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Neuropsychiatric Disease and Treatment

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ISSN: 1178-2021

Archive: Volume 22, 2026


Original Research

Cistanche deserticola Stem Extract Attenuates Depression Through NF-κB Pathway Modulation: Insights from Network Pharmacology and Experimental Validation

Jiang S, An Z, Hu Q, Song Y, Zhao X, Gao S, Jia Q, Xu B

Neuropsychiatric Disease and Treatment 2026, 22:586181

Published Date: 13 May 2026

Original Research

Functional Impairment and Post-Stroke Depression: Potential Roles of Sleep Quality and Fatigue in a Cross-Sectional Structural Equation Analysis

Hu QY, Yang KY, Ming YF, Sun SJ, Liu J

Neuropsychiatric Disease and Treatment 2026, 22:606661

Published Date: 12 May 2026

Study Protocol

Psychomotor Rehabilitation for Pediatric Delirium: A Study Protocol for a Randomized Controlled Trial Investigating Efficacy and Brain Electrophysiological Mechanisms

Zhang X, Ren YQ, Shan YJ, Zhou YP, Dou JY, Lu Y, Cui Y, Ao LJ

Neuropsychiatric Disease and Treatment 2026, 22:595008

Published Date: 11 May 2026

Review

Role of Electroencephalographic Biomarkers as Predictors of Post-Stroke Cognitive Outcomes in Patients with Cerebral Infarction: Literature Review

Pu D, Xiong Y

Neuropsychiatric Disease and Treatment 2026, 22:566481

Published Date: 11 May 2026

Original Research

Clinical Benefit and Risk Profile of TV-46000 for Patients with Schizophrenia as Assessed by Number Needed to Treat and Number Needed to Harm

Citrome L, Franzenburg KR, Suett M, Tohami O, Sharon N, Jehassi A, Harary E, Yu D, Correll CU

Neuropsychiatric Disease and Treatment 2026, 22:534730

Published Date: 8 May 2026

Review

Central Neurobiological Mechanisms of Acupuncture in Post-Stroke Depression: Multi-Target and Network-Based Regulation

Cao J, Xu Y, Mao H, Chen J, Ding D, Xu X

Neuropsychiatric Disease and Treatment 2026, 22:596862

Published Date: 6 May 2026

Review

Efficacy and Safety of Escitalopram for Major Depressive Disorder in Children and Adolescents: A Systematic Review and Meta-Analysis with Age-Specific Findings

Maneeton B, Maneeton N, Pojanapotha P, Putthisri S, Oon-arom A, Karawekpanyawong N, Kawilapat S, Maneeton P, Srichan K

Neuropsychiatric Disease and Treatment 2026, 22:595606

Published Date: 5 May 2026

Original Research

Peripheral Blood Regulatory T Cells and IL-6 are Associated with Cognitive Impairment After Acute Ischemic Stroke

Chang Y, Zhang X, Yu C, Zhu L, Sun S, Sun Z

Neuropsychiatric Disease and Treatment 2026, 22:590109

Published Date: 1 May 2026

Perspectives

Optimizing Identification and Management of Depression in Neurological Diseases: A Narrative Review and Expert Perspective

Bartova L, Beuster ML, Bonetti B, Maina G, Morgado P, Nyberg J

Neuropsychiatric Disease and Treatment 2026, 22:575685

Published Date: 1 May 2026

Original Research

Sleep-Related Problems and Problematic Smartphone Use in Young Adult Males: Findings from a Short-Term Behavioral Restriction Study

Özen Gökmuharremoğlu Ö, Çoban Taşkın A

Neuropsychiatric Disease and Treatment 2026, 22:597802

Published Date: 30 April 2026

Review

Insulin Resistance Across Cerebrovascular and Related Disorders: Mechanisms, Measurement, Genetics, and Clinical Implications

Chen K, Nong Y, Liu Y, Ye Z

Neuropsychiatric Disease and Treatment 2026, 22:575306

Published Date: 30 April 2026

Original Research

Association Between Frontotemporal Atrophy and Cognitive Impairment in Patients with Schizophrenia Based on Computed Tomography Imaging

Wang Y, Yang J, Ye Y, Lu L, Wang H, Guo P, Hou N, Huang X, Li C

Neuropsychiatric Disease and Treatment 2026, 22:602462

Published Date: 30 April 2026

Original Research

Long-Term Effectiveness and Safety of LCIG in Romania. 3-year Results from a Prospective, Observational Study (DUOGLOBE)

Szasz JA, Constantin VA, Jianu DC, Dan TF, Dulamea AO, Sabau M, Vasile MT, Bergmann L, Popescu D, Simu MA

