Piotrowski A, Schmidt A, Kufeld N, Kersting C, Bencheva V, Wiese B, Bahrs O, Hunger-Schoppe C, Maas M, Preuss J, Just JM, Weckbecker K, Thürmann P, Mortsiefer A

Journal of Pain Research 2026, 19:564795

Published Date: 9 April 2026

Original Research

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Spinal Cord Stimulators’ Displacement: Systematic Review and Single-Institution Case Series with Anchoring Technique

Mariadas R, Pan E, Boesel TW, Di Ieva A

Journal of Pain Research 2026, 19:547502

Published Date: 9 April 2026

Letter

Integrative/Acupuncture

The Effectiveness of Fu’s Subcutaneous Needling for Residual Pain After Percutaneous Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures: A Randomized Clinical Trial Protocol [Letter]

Kang J, Li S, Mao Y

Journal of Pain Research 2026, 19:614672

Published Date: 9 April 2026

Letter

Integrative/Acupuncture

Transcriptome Changes of ACC in IBS Rats Induced by Electroacupuncture: Exploration of Mechanism and Clinical Significance [Letter]

Zhao J, Ye X, Li X

Journal of Pain Research 2026, 19:611207

Published Date: 9 April 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Burden and Risk Factors of Neck Pain in China: A Dual-Database Study of GBD 2021 Population-Level Macro-Trends and CHARLS Individual-Level Prospective Cohort Analyses

Zhao Z, Liu J, Li S, Liu X, Xu S, Lu B, Meng X

Journal of Pain Research 2026, 19:585442

Published Date: 8 April 2026

Review

Pediatric Pain

A Comprehensive Evidence-Based Review of Non-Pharmaceutical Interventions for Neonatal Pain

Cai Y, Sun S, Chen C

Journal of Pain Research 2026, 19:571070

Published Date: 8 April 2026

Original Research

Acute Pain and Perioperative Care

Association Between Long-Term ACEI/ARB Use and Postoperative Pain in Hypertensive Patients: A Retrospective Cohort Study and Genetic Validation

Li X, Che L, Shen L

Journal of Pain Research 2026, 19:549864

Published Date: 8 April 2026

Letter

Behavioral Approaches to Pain

Comparison of the Efficacy of Different Traditional Chinese Exercises in the Treatment of Chronic Non-Specific Low Back Pain: A Bayesian Network Meta-Analysis [Letter]

Jiang Y, Li L, Fang J

Journal of Pain Research 2026, 19:612219

Published Date: 8 April 2026

Clinical Trial Report

Acute Pain and Perioperative Care

Monocyte Transmigration Involves in Remifentanil Induced Mechanical Hyperalgesia in Animal Models and a Randomized Controlled Clinical Trial

Zhang R, Ye Z, Chen Q, Zhu Y, Wang Y, He H, Li J, Hu Y, Gan X

Journal of Pain Research 2026, 19:545720

Published Date: 8 April 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Ipsilateral Knee Pain After Total Hip Arthroplasty: Pathogenesis and Intervention Strategies—A Narrative Review

Lin X, Wei Z, Wang Z, Yin G, Cheng Q, Li S

Journal of Pain Research 2026, 19:590938

Published Date: 7 April 2026

Review

Acute Pain and Perioperative Care

Effect of Liposomal Bupivacaine in Peripheral Nerve Block Following Thoracoscopic Lung Surgery: A Systematic Review and Meta-Analysis

Hu J, Zhang K, Ma Z, Ren D, Yan W

Journal of Pain Research 2026, 19:596114

Published Date: 7 April 2026

Letter

Acute Pain and Perioperative Care

Methodological Considerations in Combined Pudendal Nerve Block and Wrist-Ankle Acupuncture for Postoperative Analgesia After Perianal Abscess Surgery [Letter]

Lu CW, Chang KC

Journal of Pain Research 2026, 19:612825

Published Date: 7 April 2026

Response to Letter

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

The Efficacy and Safety of Ultrasound-Guided Nerve Block in the Treatment of Cervical Spondylotic Radiculopathy: A Systematic Review and Meta-Analysis [Response to Letter]

Deng M, Tang N, Wu D, Kuang J

Journal of Pain Research 2026, 19:608993

Published Date: 7 April 2026

Letter

Integrative/Acupuncture

The Effectiveness of Fu’s Subcutaneous Needling for Residual Pain After Percutaneous Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures: A Randomized Clinical Trial Protocol [Letter]

Chen LQ, Ma RJ

Journal of Pain Research 2026, 19:611825

Published Date: 7 April 2026

Review

Pre-Clinical/Scientific

A Comprehensive Review of the Clinical Utility and Reliability of a Quantitative Electrical Stimulation Device for Objective Pain Assessment

Kato K

Journal of Pain Research 2026, 19:585386

Published Date: 3 April 2026

Review

Pharmacology

Pharmacological Pain Management in Adults with Venous Ulceration: A Systematic Review

Saghdaoui LB, Lampridou S, Baldo L, Onida S, Hohenschurz-Schmidt D, Chumbley GM, Atkin L

Journal of Pain Research 2026, 19:588661

Published Date: 1 April 2026

Original Research

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Quantum Mechanical Mechanisms in the Therapeutic Effects of Spinal Cord Stimulation to Treat Chronic Neuropathic Pain: A Quantum Computational Model

Abdallat M, Qaswal AB, Quzli A, Hassan M, Alkhatib S, Khraim Y, Alkhateeb G, Alsmadi O, Abdulqader Z, Shitawi J, Miqdadi HR, Nuseir M, Alzeerelhouseini HIA, Hanif S, Essa O, Yousef D, Alsoub F, Okour M, Alzubaidi A, Alsahli O, El-Isa H, Alsaddi H, Al-Rashdan MO

Journal of Pain Research 2026, 19:566042

Published Date: 1 April 2026

Editorial

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

When Regional Anesthesia is Mistaken for Pain Medicine: The Importance of Etiology-Driven Interventional Pain Management

Lo Bianco G, Demartini L, Mercieri M, Schatman ME

Journal of Pain Research 2026, 19:603998

Published Date: 1 April 2026

Original Research

Behavioral Approaches to Pain

Negative Emotional Influences on Pressure Pain Thresholds: Findings from a Quasi-Randomized Controlled Trial

Gunnarsson H, Safipour J, Lindqvist G

Journal of Pain Research 2026, 19:585219

Published Date: 1 April 2026

Review

Acute Pain and Perioperative Care

The Bidirectional Relationship Between Perioperative Sleep Deprivation and Postoperative Pain — Mechanisms and Clinical Implications: A Narrative Review

Liu J, Liang Z, Wang H, Chen S, Xie Y, Xing F, Wang Z, Yuan J

Journal of Pain Research 2026, 19:590177

Published Date: 31 March 2026

Original Research

Integrative/Acupuncture

Data Mining of Acupuncture Prescriptions for Lateral Epicondylitis: A Literature-Based Analysis of Acupoint Patterns and Parameters

Xu Y, Chen M, Dong Y, Wang F, Lai Q, Ye Y, Huang J, Xu Y, Shi M, Zhan Q

Journal of Pain Research 2026, 19:583466

Published Date: 31 March 2026

Review

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Spinal Cord Stimulation for Pain Management Following Spinal Cord Injury: A Systematic Review

Gallacher DM, Suarez M, Jevotovsky DS, Oehlermarx W, Azad TD, Dovlatyan R, Chopra H, Broachwala M, AlFarra T, Petersen EA, Patel KV, Orhurhu V, Castellanos J

Journal of Pain Research 2026, 19:573333

Published Date: 30 March 2026

Clinical Trial Report

Acute Pain and Perioperative Care

Determining ED50 of Nalbuphine for Intraoperative Analgesia in Elderly Patients Undergoing Percutaneous Kyphoplasty: A Prospective, Double-Blind, Single-Center, Dose-Finding Study

Zhao P, Song X, Liu Y, Luo Y, Cui Z, Guo Y, Wang X, Yang J, Zhou H

Journal of Pain Research 2026, 19:594008

Published Date: 30 March 2026

Original Research

Acute Pain and Perioperative Care

Risk Factors and Nomogram-Based Risk Stratification for Moderate-to-Severe Acute Postsurgical Pain After Open Lumbar Fusion: A Prospective Cohort Study

