Pragmatic and Observational Researchhttps://www.dovepress.com/feed/journal/95New articles released by Dove Press for Pragmatic and Observational Researchen-us2026, Dove Pressangela@dovepress.com (Angela Jones)Dove Press Pragmatic and Observational ResearchPragmatic and Observational Researchhttps://www.dovepress.com/feed/journal/95https://www.dovepress.com/assets/img/addon/rss-banner.jpg140140Development and Internal Validation of a Prediction Model for Major Cardiovascular and Respiratory Events in Chronic Obstructive Pulmonary Disease: Nationwide Primary Care Electronic Medical Records Cohort Studyhttps://www.dovepress.com/development-and-internal-validation-of-a-prediction-model-for-major-ca-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchTue, 10 Mar 2026 20:25:00 +1300https://doi.org/10.2147/POR.S551291The Potential Impact of GLP-1 Receptor Agonists on Exacerbation Risk in Patients with COPD and Type 2 Diabetes: A Real-World Population-Based Observational Studyhttps://www.dovepress.com/the-potential-impact-of-glp-1-receptor-agonists-on-exacerbation-risk-i-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchFri, 30 Jan 2026 00:00:00 +1300https://doi.org/10.2147/POR.S550543Validity of Using Prescription Medications to Classify Disease – A Retrospective Observational Study Using Routinely Collected Electronic Health Records from the UKhttps://www.dovepress.com/validity-of-using-prescription-medications-to-classify-disease--a-retr-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchThu, 15 Jan 2026 00:00:00 +1300https://doi.org/10.2147/POR.S553011Relapse Predictors of Idiopathic Retroperitoneal Fibrosis: A Long-Term Cohort Studyhttps://www.dovepress.com/relapse-predictors-of-idiopathic-retroperitoneal-fibrosis-a-long-term--peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchSat, 20 Dec 2025 02:30:00 +1300https://doi.org/10.2147/POR.S562743INSIGHTS Asthma Pragmatic Registry – A Pragmatic Approach to High-Validity Real-World Evidence for Asthmahttps://www.dovepress.com/insights-asthma-pragmatic-registry--a-pragmatic-approach-to-high-valid-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchThu, 18 Dec 2025 17:00:00 +1300https://doi.org/10.2147/POR.S517474Derivation and Definitions of Clinical Study Variables for Multiple Long Term Conditions in Patients with Chronic Obstructive Pulmonary Disease: Protocol for a Modified Delphi Methods and Consensus Study on Behalf of the International Cardiovascular and Respiratory Alliancehttps://www.dovepress.com/derivation-and-definitions-of-clinical-study-variables-for-multiple-lo-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchFri, 12 Dec 2025 00:35:00 +1300https://doi.org/10.2147/POR.S550533Evaluation of Disease Modifying Therapies and Prognostic Factors Affecting Multiple Sclerosis Progression in a Local Centre of Hong Konghttps://www.dovepress.com/evaluation-of-disease-modifying-therapies-and-prognostic-factors-affec-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchTue, 02 Dec 2025 04:25:00 +1300https://doi.org/10.2147/POR.S556886One Year Risk Prediction Model for Cardiovascular Disease for Adults with Asthma in Englandhttps://www.dovepress.com/one-year-risk-prediction-model-for-cardiovascular-disease-for-adults-w-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchSat, 15 Nov 2025 16:00:00 +1300https://doi.org/10.2147/POR.S520056Real-World Treatment Patterns and Overall Survival (OS) of Patients with Metastatic Castration-Resistant Prostate Cancer in Italyhttps://www.dovepress.com/real-world-treatment-patterns-and-overall-survival-os-of-patients-with-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchTue, 11 Nov 2025 03:50:00 +1300https://doi.org/10.2147/POR.S539229Clinical Outcomes of Ablation for Persistent Atrial Fibrillation with Zero or Minimal Fluoroscopyhttps://www.dovepress.com/clinical-outcomes-of-ablation-for-persistent-atrial-fibrillation-with--peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchTue, 23 Sep 2025 18:10:00 +1200https://doi.org/10.2147/POR.S526839Expert Perspectives on Next Generation Health Guidelines: How to Integrate RWE in EBMhttps://www.dovepress.com/expert-perspectives-on-next-generation-health-guidelines-how-to-integr-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchThu, 11 Sep 2025 14:10:00 +1200https://doi.org/10.2147/POR.S487342Evaluating the Potential of Prevalent New User Design as an Alternative When New User Design is Impracticalhttps://www.dovepress.com/evaluating-the-potential-of-prevalent-new-user-design-as-an-alternativ-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchThu, 31 Jul 2025 02:35:00 +1200https://doi.org/10.2147/POR.S517514Association of Frequent Short-Acting Beta-Agonist Inhaler Prescriptions with Acute Cardiovascular Eventshttps://www.dovepress.com/association-of-frequent-short-acting-beta-agonist-inhaler-prescription-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchFri, 25 Jul 2025 21:32:00 +1200https://doi.org/10.2147/POR.S522323Mapping EQ-5D-5L Score From SGRQ in Patients with Asthma and/or COPD in NOVELTYhttps://www.dovepress.com/mapping-eq-5d-5l-score-from-sgrq-in-patients-with-asthma-andor-copd-in-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchWed, 04 Jun 2025 03:50:00 +1200https://doi.org/10.2147/POR.S508814Comprehensive Description of an Automated Drug Dispensing