Diabetes, Metabolic Syndrome and Obesity
Diabetes Pathophysiology and Complications
Section Editor(s):
Dr Rebecca Conway, Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA
The pathophysiology and complications of diabetes section welcomes experimental, clinical, and translational research related to the onset and progression of diabetes or its complications. This may be laboratory, animal or human original research studies, meta-analyses, mini-reviews, or reviews. The complications include, but are not limited to, diabetic retinopathy, nephropathy, neuropathy cardiovascular disease, and peripheral vascular disease.
Latest articles in Diabetes Pathophysiology and Complications:
- 25 records -
SLC30A8 Promoter Hypomethylation is Associated with Impaired Renal Function in Type 2 Diabetes: A Cross-Sectional Study
Guo C, Yang W, Xue R, Zhou Q, Liang Y, Zhang XL
Diabetes, Metabolic Syndrome and Obesity 2026, 19:600905
Published Date: 12 May 2026
Development and Validation of a Nursing-Integrated Nomogram to Predict 1-Year Ulcer Recurrence in Patients with Diabetic Foot Ulcers After Endovascular Therapy
Fu L, Zeng W, Ding H, Chen Z, Chen X
Diabetes, Metabolic Syndrome and Obesity 2026, 19:591186
Published Date: 23 April 2026
The Central Role of Lipid Metabolism Disorders in Diabetes Mellitus: Mechanisms, Clinical Manifestations, and Emerging Therapeutic Strategies
Yang Q, Liu X, Zhang T, Zhao X, Xiao X
Diabetes, Metabolic Syndrome and Obesity 2026, 19:591764
Published Date: 16 April 2026
Skin Organoids in Diabetic Chronic Wounds: Current Status and Future Perspectives
Wang Z, Hou M, Pei J, Gao F, Li Z
Diabetes, Metabolic Syndrome and Obesity 2026, 19:598026
Published Date: 16 April 2026
Early Pregnancy Triglyceride to HDL-C Ratio Predicts Gestational Diabetes Mellitus and Neonatal Hypoglycemia: A Retrospective Cohort Study
Jiang L, Shao H, Wang X, Wu J, Dong F
Diabetes, Metabolic Syndrome and Obesity 2026, 19:590161
Published Date: 11 April 2026
Clinical Significance of Serum CCR2 and IDO1 in Diabetic Peripheral Neuropathy
Liu Y, Yang Q
Diabetes, Metabolic Syndrome and Obesity 2026, 19:579354
Published Date: 25 March 2026
Construction of a Risk Prediction Model and Associative Path Analysis for Impaired Awareness of Hypoglycemia in People with Diabetes
Wen X, Chen L, Mo Y, Guo H, Pei R, Lyu Y, Luo H, Wang J
Diabetes, Metabolic Syndrome and Obesity 2026, 19:579326
Published Date: 25 March 2026
Clinical Characteristics and Development of a Risk-Identification Model for Incidentally Detected Cancer in Patients with Diabetes: A Case–Control Study
Cheang N, Chen X, Zhang H, Su Q, Du S
Diabetes, Metabolic Syndrome and Obesity 2026, 19:581946
Published Date: 24 March 2026
Metabolic Crosstalk in Diabetic Kidney Disease: Synergistic Effects of Glucotoxicity and Lipotoxicity
Cao J, Dun Z, Tian D, Qiao Z, Wang Y
Diabetes, Metabolic Syndrome and Obesity 2026, 19:580866
Published Date: 23 March 2026
Thyroid Hormone Indices and Histopathological Severity of Diabetic Nephropathy in Euthyroid Patients with Type 2 Diabetes: A Biopsy-Based Cross-Sectional Study
Wang X, Zhang C, Zhao X, Zhao S, Zhang F, Li C, Hao Y
Diabetes, Metabolic Syndrome and Obesity 2026, 19:589576
Published Date: 23 March 2026
Quality of Clinical Practice Guidelines for Diabetic Foot Management: A Systematic Review Using the AGREE II and AGREE-REX Instruments
Song Y, Cui ZF, Wu ZQ, Liu XB, Li WQ, Zhu C, Que T, Zhao SS, Wang XL, Yang GX, Liu WJ
Diabetes, Metabolic Syndrome and Obesity 2026, 19:586150
Published Date: 23 March 2026
A Novel Nomogram for Diabetic Retinopathy Prediction in Young and Middle-Aged Patients with Type 2 Diabetes