Wang W, Lv J, Zhao W, Shi X, Yu D, Chen J

Journal of Pain Research 2026, 19:588610

Published Date: 30 March 2026

Original Research

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Machine Learning Approach to Predict Postoperative Pain and Opioid Usage in Elective Primary Spine Surgery: A Retrospective Study

Saksenberg DL, Lee RY, Vaidya S, Yuan A, Jeong SJ, Lockwood N, Li J, Russo GS

Journal of Pain Research 2026, 19:596384

Published Date: 27 March 2026

Original Research

Acute Pain and Perioperative Care

Utility of Peripheral Nerve Block in Lower Extremity Amputation

Onyewu SC, Yanez D, Nnamdi J, Onyewu MC, Effraim PR

Journal of Pain Research 2026, 19:588924

Published Date: 27 March 2026

Letter

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

A Cross-Sectional Survey on Musculoskeletal Pain Among Professional and Non-Professional Gamers in Saudi Arabia: Associations with Gaming Genre, Duration, and Ergonomic Factors [Letter]

Sengupta S, Dangmei G

Journal of Pain Research 2026, 19:608624

Published Date: 27 March 2026

Original Research

Acute Pain and Perioperative Care

Establishing a Predictive Model for Acute Postoperative Pain at PACU Awakening Based on Preoperative Hypoalbuminemia and Anemia: Clinical Implications for Perioperative Nursing

Tu Y, Du W, Zhang X, Chen Y, Zhou B, Sun C, Xu M

Journal of Pain Research 2026, 19:583667

Published Date: 27 March 2026

Review

Pediatric Pain

Application of Intelligent Neonatal Pain Assessment Tools Based on Multimodal Data Fusion: A Systematic Review

Zhou Q, Huang X, Lv Y, Xiao Z, Luo S, Wang Z, Li Y, Li Y, Chen Q, Yu Z, Zhou Q

Journal of Pain Research 2026, 19:578721

Published Date: 27 March 2026

Review

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Comparative Efficacy of Regional Analgesic Interventions in Open versus Laparoscopic Hepatic Surgery: A Network Meta-Analysis

Song M, Hu H, Jiang L, Wei J

Journal of Pain Research 2026, 19:577411

Published Date: 27 March 2026

Response to Letter

Opioids and Substance Abuse

Beyond Methodological Considerations: Clinical Implications of Real-World Evidence from the CARE Study [Response to Letter]

Überall MA, Müller-Schwefe PCG, Küster MA, Müller-Schwefe GHH

Journal of Pain Research 2026, 19:611585

Published Date: 27 March 2026

Original Research

Acute Pain and Perioperative Care

Comparison of the Analgesic Effect and Recovery Quality Between Erector Spinae Plane Block and Quadratus Lumborum Plane Block in Laparoscopic Cholecystectomy: A Retrospective Study

Zhu K, Qian K, Zhang H, Zhai W, Zhang Y, Yang J

Journal of Pain Research 2026, 19:571650

Published Date: 27 March 2026

Original Research

Pre-Clinical/Scientific

Exploring the Influence of Testosterone on Pain Perception and Modulation Among Men with Low and Normal Testosterone Concentrations

Vincenot M, Bordeleau M, le Blanc F, Pagé C, Gaumond I, Léonard G, Marchand S

Journal of Pain Research 2026, 19:571741

Published Date: 27 March 2026

Study Protocol

Acute Pain and Perioperative Care

Efficacy of Nonpharmacological Interventions in Acute Postoperative Pain of Patients with Lung Cancer Undergoing Video-Assisted Thoracoscopic Surgery: A Protocol for Systematic Review and Network Meta-Analysis

Shen J, Tian H, Qi H

Journal of Pain Research 2026, 19:573012

Published Date: 27 March 2026

Letter

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Multi-Institutional Pragmatic Randomized Controlled Trial to Evaluate the Effectiveness of Manual Maintenance Therapy for Chronic Bothersome Neck Pain [Letter]

Srivastava A, Mishra B, Pattnaik S

Journal of Pain Research 2026, 19:610421

Published Date: 27 March 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Central Sensitization and Nociplastic Pain: Shared Mechanisms in Fibromyalgia, Osteoarthritis, and Inflammatory Arthritis

Hladkykh FV, Liadova TI, Matvieienko MS, Komorovsky R, Smiyan S, Student V

Journal of Pain Research 2026, 19:571311

Published Date: 26 March 2026

Letter

Opioids and Substance Abuse

Refining Cannabinoid Ratios for Geriatric Pain: Methodological and Clinical Reflections on the CARE Study [Letter]

Qiang D, Zheng C, Xu Y

Journal of Pain Research 2026, 19:608085

Published Date: 25 March 2026

Original Research

Acute Pain and Perioperative Care

Optimizing Postoperative Analgesia After Perianal Abscess Surgery Using Ultrasound-Guided Pudendal Nerve Block Combined with Wrist-Ankle Acupuncture: A Randomized Controlled Trial

Zhang C, Yang J, Feng L, Zhao X, Tang P

Journal of Pain Research 2026, 19:592180

Published Date: 25 March 2026

Original Research

Acute Pain and Perioperative Care

Progressive Early Mobilization and Its Impact on Pain and Function After Lumbar Vertebral Compression Fracture: A Retrospective Study Based on the Oswestry Disability Index

Liu X, Huang Y, Zhang Y

Journal of Pain Research 2026, 19:579740

Published Date: 25 March 2026

Original Research

Pre-Clinical/Scientific

Experimental Investigation of Fentanyl Analgesic Potency and Its Relationship with Endogenous Adrenaline Levels in Rats

Ates I, Isik B, Sezgin ET, Altuner D, Coban TA, Suleyman H

Journal of Pain Research 2026, 19:582322

Published Date: 25 March 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Hyperbaric Oxygen Therapy in Managing Chronic Pain Syndromes – A Systematic Review

Leys AM, Hans GH, Saldien V, Wildemeersch D

Journal of Pain Research 2026, 19:597243

Published Date: 24 March 2026

Original Research

Behavioral Approaches to Pain

Effects of Music Intervention on Pain, Mood, Sleep, and Heart Rate Variability in Patients with Chronic Pain: A Randomized Controlled Trial

Wang B, Yu F, Ma Y, Zhao H, Wu W, Zheng Y

Journal of Pain Research 2026, 19:584043

Published Date: 23 March 2026

Original Research

Behavioral Approaches to Pain

Association Between Pain Subtypes and Cognitive Impairment in Parkinson’s Disease

Gao L, Li Z, Cai L, Xu W, Liu Y

Journal of Pain Research 2026, 19:559348

Published Date: 23 March 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Trigeminal Nerve Blocks for Medically Intractable Painful Trigeminal Neuropathy

Chen YC, Cheng HT

Journal of Pain Research 2026, 19:574753

Published Date: 23 March 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Optimizing Osteoarthritis Management – Therapeutic Efficacy and Evaluation of Intra-Articular Triamcinolone Acetonide Injection

Wan Y, Kong L, Ning R

Journal of Pain Research 2026, 19:571167

Published Date: 23 March 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Global Co-Burden and Risk Factors of Low Back Pain and Osteoarthritis: Analysis of Global Burden of Disease 2021 Data Based on Machine Learning and SHAP

Li X, Shuid AN, Mohd Miswan MF, Cao D, Zhang X, Mao P, Tian Y, Yuan H

Journal of Pain Research 2026, 19:590969

Published Date: 21 March 2026

Original Research

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Predictive Value of Epidural Gas Spread Pattern Following Transforaminal Ozone Injection for Clinical Outcomes in Cervical Radiculopathy: A Prospective Cohort Study

Yang M, Qiong X, Xu X, Abdullah Al-Goshae HA

Journal of Pain Research 2026, 19:591176

Published Date: 21 March 2026

Review

Behavioral Approaches to Pain

Body Image and Body Awareness Interventions in Chronic Pain: A Systematic Review of Effects on Pain-Related Variables and Emotional Distress

Navarro-Moreno V, Zamora Á, Herrero R, Miragall M, Parola G, Saccone V, Baños RM

Journal of Pain Research 2026, 19:579981

Published Date: 20 March 2026

Response to Letter

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Effectiveness of Jaw Exercises Applied in Addition to Cervical Stabilization Exercises in Individuals with Chronic Neck Pain: A Randomized Controlled Trial [Response to Letter]

