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Clinical Ophthalmology

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Anti-VEGF Therapies in Retinal Disorders: Recent Advances, Biosimilars, and Future Directions

The advent of anti-VEGF (vascular endothelial growth factor) therapies has revolutionized the management of retinal disorders, offering significant improvements in vision and quality of life for millions of patients worldwide. These therapies, initially developed for conditions such as age-related macular degeneration (AMD) and diabetic macular edema (DME), have set new standards in ophthalmic care by effectively controlling disease progression and reducing the need for more invasive treatments.

Intravitreal Bevacizumab Alone Vs Combined With Topical Timolol-Dorzolamide or Dorzolamide for Diabetic Macular Edema: A Systematic Review and Meta-Analysis

Hubayni RA, Qedair J, Bukhari ZM, Alsudais AS, Badghaish OS, Bawazir RO, AlQahtani AS, Almarzouki H

Clinical Ophthalmology 2025, 19:1007-1019

Published Date: 22 March 2025

Efficacy and Safety of Aflibercept Biosimilars Relative to Reference Aflibercept Therapy for Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis

Aljuhani HS, Hubayni RA, Qedair J, Bukhari ZM, Alzahrani A, Bawazir RO, Badghaish OS, Alqahtani F

Clinical Ophthalmology 2025, 19:1911-1918

Published Date: 19 June 2025

Discordance Among Patients and Ophthalmologists Regarding the Burden of Intravitreal Injections

Robinson K, Cooper SJ, Persaud S, Frederick JL, Singh RP

Clinical Ophthalmology 2025, 19:2637-2645

Published Date: 8 August 2025