Neuropsychiatric Disease and Treatment 2026, 22:564900

Published Date: 28 April 2026

Study Protocol

Clinical Efficacy of Integrated Acupuncture and Moxibustion Therapy Combined with Drugs in the Treatment of Acute Depressive Disorder: Protocol for a Pragmatic Randomized Controlled Trial

Wu Q, Liu Y, Lin D, Wang S, Liang X, Wu B, Wan L, Liu Y, Wang T, Liu H, Lai L, Sun L, Fu W

Neuropsychiatric Disease and Treatment 2026, 22:601078

Published Date: 27 April 2026

Study Protocol

An Open-Label, Single-Arm Trial of Transcranial and Intranasal Photobiomodulation in Patients with Schizophrenia: A Study Protocol

Yamada R, Izumi S, Oba MS, Noda T, Stickley A, Sumiyoshi T

Neuropsychiatric Disease and Treatment 2026, 22:585770

Published Date: 21 April 2026

Study Protocol

Acupuncture and Tuina Combined with Educational Rehabilitation for Children with Autism Spectrum Disorder: Study Protocol for a Single-Center, Three-Arm, Pragmatic Randomized Controlled Trial

Wang X, Dong XQ, Tao YW, Du XG, Zhao NX, Song HJ

Neuropsychiatric Disease and Treatment 2026, 22:587139

Published Date: 21 April 2026

Original Research

Parallel Single-Tissue Summary-Data Mendelian Randomization and Functional Validation Identify the ARRDC1 Promoter SNP rs4494021 as a Genetic Marker Associated with Anxiety Disorders

Wang L, Xu Z, Luo G, Wei W, Guo M, Yuan Y, Shi B, Guan H, Liu S, Li X

Neuropsychiatric Disease and Treatment 2026, 22:593689

Published Date: 21 April 2026

Review

Mechanism-Driven Translation of Electroacupuncture for Depression: Bridging the Gap Between Preclinical and Clinical Research

Cao J, Ding D, Ming X, Liu C, Xu Y

Neuropsychiatric Disease and Treatment 2026, 22:598864

Published Date: 21 April 2026

Short Report

Brexpiprazole for Agitation in Patients with Alzheimer’s Dementia with and without Co-Occurring Psychosis: Post Hoc Analysis of Short- and Long-Term Trials

Tariot PN, Chumki SR, Wang D, Such P, Palma AM, Zhang Z, Montano CB

Neuropsychiatric Disease and Treatment 2026, 22:586701

Published Date: 21 April 2026

Original Research

Neurocognitive and Psychiatric Outcomes Following Mild to Moderate COVID-19: A Longitudinal Comparison of Alpha/Delta and Omicron Variants

Lynch ST, Dornbush R, Aftab S, Mansour R, Libretti A, Shahar S, Bilal A, Klepacz L, Ferrando SJ

Neuropsychiatric Disease and Treatment 2026, 22:594322

Published Date: 18 April 2026

Review

Traditional Chinese Medicine for Alzheimer’s Disease: Current Evidence and Chemometric Approaches for Multi-Target Evaluation

Sun X, Yang L, Wang X

Neuropsychiatric Disease and Treatment 2026, 22:590661

Published Date: 18 April 2026

Original Research

Wavelet Entropy Analysis of EEG Signals During Wake and Sleep in Patients with Alzheimer’s Disease: A Pilot Study

Tong Y, Hu G, Liu L, Zhang Y, Jiang N, Zhang M

Neuropsychiatric Disease and Treatment 2026, 22:585445

Published Date: 15 April 2026

Review

Acupuncture for Post-Stroke Cognitive Impairment: Mechanisms and Clinical Evidence (2020–2025)

Chen A, Zhao Z, Zhang Y, Zhang L

Neuropsychiatric Disease and Treatment 2026, 22:593288

Published Date: 14 April 2026

Review

Influence of Neuraxial Anesthesia Technique During Vaginal and Cesarean Delivery and Association with Postpartum Depression: A Narrative Review of Literature

Fagan JJ, Dufour SI, Duet SJ, Downs EM, Siddaiah H, Viswanath O, Shekoohi S, Kaye AD

Neuropsychiatric Disease and Treatment 2026, 22:579920

Published Date: 14 April 2026

Original Research

Risk Factors and Annual Rates of Cognitive Decline in Elderly Mild Cognitive Impairment: A Retrospective Cohort Study