Canli M, Özüdoğru A, Alkan H, Cigdem-Karacay B

Journal of Pain Research 2026, 19:608739

Published Date: 20 March 2026

Study Protocol

Integrative/Acupuncture

The Effectiveness of Fu’s Subcutaneous Needling for Residual Pain After Percutaneous Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures: A Randomized Clinical Trial Protocol

Wang Q, Ren Z, Wang B, Du J, Li X, Mou J

Journal of Pain Research 2026, 19:597553

Published Date: 20 March 2026

Original Research

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Multi-Patient Analysis of Steroid-Induced Hyperglycemia in Diabetic Patients Using Continuous Glucose Monitoring

Birthi P, Pattabiraman M, Ramaswamy A, Kumar M, Agrawal A, Dua A, Nalamachu SR, Chandra S

Journal of Pain Research 2026, 19:569171

Published Date: 20 March 2026

Original Research

Acute Pain and Perioperative Care

Emergency Department Presentations for Jellyfish Stings in Southern China: A Cross-Sectional Analysis of Pain Severity and Treatment Timing

Li X, Wang H, Guo X, Huo C, Jiang M, Zhang J

Journal of Pain Research 2026, 19:576516

Published Date: 19 March 2026

Letter

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Effectiveness of Jaw Exercises Applied in Addition to Cervical Stabilization Exercises in Individuals with Chronic Neck Pain: A Randomized Controlled Trial [Letter]

Das N, Pal S

Journal of Pain Research 2026, 19:607446

Published Date: 18 March 2026

Study Protocol

Integrative/Acupuncture

Effect of Electroacupuncture on Postoperative Urinary Retention After Radical Hysterectomy for Cervical Cancer: Study Protocol for A Randomized Controlled Trial

Lu C, Chen N, Sun H, Wang C, Zhao L, Bao W, Deng D, Wang P, Li X

Journal of Pain Research 2026, 19:598960

Published Date: 18 March 2026

Original Research

Ethics/Policy

Validation of the Kuopio Questionnaire on Pain Management Attitudes Among Healthcare Personnel in a Finnish Teaching Hospital

Paunonen P, Tyynelä-Korhonen K, Nuutinen R, Haatainen KM, Kervinen M, Wüstefeld M, Pöyhiä R, Lamminmäki A

Journal of Pain Research 2026, 19:532085

Published Date: 18 March 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Psychometric Properties of a Smartphone Application for Measuring Shoulder Active Range of Motion in Individuals with and without Shoulder Pain and Mobility Deficits

Aafreen A, Khan AR, Ahmad A, Alshehre YM, Alshehri MM, Shaphe MA, Aldhahi MI

Journal of Pain Research 2026, 19:581403

Published Date: 18 March 2026

Study Protocol

Integrative/Acupuncture

Multi-Institutional Pragmatic Randomized Controlled Trial to Evaluate the Effectiveness of Manual Maintenance Therapy for Chronic Bothersome Neck Pain

Yun JM, Kim JY, Lee SH, Lee YJ, Heo I, Shin WC, Cho JH, Seo BK, Ha IH

Journal of Pain Research 2026, 19:577619

Published Date: 18 March 2026

Letter

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

The Efficacy and Safety of Ultrasound-Guided Nerve Block in the Treatment of Cervical Spondylotic Radiculopathy: A Systematic Review and Meta-Analysis [Letter]

Rai A, Chandan SK

Journal of Pain Research 2026, 19:607166

Published Date: 17 March 2026

Original Research

Cancer Pain and Palliative Care

Exploring Acceptance of Pain Management Strategies in Oncology: A Single-Center Cross-Sectional Survey

Chiriac VF, Moșoiu DV

Journal of Pain Research 2026, 19:576823

Published Date: 17 March 2026

Study Protocol

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Efficacy and Central Mechanism of Shexiang Zhuifeng Analgesic Plaster Combined with Transcranial Direct Current Stimulation in the Treatment of Knee Osteoarthritis: Study Protocol for a Randomized Controlled Trial

Liu Q, Yang K, Shen Z, Zi T, Bian J, Song Y, Jiang L

Journal of Pain Research 2026, 19:584335

Published Date: 16 March 2026

Original Research

Integrative/Acupuncture

Core Acupoint Prescription Patterns for Primary Dysmenorrhea: Data Mining and Network-Based Analysis

Yang T, Guo W, Deng C, Zhang L

Journal of Pain Research 2026, 19:579686

Published Date: 16 March 2026

Study Protocol

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

A Comparative Analysis of Ultrasound versus Fluoroscopy-Guided Transforaminal Endoscopic Lumbar Discectomy: Protocol for a Randomized Clinical Trial Targeting Lumbar Disc Herniation

Shang C, Lv Z

Journal of Pain Research 2026, 19:572811

Published Date: 16 March 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Biopsychosocial Factors Affecting Disability in Individuals with Chronic Nonspecific Low Back Pain: A Cross-Sectional Study

Canli İ, Özüdoğru A

Journal of Pain Research 2026, 19:590191

Published Date: 13 March 2026

Original Research

Acute Pain and Perioperative Care

The Analgesic Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block for Laparoscopic Living Donor Hepatectomy: A Randomized Controlled Study

Liu S, Yang Y, Wei L, Zhang L, Li X, Hao X, Cui L

Journal of Pain Research 2026, 19:567829

Published Date: 13 March 2026

Clinical Trial Report

Acute Pain and Perioperative Care

Effects of Transverse Abdominis Plane Block with Ropivacaine-Hydromorphone versus. Ropivacaine in Cesarean Section: A Randomized Controlled Trial

Zhang J, Zhang D, Wang Y, Li W, Tu H

Journal of Pain Research 2026, 19:592353

Published Date: 13 March 2026

Clinical Trial Report

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Tuina Alleviates Pain Associated with Lumbar Disc Herniation by Regulating Functional Connectivity Between Inferior Frontal Triangularis and Multiple Brain Networks: A Randomized Controlled fMRI Study

Jiang C, Zhang H, Wu X, Huang L, Zhou X, Lin J, Chen L, Huang H, Chen S, Zhang J, Lin Z

Journal of Pain Research 2026, 19:592723

Published Date: 12 March 2026

Letter

Pre-Clinical/Scientific

Metabolomics Analysis Reveals Gut Microbiota-Associated Sakuranin Modulates Endometrial Stem Cell Differentiation and Inflammation to Alleviate Pain in Endometriosis [Letter]

Liu Y

Journal of Pain Research 2026, 19:607364

Published Date: 12 March 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Novel Insights into the Management of Painful Trigeminal Neuropathy: Targeting Peripheral and Central Pathomechanisms

Chen YC, Cheng HT

Journal of Pain Research 2026, 19:575216

Published Date: 11 March 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

The Impact of Population Aging on Ergonomic-Related Low Back Pain Across Regions with Different Development Levels

Yang X, Li B, Wen M, Guo X, Peng H

Journal of Pain Research 2026, 19:575648

Published Date: 11 March 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Practice Patterns of Physicians Who Perform Lumbar Interlaminar Epidural Steroid Injections: A Technical Survey

Hasoon J, Yost C, Leung A, Apai C, Simopoulos TT, Lo Bianco G, Viswanath O, Gill J, Robinson CL

Journal of Pain Research 2026, 19:582178

Published Date: 11 March 2026

Original Research

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Evaluate the Analgesic Effect and Functional Recovery of Designed Novel 3D CT-Guided Intelligent-Assisted Radiofrequency Nonpharmacological Ablation for Suprascapular Nerve Entrapment: A Retrospective Study

Fan J, Guang Z, Yang W, Li Y, Yang Q, Feng W

Journal of Pain Research 2026, 19:580963

Published Date: 10 March 2026

Review

Surgical Approaches to Pain

Efficacy of Erector Spinae Plane Block in Lumbar Fusion Surgery: A Systematic Review and Meta-Analysis on Opioid-Sparing and Postoperative Pain Outcomes

