Bi-Directional Two-Sample Mendelian Randomization Study

Wang J, Zhu M, Liu Y, Zhang D, Yu S, Zhang J

Journal of Pain Research 2025, 18:1577-1585

Published Date: 24 March 2025

Original Research

Acute Pain and Perioperative Care

Suzetrigine, a Non-Opioid NaV1.8 Inhibitor With Broad Applicability for Moderate-to-Severe Acute Pain: A Phase 3 Single-Arm Study for Surgical or Non-Surgical Acute Pain

McCoun J, Winkle P, Solanki D, Urban J, Bertoch T, Oswald J, Swisher MW, Taber LA, Healey T, Jazic I, Correll DJ, Negulescu PA, Bozic C, Weiner SG

Journal of Pain Research 2025, 18:1569-1576

Published Date: 25 March 2025

Mentorship in Pain Medicine Fellowship: Addressing the Gaps and Advocating for Change

Wahezi SE, Yener U, Staats PS, Eshraghi Y, Day M, Schatman ME, Pritzlaff SG

Journal of Pain Research 2025, 18:1563-1567

Published Date: 24 March 2025

Day-to-Day Risk and Resilience Factors in the Context of Pediatric Post-Surgical Recovery – A Network Analysis of Intensive Longitudinal Data From Adolescents Undergoing Spinal Fusion Surgery and Their Parents

Thorsell Cederberg J, Lavefjord A, Sundström FTA, Bartels SL, Zetterqvist V, Wicksell RK, McCracken L, Goubert L

Journal of Pain Research 2025, 18:1545-1561

Published Date: 24 March 2025

Associations Between Circulating Inflammatory Cytokines and Neuropathic Pain: A Two-Sample Mendelian Randomization Study

Zheng Y, Wang H, Zhang H, Wu X, Zhou M, Denggui W

Journal of Pain Research 2025, 18:1525-1544

Published Date: 24 March 2025

The Causal Relationship Between Immune Cells and Neuropathic Pain: A Two-Sample Mendelian Randomization Study Based on Genome-Wide Association Analysis

Li W, Liu R

Journal of Pain Research 2025, 18:1515-1523

Published Date: 24 March 2025

Are Chronic Pain Fellowships Disguised as Acute Pain Fellowships Which Manage Chronic Pain? How to Recognize and Repair

Wahezi SE, Yener U, Day M, Staats PS, Gilligan C, Schatman ME, Pritzlaff SG

Journal of Pain Research 2025, 18:1511-1514

Published Date: 21 March 2025

The Addition of Intrathecal Clonidine to Reduce Medication-Related Side-Effects in Cancer Pain: A Retrospective Cohort Study

Bulat E, Chaturvedi R, Johnson P, Rakesh N, Gulati A

Journal of Pain Research 2025, 18:1503-1509

Published Date: 21 March 2025

Hyperalgesic Priming in the Transition From Acute to Chronic Pain: Focus on Different Models and the Molecular Mechanisms Involved

Zhang M, Li N, Zhao S, Feng X

Journal of Pain Research 2025, 18:1491-1501

Published Date: 21 March 2025

Exploring the Link Between Diabetes, Herpes Zoster, and Post-Herpetic Neuralgia: Insights From Mendelian Randomization

Yang X, Li D, Chen Y, Zhang X, Zhao Q

Journal of Pain Research 2025, 18:1479-1489

Published Date: 21 March 2025

Exploring Perceived Barriers and Facilitators for Implementing Acute Pain Clinical Trials: A Mixed-Methods Analysis of Ketamine Infusions for Sickle Cell Pain

Kenney MO, Limkakeng AT, Ochoa TN, Mathias JG, Knisely MR, Keefe F

Journal of Pain Research 2025, 18:1465-1478

Published Date: 20 March 2025

Non-Cognitive Behavioral Therapy Psychological Interventions May Not Make the Difference in Children and Adolescents With Chronic Pain

Perlman L, Malka N, Terry O, Nguyen A, Guimarães Ferreira Fonseca L, Ingelmo JI, Ingelmo P

Journal of Pain Research 2025, 18:1451-1464

Published Date: 20 March 2025

Original Research

Integrative/Acupuncture

Investigating the Analgesic Mechanisms of Acupuncture for Cancer Pain: Insights From Multimodal Bioelectrical Signal Analysis