Liu M, Hao Z, Chen J

Neuropsychiatric Disease and Treatment 2026, 22:600786

Published Date: 13 April 2026

Original Research

Diagnosis and Prescribing Patterns of Adult Attention-Deficit ‎Hyperactivity Disorder in a Tertiary Care Hospital in the United ‎Arab Emirates: A Retrospective Study

Sallam M, Albadri R, Khan NN

Neuropsychiatric Disease and Treatment 2026, 22:600491

Published Date: 8 April 2026

Original Research

Associations of Perceived Parenting Practices with Mother–Infant Bonding at 1-Month Postpartum via Adult Attachment, Depression, and Anxiety in Japanese Mothers

Por L, Zain E, Fukui N, Watanabe Y, Hashijiri K, Motegi T, Ogawa M, Boku S

Neuropsychiatric Disease and Treatment 2026, 22:595969

Published Date: 8 April 2026

Original Research

Effects of Introducing the Bbrainklok as a Digital External Memory Aid on Prospective Memory, Apathy and Autonomy in Individuals with Korsakoff’s Syndrome

Smits S, Oudman E, Altgassen M, van Rijswijk L, Postma A

Neuropsychiatric Disease and Treatment 2026, 22:584753

Published Date: 8 April 2026

Original Research

Analysis of the Influencing Factors of Aripiprazole and Risperidone on Bone Mass Health in Patients with Chronic Schizophrenia: A Cross-Sectional Study

Li Z, Wang D, Men T, Fu Z, Shen Y

Neuropsychiatric Disease and Treatment 2026, 22:587771

Published Date: 8 April 2026

Review

Sodium-Glucose Cotransporter-2 Inhibitors in Mood Disorders: A Narrative Review of Mechanisms, Evidence, and Challenges

Guo X, Yang T, Fang Y, Chen J

Neuropsychiatric Disease and Treatment 2026, 22:599108

Published Date: 8 April 2026

Original Research

Correlates of Anti-Toxoplasma IgG Antibodies in Females with Borderline Personality Disorder: A Pilot Cross-Sectional Study

Ociskova M, Prasko J, Belohradova K, Visnovsky J, Vanek J, Genzor S, Sauer P, Latalova K

Neuropsychiatric Disease and Treatment 2026, 22:593736

Published Date: 3 April 2026

Original Research

The Influence of Lifestyle on Cognitive Function and Quality of Life in People with Dementia

Lu H, Rao X, Li N, Liu X, Peng L, Yang B, Liao Q, Lai X

Neuropsychiatric Disease and Treatment 2026, 22:565372

Published Date: 3 April 2026

Original Research

Efficacy and Clinical Relevance of Adjunctive Cariprazine Treatment in Patients with Major Depressive Disorder: Post Hoc Analyses from a Phase III Study

Papakostas GI, Masand PS, Clayton AH, Maletic V, Adams JL, Rekeda L, Singh MK, Kerolous M

Neuropsychiatric Disease and Treatment 2026, 22:561112

Published Date: 1 April 2026

Review

Imbalance of the Brain–Gut–Microbiota Axis in Major Depressive Disorder: From Pathogenesis to Clinical Translation

Wu T, Xing H, Wu T, Xie X, Ji L, Wang W, Zhang X, Zhang Y, Jiang C, Bao T

Neuropsychiatric Disease and Treatment 2026, 22:591429

Published Date: 30 March 2026

Original Research

Altered Habenula Resting-State Functional Connectivity and Spatial Associations with Neurotransmitter Receptor Distribution of Major Depressive Disorder with and without Anhedonia

Luo X, Wu Y, Yuan L, Wang Y, Li J, Xu P, Lian J, Liu X, Shen Z

Neuropsychiatric Disease and Treatment 2026, 22:577735

Published Date: 27 March 2026

Review

The Effect of Sandplay Therapy on Children with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis

Wu X, Zhao X, Meng Y, Huang L, Xie L, Huang S, Yang J, Song Y

Neuropsychiatric Disease and Treatment 2026, 22:579433

Published Date: 26 March 2026

Original Research

Morphometric Similarity Loss and Gray Matter Atrophy Align with Neurotransmitter and Mitochondrial Maps in Drug-Resistant Epilepsy

Zhao J, Gao M, Zhou L, Wan S, Liao N, Yu S, Chen X, Shu H

Neuropsychiatric Disease and Treatment 2026, 22:582833

Published Date: 24 March 2026

Review

A Narrative Review on Rodent Models of Neuropsychopathology Associated with Low Temperature Exposure

Priya V, Ahmad F

Neuropsychiatric Disease and Treatment 2026, 22:571418

Published Date: 21 March 2026

Original Research

The Clinically Meaningful Score Difference and Meaningful Score Regions in Positive and Negative Syndrome Scale Total Score from Post Hoc Analyses of a Phase 3 Pivotal Clinical Trial of Transdermal Asenapine in Patients with Schizophrenia