Ye J, Wu J, Zhou Y, Mao C

Journal of Pain Research 2026, 19:573516

Published Date: 10 March 2026

Study Protocol

Integrative/Acupuncture

Proteomics and Metabolomics-Based Investigation of Local Microenvironmental Changes in Sensitized Acupoint Compared to Non-Sensitized Point Among Patients with Chronic Atrophic Gastritis: A Cross-Sectional Study Protocol

Yang G, Liu CZ, Ren CH, Shi GX, Yang JW, Wang YG, Yang NN

Journal of Pain Research 2026, 19:580054

Published Date: 10 March 2026

Letter

Acute Pain and Perioperative Care

Advancing the Prevention of Postherpetic Neuralgia: Methodological and Clinical Considerations for the TPI Study Protocol [Letter]

Mao Y, Han J, Lu K

Journal of Pain Research 2026, 19:606043

Published Date: 9 March 2026

Original Research

Opioids and Substance Abuse

CARE – A Retrospective, Dual-Cohort, 24-Week Real-World Study from the German Pain e-Registry on the Effectiveness and Safety of CBD-Dominant Oral Cannabis Extracts versus THC/Dronabinol in Older Patients with Chronic Pain

Überall MA, Müller-Schwefe PCG, Küster MA, Müller-Schwefe GH

Journal of Pain Research 2026, 19:551457

Published Date: 7 March 2026

Clinical Trial Report

Surgical Approaches to Pain

Hydromorphone is Noninferior to Dexamethasone as an Adjuvant to Ropivacaine for Transversus Abdominis Plane Block After Laparoscopic Colorectal Cancer Surgery: A Randomized, Double-Blind Trial

Zhao L, Wang Y, Guo Q, An Q, Wu M, Fan C, Guo Z

Journal of Pain Research 2026, 19:581520

Published Date: 5 March 2026

Review

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

The Efficacy and Safety of Ultrasound-Guided Nerve Block in the Treatment of Cervical Spondylotic Radiculopathy: A Systematic Review and Meta-Analysis

Deng M, Wu D, Tang N, Kuang J

Journal of Pain Research 2026, 19:573563

Published Date: 4 March 2026

Review

Integrative/Acupuncture

Data Mining-Based Analysis of Acupoint Selection Patterns in Acupuncture Treatment for Lumbar Disc Herniation

Zheng Z, Feng J, Li Y, Li X, Su C, Bai P

Journal of Pain Research 2026, 19:576514

Published Date: 4 March 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Safety and Efficacy of Tunneled Sciatic Nerve Catheters in Combat Injuries: Ukrainian Experience

Voloshchuk R, Halushko A

Journal of Pain Research 2026, 19:578284

Published Date: 3 March 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Remote Therapeutic Monitoring in Musculoskeletal Pain Medicine: A Systematic Review and Comparison with Remote Physiologic Monitoring

Zhang K, Schatman ME, Hascalovici J

Journal of Pain Research 2026, 19:588752

Published Date: 3 March 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Myoelectric and Progressive Motor Training for Phantom Limb Pain in People with Amputations During War: A Feasibility Report

Ksenchyna K, Huk Y, Kristoffersen MB, Buist M, McGowan E, Limakatso K, Kovalenko S, Dmytriiev D, Ortiz-Catalan M

Journal of Pain Research 2026, 19:578370

Published Date: 3 March 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Postoperative Functional Mobility and Quality of Life in Patients with Anteromedial Osteoarthritis of the Knee Treated with MB-UKA versus TKA

Li SM, Liang BR, Xiao K, Fan CY, Li D, Han FF, Chen J

Journal of Pain Research 2026, 19:564539

Published Date: 3 March 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Dissecting the Genetic Basis of Low Back Pain Independent of BMI Through Genomic Structural Equation Modeling

Huo L, Tan L, Wang F, Sun J, Niu Y, Jiang Y, Wu M, Shi J, Hao Y, Wang J, Huang S, Chen Z

Journal of Pain Research 2026, 19:581757

Published Date: 3 March 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Comparison of the Efficacy of Different Traditional Chinese Exercises in the Treatment of Chronic Non-Specific Low Back Pain: A Bayesian Network Meta-Analysis

Huang M, Liu H, Zeng L, Chen J

Journal of Pain Research 2026, 19:590557

Published Date: 3 March 2026

Study Protocol

Pharmacology

The Efficacy and Safety of Crisugabalin (HSK16149) in Fibromyalgia Patients: Protocol for a Prospective Randomized Open Blinded-Endpoint (PROBE) Study

Liu M, Li R, Zhou H, Xie Z, He Y, Ren F, Feng X, Fan B, Li S, Luo F, Zhang D

Journal of Pain Research 2026, 19:580694

Published Date: 3 March 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Linear Association of Derivatives of Triglyceride-Glucose Index with Incident Lower Limb Joint Pain in Middle-Aged and Older Chinese Adults: A Prospective Cohort Study

Xue M, Chen X, Deng Q, Ye Y, Xun T, Liu Y, Yang X

Journal of Pain Research 2026, 19:577438

Published Date: 28 February 2026

Review

Acute Pain and Perioperative Care

Best Evidence Summary for Postoperative Pain Management in Adult ICU Patients

An J, An X, Li B

Journal of Pain Research 2026, 19:576541

Published Date: 28 February 2026

Review

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Pain as Lived Experience: Philosophical Perspectives in Pain Medicine – A Narrative Review

Shin DA, Chang MC

Journal of Pain Research 2026, 19:577740

Published Date: 26 February 2026

Letter

Acute Pain and Perioperative Care

Compare the Effects of Transversalis Fascia Plane Block versus Intravenous Lidocaine Infusion on the Quality of Early Postoperative Recovery in Patients Undergoing Gynecologic Laparoscopic Surgery [Letter]

Qi X

Journal of Pain Research 2026, 19:599807

Published Date: 26 February 2026

Review

Acute Pain and Perioperative Care

Effect of Perineural Dexamethasone on the Duration of Analgesia in Paravertebral Block: A Meta-Analysis

Wu T, Chen X, Xu J, Zhang X, Miao S

Journal of Pain Research 2026, 19:572398

Published Date: 26 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Comparative Efficacy of Scalene versus Scapular Approach for Ultrasound-Guided Corticosteroid Hydrodissection in Dorsal Scapular Nerve Entrapment: A Randomized Controlled Trial

Elawamy AM, Lam KHS, Allam AES, Abo Elfadl GM, Moshrif A, Ahmad AA, Mohamed EF, AbdelRady MM, Shabaan N, Ghoraba Y, Yoon Y, Hassanien M

Journal of Pain Research 2026, 19:576439

Published Date: 26 February 2026

Study Protocol

Opioids and Substance Abuse

Effect of Intrathecal Hydromorphone on the Duration and Efficacy of Postoperative Analgesia in Patients Undergoing Benign Anorectal Surgery: Protocol for a Randomized, Double-Blind, Controlled Trial

Cao Y, Zhou Y, Zhou D, Xiong C, Fu L, Chen X, Zhang X

Journal of Pain Research 2026, 19:569284

Published Date: 26 February 2026

Original Research

Pre-Clinical/Scientific

Differences in Experimental Pain Sensitivity Between Non-African and African American Healthy Individuals and Patients with Painful Chronic Pancreatitis

Phillips AE, Faghih M, Ramsey ML, Han S, Hart PA, Afghani E, Bick BL, Easler JJ, Yadav D, Wilcox CM, Olesen SS, Drewes AM, Singh VK

Journal of Pain Research 2026, 19:562097

Published Date: 25 February 2026

Review

Integrative/Acupuncture

Efficacy of Governor Vessel–Based Acupuncture, Alone or in Combination with Other Therapies, for Acute Lumbar Disc Herniation: A Systematic Review and Meta-Analysis

Yang S, Guo Q, Zhang M, Zhang W, Ren S

Journal of Pain Research 2026, 19:586965

Published Date: 25 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

A Cross-Sectional Survey on Musculoskeletal Pain Among Professional and Non-Professional Gamers in Saudi Arabia: Associations with Gaming Genre, Duration, and Ergonomic Factors

Alqabbani S, Alhussaini RF, Alsaedan SA, Alfaqi MK, Almudaifer RI, Zain Aldeen NM, Alsaeed HA, Algabbani MF, Alahmari W, Almuwais A, Alotaibi M