Huang J, Zhao L, Xie Y, Wang C, Yang X, Huang H, Zhang D

Journal of Pain Research 2025, 18:1435-1450

Published Date: 20 March 2025

Analysis of Acupoint Selection Rules for Guasha Treatment of Primary Headaches Based on Data Mining [Response to Letter]

Zhang X, Huang X, Ni F, Yang D, Xu M

Journal of Pain Research 2025, 18:1433-1434

Published Date: 19 March 2025

Ultrasound-Guided vs Non-Guided Pharmacopuncture for Cervical Myofascial Pain Syndrome: A Multi-Center Prospective Comparative Study Protocol

Kim K, Song J, Chu H, Kwon R, Park S, Kwon J, Hong HJ, Lee Y, Kwon S, Kang K, Leem J, Kim CH

Journal of Pain Research 2025, 18:1417-1431

Published Date: 19 March 2025

High Pain Self-Efficacy Reduces the Use of Analgesics in the Early Postoperative Period After Total Knee Arthroplasty: A Retrospective Cohort Study

Sonobe T, Nikaido T, Sekiguchi M, Kaneuchi Y, Kikuchi T, Matsumoto Y

Journal of Pain Research 2025, 18:1407-1415

Published Date: 19 March 2025

Evaluating Large Language Models for Burning Mouth Syndrome Diagnosis

Suga T, Uehara O, Abiko Y, Toyofuku A

Journal of Pain Research 2025, 18:1387-1405

Published Date: 19 March 2025

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Detrimental Effects of Space Flight on the Lumbar Spine May Be Correlated to Baseline Degeneration: Insights From an Advanced MR Imaging Study

Bokhari R, Bisson DG, Fortin M, Vigouroux M, Cata JP, Hwang KP, Chen MM, Ceniza-Bordallo G, Ouellet JA, Ingelmo PM

Journal of Pain Research 2025, 18:1375-1385

Published Date: 19 March 2025

Pain Intensity and Pain Catastrophizing Among Patients with Chronic Pain: The Mediating Effect of Self-Efficacy

Li J, Cui Y, Jia Q, Ouyang A, Hua Y

Journal of Pain Research 2025, 18:1361-1373

Published Date: 19 March 2025

Association Between Spinopelvic Alignment and Reoperation Following Percutaneous Transforaminal Endoscopic Decompression: A Matched Case-Control Study

Ge Y, Wang A, Song H, Fan N, Zang L

Journal of Pain Research 2025, 18:1351-1360

Published Date: 18 March 2025

The Impact of Interscalene Brachial Plexus Block with Different Concentrations of Ropivacaine on Diaphragmatic Paralysis: A Randomized Controlled Study

Deng Y, Wang L, Zhang H, Xu Z, Jiang L, Zhou Y

Journal of Pain Research 2025, 18:1341-1349

Published Date: 17 March 2025

Review

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Spinal Cord Stimulation Explantation and Chronic Pain: A Systematic Review and Technology Recommendations

Wahezi SE, Yener U, Naeimi T, Lewis JB, Yerra S, Sgobba P, Ciftci HB, Vydyanathan A, Chiu E, Cherkalin D, Darji JY, Masterson R, Lee D, Jarusriwanna A, Palee S, Ortiz NR, Caparo M, Dayon E, Fontaine C, Bikson M, Schatman ME, Pritzlaff SG, Deer TR, Hunter CW

Journal of Pain Research 2025, 18:1327-1340

Published Date: 18 March 2025

Genicular Nerve Block as an Effective Treatment for Knee Pain: Addressing Variability and Enhancing Meta-Analysis Reliability [Letter]

Liu J, Wen C, Xu L

Journal of Pain Research 2025, 18:1325-1326

Published Date: 17 March 2025

Association Between Poor Pain Control and Sensory Impairment: A Cross-Sectional Study

Zeng J, Liao Z, Lin A, Zou Y, Chen Y, Liu Z, Luo H, Zhou Z

Journal of Pain Research 2025, 18:1313-1323

Published Date: 18 March 2025

Diagnostic Performance of Infrared Thermography, Quantitative Sudomotor Axonal Reflex Testing, and 3-Phase Bone Scintigraphy for Complex Regional Pain Syndrome Diagnosis: A Retrospective Observational Study