Citrome L, Czobor P, Komaroff M, Khan M, Hasebe M, Terahara T

Neuropsychiatric Disease and Treatment 2026, 22:562499

Published Date: 21 March 2026

Original Research

The Moderating Role of Social Functioning in the Relationship Between Stigma and Quality of Life in Rural Chinese Patients with Schizophrenia: A Cross-Sectional Study

Wang Q, Fu T, Chen S, Zhang K

Neuropsychiatric Disease and Treatment 2026, 22:592035

Published Date: 20 March 2026

Expert Opinion

The Use of Vagus Nerve Stimulation (VNS) in the Management of Patients with Difficult-to-Treat Major Depressive Disorder (MDD): An Expert Consensus Statement

McAllister-Williams RH, Alva G, Banov M, Conway CR, Cusin C, De Beer JC, Demyttenaere K, Domany Y, Domenech P, Dougherty DD, Dunner DL, Feffer K, George MS, Iosifescu DV, Kavakbasi E, Kraus C, Lehnhardt FG, Lesperance P, McCall WV, Murrough JW, Nahas Z, Nemeroff CB, Quevedo J, Reif-Leonhard C, Riva-Posse P, Rush AJ, Schwartz TL, Stander MP, Williams NR, Zajecka J, Aaronson ST, Baune BT, Sackeim HA

Neuropsychiatric Disease and Treatment 2026, 22:554007

Published Date: 18 March 2026

Original Research

Psychiatric Comorbidity in Chronic Tinnitus: Depression and Anxiety in an Otolaryngology Outpatient Cohort

Sırma E, Dedeoglu S, Toprak SF, Dönmezdil S

Neuropsychiatric Disease and Treatment 2026, 22:589644

Published Date: 18 March 2026

Review

Machine Learning-Based Depression Risk Prediction Models for Older Adults Analyzing From the Perspective of the Health Ecology Model: A Scoping Review

Yang J, Hao X, Sang X, Jiang E, Zhang X

Neuropsychiatric Disease and Treatment 2026, 22:594239

Published Date: 18 March 2026

Original Research

Threshold Effect of Anxiety in the Comorbidity of Depression and Chronic Pain: A Cross-Sectional Study Based on Pain Sensitivity

Liu Y, Cheng J, Gao H, Chen Y, Chen H, Xia Q, Yan J, Li C, Ju P, Zhu C

Neuropsychiatric Disease and Treatment 2026, 22:580711

Published Date: 17 March 2026

Original Research

Co-Administration Treatment in Drug-Naïve Major Depression: Exploratory Real-World Patterns and Predictors in China

Wu J, Zou Y, Zhou J, Meng F, Xiao L

Neuropsychiatric Disease and Treatment 2026, 22:579440

Published Date: 13 March 2026

Original Research

Lurasidone in Schizophrenia Management: A Comprehensive 12-Week Post-Marketing Surveillance Study in Chinese Patients

Wei YM, Yang XD, Wang CS, Wang LL, Deng HL, Sang H, Xue AL, Zhu DM, Li-YM, Liu XJ, Li H, Shen YF

Neuropsychiatric Disease and Treatment 2026, 22:588526

Published Date: 12 March 2026

Original Research

Parameter-Specific Effects of Low-Intensity Transcranial Focused Ultrasound Stimulation on Depression-Like Behaviors in a CUMS Mouse Model

Zhang Y, Zhang Y, Zhang K, Wang L, Huang D, Zhen F, Wang R, An C

Neuropsychiatric Disease and Treatment 2026, 22:586583

Published Date: 12 March 2026

Original Research

Plasma Plasminogen Activator Inhibitor-1 as a Biomarker for Disease Activity and Pharmaco-Response Prediction in Pediatric Epilepsy: A Prospective Cohort Study

Xiao X, Shi XY, Feng J, Zhou XY, Wang ML, Zhang BB, Xu C, Tang JH

Neuropsychiatric Disease and Treatment 2026, 22:583183

Published Date: 12 March 2026

Original Research

Association Between Triglyceride-Glucose Index and Hyperuricemia in Hospitalized Patients with Depression: A Cross-Sectional Study

Zhang L, Guo Y, Wang Z, Wang Y, Yu T, Tian Y

Neuropsychiatric Disease and Treatment 2026, 22:575137

Published Date: 10 March 2026

Original Research

Discriminative Plasma Lipidomic Signatures of Dementia with Lewy Bodies and Alzheimer’s Disease: A Targeted Mass Spectrometry and Machine Learning Approach