System Databasehttps://www.dovepress.com/comprehensive-description-of-an-automated-drug-dispensing-system-datab-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchTue, 08 Apr 2025 17:45:00 +1200https://doi.org/10.2147/POR.S488210Steroidal Mineralocorticoid Receptor Antagonist Side Effects and Reasons for Discontinuation: A Patient Survey (RELICS-PS)https://www.dovepress.com/steroidal-mineralocorticoid-receptor-antagonist-side-effects-and-reaso-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchThu, 03 Apr 2025 23:05:00 +1300https://doi.org/10.2147/POR.S489802Shifting from Traditional to Pragmatic Randomized Controlled Trials: Insights and Lessons Learned from the Toddler Oral Health Interventionhttps://www.dovepress.com/shifting-from-traditional-to-pragmatic-randomized-controlled-trials-in-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchSat, 29 Mar 2025 21:30:00 +1300https://doi.org/10.2147/POR.S493195Predicting Risk of Morbidities Associated with Oral Corticosteroid Prescription for Asthmahttps://www.dovepress.com/predicting-risk-of-morbidities-associated-with-oral-corticosteroid-pre-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchTue, 25 Mar 2025 17:05:00 +1300https://doi.org/10.2147/POR.S484146Better Understanding Rehabilitation of Motor Symptoms: Insights from the Use of Wearableshttps://www.dovepress.com/better-understanding-rehabilitation-of-motor-symptoms-insights-from-th-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchWed, 19 Mar 2025 20:45:00 +1300https://doi.org/10.2147/POR.S396198Real-World Biologic Use Patterns in Severe Asthma, 2015–2021: The CLEAR Studyhttps://www.dovepress.com/real-world-biologic-use-patterns-in-severe-asthma-20152021-the-clear-s-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchTue, 18 Mar 2025 19:55:00 +1300https://doi.org/10.2147/POR.S497033A Prospective Observational Study to Evaluate the Actual Use of 1% Pimecrolimus in Chinese Patients with Mild-to-Moderate Atopic Dermatitis Affecting Sensitive Skin Areashttps://www.dovepress.com/a-prospective-observational-study-to-evaluate-the-actual-use-of-1-pime-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchFri, 07 Mar 2025 03:35:00 +1300https://doi.org/10.2147/POR.S496970Treatment Patterns, Adverse Events, and Clinical Outcomes with Steroidal Mineralocorticoid Receptor Antagonists: A Retrospective Analysis of Administrative Claims Data (RELICS)https://www.dovepress.com/treatment-patterns-adverse-events-and-clinical-outcomes-with-steroidal-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchWed, 26 Feb 2025 05:00:00 +1300https://doi.org/10.2147/POR.S489791Validation of Mortality Data Sources Compared to the National Death Index in the Healthcare Integrated Research Databasehttps://www.dovepress.com/validation-of-mortality-data-sources-compared-to-the-national-death-in-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchFri, 07 Feb 2025 06:50:00 +1300https://doi.org/10.2147/POR.S498221Review of Challenges in Performing Real-World Evidence Studies for Nonprescription Productshttps://www.dovepress.com/review-of-challenges-in-performing-real-world-evidence-studies-for-non-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchThu, 23 Jan 2025 00:10:00 +1300https://doi.org/10.2147/POR.S504709Measuring Diagnostic Quality: The Capacity of Routinely Collected Data and Applications to Chronic Respiratory Diseasehttps://www.dovepress.com/measuring-diagnostic-quality-the-capacity-of-routinely-collected-data--peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchThu, 16 Jan 2025 21:30:00 +1300https://doi.org/10.2147/POR.S430705Detection of Patient-Level Immunotherapy-Related Adverse Events (irAEs) from Clinical Narratives of Electronic Health Records: A High-Sensitivity Artificial Intelligence Modelhttps://www.dovepress.com/detection-of-patient-level-immunotherapy-related-adverse-events-iraes--peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchFri, 20 Dec 2024 20:10:00 +1300https://doi.org/10.2147/POR.S468253Validation and Final Results from the First Cardiac Lead Post-Approval Study Using Real-World Datahttps://www.dovepress.com/validation-and-final-results-from-the-first-cardiac-lead-post-approval-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchThu, 19 Dec 2024 21:25:00 +1300https://doi.org/10.2147/POR.S499248Preserved Ratio Impaired Spirometry in US Primary Care Patients Diagnosed with Chronic Obstructive Pulmonary Diseasehttps://www.dovepress.com/preserved-ratio-impaired-spirometry-in-us-primary-care-patients-diagno-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchFri, 13 Dec 2024 23:55:00 +1300https://doi.org/10.2147/POR.S478721Patient Characteristics, Management, and Outcomes of Adult Asthma in a Singapore Population: Data from the SDG-CARE Asthma Registryhttps://www.dovepress.com/patient-characteristics-management-and-outcomes-of-adult-asthma-in-a-s-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchSat, 07 Dec 2024 01:35:00 +1300https://doi.org/10.2147/POR.S477225Improving the Transparency and Replicability of Consensus Methods: Respiratory Medicine as a Case Examplehttps://www.dovepress.com/improving-the-transparency-and-replicability-of-consensus-methods-resp-peer-reviewed-fulltext-article-PORPragmatic and Observational ResearchTue, 15 Oct 2024 14:45:00 +1300https://doi.org/10.2147/POR.S478163