Noh C, Lee J, Choi HY, Park E, Shin YS, Hong B, Ko Y, Oh C, Lee SY

Journal of Pain Research 2025, 18:1305-1312

Published Date: 14 March 2025

A Cross-Sectional Study on Current Perioperative Pain Management and Nurses’ Pain Management Self-Efficacy in China’s Interventional Department

Zhang H, Meng Y, Xu X, Li Y, Li X, Hu H, Zheng L, Hu X

Journal of Pain Research 2025, 18:1291-1303

Published Date: 14 March 2025

Effect of Physical Activity on Chronic Widespread Pain: Insights From Meta-Analysis and Two-Sample Mendelian Randomization

Yao C, Zhang Y, Zhao SS, Ren J, Sun P, Kong L, Tao J, Li J, Fang M, Zhu Q

Journal of Pain Research 2025, 18:1275-1289

Published Date: 14 March 2025

Review

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

An Evidence-Based Consensus for the Use of Neurostimulation for the Treatment of Non-Surgical Low Back Pain: The NEURON Group

Deer TR, Pope JE, Petersen EA, Abdallah RT, Amirdelfan K, Azeem N, Bansal V, Barkoh K, Chapman KB, Denis DR, Dorsi MJ, Escobar A, Falowski SM, Garcia RA, Hagedorn JM, Heros RD, James WS, Kalia H, Lansford T, Malinowski MN, Manzi SM, Mehta P, Moghim RZ, Moore GA, Motivala SL, Navalgund YA, Patel RG, Pilitsis JG, Schatman ME, Shumsky PM, Strand NH, Tomycz ND, Yue JJ, Sayed D

Journal of Pain Research 2025, 18:1247-1274

Published Date: 14 March 2025

A Commentary on “Clinical Efficacy of Tuina Therapy for Acute Lumbar Sprain: A Bayesian Network Meta- Analysis Based on Randomized Controlled Trials” [Response to Letter]

Chen J, Li W, Li J

Journal of Pain Research 2025, 18:1243-1245

Published Date: 15 March 2025

Comment on “Use of Oral Celecoxib Preoperatively Reduces Risk of Delirium and Favors Functional Recovery in Elderly Patients with Femoral Neck Fracture: A Propensity Score-Matched Analysis” [Letter]

Fang K, Zhang S, Ding X

Journal of Pain Research 2025, 18:1241-1242

Published Date: 14 March 2025

Effect of Bilateral Erector Spinae Plane Block on the Gastrointestinal Function in Patients Undergoing Traumatic Lumbar Spine Fracture surgery: A Retrospective Study

Zhao M, Gao M, Zhang X, Zhou Q, Yu P, Liu C, Song X, Shan X, Dong J, Li Z, Wang Q

Journal of Pain Research 2025, 18:1231-1239

Published Date: 13 March 2025

Safety and Effectiveness of Electroacupuncture During Colon Endoscopic Submucosal Dissection: A Randomized Controlled Trial

Zhang J, Zhang H, Zheng J, Niu C, Zhu S, Hu H, Lu Y, Zhu M

Journal of Pain Research 2025, 18:1221-1229

Published Date: 13 March 2025

The Evaluation of Reference Values of Plasma and Effect-Site Concentrations of Propofol and Remifentanil During Extubation in Patients Who Had Hysteroscopy Procedures

Wei Y, Wang J, Xu Z, Ma R

Journal of Pain Research 2025, 18:1211-1219

Published Date: 12 March 2025

Analysis of Acupoint Selection Rules for Guasha Treatment of Primary Headaches Based on Data Mining [Letter]

Shi T, Liu Z

Journal of Pain Research 2025, 18:1209-1210

Published Date: 11 March 2025

Electroacupuncture Alleviates Neuropathic Pain and Negative Emotion in Mice by Regulating Gut Microbiota [Letter]

Wang R

Journal of Pain Research 2025, 18:1207-1208

Published Date: 11 March 2025

A Commentary on “Analysis of Factors Related to Throat Soreness After Painless Gastroscopy: A Single-Center Study” [Letter]