Wen L, Zhang Y, Nie Y, Shen H, Qin Q, Qu M

Neuropsychiatric Disease and Treatment 2026, 22:561999

Published Date: 10 March 2026

Original Research

Machine Learning Models for Predicting Antipsychotic Effectiveness and Separate Cost-Effectiveness Analysis in Hospitalized Schizophrenia Patients

Zhang J, Xu Q, Jiang W, Sun D, Peng L

Neuropsychiatric Disease and Treatment 2026, 22:582314

Published Date: 10 March 2026

Review

Inflammatory Cytokines as a Shared Pathophysiological Pathway in Depression and Chronic Insomnia: A Narrative Review of Mechanisms and Clinical Implications

Ren N, Zhang X, Yu Z, Che Y, Zhang Y, Song M, Mao H

Neuropsychiatric Disease and Treatment 2026, 22:585611

Published Date: 5 March 2026

Original Research

Intestinal Flora Reconfiguration via Electroacupuncture: A Strategy to Counteract Depressive-Like Symptoms in Rats

Tan Y, Wu Y, Chen Z, Zhang Z, Huang S, Li Z, Huang Y

Neuropsychiatric Disease and Treatment 2026, 22:565614

Published Date: 4 March 2026

Original Research

Joint Associations of Cardiometabolic Multimorbidity and Depressive Symptoms on Cognitive Function Among Chinese Middle-Aged and Older Adults

Xin Z, Wang L, Wu K, Li X, Guo L, Wang W, Liu J, Jiang B, Kang C, Li Q, Wang X, Lu C

Neuropsychiatric Disease and Treatment 2026, 22:569145

Published Date: 4 March 2026

Original Research

Clinical Utility of Peripheral Non-Enzymatic Antioxidants in Differentiating Major Depressive Disorder from Bipolar Disorder: Associations with Antioxidant Levels, Hospitalization Outcomes, and Antidepressant Efficacy

Dai J, Li Q, Ren B

Neuropsychiatric Disease and Treatment 2026, 22:585769

Published Date: 4 March 2026

Original Research

Exploring the Therapeutic Potential and Mechanism of Qiangzhi Fang in a Rat Model of Tic Disorder with ADHD: Behavioral and Molecular Insights

Lu T, Hu D, Jiang Y, Yan Z

Neuropsychiatric Disease and Treatment 2026, 22:553921

Published Date: 3 March 2026

Review

Clinical Features, Mechanisms, and Management of Anxiety in Youth with Tic Disorders: A Narrative Review

Zhang S, Han F, Chen J, Shen X, Li Y

Neuropsychiatric Disease and Treatment 2026, 22:582875

Published Date: 3 March 2026

Original Research

Benzodiazepines Prescribed to Hospitalized Patients with Major Depressive Disorder: A 3-year Retrospective Observational Study

Fu Y, Jing P, Yin X, Wang H, Zhang Y, Liu X, Zhou C

Neuropsychiatric Disease and Treatment 2026, 22:585720

Published Date: 3 March 2026

Original Research

Clinical Practice Recommendations for Switching from Once-Monthly to Longer-Interval Paliperidone Palmitate Injectable in Schizophrenia Patients: A Modified Delphi Study in China

Ma H, Cai J, Jia F, Zhou J, Zhou B, Zhang W, Ye C, Jia M, Si T

Neuropsychiatric Disease and Treatment 2026, 22:579943

Published Date: 28 February 2026

Review

Exosomes Regulate the NLRP3/Caspase-1/IL-1β Signaling Pathway in Parkinson’s Disease: Mechanisms of Neuroinflammation Modulation and α-Synuclein Propagation

Zhang T, Du H, Wang S

Neuropsychiatric Disease and Treatment 2026, 22:587802

Published Date: 28 February 2026

Study Protocol

Acupuncture for Mild Cognitive Impairment in Vascular Parkinsonism: A Prospective, Randomized, Controlled Trial Protocol

Yu Z, Wang Y, Wang X, Xie Y, Wang Y, Li L, Qin W, Kong Q, Zhang P, Xu J

Neuropsychiatric Disease and Treatment 2026, 22:585695

Published Date: 27 February 2026

Review

Anesthetic Management of Patients for Vagal Nerve Stimulator Placement: A Narrative Review

Henderson NA, Anwar AI, Duet SJ, Rayes Elmalakh S, Shetty V, Shekoohi S, Ahmadzadeh S