Journal of Pain Research 2026, 19:557124

Published Date: 24 February 2026

Original Research

Acute Pain and Perioperative Care

Effect of the Evidence-Based and Multidisciplinary Pain Management Program in Patients After Laparoscopic Hepatectomy: A Quasi-Experimental Study

Song X, Liu Y, Zou J, Zhang D, Bai T, Han Z, Wang Y

Journal of Pain Research 2026, 19:582027

Published Date: 24 February 2026

Original Research

Acute Pain and Perioperative Care

Intertransverse Process Block versus Erector Spinae Plane Block as Adjuncts to an Interpectoral Block for Breast Cancer Surgery: A Randomized Controlled Trial

Samerchua A, Ditsatham C, Supphapipat K, Konkarn N, Leurcharusmee P, Wongmaneerung P, Owaphakorn T, Prapussarakul K, Jinadech T, Wanvoharn M

Journal of Pain Research 2026, 19:579089

Published Date: 24 February 2026

Study Protocol

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Cervical Rotation-Traction Manipulation of Different Treatment Frequency in Cervical Radiculopathy: Study Protocol for a Randomized Controlled Trial

Feng T, Wang X, Sun K, Yin H, Liu A, Li Z, Li J, Zhu L, Wei X

Journal of Pain Research 2026, 19:547284

Published Date: 24 February 2026

Review

Integrative/Acupuncture

A Network Meta-Analysis Comparing the Efficacy Differences of Different Acupuncture and Sodium Hyaluronate Eye Drops in the Treatment of Dry Eye Disease

Yan X, Hu J, Chen Y, Lei S, Chen J, Qin M

Journal of Pain Research 2026, 19:577237

Published Date: 23 February 2026

Original Research

Behavioral Approaches to Pain

Preferences and Participation Factors of a Web-Based Mind–Body Intervention for Chronic Orofacial Pain: A Qualitative Study

Lovette BC, Levey N, Cliff KB, Bakhshaie J, Kulich R, Cheng HT, He S, Vranceanu AM, Greenberg J

Journal of Pain Research 2026, 19:585652

Published Date: 23 February 2026

Original Research

Acute Pain and Perioperative Care

Ultrasound-Guided Transversus Abdominis Plane Block Using 0.125% versus 0.25% Bupivacaine for Postoperative Opioid Consumption in Kidney Transplant Recipients: A Prospective, Randomized, Double-Blind Clinical Trial

Nonphiaraj S, Siwakul P, Sangsungnern P, Intrapongpan J, Theeragul S, Nuwatkrisin K, Somdee W, Wanphon K

Journal of Pain Research 2026, 19:578126

Published Date: 21 February 2026

Original Research

Behavioral Approaches to Pain

A Comprehensive Mendelian Randomization Study of Bidirectional Causal Relationships Between Pain and Mental Disorders

Liang X, Fan Y

Journal of Pain Research 2026, 19:561284

Published Date: 21 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Musculoskeletal Pain Among University Faculty: A Cross-Sectional Study of Prevalence, Determinants, and Associations with Work Performance and Occupational Stress

Elkholi SM, Alqabbani S, Hakami W, Althukair M, Aldhahi MI

Journal of Pain Research 2026, 19:575383

Published Date: 21 February 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Comparative Effectiveness of Non-Pharmacological Interventions for Pain and Quality of Life in Women with Endometriosis: A Systematic Review and Network Meta-Analysis

Zheng X, Wang Y, Li H, Zhang J, Liu J, Zheng X, Zhang J, Fan G, Sun Y, Li B, Jiao J, Zuo G, Fan X, She Y

Journal of Pain Research 2026, 19:577080

Published Date: 20 February 2026

Original Research

Pediatric Pain

Dissemination of Pediatric Chronic Pain Research: Views from Patients, Caregivers, and Healthcare Professionals

Hochreuter J, Nissen EK, Prchal A, Locher C, Heuss SC, Grätzer CR, Koechlin H

Journal of Pain Research 2026, 19:560855

Published Date: 20 February 2026

Original Research

Acute Pain and Perioperative Care

Effect of Stellate Ganglion Block on Postoperative Pain in Patients with Obstructive Sleep Apnea Syndrome: A Randomized Controlled Trial

Zhao L, Shen X, Li Y, Xu X, Zhan L

Journal of Pain Research 2026, 19:573822

Published Date: 20 February 2026

Original Research

Acute Pain and Perioperative Care

Impact of Analgesic Modalities on Postoperative Breakthrough Pain Following Anterior Cruciate Ligament Reconstruction: A Retrospective Study

Geng C, Mei Y, Deng Y, Dang R, Feng D, Zhang S, Cao H, Li Z, Zeng H

Journal of Pain Research 2026, 19:577026

Published Date: 19 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Ultrasound-Guided Hydrodissection Combined with Acupotomy Release versus Hydrodissection Alone for Deep Gluteal Syndrome: A Retrospective Study on Short-Term Efficacy

Tuo J, Wang J, Luo Y, Cao W

Journal of Pain Research 2026, 19:564639

Published Date: 19 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Safety, Tolerability, and Efficacy of Hox Alpha, a Dry Extract from Stinging Nettle Leaves versus OTC NSAIDs in Osteoarthritis: A Retrospective, Propensity-Matched 12-Week Analysis from the German Pain e-Registry (SIPHARO Study)

Überall MA, Küster MA, Müller-Schwefe PCG, Müller-Schwefe GH

Journal of Pain Research 2026, 19:546747

Published Date: 19 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

The Impact of Brain Morphometry on Low Back Pain Risk: A Mendelian Randomization Study

Liu Z, Li Y, Dai Y, Jiang B, Ma H, Tu Z, Wang B

Journal of Pain Research 2026, 19:565590

Published Date: 19 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Effectiveness of Jaw Exercises Applied in Addition to Cervical Stabilization Exercises in Individuals with Chronic Neck Pain: A Randomized Controlled Trial

Canli M, Özüdoğru A, Alkan H, Cigdem-Karacay B

Journal of Pain Research 2026, 19:584088

Published Date: 18 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Intravenous Pamidronate in Persistent Complex Regional Pain Syndrome (CRPS): A Retrospective Observational Study on Effectiveness and Tolerability

van der Spek DPC, Huygen FJPM, Hoeks SE, van Daele PLA, Dirckx M

Journal of Pain Research 2026, 19:573167

Published Date: 18 February 2026

Letter

Integrative/Acupuncture

Toward More Robust, Clinically Decision-Supportive Evidence: Methodological Reflections on a Meta-Analysis of Acupuncture for Fibromyalgia Syndrome [Letter]

Zhao FY, Fu QQ, Qian J

Journal of Pain Research 2026, 19:601404

Published Date: 18 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Association of Inflammatory Proteins with Neuropathic Pain: A Two-Sample Bidirectional Mendelian Randomization

Zhong J, Li H, Huang C, Zhang P, Pang X, Luo Z, Li C

Journal of Pain Research 2026, 19:570828

Published Date: 17 February 2026

Original Research

Pre-Clinical/Scientific

Reliability and Validity of Non-Invasive Electrical Detection and Pain Thresholds Using PainVision® in Healthy Young Adults

Yu S, Yang Z, Chen B, Wang L, Huang J, Gou L, Yang L

Journal of Pain Research 2026, 19:561240

Published Date: 17 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Patterns of Comorbidity Between Chronic Pain and Chronic Diseases in US Adults: A Cross-Sectional Analysis of NHANES Data

Yang W, Cai S, Chen X, Dong Y, Yang F, Yang H, Wang R, Song C, Zhou G

Journal of Pain Research 2026, 19:555970

Published Date: 17 February 2026

Original Research

Pre-Clinical/Scientific

Metabolomics Analysis Reveals Gut Microbiota-Associated Sakuranin Modulates Endometrial Stem Cell Differentiation and Inflammation to Alleviate Pain in Endometriosis

Shi W, Wang M, Jin Z, Chen X, Li J, Lai H, Li X, Zhong Q, Chen Y, Chen S

Journal of Pain Research 2026, 19:557430

Published Date: 17 February 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Pulsed Radiofrequency and Epigenetic Modulation of Pain Pathways: A Systematic Review Based on Preclinical Evidence