Fu W, Zhao J, Geng Y

Journal of Pain Research 2025, 18:1205-1206

Published Date: 11 March 2025

Fu’s Subcutaneous Needling Combined with Kinematic Acupuncture versus Electroacupuncture in the Treatment of Cervical Spondylotic Radiculopathy: A Randomized Controlled Trial

Lin Y, Hong W, Sui L, Jiang Q, Jiang G, Yan W, Xu N, Zhang R

Journal of Pain Research 2025, 18:1191-1204

Published Date: 12 March 2025

The Effectiveness of Acupuncture on Myofascial Trigger Points Versus Traditional Chinese Medicine Acupoints for Treating Plantar Fasciitis With Low Back Pain: A Study Protocol for a Randomised Clinical Trial [Letter]

Kalra R, Goyal K, Goyal M

Journal of Pain Research 2025, 18:1189-1190

Published Date: 11 March 2025

Local Structural Indices Changes During Different Periods of Postherpetic Neuralgia: A Graphical Study in Structural Covariance Networks

Xiong J, Gu L, Jiang X, Kuang H, Lv H, Li Z, Xie Y, Luo Q, Jiang J

Journal of Pain Research 2025, 18:1175-1187

Published Date: 11 March 2025

Addressing the Future of Pain Medicine Training: Redevelopment of Post-Doctoral Training as an Even More Imperative Standard in Latin America

Diez-Tafur R, Silva-Ortiz VM, Guerrero-Nope C, Vargas-Silva JF, Lobo C, Assis FD, Schatman ME, Robinson CL, Diwan S, Plancarte-Sanchez R

Journal of Pain Research 2025, 18:1173-1174

Published Date: 11 March 2025

Attention Deficits in Migraine: Mismatch Negativity and P3a in an Event-Related Potential Study

Nie P, Wang T, Wu Q, Chen W, Shen F, Huang L, Dong X

Journal of Pain Research 2025, 18:1161-1171

Published Date: 10 March 2025

Effect of Adding Nalbuphine to Ropivacaine on Postoperative Analgesia of Erector Spinae Plane Block [Letter]

Wang DF, Guo YH, Xue FS

Journal of Pain Research 2025, 18:1159-1160

Published Date: 11 March 2025

Evolution of the Quality of Life of Long-Term Fibromyalgia Users of Millimeter Wave-Based Neuromodulation: A Real-World Retrospective Study

Minier L, Zanini P, Chipon E, Gonon-Demoulian R, Treillet E, Crouzier D

Journal of Pain Research 2025, 18:1143-1157

Published Date: 10 March 2025

Original Research

Effectiveness of Electromagnetic Field Therapy in Mechanical Low Back Pain: A Randomized Controlled Trial

Koura GMR, Elshiwi AMF, Alshahrani MS, Elimy DA, Alshahrani RAN, Alfaya FF, Alshehri SHS, Hadi AA, Alshehri MA, Alnakhli HH, Ahmad F, Ahmad I

Journal of Pain Research 2025, 18:1131-1142

Published Date: 8 March 2025

Electroacupuncture Inhibits NLRP3-Mediated Microglial Pyroptosis to Ameliorate Chronic Neuropathic Pain in Rats

Kui W, Li Y, Gu Z, Xie L, Huang A, Kong S, Song L, Li L, Yu J, Xue CC, Wang K

Journal of Pain Research 2025, 18:1115-1129

Published Date: 7 March 2025

The Effectiveness of Acupuncture on Myofascial Trigger Points versus Traditional Chinese Medicine Acupoints for Treating Plantar Fasciitis with Low Back Pain: A Study Protocol for a Randomised Clinical Trial [Letter]

Ghosh S, Maurya S, Pattnaik S

Journal of Pain Research 2025, 18:1111-1113

Published Date: 7 March 2025

The Effectiveness of Acupuncture on Myofascial Trigger Points Versus Traditional Chinese Medicine Acupoints for Treating Plantar Fasciitis With Low Back Pain: A Study Protocol for a Randomised Clinical Trial [Letter]

Wang J, Qi W, Tian J

Journal of Pain Research 2025, 18:1109-1110

Published Date: 8 March 2025

Cortical Activation and Functional Connectivity Response to Different Interactive Modes of Virtual Reality (VR)-Induced Analgesia: A Prospective Functional Near-Infrared Spectroscopy (fNIRS) Study