Neuropsychiatric Disease and Treatment 2026, 22:579314

Published Date: 26 February 2026

Original Research

Hyperbaric Oxygen Therapy Upregulates Neurotrophic Factors to Ameliorate Post-Stroke Depression: A Randomized Sham-Controlled Trial

Tang M, Gong S, He J, Wu X, Shi M, Yang M, Shi L, Huang L, Li L, Zhou D, Zhao Y

Neuropsychiatric Disease and Treatment 2026, 22:573494

Published Date: 26 February 2026

Original Research

Predicting Post-Stroke Depression Risk in Elderly Patients Based on Machine Learning: A Retrospective Cohort Study Integrating Neuroimaging and Psychosocial Variables

Zhang L, Yu P, Yang L, Zhong Z

Neuropsychiatric Disease and Treatment 2026, 22:580089

Published Date: 24 February 2026

Original Research

Postsurgical Seizure Outcome for Epilepsy Patients According to Histopathological Diagnosis: A Single-Center Experience

Chen R, Hong ST, Wu SY, Jiang XQ, Su XJ, Zhang YQ, Mei Z, Lin H, Lin H, Hu XQ, Lin YX, Wang F

Neuropsychiatric Disease and Treatment 2026, 22:585977

Published Date: 24 February 2026

Review

Central Stimulants in a Stressed Brain: Evidence Synthesis of Benefits, Burnout Risk, and Clinical Safeguards in ADHD

Amiri D, Briziarelli L, Shah SJ, Amiri S, Madani N, Karlsson B

Neuropsychiatric Disease and Treatment 2026, 22:567670

Published Date: 24 February 2026

Original Research

Stem Cells from Human Exfoliated Deciduous Teeth Attenuate Depression-Like Behaviors in CUMS Rats by Suppressing Neuroinflammation and Enhancing Synaptic Plasticity

Yu F, Gao Y, Du X, Liu S, Xu Y

Neuropsychiatric Disease and Treatment 2026, 22:586668

Published Date: 24 February 2026

Original Research

Disease Awareness, Care-Seeking Behavior, and Symptom Burden Among Japanese Patients with Generalized Anxiety Disorder: Results from a Web-Based Questionnaire of Clinical Trial Participants

Nomoto K, Otsubo T, Misago R, Higa S

Neuropsychiatric Disease and Treatment 2026, 22:582812

Published Date: 24 February 2026

Original Research

Association Between Clinical Symptoms and Inflammatory Markers in First-Episode Unmedicated Patients with Major Depressive Disorder

Guan H, Sun J, Cheng J, Chen L, Zhao Y, Yang X, Wang D, Zhang X

Neuropsychiatric Disease and Treatment 2026, 22:582480

Published Date: 23 February 2026

Original Research

Childhood Sexual Abuse and Its Association with Clinical and Psychological Features in Patients with Eating Disorders in China

Chen C, Zhang X, Jiang H, Li X, Kong Q, Si T, Zhang D

Neuropsychiatric Disease and Treatment 2026, 22:554645

Published Date: 23 February 2026

Review

Depression and Gastrointestinal Health Abnormalities: Treatment Approaches from the Perspective of Traditional Chinese Medicine

Lu K, Tang A, Liu Y, Li L, Fang R, Zhang S, Chen Y, Cao F

Neuropsychiatric Disease and Treatment 2026, 22:584034

Published Date: 20 February 2026

Original Research

White Matter Integrity in General Paresis: An Exploratory Tract-Based Spatial Statistical Analysis

Chen H, Li S, Xing YX, Xie RM, Xue M, Li JJ

Neuropsychiatric Disease and Treatment 2026, 22:569932

Published Date: 19 February 2026

Review

Functional MRI in Multiple System Atrophy: A Promising Biomarker for Clinical Applications

Xiao S, Ding Y, Weiss A, Cai L, Wang X, Geng X

Neuropsychiatric Disease and Treatment 2026, 22:566720

Published Date: 18 February 2026

Review

Ferroptosis in Cerebral Ischemia/Reperfusion Injury: Mechanistic Drivers and Therapeutic Frontiers

Song C, Liu Z, Tang J, Huang Y

Neuropsychiatric Disease and Treatment 2026, 22:580170

Published Date: 18 February 2026

Original Research

Development and Validation of a Machine Learning Model for Predicting Osteoporosis in Patients with Parkinson’s Disease

Liang Y, Yin Y, Zhen K, Lin H, Yu G, Li X

Neuropsychiatric Disease and Treatment 2026, 22:582787

Published Date: 17 February 2026

Original Research

Real-World Assessment of Transcranial Direct Current Stimulation (tDCS) Combined with Sertraline in the Treatment of Depression in Vietnam

