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Neuropsychiatric Disease and Treatment

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ISSN: 1178-2021

Archive: Volume 22, 2026

Clinical Benefit and Risk Profile of TV-46000 for Patients with Schizophrenia as Assessed by Number Needed to Treat and Number Needed to Harm

Citrome L, Franzenburg KR, Suett M, Tohami O, Sharon N, Jehassi A, Harary E, Yu D, Correll CU

Neuropsychiatric Disease and Treatment 2026, 22:534730

Published Date: 8 May 2026

Efficacy and Safety of Escitalopram for Major Depressive Disorder in Children and Adolescents: A Systematic Review and Meta-Analysis with Age-Specific Findings

Maneeton B, Maneeton N, Pojanapotha P, Putthisri S, Oon-arom A, Karawekpanyawong N, Kawilapat S, Maneeton P, Srichan K

Neuropsychiatric Disease and Treatment 2026, 22:595606

Published Date: 5 May 2026

Peripheral Blood Regulatory T Cells and IL-6 are Associated with Cognitive Impairment After Acute Ischemic Stroke

Chang Y, Zhang X, Yu C, Zhu L, Sun S, Sun Z

Neuropsychiatric Disease and Treatment 2026, 22:590109

Published Date: 1 May 2026

Optimizing Identification and Management of Depression in Neurological Diseases: A Narrative Review and Expert Perspective

Bartova L, Beuster ML, Bonetti B, Maina G, Morgado P, Nyberg J

Neuropsychiatric Disease and Treatment 2026, 22:575685

Published Date: 1 May 2026

Association Between Frontotemporal Atrophy and Cognitive Impairment in Patients with Schizophrenia Based on Computed Tomography Imaging

Wang Y, Yang J, Ye Y, Lu L, Wang H, Guo P, Hou N, Huang X, Li C

Neuropsychiatric Disease and Treatment 2026, 22:602462

Published Date: 30 April 2026

Long-Term Effectiveness and Safety of LCIG in Romania. 3-year Results from a Prospective, Observational Study (DUOGLOBE)

Szasz JA, Constantin VA, Jianu DC, Dan TF, Dulamea AO, Sabau M, Vasile MT, Bergmann L, Popescu D, Simu MA

Neuropsychiatric Disease and Treatment 2026, 22:564900

Published Date: 28 April 2026

An Open-Label, Single-Arm Trial of Transcranial and Intranasal Photobiomodulation in Patients with Schizophrenia: A Study Protocol

Yamada R, Izumi S, Oba MS, Noda T, Stickley A, Sumiyoshi T

Neuropsychiatric Disease and Treatment 2026, 22:585770

Published Date: 21 April 2026

Neurocognitive and Psychiatric Outcomes Following Mild to Moderate COVID-19: A Longitudinal Comparison of Alpha/Delta and Omicron Variants

Lynch ST, Dornbush R, Aftab S, Mansour R, Libretti A, Shahar S, Bilal A, Klepacz L, Ferrando SJ

Neuropsychiatric Disease and Treatment 2026, 22:594322

Published Date: 18 April 2026

Wavelet Entropy Analysis of EEG Signals During Wake and Sleep in Patients with Alzheimer’s Disease: A Pilot Study

Tong Y, Hu G, Liu L, Zhang Y, Jiang N, Zhang M

Neuropsychiatric Disease and Treatment 2026, 22:585445

Published Date: 15 April 2026

Influence of Neuraxial Anesthesia Technique During Vaginal and Cesarean Delivery and Association with Postpartum Depression: A Narrative Review of Literature

Fagan JJ, Dufour SI, Duet SJ, Downs EM, Siddaiah H, Viswanath O, Shekoohi S, Kaye AD

Neuropsychiatric Disease and Treatment 2026, 22:579920

Published Date: 14 April 2026

Associations of Perceived Parenting Practices with Mother–Infant Bonding at 1-Month Postpartum via Adult Attachment, Depression, and Anxiety in Japanese Mothers

Por L, Zain E, Fukui N, Watanabe Y, Hashijiri K, Motegi T, Ogawa M, Boku S

Neuropsychiatric Disease and Treatment 2026, 22:595969

Published Date: 8 April 2026

Correlates of Anti-Toxoplasma IgG Antibodies in Females with Borderline Personality Disorder: A Pilot Cross-Sectional Study

Ociskova M, Prasko J, Belohradova K, Visnovsky J, Vanek J, Genzor S, Sauer P, Latalova K

Neuropsychiatric Disease and Treatment 2026, 22:593736

Published Date: 3 April 2026

The Influence of Lifestyle on Cognitive Function and Quality of Life in People with Dementia