Occhigrossi F, Mosca J, Micheli F, Gazzeri R, Robinson CL, Lo Bianco G

Journal of Pain Research 2026, 19:582117

Published Date: 17 February 2026

Original Research

Integrative/Acupuncture

Clinical Efficacy of Acupuncture for Knee Osteoarthritis and Associated Changes in Serum Lipidomics: A Prospective Observational Cohort Study

Wang X, Li X, Zhang H, Xue N, Xu M, Li X, Yuan M, Chen D, Ni G, Lian X

Journal of Pain Research 2026, 19:578343

Published Date: 16 February 2026

Study Protocol

Acute Pain and Perioperative Care

Efficacy of Tender Point Infiltrations (TPI) in Patients with Acute and Subacute Zoster-Associated Pain: Study Protocol for a Randomized, Prospective, Multicenter, Blinded Endpoint, Open-Label Controlled Trial

Han R, Zhou X, Zhao Z, Luo F

Journal of Pain Research 2026, 19:575423

Published Date: 16 February 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Effectiveness of Radiofrequency Ablation for Chronic Low Back Pain: A Systematic Review of Sham-Controlled Randomized Controlled Trials

Shokanov T, Anashev T, Baktybergen K, Shaukhin Y

Journal of Pain Research 2026, 19:571566

Published Date: 16 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Lumbar Sympathicolysis Attenuates Refractory Chemotherapy-Induced Peripheral Neuropathy in the Lower Extremities: A Prospective, Real-World Study

Suo J, Zhang F, Fan B, Joshi KS, Ma D, Xie G

Journal of Pain Research 2026, 19:563861

Published Date: 16 February 2026

Original Research

Acute Pain and Perioperative Care

Effects of Lung-Protective Ventilation on Cerebral Oxygenation During One-Lung Ventilation in Neonates

Lv L, Zhang WZ, Zhang HP, Wei YW, Duan JW, Ren JM

Journal of Pain Research 2026, 19:559083

Published Date: 16 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Exploring Causal Associations Between Plasma Metabolites and Sciatica: A Two-Sample Mendelian Randomization Analysis

Yu S, Wei Q, Luo Y, Wu G

Journal of Pain Research 2026, 19:568746

Published Date: 13 February 2026

Study Protocol

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Intraspinal versus Extraspinal Acupotomy Decompression, or Their Combination, for Lumbar Disc Herniation: Protocol for a Three-Arm, Randomized, Single-Blind Controlled Trial

Yang W, Liu H, Liu M, Liu L, Liu F, Dong Z, Li X

Journal of Pain Research 2026, 19:584489

Published Date: 13 February 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Interventional Effects of Small Needle-Knife Combined with Exercise Therapy in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Xu Y, Yang Q, Xu J, Xiao N, Yang X, Yan H, Zhang J, Lu H, Liu X, Sheng L, Zhu R, Huang J, Xie J, Xie Z, Li Z

Journal of Pain Research 2026, 19:569310

Published Date: 13 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Central Sensitization Severity in Chronic Low Back Pain: Associations with Sleep, Distress, Cortisol, and Visuospatial Working Memory

Sahebalam M, Hatef B, Pirzad Jahromi G

Journal of Pain Research 2026, 19:583843

Published Date: 13 February 2026

Clinical Trial Report

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Deep or Superficial? Autologous Conditioned Serum for Cervical Pain with Degenerative Disc Disease – a Randomized Controlled Trial

Godek P, Paprocka-Borowicz M, Ptaszkowski K

Journal of Pain Research 2026, 19:579265

Published Date: 13 February 2026

Retraction

Pre-Clinical/Scientific

Neuropathic Pain Creates Systemic Ultrastructural Changes in the Nervous System Corrected by Electroacupuncture but Not by Pregabalin [Retraction]

Gao L, Zhang JF, Williams JP, Yan YN, Xiao XL, Shi WR, Qian XY, An JX

Journal of Pain Research 2026, 19:602597

Published Date: 12 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Impact of Postoperative Chronic Back Pain Syndrome on the Incidence of Psychiatric and Brain Disorders, and All-Cause Mortality

Park D, Lee WR, Bang M, Park SJ, Kim JH, Kim HS

Journal of Pain Research 2026, 19:582506

Published Date: 11 February 2026

Review

Behavioral Approaches to Pain

A Scoping Review of Flotation-REST (Restricted Environmental Stimulation Therapy) for Chronic Pain and Associated Comorbidities

Stuart SJ, Achury LK, Kline M, Bair MJ

Journal of Pain Research 2026, 19:565238

Published Date: 11 February 2026

Original Research

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

A Study on the Efficacy and Safety of Intravenous Lidocaine Infusion Combined with Pulsed Radiofrequency in Preventing Postherpetic Neuralgia: A Randomized, Double-Blind, Controlled Trial

Xu P, Fan H, Yu M, Fei Y

Journal of Pain Research 2026, 19:562972

Published Date: 11 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Metabolomic Insights into Reprogrammed Caffeine Metabolism in the Hippocampus of Myofascial Pain Syndrome Rats

Sheng D, Meng Y, An S, Wu Z, Yao J, Huang Y, Wang L

Journal of Pain Research 2026, 19:557588

Published Date: 11 February 2026

Response to Letter

Headache and Facial Pain

Episodic Migraine Pain Curves: Real-Time Smartphone-Based Analysis and Clinical Implications [Response to Letter]

Gago-Veiga AB, Gonzalez-Martinez A, Quintas S, Vieira A, Gálvez-Goicuría J, Sanz-García A, Ayala JL, Sobrado M, Vivancos J, Pagan J

Journal of Pain Research 2026, 19:598383

Published Date: 11 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Efficacy and Spinal Noradrenergic Mechanisms of Contralateral Melittin Acupuncture Against Paclitaxel-Induced Peripheral Neuropathic Pain in Rats

Li D, Xue F, Wu Y, Chang L, Song Y, Du X, Wu J, Liu Q, Wang T

Journal of Pain Research 2026, 19:584909

Published Date: 11 February 2026

Original Research

Integrative/Acupuncture

Analgesic Efficacy of a Novel Traditional Chinese Medicine Ointment Against Mechanical Allodynia in Rat Models

Liu H, Deng J, Wei J, Wu J, Gan Y, Hu Y, Mo H

Journal of Pain Research 2026, 19:575860

Published Date: 10 February 2026

Original Research

Acute Pain and Perioperative Care

Analysis of the Current Status of Acute Postoperative Pain and Influencing Factors of Moderate to Severe Pain in Adult Patients Undergoing Ophthalmic Surgery Under General Anesthesia

Zhang X, Ren J, Li YN, Zeng JH, Tang J, Tang L

Journal of Pain Research 2026, 19:574297

Published Date: 8 February 2026

Review

Cancer Pain and Palliative Care

Oral Ketamine for Chronic Pain: Towards an Evidence-Based Dosing Regimen

Winegarden J, Brose A, Storm A, Mortensen A, Carr DB

Journal of Pain Research 2026, 19:545221

Published Date: 7 February 2026

Letter

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Cross-Cultural Adaptation and Validation for Central Aspects of Pain in the Knee Questionnaire Based on Chinese Patients Undergoing Total Knee Arthroplasty for Knee Osteoarthritis [Letter]

Goyal K, Goyal M, Singh C

Journal of Pain Research 2026, 19:596217

Published Date: 7 February 2026

Study Protocol

Integrative/Acupuncture

The Effectiveness of Huangkui Lianchang Decoction Enema Solution Compared with Mesalazine Enema for Mild-to-Moderate Active Distal Ulcerative Colitis: Study Protocol of a Multicenter, Prospective, Randomized Controlled Trial

Zhu Y, Wang R, Ding H, Li H, Zhao Y, Chen K, Zeng T, Ma Y, Chen C, Bu Z, Zhang J, Yang Y, Chen Y

Journal of Pain Research 2026, 19:574028

Published Date: 5 February 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Abnormal Regional Brain Functional Activity and Brain Network Connectivity in Primary Trigeminal Neuralgia Patients: An Activation Likelihood Estimation Meta-Analysis Based on Resting-State fMRI

Yang H, Zhang C, Sun B, Li M, Xu X, Yang H

Journal of Pain Research 2026, 19:573011

Published Date: 4 February 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Dual-Site Pain in the Low Back and Knee as a Risk Factor for Dementia: A Population-Based Cohort Study