Ma L, Shi S, Wang J, Shi S, Zhang Y, Wang X, Shi S, Huang K, Zhang Y
Diabetes, Metabolic Syndrome and Obesity 2026, 19:582107
Published Date: 12 March 2026
Association of NLRP3 Inflammasome rs10754558 Polymorphism with Type 2 Diabetes Mellitus and Its Complications: Clinical and Bioinformatics Study
Ahmed AM, Al-Nakhle HH, Aman AM, Yousuf AM, Muddathir ARM, Almutawif YA, Eweda SM, Alsubhi AS, Aljohani HM, Alhamawi RM, Almalki F, Eltahir Z
Diabetes, Metabolic Syndrome and Obesity 2026, 19:586787
Published Date: 10 March 2026
Clinical Characteristics and Risk Factors of Exogenous Insulin Antibody Syndrome in Patients with Diabetes: A Retrospective Cross-Sectional Study
Zhou J, Li J, Wang Z, Dai X, Zhang N, Kong L, Wu S, Liu J, Zhang Y, Han T
Diabetes, Metabolic Syndrome and Obesity 2026, 19:571981
Published Date: 7 March 2026
Development and External Validation of a Machine Learning Model for Predicting Wound Infection in Diabetic Foot Ulcers
Nie X, Jiang Y, Meng X, Liu J, Zhao H, Chen Y, Wang J, Lu T
Diabetes, Metabolic Syndrome and Obesity 2026, 19:586810
Published Date: 7 March 2026
Tissue Iron Predicts Metformin Responsiveness in a Mouse Model and in Humans with Type 2 Diabetes
Harrison AV, Usoh CO, Sink S, Jain S, Berry-Price HM, Lorenzo FR, McClain DA
Diabetes, Metabolic Syndrome and Obesity 2026, 19:580024
Published Date: 5 March 2026
Efficacy and Safety of Chinese Medicine Eye Nebulization in the Treatment of Diabetic Retinopathy: Protocol for a Double-Blind, Randomized, Placebo-Controlled Trial
Peng S, Ren X, Nie Q, Gao Y, Yu H, Wang J, Li J, Xu C, Lee M
Diabetes, Metabolic Syndrome and Obesity 2026, 19:576100
Published Date: 3 March 2026
Association Between Serum Vitamin D3 Levels and Diabetic Macular Edema in Patients with Type 2 Diabetes: A Retrospective Case-Control Study
Al-latayfeh M, Shatnawi RA, Abu-Ain MS, Alotaibi TM, Albazee E, Al-balawi M, Alnifise MH
Diabetes, Metabolic Syndrome and Obesity 2026, 19:588850
Published Date: 20 February 2026
Causal Risk Factors for Type 1 Diabetes in Mendelian Randomization Studies: A Systematic Review and Meta-Analysis
Li M, Shen P, Liu C, Li J, Qiu S, Wang Z
Diabetes, Metabolic Syndrome and Obesity 2026, 19:568784
Published Date: 19 February 2026
Competing Risks Analysis for Neutrophil to Lymphocyte Ratio as a Predictor of Diabetic Nephropathy Incidence
Song X, Dong W, Fu Y, Wang J, Wang J
Diabetes, Metabolic Syndrome and Obesity 2026, 19:570594
Published Date: 18 February 2026
Serum Uric Acid-to-Creatinine Ratio Is Independently Associated with Sudomotor Dysfunction in Type 2 Diabetes: A Cross-Sectional Study
Peng J, Liang S, Tang X, Chen X, Xu H, Liu J, Xu W, Shui X, Yang X
Diabetes, Metabolic Syndrome and Obesity 2026, 19:562091
Published Date: 18 February 2026
Endothelial Metabolic Reprogramming Links Diabetes to Atherosclerosis
Pan Y, Si J
Diabetes, Metabolic Syndrome and Obesity 2026, 19:565805
Published Date: 11 February 2026
Multi-Radiomics Features of Super-Resolution MRI for Predicting Minor Amputation in Wagner 3 Diabetic Foot Ulcers
Cao B, Zhong J, Zhang J, Zhao D
Diabetes, Metabolic Syndrome and Obesity 2026, 19:565938
Published Date: 10 February 2026
Promising Biomarkers for Early Diagnosis: Advances in Understanding the Pathogenesis of Diabetic Peripheral Neuropathy
Lyu Q, Tan Y, Zeng X, Peng S, Lee M
Diabetes, Metabolic Syndrome and Obesity 2026, 19:568751
Published Date: 10 February 2026
The TRIM14-KIF1B Axis Drives Renal Injury in Diabetic Nephropathy Through TLR4/NF-κB Pathway Modulation
Chen J, Han X, Cao Y, Song J, Wang C, Pan T
Diabetes, Metabolic Syndrome and Obesity 2026, 19:562762
Published Date: 10 February 2026