Lu H, Rao X, Li N, Liu X, Peng L, Yang B, Liao Q, Lai X

Neuropsychiatric Disease and Treatment 2026, 22:565372

Published Date: 3 April 2026

Efficacy and Clinical Relevance of Adjunctive Cariprazine Treatment in Patients with Major Depressive Disorder: Post Hoc Analyses from a Phase III Study

Papakostas GI, Masand PS, Clayton AH, Maletic V, Adams JL, Rekeda L, Singh MK, Kerolous M

Neuropsychiatric Disease and Treatment 2026, 22:561112

Published Date: 1 April 2026

Imbalance of the Brain–Gut–Microbiota Axis in Major Depressive Disorder: From Pathogenesis to Clinical Translation

Wu T, Xing H, Wu T, Xie X, Ji L, Wang W, Zhang X, Zhang Y, Jiang C, Bao T

Neuropsychiatric Disease and Treatment 2026, 22:591429

Published Date: 30 March 2026

The Effect of Sandplay Therapy on Children with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis

Wu X, Zhao X, Meng Y, Huang L, Xie L, Huang S, Yang J, Song Y

Neuropsychiatric Disease and Treatment 2026, 22:579433

Published Date: 26 March 2026

Morphometric Similarity Loss and Gray Matter Atrophy Align with Neurotransmitter and Mitochondrial Maps in Drug-Resistant Epilepsy

Zhao J, Gao M, Zhou L, Wan S, Liao N, Yu S, Chen X, Shu H

Neuropsychiatric Disease and Treatment 2026, 22:582833

Published Date: 24 March 2026

The Use of Vagus Nerve Stimulation (VNS) in the Management of Patients with Difficult-to-Treat Major Depressive Disorder (MDD): An Expert Consensus Statement

McAllister-Williams RH, Alva G, Banov M, Conway CR, Cusin C, De Beer JC, Demyttenaere K, Domany Y, Domenech P, Dougherty DD, Dunner DL, Feffer K, George MS, Iosifescu DV, Kavakbasi E, Kraus C, Lehnhardt FG, Lesperance P, McCall WV, Murrough JW, Nahas Z, Nemeroff CB, Quevedo J, Reif-Leonhard C, Riva-Posse P, Rush AJ, Schwartz TL, Stander MP, Williams NR, Zajecka J, Aaronson ST, Baune BT, Sackeim HA

Neuropsychiatric Disease and Treatment 2026, 22:554007

Published Date: 18 March 2026

Psychiatric Comorbidity in Chronic Tinnitus: Depression and Anxiety in an Otolaryngology Outpatient Cohort

Sırma E, Dedeoglu S, Toprak SF, Dönmezdil S

Neuropsychiatric Disease and Treatment 2026, 22:589644

Published Date: 18 March 2026

Threshold Effect of Anxiety in the Comorbidity of Depression and Chronic Pain: A Cross-Sectional Study Based on Pain Sensitivity

Liu Y, Cheng J, Gao H, Chen Y, Chen H, Xia Q, Yan J, Li C, Ju P, Zhu C

Neuropsychiatric Disease and Treatment 2026, 22:580711

Published Date: 17 March 2026

Lurasidone in Schizophrenia Management: A Comprehensive 12-Week Post-Marketing Surveillance Study in Chinese Patients

Wei YM, Yang XD, Wang CS, Wang LL, Deng HL, Sang H, Xue AL, Zhu DM, Li-YM, Liu XJ, Li H, Shen YF

Neuropsychiatric Disease and Treatment 2026, 22:588526

Published Date: 12 March 2026

Parameter-Specific Effects of Low-Intensity Transcranial Focused Ultrasound Stimulation on Depression-Like Behaviors in a CUMS Mouse Model

Zhang Y, Zhang Y, Zhang K, Wang L, Huang D, Zhen F, Wang R, An C

Neuropsychiatric Disease and Treatment 2026, 22:586583

Published Date: 12 March 2026

Intestinal Flora Reconfiguration via Electroacupuncture: A Strategy to Counteract Depressive-Like Symptoms in Rats

Tan Y, Wu Y, Chen Z, Zhang Z, Huang S, Li Z, Huang Y

Neuropsychiatric Disease and Treatment 2026, 22:565614

Published Date: 4 March 2026

Joint Associations of Cardiometabolic Multimorbidity and Depressive Symptoms on Cognitive Function Among Chinese Middle-Aged and Older Adults

Xin Z, Wang L, Wu K, Li X, Guo L, Wang W, Liu J, Jiang B, Kang C, Li Q, Wang X, Lu C