Do TX, Bui HQ, Dinh HV, Nguyen LV, Pham TT, Nguyen DT, Nguyen DT, Huynh LN, Pham TQ, Pham TN, Tran TN, Nguyen XT

Neuropsychiatric Disease and Treatment 2026, 22:567022

Published Date: 12 February 2026

Original Research

The Association of Thyroid Function on Cognition and Neuropsychiatric Symptoms in Patients with Cognitive Impairment

Lin YR, Chang MC, Wang WF, Tung YC, Jhang KM

Neuropsychiatric Disease and Treatment 2026, 22:575834

Published Date: 11 February 2026

Review

Review and Update of Anesthetic Management for Electroconvulsive Therapy: A Narrative Review

Singh A, Davis F, Anwar AI, Hirsch JD, Barrie SA, Tirumala S, Shekoohi S, Ahmadzadeh S

Neuropsychiatric Disease and Treatment 2026, 22:563824

Published Date: 8 February 2026

Review

Autism Spectrum Disorder in the Genomic Era: A Comprehensive Review of Etiology, Precision Diagnostics, Clinical Outcomes, and Emerging Gene-Editing Therapies

Xiong N, Yu Z

Neuropsychiatric Disease and Treatment 2026, 22:585060

Published Date: 7 February 2026

Review

Association Between Depression and the Risk of Hyperemesis Gravidarum: A Systematic Review and Meta-Analysis

Xu J, Qin Z, Wang X, Chen J, Zhuang L

Neuropsychiatric Disease and Treatment 2026, 22:567778

Published Date: 5 February 2026

Original Research

Comparative Evaluation of CT and MRI in Detecting Intracranial and Extracranial Manifestations of Tuberous Sclerosis Complex

He J, Deng LH, Wang K, Deng C, Lai YM, Zeng Y

Neuropsychiatric Disease and Treatment 2026, 22:558051

Published Date: 4 February 2026

Original Research

Vortioxetine in Subgroups of Patients with Major Depressive Disorder and Early-Stage Dementia: Further Results from the MEMORY Study

Grande I, Schmidt SN, Reines E, Christensen MC

Neuropsychiatric Disease and Treatment 2026, 22:549106

Published Date: 2 February 2026

Retraction

Mechanism of Autophagy Regulation in MPTP-Induced PD Mice via the mTOR Signaling Pathway by Echinacoside [Retraction]

Zhang ZN, Hui Z, Chen C, Liang Y, Tang LL, Wang SL, Xu CC, Yang H, Zhao Y, Zhang JS

Neuropsychiatric Disease and Treatment 2026, 22:599823

Published Date: 2 February 2026

Original Research

The Effect of miR-1273d Between Chronic Childhood Stress and Positive Symptoms in Schizophrenia: A Preliminary Mediation Analysis

Kong L, Zheng J, Qiang L, Chen S

Neuropsychiatric Disease and Treatment 2026, 22:562131

Published Date: 31 January 2026

Original Research

Association Between Glymphatic Dysfunction and Anxiety in Parkinson’s Disease: Insights from DTI-ALPS and Choroid Plexus Volume

Sa L, Li S, Chen L, Wang J, Wang Y, Cheng C, Xin C, Zhang S, Ding F, Wang B

Neuropsychiatric Disease and Treatment 2026, 22:568398

Published Date: 27 January 2026

Original Research

Systems Pharmacology and Multi-Omics Reveal Synergistic Antidepressant Mechanisms of Radix Bupleurum–Radix Paeoniae Alba via Oxidative Stress, Neuroimmune Balance, and Circadian Rhythm

Zhang H, Wang W, Zhang S, Li X, Li W, Ji C

Neuropsychiatric Disease and Treatment 2026, 22:560271

Published Date: 24 January 2026

Original Research

Psychosocial and Biological Factors Associated with Non-Suicidal Self-Injury in Chinese Child and Adolescent Inpatients with Major Depressive Disorder

Liu C, Zhu XY, Shi YN, Wang PJ, Jiang WH, Zhou J, Qiu JC, Chen PF, Ding JC, Yan Q, Ding YQ

Neuropsychiatric Disease and Treatment 2026, 22:570371

Published Date: 24 January 2026

Review

The Effectiveness of Non-Pharmacological Interventions in Treating Adolescents and Young Adults with Neuropsychiatric Symptoms of Long COVID: A Systematic Review and Meta-Analysis

Choi S, Huda MN, John JR, Eapen V

Neuropsychiatric Disease and Treatment 2026, 22:570223

Published Date: 23 January 2026

Original Research

Z-Drug Use and All-Cause Mortality: A Meta-Analysis of Observational Cohort Studies