Endo Y, Kobayashi H, Watanabe K, Otani K, Sekiguchi M, Ono R, Konno SI, Matsumoto Y

Journal of Pain Research 2026, 19:570261

Published Date: 3 February 2026

Review

Integrative/Acupuncture

Efficacy of Acupuncture in Patients with Fibromyalgia Syndrome: A Meta-Analysis

Jin L, Zhou Y, Li L, Song F, Zhou Y

Journal of Pain Research 2026, 19:568235

Published Date: 3 February 2026

Original Research

Pain in Older Adults

Clinical Validation of Quality Indicators for the Pharmacological Management of Chronic Non-Cancer Pain in Older Adult Inpatients

Abderhalden J, Meyer-Massetti C, Müller D, Cadisch P, Bertschi D, Goetschi AN

Journal of Pain Research 2026, 19:560808

Published Date: 2 February 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Molecular Mechanisms and Therapeutic Targets for Pain Following Osteoporotic Vertebral Fractures

Zhou H, Wu K

Journal of Pain Research 2026, 19:567567

Published Date: 2 February 2026

Original Research

Integrative/Acupuncture

Impact of Electroacupuncture on the Expression Profile of the Anterior Cingulate Cortex in a Rat Model of Irritable Bowel Syndrome Based on Transcriptome Sequencing and Bioinformatics Analysis

Guo Y, Wang D, Chen M, Wei X, Yang Z, Wang Z, Zhang H

Journal of Pain Research 2026, 19:574208

Published Date: 2 February 2026

Review

Cancer Pain and Palliative Care

Reshaping Precision Cancer Pain Management with Multimodal Artificial Intelligence: A Review on Subtyping and Treatment Response Prediction

Wang X, Tang X, Wei C, Xu J, Sun K, Zhou G

Journal of Pain Research 2026, 19:570481

Published Date: 2 February 2026

Review

Pharmacology

Review of Physiology, Pathology, and Pharmacology of Voltage-Gated Sodium Channels in Regards to the Potential Role of NaV 1.8 Selective Inhibitor, Suzetrigine, for Chronic Pain Management

Lam CM, Robinson CL, Aiyer R, Mata R, Xie K, Slitzky M, Latif H, Braun EB, Schatman ME, Gilligan C, Soin A, Latif U

Journal of Pain Research 2026, 19:577002

Published Date: 2 February 2026

Clinical Trial Report

Pharmacology

Reconsolidation Blockade with Propranolol as a Novel Treatment for Chronic Low-Back Pain: A Double-Blind Randomized Placebo-Controlled Feasibility Study

Coulombe-Leveque A, Lafrenaye S, Brunet A, Marchand S, Léonard G

Journal of Pain Research 2026, 19:566843

Published Date: 31 January 2026

Review

Pain Education and Early Career Investigators

Transitional Pain Services and Clinics: A Scoping Review of Recent Literature

Freitag HE, Melvin RL, Godwin RC, Ness TJ

Journal of Pain Research 2026, 19:548214

Published Date: 31 January 2026

Study Protocol

Acute Pain and Perioperative Care

Effects of Preoperative Stellate Ganglion Block on Postoperative Sore Throat and Hoarseness in Patients Undergoing Double-Lumen Endobronchial Intubation: Protocol for a Prospective Randomized Controlled Trial

Chen Z, Tan Y, Cong P, Jin Y, Jin Y, Li N

Journal of Pain Research 2026, 19:573249

Published Date: 30 January 2026

Original Research

Integrative/Acupuncture

Periplaneta americana Powder Alleviates Neuropathic Pain and is Associated with Gut Microbiota Changes in Rats

Luo D, Jia S, He W, Fan Z, Yin W

Journal of Pain Research 2026, 19:564911

Published Date: 29 January 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Prevalence and Nomogram-Based Prediction Model of Neuropathic Pain After Knee Arthroplasty

Xin Y, Wang C, Li J, Fang X, Huang Z, Bai G, Li W, Zhang W, Zhang C

Journal of Pain Research 2026, 19:565227

Published Date: 29 January 2026

Original Research

Acute Pain and Perioperative Care

Comparison of the Postoperative Analgesic Effects of TAP and M-TAPA Blocks in Laparoscopic Appendectomy: A Pilot Randomized Controlled Trial

Tekcan MN, Balcı F, Gündoğdu O, Avcı O

Journal of Pain Research 2026, 19:575244

Published Date: 28 January 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

In vitro Effects of Gadoteric Acid and Iobitridol Toxicity and Platelet-Rich Plasma-Mediated Protection in Human Annulus Fibrosus and Nucleus Pulposus Cells

Mercader-Ruiz J, Marijuán-Pinel D, Sánchez A, Morales CA, Beitia M, Fiz N, Delgado D, Sánchez M

Journal of Pain Research 2026, 19:550889

Published Date: 27 January 2026

Original Research

Opioids and Substance Abuse

Adverse Drug Events Associated with Opioid Treatment for Pain After Motor Vehicle Crash

Zullo AR, Balog S, Khan MA, Pfeiffer MR, Riester MR, Curry AE, Beaudoin FL, Oganisian A, Marshall BD, Dow PM, Dana BA, Joyce NR

Journal of Pain Research 2026, 19:529856

Published Date: 27 January 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Causal Brain Network Alterations Across Disease Stages in Herpes Zoster and Postherpetic Neuralgia

Zou W, Li Z, Gu L, Jiang X, Xiong J, Qin S, Lu J, Jiang J

Journal of Pain Research 2026, 19:560620

Published Date: 24 January 2026

Original Research

Acute Pain and Perioperative Care

Sensory Block Height and Risk of Maternal Fever in Epidural Labour Analgesia: A Prospective Cohort Study

Tian L, Wei X, Cao R, Tang Y, Liang L, Jia F, Yang L, Li N, Xu J, Wang Y, Liu B, Li X, Xie M

Journal of Pain Research 2026, 19:565186

Published Date: 24 January 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Intradiscal Procedures for Discogenic Low Back Pain: Considerations and Implications – A Narrative Review

Chang MC, Yang S

Journal of Pain Research 2026, 19:579829

Published Date: 24 January 2026

Corrigendum

Opioids and Substance Abuse

Pain Intensity in Patients with Opioid Use Disorder on Extended-Release Naltrexone or Opioid Agonists; The Role of COMT rs4680 and OPRM1 rs1799971: An Exploratory Study [Corrigendum]

Juya F, Sannes AC, Solli KK, Weimand B, Gjerstad J, Tanum L, Mordal J

Journal of Pain Research 2026, 19:598098

Published Date: 24 January 2026

Clinical Trial Report

Acute Pain and Perioperative Care

The Effect of Cocktail Formula Solution for Erector Spinae Plane Block on Postoperative Pain After Laparoscopic Major Upper Abdominal Surgery: A Single-Center Randomized Controlled Study

Lu D, Chen H, Hu J, He X, Bao L, Xu B, Zhang S, Fan J, Wang R

Journal of Pain Research 2026, 19:566625

Published Date: 24 January 2026

Letter

Headache and Facial Pain

Episodic Migraine Pain Curves: Real-Time Smartphone-Based Analysis and Clinical Implications [Letter]

Zhang Y, Wang J, Zhao P, Chen X, Zhang S, Zhang X

Journal of Pain Research 2026, 19:594636

Published Date: 24 January 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Ultrasound-Guided Atelocollagen Injection for Chronic Pain After Spinal Surgery: A Retrospective Cohort Study

Kim H, Nam S, Lee K, Yu S, Moon JY, Kim J

Journal of Pain Research 2026, 19:549827

Published Date: 23 January 2026

Clinical Trial Report

Acute Pain and Perioperative Care

Incidence of Hemidiaphragmatic Paresis After Low Volume of Anterior Suprascapular Nerve Block for Arthroscopic Shoulder Surgery: A Randomized, Double-Blind Controlled Trial

Tunprasit C, Areeruk P, Chawachart C, Nitithamakul W, Saeaeh L, Termpornlert S, Arnuntasupakul V

Journal of Pain Research 2026, 19:568402

Published Date: 23 January 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Neuropathic Pain and Quality of Life: A Cross-Sectional Study in Brachial Plexus Injury