Neuropsychiatric Disease and Treatment 2026, 22:569145

Published Date: 4 March 2026

Benzodiazepines Prescribed to Hospitalized Patients with Major Depressive Disorder: A 3-year Retrospective Observational Study

Fu Y, Jing P, Yin X, Wang H, Zhang Y, Liu X, Zhou C

Neuropsychiatric Disease and Treatment 2026, 22:585720

Published Date: 3 March 2026

Acupuncture for Mild Cognitive Impairment in Vascular Parkinsonism: A Prospective, Randomized, Controlled Trial Protocol

Yu Z, Wang Y, Wang X, Xie Y, Wang Y, Li L, Qin W, Kong Q, Zhang P, Xu J

Neuropsychiatric Disease and Treatment 2026, 22:585695

Published Date: 27 February 2026

Anesthetic Management of Patients for Vagal Nerve Stimulator Placement: A Narrative Review

Henderson NA, Anwar AI, Duet SJ, Rayes Elmalakh S, Shetty V, Shekoohi S, Ahmadzadeh S

Neuropsychiatric Disease and Treatment 2026, 22:579314

Published Date: 26 February 2026

Hyperbaric Oxygen Therapy Upregulates Neurotrophic Factors to Ameliorate Post-Stroke Depression: A Randomized Sham-Controlled Trial

Tang M, Gong S, He J, Wu X, Shi M, Yang M, Shi L, Huang L, Li L, Zhou D, Zhao Y

Neuropsychiatric Disease and Treatment 2026, 22:573494

Published Date: 26 February 2026

Postsurgical Seizure Outcome for Epilepsy Patients According to Histopathological Diagnosis: A Single-Center Experience

Chen R, Hong ST, Wu SY, Jiang XQ, Su XJ, Zhang YQ, Mei Z, Lin H, Lin H, Hu XQ, Lin YX, Wang F

Neuropsychiatric Disease and Treatment 2026, 22:585977

Published Date: 24 February 2026

Central Stimulants in a Stressed Brain: Evidence Synthesis of Benefits, Burnout Risk, and Clinical Safeguards in ADHD

Amiri D, Briziarelli L, Shah SJ, Amiri S, Madani N, Karlsson B

Neuropsychiatric Disease and Treatment 2026, 22:567670

Published Date: 24 February 2026

Association Between Clinical Symptoms and Inflammatory Markers in First-Episode Unmedicated Patients with Major Depressive Disorder

Guan H, Sun J, Cheng J, Chen L, Zhao Y, Yang X, Wang D, Zhang X

Neuropsychiatric Disease and Treatment 2026, 22:582480

Published Date: 23 February 2026

Childhood Sexual Abuse and Its Association with Clinical and Psychological Features in Patients with Eating Disorders in China

Chen C, Zhang X, Jiang H, Li X, Kong Q, Si T, Zhang D

Neuropsychiatric Disease and Treatment 2026, 22:554645

Published Date: 23 February 2026

Depression and Gastrointestinal Health Abnormalities: Treatment Approaches from the Perspective of Traditional Chinese Medicine

Lu K, Tang A, Liu Y, Li L, Fang R, Zhang S, Chen Y, Cao F

Neuropsychiatric Disease and Treatment 2026, 22:584034

Published Date: 20 February 2026

White Matter Integrity in General Paresis: An Exploratory Tract-Based Spatial Statistical Analysis

Chen H, Li S, Xing YX, Xie RM, Xue M, Li JJ

Neuropsychiatric Disease and Treatment 2026, 22:569932

Published Date: 19 February 2026

Functional MRI in Multiple System Atrophy: A Promising Biomarker for Clinical Applications

Xiao S, Ding Y, Weiss A, Cai L, Wang X, Geng X

Neuropsychiatric Disease and Treatment 2026, 22:566720

Published Date: 18 February 2026

Real-World Assessment of Transcranial Direct Current Stimulation (tDCS) Combined with Sertraline in the Treatment of Depression in Vietnam

Do TX, Bui HQ, Dinh HV, Nguyen LV, Pham TT, Nguyen DT, Nguyen DT, Huynh LN, Pham TQ, Pham TN, Tran TN, Nguyen XT

Neuropsychiatric Disease and Treatment 2026, 22:567022

Published Date: 12 February 2026

The Association of Thyroid Function on Cognition and Neuropsychiatric Symptoms in Patients with Cognitive Impairment

Lin YR, Chang MC, Wang WF, Tung YC, Jhang KM

Neuropsychiatric Disease and Treatment 2026, 22:575834

Published Date: 11 February 2026

Review and Update of Anesthetic Management for Electroconvulsive Therapy: A Narrative Review