Park JY, Park HJ, Ko HJ, Kim AS, Song JE, Hong HE

Neuropsychiatric Disease and Treatment 2026, 22:556191

Published Date: 23 January 2026

Original Research

Serum Homocysteine as a Potential Dynamic Biomarker for Staging and Monitoring Progression in Alzheimer’s Disease

Wu C, Wu C, Yin X, Zhong C

Neuropsychiatric Disease and Treatment 2026, 22:553269

Published Date: 21 January 2026

Original Research

How to Predict the Onset of Anxiety and Depression in Pediatric Residents? -- A Survey From China

Liu X, Song C, Li H, Jiang Z, Feng L

Neuropsychiatric Disease and Treatment 2026, 22:573146

Published Date: 21 January 2026

Original Research

Predictive Factors of Low HDL-C in Patients with Schizophrenia

Huang YC, Hung CF, Lee Y, Lin PY, Wang LJ

Neuropsychiatric Disease and Treatment 2026, 22:568841

Published Date: 20 January 2026

Original Research

Prevalence and Clinical Correlates of Anxiety in Chinese Outpatient Population with Somatic Symptom Disorder

Liao H, Fang J, Zhong Y, Li Y, Zhang J, Tang H

Neuropsychiatric Disease and Treatment 2026, 22:548264

Published Date: 20 January 2026

Original Research

Flaxseed Supplementation Confers Resilience to Stress-Induced Depression-Like Behaviors via GDNF Epigenetic Modulation in the Ventral Tegmental Area of Rats

Lu Q, Chen X, Zhou X, Zhang R, Deng X, Zhu X, Zhang Y

Neuropsychiatric Disease and Treatment 2026, 22:562758

Published Date: 20 January 2026

Original Research

Establishment and Validation of Machine Learning Model for Predicting Suicide Risk in Patients with Major Depressive Disorder

Tan H, Wang Z, Ma J, Wang Z, Zhang X

Neuropsychiatric Disease and Treatment 2026, 22:561526

Published Date: 19 January 2026

Original Research

Elucidating Biological Links in Autism Spectrum Disorder: From Blood-Based Risk Factor Identification to a Validated Nomogram for Early Risk Stratification

Lin L, Wang X, Wang P, Wang Q, Sun J, Li H, Cong F

Neuropsychiatric Disease and Treatment 2026, 22:568119

Published Date: 17 January 2026

Original Research

Sertraline for the Treatment of Major Depressive Disorder in the US: Effectiveness and Acceptability in Real-World Practice

Correll CU, Purushottamahanti P, Subramaniam K, Bayan B, Cook JP, Palmer EO, Yeow J, Lipunova N

Neuropsychiatric Disease and Treatment 2026, 22:563433

Published Date: 15 January 2026

Original Research

Effect of Venlafaxine on Inflammatory Level in Patients with Depression

Zhang H, Huang N, Ma X, Liu Y

Neuropsychiatric Disease and Treatment 2026, 22:543189

Published Date: 14 January 2026

Review

Targeting Programmed Cell Death in Depression: A Review of Traditional Chinese Medicine Interventions Based on Preclinical Evidence

Jia H, Wu M, Teng L, Song W, Li X, Wang B, Huang Y, Kang X, Zhu L

Neuropsychiatric Disease and Treatment 2026, 22:562047

Published Date: 14 January 2026

Review

Epigenetic Changes in Alzheimer’s Disease and Interventions for Therapy

Xu M, Xiong L, Qin Z, Yu X, Chen T, Zhang X, Jin M, Wang L, Cai L, Wei Y, Liu H, Wang C, Hu H, Zou Z

Neuropsychiatric Disease and Treatment 2026, 22:576404

Published Date: 13 January 2026

Original Research

Identifying Physiological and Cognitive Indicators of Subthreshold Depression and Major Depressive Disorder Progression Risk

Shimizu A, Yokoyama S, Fermin ASR, Mitsuyama Y, Mizoi K, Yoshimoto J, Furukawa TA, Takagaki K, Okamoto Y, Okamoto Y, Okada G

Neuropsychiatric Disease and Treatment 2026, 22:526034

Published Date: 9 January 2026

Review

Traditional Chinese Medicine Ameliorates Depression via the Gut-Brain Axis: A Review Focus on NLRP3/TLR4-Mediated Inflammatory Pathways and Gut Microbiota Modulation

Che L, Xie J, Xia C, Yu Q

Neuropsychiatric Disease and Treatment 2026, 22:579710

Published Date: 8 January 2026