Cardoso MDM, Gushikem A, Felipe R, Araújo PVS, Gepp R

Journal of Pain Research 2026, 19:571035

Published Date: 22 January 2026

Review

Integrative/Acupuncture

Auricular Acupoint Selection Patterns for Knee Osteoarthritis Pain Relief: A Systematic Review and Data Mining Analysis

Li Y, Zhang X, Liu M, Wang Y, Shen Z, Shan Y

Journal of Pain Research 2026, 19:568124

Published Date: 21 January 2026

Review

Integrative/Acupuncture

Stage-Specific Mechanisms of Manual Acupuncture and Electroacupuncture in Inflammatory Pain: A Time-Dependent Review

Liu B, Wang J, Lim HY, Liu J, Hou Z, Huang J, Xie G, Feng X, Xie J, Xiong X, Yu S

Journal of Pain Research 2026, 19:577362

Published Date: 21 January 2026

Clinical Trial Report

Acute Pain and Perioperative Care

Perioperative Music Therapy Enhances Pain Management and Sleep Quality in Patients Aged 50–70 Years Undergoing Total Knee Arthroplasty: A Randomized Controlled Trial

Yang L, Liu X, Fu X, Qing Z, Li Y, Yang G

Journal of Pain Research 2026, 19:560546

Published Date: 21 January 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

A Novel Mobile C-Arm Fluoroscopic Imaging of the Foramen Ovale and Its Anatomical Principles

Qiu T, Guo Q, Kong T, Yin M, Bai Q, Zhang M, Wang G, Tao S, Liu Z

Journal of Pain Research 2026, 19:557040

Published Date: 21 January 2026

Original Research

Behavioral Approaches to Pain

A Pain Memory “Trace”: Cumulative Pain Perception and Damping During Fight-or-Flight Response Modeled with a Lotka-Volterra-Style Coupled Feedback Control Loop System

Fink W, Raffa RB

Journal of Pain Research 2026, 19:561278

Published Date: 21 January 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Multifidus Muscle Atrophy Predicts Spinal Cage Subsidence After Lumbar Fusion

Zhang C, Li C, Wu X, Sun X

Journal of Pain Research 2026, 19:534086

Published Date: 20 January 2026

Review

Cancer Pain and Palliative Care

Efficacy of Acupuncture Combined with the Three-Step Analgesic Protocol in Treating Pain in Liver Cancer Pain: A Bayesian Network Meta-Analysis

Li T, Hu J, Chen J, Zeng L

Journal of Pain Research 2026, 19:562271

Published Date: 20 January 2026

Review

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

The American Society of Pain and Neuroscience (ASPN) Evidence-Based Consensus Recommendations on Programming and Coding Implantable Spinal Cord Stimulation Devices for Treatment of Chronic Intractable Pain

Deer TR, Nairizi A, Hunter CW, Kalia H, Pope JE, Cornidez EG, Sayed D, Smith GL, Goree JH, Antony AB, Staats PS, Gilligan C, Karcz M, Trainor D, Broachwala MY, Reynolds D, Bloomfield A, Vu CM, Lad SP, Trainer R, Monacelli C, Devers J, Petersen EA

Journal of Pain Research 2026, 19:541843

Published Date: 18 January 2026

Editorial

Pain Education and Early Career Investigators

Volume without Value: The Empty Metrics of Pain Medicine Social Media Influence

Pritzlaff SG, Singh N, Schatman ME, Flower V, Sheth SJ

Journal of Pain Research 2026, 19:595271

Published Date: 17 January 2026

Original Research

Minimally Invasive Spine Procedures, Neuromodulation and Interventional Pain

Smart Processing and Intelligent Navigation for Evaluation (SPINE): Comparing Clinicians and AI Language Model (GPT-4) in Spinal Cord Stimulation Candidate Selection

Lo Bianco G, Therond A, D’angelo FP, Kapural L, Diwan S, Staats P, Li S, Christo PJ, Deer TR, Robinson CL

Journal of Pain Research 2026, 19:559514

Published Date: 17 January 2026

Review

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Comparative Effectiveness of Chinese Patent Medicines for Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Bayesian Network Meta-Analysis

Lin S, Huang W, Liu R, Xu J, Li Y

Journal of Pain Research 2026, 19:560430

Published Date: 14 January 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Metabolic Syndrome and Low Back Pain: Evidence from Cross-Sectional and Mendelian Randomization Analysis

Wang X, Sun D, Duan H, Yang Y, Zhao H

Journal of Pain Research 2026, 19:567811

Published Date: 14 January 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Mid-to-Long Term Radiological and Clinical Outcomes of Oblique Lateral Interbody Fusion versus Posterior Lumbar Interbody Fusion for Severe Lumbar Spinal Stenosis: A Retrospective Comparative Study

Hu J, Xu H, Ma X, Yang X, Zhang S

Journal of Pain Research 2026, 19:552131

Published Date: 13 January 2026

Original Research

Surgical Approaches to Pain

Comparison of Quadratus Lumborum Plus Modified Erector Spinae Plane Block versus Pericapsular Nerve Group Block Plus Lateral Femoral Cutaneous Block on Postoperative Analgesia and Functional Recovery in Total Hip Arthroplasty: A Retrospective Propensity Score-Matched Study

Wu X, Wang M, Du M, Wang Y, Chen X, Zhang D, Xu Y

Journal of Pain Research 2026, 19:567827

Published Date: 13 January 2026

Hypothesis

Pre-Clinical/Scientific

An Overview of Ischemic Preconditioning as a Potential Therapeutic Target for Chronic Muscle Pain

Zhang Q, Luo J

Journal of Pain Research 2026, 19:546782

Published Date: 13 January 2026

Original Research

Behavioral Approaches to Pain

Pain Catastrophizing After Early-Stage Lung Cancer Surgery: The Mediating Effects of Interoceptive Awareness, Negative Attentional Bias, and Social Support

Bian G, Sun X, Chang Q, Liu L, Zhang C

Journal of Pain Research 2026, 19:569494

Published Date: 13 January 2026

Original Research

Opioids and Substance Abuse

Comparative Safety Analysis of Hydromorphone and Morphone Sulfate: Evidence from the 2004–2024 FAERS

Chen X, Yang C, Lin Z

Journal of Pain Research 2026, 19:559014

Published Date: 13 January 2026

Original Research

Headache and Facial Pain

Psychosocial, Behavioral, and Quality of Life Insights in TMDs: A Comparative Exploration of Young and Mature Patients

Yap AU, Zheng Y, Yang M, Liu T, Li Y, Hu T, Wang J, Xiong X

Journal of Pain Research 2026, 19:540623

Published Date: 13 January 2026

Review

Nursing in Pain Care

Prevention and Management of Wound Procedural Pain Management in Adult Patients with Open Wounds: Integration of the Latest Clinical Evidence

Yao H, Yang F, Ye X, Yang Y, Li J

Journal of Pain Research 2026, 19:563157

Published Date: 12 January 2026

Clinical Trial Report

Surgical Approaches to Pain

Postoperative Pain After Transapical Beating-Heart Septal Myectomy for Hypertrophic Obstructive Cardiomyopathy: A Retrospective Study

Qiu J, Li Y, Li R, Fang J, Liu W, Mei W, Wei X, Yao W

Journal of Pain Research 2026, 19:562160

Published Date: 12 January 2026

Original Research

Musculoskeletal Pain/Rehabilitation and Neuropathic Pain

Self-Management, Fear of Movement, and Pain in Working Adults with Low Back Pain: A Qualitative Longitudinal Study

Roine M, Karvonen E, Munukka M, Heinonen A, Vuoskoski P

Journal of Pain Research 2026, 19:549844

Published Date: 10 January 2026

Original Research

Integrative/Acupuncture

Pricing, Popularity, and Customer Satisfaction in Online Pain-Relief Products: An AI-Powered Analysis

Jumreornvong O, Kantagowit P, Parnicharoende R, Yong RJ, Lo Bianco G, Ruan QZ, Hasoon J, Chung M, Schatman ME, Rullo G, Christo PJ, Issa M, Robinson CL

Journal of Pain Research 2026, 19:550032

Published Date: 9 January 2026

Original Research

Headache and Facial Pain