Singh A, Davis F, Anwar AI, Hirsch JD, Barrie SA, Tirumala S, Shekoohi S, Ahmadzadeh S

Neuropsychiatric Disease and Treatment 2026, 22:563824

Published Date: 8 February 2026

Comparative Evaluation of CT and MRI in Detecting Intracranial and Extracranial Manifestations of Tuberous Sclerosis Complex

He J, Deng LH, Wang K, Deng C, Lai YM, Zeng Y

Neuropsychiatric Disease and Treatment 2026, 22:558051

Published Date: 4 February 2026

Mechanism of Autophagy Regulation in MPTP-Induced PD Mice via the mTOR Signaling Pathway by Echinacoside [Retraction]

Zhang ZN, Hui Z, Chen C, Liang Y, Tang LL, Wang SL, Xu CC, Yang H, Zhao Y, Zhang JS

Neuropsychiatric Disease and Treatment 2026, 22:599823

Published Date: 2 February 2026

Association Between Glymphatic Dysfunction and Anxiety in Parkinson’s Disease: Insights from DTI-ALPS and Choroid Plexus Volume

Sa L, Li S, Chen L, Wang J, Wang Y, Cheng C, Xin C, Zhang S, Ding F, Wang B

Neuropsychiatric Disease and Treatment 2026, 22:568398

Published Date: 27 January 2026

Psychosocial and Biological Factors Associated with Non-Suicidal Self-Injury in Chinese Child and Adolescent Inpatients with Major Depressive Disorder

Liu C, Zhu XY, Shi YN, Wang PJ, Jiang WH, Zhou J, Qiu JC, Chen PF, Ding JC, Yan Q, Ding YQ

Neuropsychiatric Disease and Treatment 2026, 22:570371

Published Date: 24 January 2026

Z-Drug Use and All-Cause Mortality: A Meta-Analysis of Observational Cohort Studies

Park JY, Park HJ, Ko HJ, Kim AS, Song JE, Hong HE

Neuropsychiatric Disease and Treatment 2026, 22:556191

Published Date: 23 January 2026

How to Predict the Onset of Anxiety and Depression in Pediatric Residents? -- A Survey From China

Liu X, Song C, Li H, Jiang Z, Feng L

Neuropsychiatric Disease and Treatment 2026, 22:573146

Published Date: 21 January 2026

Predictive Factors of Low HDL-C in Patients with Schizophrenia

Huang YC, Hung CF, Lee Y, Lin PY, Wang LJ

Neuropsychiatric Disease and Treatment 2026, 22:568841

Published Date: 20 January 2026

Prevalence and Clinical Correlates of Anxiety in Chinese Outpatient Population with Somatic Symptom Disorder

Liao H, Fang J, Zhong Y, Li Y, Zhang J, Tang H

Neuropsychiatric Disease and Treatment 2026, 22:548264

Published Date: 20 January 2026

Sertraline for the Treatment of Major Depressive Disorder in the US: Effectiveness and Acceptability in Real-World Practice

Correll CU, Purushottamahanti P, Subramaniam K, Bayan B, Cook JP, Palmer EO, Yeow J, Lipunova N

Neuropsychiatric Disease and Treatment 2026, 22:563433

Published Date: 15 January 2026

Effect of Venlafaxine on Inflammatory Level in Patients with Depression

Zhang H, Huang N, Ma X, Liu Y

Neuropsychiatric Disease and Treatment 2026, 22:543189

Published Date: 14 January 2026

Targeting Programmed Cell Death in Depression: A Review of Traditional Chinese Medicine Interventions Based on Preclinical Evidence

Jia H, Wu M, Teng L, Song W, Li X, Wang B, Huang Y, Kang X, Zhu L

Neuropsychiatric Disease and Treatment 2026, 22:562047

Published Date: 14 January 2026

Epigenetic Changes in Alzheimer’s Disease and Interventions for Therapy

Xu M, Xiong L, Qin Z, Yu X, Chen T, Zhang X, Jin M, Wang L, Cai L, Wei Y, Liu H, Wang C, Hu H, Zou Z

Neuropsychiatric Disease and Treatment 2026, 22:576404

Published Date: 13 January 2026

Identifying Physiological and Cognitive Indicators of Subthreshold Depression and Major Depressive Disorder Progression Risk

Shimizu A, Yokoyama S, Fermin ASR, Mitsuyama Y, Mizoi K, Yoshimoto J, Furukawa TA, Takagaki K, Okamoto Y, Okamoto Y, Okada G

Neuropsychiatric Disease and Treatment 2026, 22:526034

Published Date: 9 January 2026